TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Integrative Physiology
AddressOne Baylor Plaza
Houston, TX 77030
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    R01EY012825     (ZHANG, PUMIN)Sep 1, 2000 - Aug 31, 2006
    Role: Principal Investigator

    R03EY013993     (ZHANG, PUMIN)May 1, 2002 - Mar 31, 2005
    Gene expression in lens fiber cell differentiation
    Role: Principal Investigator

    R21DK063964     (ZHANG, PUMIN)Aug 5, 2003 - Jul 31, 2006
    A New Transgenic Approach for the Kidney
    Role: Principal Investigator

    R03EY014745     (ZHANG, PUMIN)Dec 1, 2003 - Nov 30, 2006
    Development of A Transgenic RNAi Technology for the Eye
    Role: Principal Investigator

    U01DK070214     (ZHANG, PUMIN)Apr 1, 2005 - Mar 31, 2010
    Generation /Analysis of Mice Carrying GFP-tagged Genes in Kidney Development
    Role: Principal Investigator

    R01CA116097     (ZHANG, PUMIN)Jun 1, 2005 - Jun 30, 2017
    The Function of Cdc14B in DNA Damage Repair and Tumorigenesis
    Role: Principal Investigator

    R01CA122623     (ZHANG, PUMIN)Oct 1, 2006 - Oct 31, 2018
    Spindle Assembly Checkpoint, Chromosome Stability, and Cancer
    Role: Principal Investigator

    R01EY019075     (ZHANG, PUMIN)Jun 1, 2009 - Nov 30, 2011
    Notch Signaling and Lens Development
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cai M, Sun X, Wang W, Lian Z, Wu P, Han S, Chen H, Zhang P. Disruption of peroxisome function leads to metabolic stress, mTOR inhibition, and lethality in liver cancer cells. Cancer Lett. 2018 05 01; 421:82-93. PMID: 29458144.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    2. Fang X, Lu G, Ha K, Lin H, Du Y, Zuo Q, Fu Y, Zou C, Zhang P. Acetylation of TIP60 at K104 is essential for metabolic stress-induced apoptosis in cells of hepatocellular cancer. Exp Cell Res. 2018 01 15; 362(2):279-286. PMID: 29174981.
      Citations: 4     Fields:    Translation:HumansCells
    3. Fang X, Lin H, Wang X, Zuo Q, Qin J, Zhang P. The NEK1 interactor, C21ORF2, is required for efficient DNA damage repair. Acta Biochim Biophys Sin (Shanghai). 2015 Oct; 47(10):834-41. PMID: 26290490.
      Citations: 26     Fields:    Translation:HumansCells
    4. Lin H, Ha K, Lu G, Fang X, Cheng R, Zuo Q, Zhang P. Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair. Mol Cell Biol. 2015 Nov; 35(21):3657-68. PMID: 26283732.
      Citations: 15     Fields:    Translation:AnimalsCells
    5. Lee CS, Dagnino-Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, Georgiou DK, Poché RA, Swank MW, Long C, Ismailov II, Lanner J, Tran T, Dong K, Rodney GG, Dickinson ME, Beeton C, Zhang P, Dirksen RT, Hamilton SL. Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function. Skelet Muscle. 2015; 5:4. PMID: 25717360.
      Citations: 29     Fields:    
    6. Zhang A, Sieglaff DH, York JP, Suh JH, Ayers SD, Winnier GE, Kharitonenkov A, Pin C, Zhang P, Webb P, Xia X. Thyroid hormone receptor regulates most genes independently of fibroblast growth factor 21 in liver. J Endocrinol. 2015 Mar; 224(3):289-301. PMID: 25501997.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    7. Fan Y, Mao R, Yu Y, Liu S, Shi Z, Cheng J, Zhang H, An L, Zhao Y, Xu X, Chen Z, Kogiso M, Zhang D, Zhang H, Zhang P, Jung JU, Li X, Xu G, Yang J. USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase. J Exp Med. 2014 Feb 10; 211(2):313-28. PMID: 24493797.
      Citations: 88     Fields:    Translation:AnimalsCells
    8. Hatcher RJ, Dong J, Liu S, Bian G, Contreras A, Wang T, Hilsenbeck SG, Li Y, Zhang P. Pttg1/securin is required for the branching morphogenesis of the mammary gland and suppresses mammary tumorigenesis. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):1008-13. PMID: 24395789.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    9. Zhang W, Peng G, Lin SY, Zhang P. DNA damage response is suppressed by the high cyclin-dependent kinase 1 activity in mitotic mammalian cells. J Biol Chem. 2011 Oct 14; 286(41):35899-35905. PMID: 21878640.
      Citations: 22     Fields:    Translation:HumansCells
    10. Wei Z, Zhang P. Cdc14b: a new player in aging. Aging (Albany NY). 2011 May; 3(5):456. PMID: 21666283.
      Citations: 1     Fields:    
    11. Fang X, Zhang P. Aneuploidy and tumorigenesis. Semin Cell Dev Biol. 2011 Aug; 22(6):595-601. PMID: 21392584.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    12. Peddibhotla S, Wei Z, Papineni R, Lam MH, Rosen JM, Zhang P. The DNA damage effector Chk1 kinase regulates Cdc14B nucleolar shuttling during cell cycle progression. Cell Cycle. 2011 Feb 15; 10(4):671-9. PMID: 21301228.
      Citations: 9     Fields:    Translation:HumansCells
    13. Wei Z, Peddibhotla S, Lin H, Fang X, Li M, Rosen JM, Zhang P. Early-onset aging and defective DNA damage response in Cdc14b-deficient mice. Mol Cell Biol. 2011 Apr; 31(7):1470-7. PMID: 21262768.
      Citations: 22     Fields:    Translation:AnimalsCells
    14. Gao X, Shin YH, Li M, Wang F, Tong Q, Zhang P. The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. PLoS One. 2010 Nov 16; 5(11):e14005. PMID: 21103374.
      Citations: 99     Fields:    Translation:Animals
    15. Li M, Fang X, Baker DJ, Guo L, Gao X, Wei Z, Han S, van Deursen JM, Zhang P. The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14188-93. PMID: 20663956.
      Citations: 114     Fields:    Translation:Animals
    16. Li M, Shin YH, Hou L, Huang X, Wei Z, Klann E, Zhang P. The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory. Nat Cell Biol. 2008 Sep; 10(9):1083-9. PMID: 19160489.
      Citations: 87     Fields:    Translation:AnimalsCells
    17. Huang X, Andreu-Vieyra CV, York JP, Hatcher R, Lu T, Matzuk MM, Zhang P. Inhibitory phosphorylation of separase is essential for genome stability and viability of murine embryonic germ cells. PLoS Biol. 2008 Jan; 6(1):e15. PMID: 18232736.
      Citations: 16     Fields:    Translation:AnimalsCells
    18. Jia J, Lin M, Zhang L, York JP, Zhang P. The Notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression. Mol Cell Biol. 2007 Oct; 27(20):7236-47. PMID: 17709399.
      Citations: 48     Fields:    Translation:AnimalsCells
    19. Li M, York JP, Zhang P. Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos. Mol Cell Biol. 2007 May; 27(9):3481-8. PMID: 17325031.
      Citations: 48     Fields:    Translation:AnimalsCells
    20. Peng S, York JP, Zhang P. A transgenic approach for RNA interference-based genetic screening in mice. Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7):2252-6. PMID: 16461920.
      Citations: 22     Fields:    Translation:HumansAnimals
    21. Huang X, Hatcher R, York JP, Zhang P. Securin and separase phosphorylation act redundantly to maintain sister chromatid cohesion in mammalian cells. Mol Biol Cell. 2005 Oct; 16(10):4725-32. PMID: 16030258.
      Citations: 23     Fields:    Translation:AnimalsCells
    22. Huang X, Tran T, Zhang L, Hatcher R, Zhang P. DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint. Proc Natl Acad Sci U S A. 2005 Jan 25; 102(4):1065-70. PMID: 15650047.
      Citations: 53     Fields:    Translation:HumansCells
    23. Zhang P, Li MZ, Elledge SJ. Towards genetic genome projects: genomic library screening and gene-targeting vector construction in a single step. Nat Genet. 2002 Jan; 30(1):31-9. PMID: 11753384.
      Citations: 37     Fields:    Translation:AnimalsCells
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