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ALICA GOLDMAN

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Neurology
Address6501 Fannin St
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    Collapse Research 
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    R21NS113015     (GOLDMAN, ALICA M)Jul 1, 2019 - Jun 30, 2021
    NIH
    Isolating SUDEP Risk conferred by genomic co-variation in candidate SUDEP genes
    Role: Principal Investigator
    U01NS090362     (GOLDMAN, ALICA M)Sep 30, 2014 - Jul 31, 2020
    NIH
    SUDEP Research Alliance: Systems Medicine Core, Application 3 of 7
    Role: Principal Investigator
    U01NS090406     (GOLDMAN, ALICA M)Sep 30, 2014 - Jul 31, 2020
    NIH
    SUDEP Research Alliance: Clinical Network Core; Application 2 of 7
    Role: Principal Investigator
    R01NS067013     (GOLDMAN, ALICA M)Feb 1, 2011 - Jul 31, 2015
    NIH
    Copy Number Variants of Neuro-Cardiac Ion Channel Genes and the Risk of SUDEP
    Role: Principal Investigator
    K08NS047304     (GOLDMAN, ALICA M)Aug 1, 2004 - Jul 31, 2010
    NIH
    Ion channelopathies co-expressed in heart and brain
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ostendorf A, Waldman GJ, Jehi L, Ilyas M, Naritoku D, Goldman AM. Epilepsy Therapies Symposium | Do We Really "Outgrow" Seizures? Epilepsy Curr. 2024 Dec 19; 15357597241304501. PMID: 39712399; PMCID: PMC11660101.
      Citations:    
    2. Fazli Besheli B, Sha Z, Gavvala JR, Karamursel S, Quach M, Swamy CP, Ayyoubi AH, Goldman AM, Curry DJ, Sheth SA, Darrow D, Miller KJ, Francis DJ, Worrell GA, Henry TR, Ince NF. Using high-frequency oscillations from brief intraoperative neural recordings to predict the seizure onset zone. Commun Med (Lond). 2024 Nov 25; 4(1):243. PMID: 39587325; PMCID: PMC11589742.
      Citations:    
    3. Welty TE, Conway JM, Bainbridge J, Park K, Vossler DG, Patel AA, Goldman A. The Fundamentals of Antiseizure Medications: A Through Z. Epilepsy Curr. 2024 Oct 07; 15357597241281838. PMID: 39539402; PMCID: PMC11556333.
      Citations:    
    4. Chen S, Abou-Khalil BW, Afawi Z, Ali QZ, Amadori E, Anderson A, Anderson J, Andrade DM, Annesi G, Arslan M, Auce P, Bahlo M, Baker MD, Balagura G, Balestrini S, Banks E, Barba C, Barboza K, Bartolomei F, Bass N, Baum LW, Baumgartner TH, Baykan B, Bebek N, Becker F, Bennett CA, Beydoun A, Bianchini C, Bisulli F, Blackwood D, Blatt I, Borggr?fe I, Bosselmann C, Braatz V, Brand H, Brockmann K, Buono RJ, Busch RM, Caglayan SH, Canafoglia L, Canavati C, Castellotti B, Cavalleri GL, Cerrato F, Chassoux F, Cherian C, Cherny SS, Cheung CL, Chou IJ, Chung SK, Churchhouse C, Ciullo V, Clark PO, Cole AJ, Cosico M, Cossette P, Cotsapas C, Cusick C, Daly MJ, Davis LK, Jonghe P, Delanty N, Dennig D, Depondt C, Derambure P, Devinsky O, Di Vito L, Dickerson F, Dlugos DJ, Doccini V, Doherty CP, El-Naggar H, Ellis CA, Epstein L, Evans M, Faucon A, Feng YA, Ferguson L, Ferraro TN, Da Silva IF, Ferri L, Feucht M, Fields MC, Fitzgerald M, Fonferko-Shadrach B, Fortunato F, Franceschetti S, French JA, Freri E, Fu JM, Gabriel S, Gagliardi M, Gambardella A, Gauthier L, Giangregorio T, Gili T, Glauser TA, Goldberg E, Goldman A, Goldstein DB, Granata T, Grant R, Greenberg DA, Guerrini R, Gundogdu-Eken A, Gupta N, Haas K, Hakonarson H, Haryanyan G, H?usler M, Hegde M, Heinzen EL, Helbig I, Hengsbach C, Heyne H, Hirose S, Hirsch E, Ho CJ, Hoeper O, Howrigan DP, Hucks D, Hung PC, Iacomino M, Inoue Y, Inuzuka LM, Ishii A, Jehi L, Johnson MR, Johnstone M, K?lvi?inen R, Kanaan M, Kara B, Kariuki SM, Kegele J, Kesim Y, Khoueiry-Zgheib N, Khoury J, King C, Klein KM, Kluger G, Knake S, Kok F, Korczyn AD, Korinthenberg R, Koupparis A, Kousiappa I, Krause R, Krenn M, Krestel H, Krey I, Kunz WS, Kurlemann G, Kuzniecky RI, Kwan P, La Vega-Talbott M, Labate A, Lacey A, Lal D, La??uthov? P, Lauxmann S, Lawthom C, Leech SL, Lehesjoki AE, Lemke JR, Lerche H, Lesca G, Leu C, Lewin N, Lewis-Smith D, Li GH, Liao C, Licchetta L, Lin CH, Lin KL, Linnankivi T, Lo W, Lowenstein DH, Lowther C, Lubbers L, Lui CHT, Macedo-Souza LI, Madeleyn R, Madia F, Magri S, Maillard L, Marcuse L, Marques P, Marson AG, Matthews AG, May P, Mayer T, McArdle W, McCarroll SM, McGoldrick P, McGraw CM, McIntosh A, McQuillan A, Meador KJ, Mei D, Michel V, Millichap JJ, Minardi R, Montomoli M, Mostacci B, Muccioli L, Muhle H, M?ller-Schl?ter K, Najm IM, Nasreddine W, Neaves S, Neubauer BA, Newton CRJC, Noebels JL, Northstone K, Novod S, O'Brien TJ, Owusu-Agyei S, ?zkara ?, Palotie A, Papacostas SS, Parrini E, Pato C, Pato M, Pendziwiat M, Pennell PB, Petrovski S, Pickrell WO, Pinsky R, Pinto D, Pippucci T, Piras F, Piras F, Poduri A, Pondrelli F, Posthuma D, Powell RHW, Privitera M, Rademacher A, Ragona F, Ramirez-Hamouz B, Rau S, Raynes HR, Rees MI, Regan BM, Reif A, Reinthaler E, Rheims S, Ring SM, Riva A, Rojas E, Rosenow F, Ryvlin P, Saarela A, Sadleir LG, Salman B, Salmon A, Salpietro V, Sammarra I, Scala M, Schachter S, Schaller A, Schankin CJ, Scheffer IE, Schneider N, Schubert-Bast S, Schulze-Bonhage A, Scudieri P, Sedl?ckov? L, Shain C, Sham PC, Shiedley BR, Siena SA, Sills GJ, Sisodiya SM, Smoller JW, Solomonson M, Spalletta G, Sparks KR, Sperling MR, Stamberger H, Steinhoff BJ, Stephani U, ?terbov? K, Stewart WC, Stipa C, Striano P, Strzelczyk A, Surges R, Suzuki T, Talarico M, Talkowski ME, Taneja RS, Tanteles GA, Timonen O, Timpson NJ, Tinuper P, Todaro M, Topaloglu P, Tsai MH, Tumiene B, Turkdogan D, Ugur-Iseri S, Utkus A, Vaidiswaran P, Valton L, van Baalen A, Vari MS, Vetro A, Vlckov? M, von Brauchitsch S, von Spiczak S, Wagner RG, Watts N, Weber YG, Weckhuysen S, Widdess-Walsh P, Wiebe S, Wolf SM, Wolff M, Wolking S, Wong I, von Wrede R, Wu D, Yamakawa K, Yapici Z, Yis U, Yolken R, Y?cesan E, Zagaglia S, Zahnert F, Zara F, Zimprich F, Zizovic M, Zsurka G, Neale BM, Berkovic SF. Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes. medRxiv. 2024 Sep 20. PMID: 36865150; PMCID: PMC9980234.
      Citations:    
    5. Ayyoubi AH, Fazli Besheli B, Quach MM, Gavvala JR, Goldman AM, Swamy CP, Bartoli E, Curry DJ, Sheth SA, Francis DJ, Ince NF. Benchmarking signal quality and spatiotemporal distribution of interictal spikes in prolonged human iEEG recordings using CorTec wireless brain interchange. Sci Rep. 2024 02 08; 14(1):2652. PMID: 38332136; PMCID: PMC10853182.
      Citations: 4     Fields:    Translation:Humans
    6. Brunklaus A, George AL, Lal D, Heinzen EL, Goldman AM. Prophecy or empiricism? Clinical value of predicting versus determining genetic variant functions. Epilepsia. 2023 11; 64(11):2909-2913. PMID: 37562820.
      Citations:    
    7. Goldman AM. Oncogenic Pathways Provide Clue to the Etiology of Human Mesial Temporal Lobe Epilepsy. JAMA Neurol. 2023 06 01; 80(6):546-547. PMID: 37126324.
      Citations:    Fields:    Translation:Humans
    8. Goldman AM, Thio KLL. SLC35A2-Related Epilepsy: Global Neuronal Consequences of a Focal Disruption in Glycosylation. Neurology. 2023 01 31; 100(5):225-226. PMID: 36307216.
      Citations:    Fields:    Translation:HumansCells
    9. Goldman AM. Can a Mouse Help Us Unravel the Mysteries of CDKL5-Related Epilepsy? Epilepsy Curr. 2022 Nov-Dec; 22(6):375-377. PMID: 36426191; PMCID: PMC9661619.
      Citations:    
    10. Van Loo KMJ, Carvill GL, Becker AJ, Conboy K, Goldman AM, Kobow K, Lopes-Cendes I, Reid CA, van Vliet EA, Henshall DC. Epigenetic genes and epilepsy - emerging mechanisms and clinical applications. Nat Rev Neurol. 2022 09; 18(9):530-543. PMID: 35859062.
      Citations:    
    11. Torrealba-Acosta G, Butt H, Edmondson EA, Willaert R, Viswanathan A, Goldman AM. A Neurostimulation-Triggered Trigeminal Neuralgia-like Pain: Risk Factors and Management. Neurol Clin Pract. 2021 Oct; 11(5):e760-e762. PMID: 34840901; PMCID: PMC8610532.
      Citations:    
    12. Massey CA, Thompson SJ, Ostrom RW, Drabek J, Sveinsson OA, Haas EA, Mena OJ, Goldman AM, Noebels JL, Tomson T. X-linked serotonin 2C receptor is associated with a non-canonical pathway for sudden unexpected death in epilepsy. Brain Commun. 2021; 3(3):fcab149. PMID: 34396109; PMCID: PMC8361391.
      Citations: 1     
    13. Goldman AM. Peri-ictal Brainstem-Driven Posturing and Its Meaning. Neurology. 2021 01 19; 96(3):89-90. PMID: 33268564.
      Citations:    Fields:    Translation:Humans
    14. Nair DR, Laxer KD, Weber PB, Murro AM, Park YD, Barkley GL, Smith BJ, Gwinn RP, Doherty MJ, Noe KH, Zimmerman RS, Bergey GK, Anderson WS, Heck C, Liu CY, Lee RW, Sadler T, Duckrow RB, Hirsch LJ, Wharen RE, Tatum W, Srinivasan S, McKhann GM, Agostini MA, Alexopoulos AV, Jobst BC, Roberts DW, Salanova V, Witt TC, Cash SS, Cole AJ, Worrell GA, Lundstrom BN, Edwards JC, Halford JJ, Spencer DC, Ernst L, Skidmore CT, Sperling MR, Miller I, Geller EB, Berg MJ, Fessler AJ, Rutecki P, Goldman AM, Mizrahi EM, Gross RE, Shields DC, Schwartz TH, Labar DR, Fountain NB, Elias WJ, Olejniczak PW, Villemarette-Pittman NR, Eisenschenk S, Roper SN, Boggs JG, Courtney TA, Sun FT, Seale CG, Miller KL, Skarpaas TL, Morrell MJ, RNS System LTT Study. Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy. Neurology. 2020 09 01; 95(9):e1244-e1256. PMID: 32690786; PMCID: PMC7538230.
      Citations: 53     Fields:    Translation:Humans
    15. Goldman AM. What does a defect in N-glycosylation mean for neuronal migration and function? Neurol Genet. 2020 Aug; 6(4):e490. PMID: 32754647; PMCID: PMC7357410.
      Citations:    
    16. Kobow K, Reid CA, van Vliet EA, Becker AJ, Carvill GL, Goldman AM, Hirose S, Lopes-Cendes I, Khiari HM, Poduri A, Johnson MR, Henshall DC. Epigenetics explained: a topic "primer" for the epilepsy community by the ILAE Genetics/Epigenetics Task Force. Epileptic Disord. 2020 Apr 01; 22(2):127-141. PMID: 32301721.
      Citations:    
    17. Goldman A, Telegrafi A, Boughton A, Gamble C, Van Ness P, Douglas G, Si YC, Shad Z, Kaplan E, Dineen R, Mattioli F, Hayot G, Drouot N, Isidor B, Courraud J, Hinckelmann MV, Mau-Them FT, Sellier C, Moutton S, Quartier A, Jean N, Grotto S, Nambot S, Chelly J, Golzio C, Charlet-Berguerand N, Mandel JL, Piton A. De Novo Frameshift Variants in the Neuronal Splicing Factor NOVA2 Result in a Common C-Terminal Extension and Cause a Severe Form of Neurodevelopmental Disorder. Am J Hum Genet. 2020 04 02; 106(4):438-452. PMID: 32197073; PMCID: PMC7118572.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    18. Montier L, Haneef Z, Gavvala J, Yoshor D, North R, Verla T, Van Ness PC, Drabek J, Goldman AM. A somatic mutation in MEN1 gene detected in periventricular nodular heterotopia tissue obtained from depth electrodes. Epilepsia. 2019 10; 60(10):e104-e109. PMID: 31489630; PMCID: PMC6852559.
      Citations: 3     Fields:    Translation:Humans
    19. Assia Batzir N, Bhagwat PK, Eble TN, Liu P, Eng CM, Elsea SH, Robak LA, Scaglia F, Goldman AM, Dhar SU, Wangler MF. De novo missense variant in the GTPase effector domain (GED) of DNM1L leads to static encephalopathy and seizures. Cold Spring Harb Mol Case Stud. 2019 06; 5(3). PMID: 30850373; PMCID: PMC6549558.
      Citations: 11     Fields:    Translation:HumansCells
    20. Marafi D, Suter B, Schultz R, Glaze D, Pavlik VN, Goldman AM. Spectrum and time course of epilepsy and the associated cognitive decline in MECP2 duplication syndrome. Neurology. 2019 01 08; 92(2):e108-e114. PMID: 30552298; PMCID: PMC6340341.
      Citations: 10     Fields:    Translation:Humans
    21. Frasier CR, Zhang H, Offord J, Dang LT, Auerbach DS, Shi H, Chen C, Goldman AM, Eckhardt LL, Bezzerides VJ, Parent JM, Isom LL. Channelopathy as a SUDEP Biomarker in Dravet Syndrome Patient-Derived Cardiac Myocytes. Stem Cell Reports. 2018 09 11; 11(3):626-634. PMID: 30146492; PMCID: PMC6135724.
      Citations:    
    22. Mueller SG, Nei M, Bateman LM, Knowlton R, Laxer KD, Friedman D, Devinsky O, Goldman AM. Brainstem network disruption: A pathway to sudden unexplained death in epilepsy? Hum Brain Mapp. 2018 12; 39(12):4820-4830. PMID: 30096213; PMCID: PMC6866413.
      Citations:    
    23. Jobst BC, Kapur R, Barkley GL, Bazil CW, Berg MJ, Bergey GK, Boggs JG, Cash SS, Cole AJ, Duchowny MS, Duckrow RB, Edwards JC, Eisenschenk S, Fessler AJ, Fountain NB, Geller EB, Goldman AM, Goodman RR, Gross RE, Gwinn RP, Heck C, Herekar AA, Hirsch LJ, King-Stephens D, Labar DR, Marsh WR, Meador KJ, Miller I, Mizrahi EM, Murro AM, Nair DR, Noe KH, Olejniczak PW, Park YD, Rutecki P, Salanova V, Sheth RD, Skidmore C, Smith MC, Spencer DC, Srinivasan S, Tatum W, Van Ness P, Vossler DG, Wharen RE, Worrell GA, Yoshor D, Zimmerman RS, Skarpaas TL, Morrell MJ. Brain-responsive neurostimulation in patients with medically intractable seizures arising from eloquent and other neocortical areas. Epilepsia. 2017 06; 58(6):1005-1014. PMID: 28387951.
      Citations: 48     Fields:    Translation:Humans
    24. Goldman AM, LaFrance WC, Benke T, Asato M, Drane D, Pack A, Syed T, Doss R, Lhatoo S, Fureman B, Dingledine R, American Epilepsy Society (AES)/National Institute of Neurological Disorders and Stroke (NINDS) Epil. 2014 Epilepsy Benchmarks Area IV: Limit or Prevent Adverse Consequence of Seizures and Their Treatment Across The Lifespan. Epilepsy Curr. 2016 May-Jun; 16(3):198-205. PMID: 27330453; PMCID: PMC4913859.
      Citations: 6     
    25. Goldman AM, Behr ER, Semsarian C, Bagnall RD, Sisodiya S, Cooper PN. Sudden unexpected death in epilepsy genetics: Molecular diagnostics and prevention. Epilepsia. 2016 Jan; 57 Suppl 1:17-25. PMID: 26749013; PMCID: PMC5034873.
      Citations:    
    26. King-Stephens D, Mirro E, Weber PB, Laxer KD, Van Ness PC, Salanova V, Spencer DC, Heck CN, Goldman A, Jobst B, Shields DC, Bergey GK, Eisenschenk S, Worrell GA, Rossi MA, Gross RE, Cole AJ, Sperling MR, Nair DR, Gwinn RP, Park YD, Rutecki PA, Fountain NB, Wharen RE, Hirsch LJ, Miller IO, Barkley GL, Edwards JC, Geller EB, Berg MJ, Sadler TL, Sun FT, Morrell MJ. Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography. Epilepsia. 2015 Jun; 56(6):959-67. PMID: 25988840; PMCID: PMC4676303.
      Citations: 48     Fields:    Translation:Humans
    27. Goldman AM. Mechanisms of sudden unexplained death in epilepsy. Curr Opin Neurol. 2015 Apr; 28(2):166-74. PMID: 25734955; PMCID: PMC5034868.
      Citations:    
    28. Bergey GK, Morrell MJ, Mizrahi EM, Goldman A, King-Stephens D, Nair D, Srinivasan S, Jobst B, Gross RE, Shields DC, Barkley G, Salanova V, Olejniczak P, Cole A, Cash SS, Noe K, Wharen R, Worrell G, Murro AM, Edwards J, Duchowny M, Spencer D, Smith M, Geller E, Gwinn R, Skidmore C, Eisenschenk S, Berg M, Heck C, Van Ness P, Fountain N, Rutecki P, Massey A, O'Donovan C, Labar D, Duckrow RB, Hirsch LJ, Courtney T, Sun FT, Seale CG. Long-term treatment with responsive brain stimulation in adults with refractory partial seizures. Neurology. 2015 Feb 24; 84(8):810-7. PMID: 25616485; PMCID: PMC4339127.
      Citations: 152     Fields:    Translation:Humans
    29. Goldman AM, Tuchman R. Commentary: Genetic testing in epilepsy: what do patients and families want to know? Epilepsia. 2014 Nov; 55(11):1703-4. PMID: 25377513.
      Citations:    
    30. Chen TT, Klassen TL, Goldman AM, Marini C, Guerrini R, Noebels JL. Novel brain expression of ClC-1 chloride channels and enrichment of CLCN1 variants in epilepsy. Neurology. 2013 Mar 19; 80(12):1078-85. PMID: 23408874; PMCID: PMC3662306.
      Citations: 24     Fields:    Translation:HumansAnimals
    31. Klassen TL, Drabek J, Noebels JL, Goldman AM, von R?den EL. Comparative analytical utility of DNA derived from alternative human specimens for molecular autopsy and diagnostics. J Mol Diagn. 2012 Sep; 14(5):451-7. PMID: 22796560; PMCID: PMC5803546.
      Citations: 4     Fields:    Translation:Humans
    32. McGuire AL, Oliver JM, Slashinski MJ, Graves JL, Wang T, Kelly PA, Fisher W, Lau CC, Goss J, Okcu M, Treadwell-Deering D, Goldman AM, Noebels JL, Hilsenbeck SG. To share or not to share: a randomized trial of consent for data sharing in genome research. Genet Med. 2011 Nov; 13(11):948-55. PMID: 21785360; PMCID: PMC3203320.
      Citations: 48     Fields:    Translation:Humans
    33. Klassen T, Davis C, Goldman A, Burgess D, Chen T, Wheeler D, McPherson J, Bourquin T, Lewis L, Villasana D, Morgan M, Muzny D, Gibbs R, Noebels J. Exome sequencing of ion channel genes reveals complex profiles confounding personal risk assessment in epilepsy. Cell. 2011 Jun 24; 145(7):1036-48. PMID: 21703448; PMCID: PMC3131217.
      Citations: 161     Fields:    Translation:HumansCells
    34. Bi W, Yan J, Shi X, Yuva-Paylor LA, Antalffy BA, Goldman A, Yoo JW, Noebels JL, Armstrong DL, Paylor R, Lupski JR. Rai1 deficiency in mice causes learning impairment and motor dysfunction, whereas Rai1 heterozygous mice display minimal behavioral phenotypes. Hum Mol Genet. 2007 Aug 01; 16(15):1802-13. PMID: 17517686.
      Citations: 38     Fields:    Translation:Animals
    35. Goldman AM, Potocki L, Walz K, Lynch JK, Glaze DG, Lupski JR, Noebels JL. Epilepsy and chromosomal rearrangements in Smith-Magenis Syndrome [del(17)(p11.2p11.2)]. J Child Neurol. 2006 Feb; 21(2):93-8. PMID: 16566870.
      Citations: 13     Fields:    Translation:HumansCells
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