RICHARD A. BOND

TitleProfessor
InstitutionUniversity of Houston College of Pharmacy
DepartmentPharmacological & Pharmaceutical Sciences
AddressHealth 2 4849 Calhoun Road, Room 5015
Houston, TX 77204-5037
Houston TX 77204-5037
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    R29GM054805     (BOND, RICHARD AGUSTIN)Sep 30, 1997 - Sep 28, 2002
    NIH/NIGMS
    REVISING RECEPTOR THEORY FOR G PROTEIN-COUPLED RECEPTORS
    Role: Principal Investigator

    R01AI079236     (BOND, RICHARD AGUSTIN)Jun 28, 2010 - May 31, 2011
    NIH/NIAID
    Mechanisms of beta-blocker induced improvements in asthma
    Role: Principal Investigator

    R56AI079236     (BOND, RICHARD AGUSTIN)Apr 15, 2012 - Sep 30, 2014
    NIH/NIAID
    Mechanisms of Beta-blocker Induced Improvements in Asthma
    Role: Principal Investigator

    R01AI110007     (WALKER, JULIA K L)Jun 18, 2014 - May 31, 2019
    NIH/NIAID
    Optimizing Beta-Adrenoceptor Signaling Bias in Asthma
    Role: Co-Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kunz HE, Agha NH, Hussain M, LaVoy EC, Smith KA, Mylabathula P, Diak D, Baker FL, O'Connor DP, Bond RA, Katsanis E, Bollard CM, Simpson RJ. The effects of ß1 and ß1+2 adrenergic receptor blockade on the exercise-induced mobilization and ex vivo expansion of virus-specific T cells: implications for cellular therapy and the anti-viral immune effects of exercise. Cell Stress Chaperones. 2020 Aug 10. PMID: 32779001.
      Citations:    Fields:    
    2. Zaidi S, Atrooz F, Valdez D, Liu H, Kochi C, Bond RA, Salim S. Protective effect of propranolol and nadolol on social defeat-induced behavioral impairments in rats. Neurosci Lett. 2020 04 23; 725:134892. PMID: 32165259.
      Citations:    Fields:    
    3. Baker FL, Bigley AB, Agha NH, Pedlar CR, O'Connor DP, Bond RA, Bollard CM, Katsanis E, Simpson RJ. Systemic ß-Adrenergic Receptor Activation Augments the ex vivo Expansion and Anti-Tumor Activity of V?9Vd2 T-Cells. Front Immunol. 2019; 10:3082. PMID: 32038628.
      Citations: 2     Fields:    
    4. Islas JF, Abbasgholizadeh R, Dacso C, Potaman VN, Navran S, Bond RA, Iyer D, Birla R, Schwartz RJ. ß-Adrenergic stimuli and rotating suspension culture enhance conversion of human adipogenic mesenchymal stem cells into highly conductive cardiac progenitors. J Tissue Eng Regen Med. 2020 02; 14(2):306-318. PMID: 31821703.
      Citations: 1     Fields:    
    5. Boulanger CM, Baretella O, Blaise G, Bond RA, Cai Y, Chan CKY, Chataigneau T, Chen MJ, Chen H, Cheng Y, Clement DL, Cohen RA, Collis M, Danser AHJ, de Mey J, Detremmerie CMS, Duprez D, Feletou M, Flavahan N, Gao Y, Guo Y, Hoeffner U, Houston DS, Huang IB, Huang Y, Iliano S, Junquero D, Katusic ZS, Komori K, Lee MYK, Leung SWS, Li Z, Liang SC, Liu JTC, Luscher TF, Michel F, Miller VM, Mombouli JV, Morrison K, Muldoon SM, O'Rourke S, Perrault L, Quignard JF, Rusch NJ, Sanchez-Ferrer CF, Schini-Kerth V, Shen K, Shi Y, Song E, Sun KWY, Taddei S, Tang EHC, Tuncer M, van den Ende R, Vedernikov Y, Verbeuren TJ, Webb C, Weigert A, Wong KHK, Xu C, Yang K, Ying F, Zellers T, Zhao Y, Zou Q, Shimokawa H. Tribute to Paul M. Vanhoutte, MD, PhD (1940-2019). Arterioscler Thromb Vasc Biol. 2019 12; 39(12):2445-2447. PMID: 31770032.
      Citations:    Fields:    
    6. Geng C, Rajapakshe K, Shah SS, Shou J, Eedunuri VK, Foley C, Fiskus W, Rajendran M, Chew SA, Zimmermann M, Bond R, He B, Coarfa C, Mitsiades N. Correction: Androgen Receptor Is the Key Transcriptional Mediator of the Tumor Suppressor SPOP in Prostate Cancer. Cancer Res. 2019 Sep 01; 79(17):4552. PMID: 31481421.
      Citations:    Fields:    
    7. Michel MC, Bond RA, Summers RJ. Adrenoceptors-New roles for old players. Br J Pharmacol. 2019 07; 176(14):2339-2342. PMID: 31240712.
      Citations: 1     Fields:    Translation:HumansAnimals
    8. Bond RA, Lucero Garcia-Rojas EY, Hegde A, Walker JKL. Therapeutic Potential of Targeting ß-Arrestin. Front Pharmacol. 2019; 10:124. PMID: 30894814.
      Citations:    
    9. Graff RM, Kunz HE, Agha NH, Baker FL, Laughlin M, Bigley AB, Markofski MM, LaVoy EC, Katsanis E, Bond RA, Bollard CM, Simpson RJ. ß2-Adrenergic receptor signaling mediates the preferential mobilization of differentiated subsets of CD8+ T-cells, NK-cells and non-classical monocytes in response to acute exercise in humans. Brain Behav Immun. 2018 11; 74:143-153. PMID: 30172948.
      Citations: 7     Fields:    Translation:HumansCells
    10. Nguyen LP, Al-Sawalha NA, Parra S, Pokkunuri I, Omoluabi O, Okulate AA, Windham Li E, Hazen M, Gonzalez-Granado JM, Daly CJ, McGrath JC, Tuvim MJ, Knoll BJ, Dickey BF, Bond RA. ß2-Adrenoceptor signaling in airway epithelial cells promotes eosinophilic inflammation, mucous metaplasia, and airway contractility. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):E9163-E9171. PMID: 29073113.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    11. Agha NH, Baker FL, Kunz HE, Graff R, Azadan R, Dolan C, Laughlin MS, Hosing C, Markofski MM, Bond RA, Bollard CM, Simpson RJ. Vigorous exercise mobilizes CD34+ hematopoietic stem cells to peripheral blood via the ß2-adrenergic receptor. Brain Behav Immun. 2018 02; 68:66-75. PMID: 29017969.
      Citations: 4     Fields:    Translation:HumansCells
    12. Joshi R, Valdez D, Kim H, Eikenburg DC, Knoll BJ, Bond RA. Effects of ß-blockers on house dust mite-driven murine models pre- and post-development of an asthma phenotype. Pulm Pharmacol Ther. 2017 Oct; 46:30-40. PMID: 28729042.
      Citations: 2     Fields:    Translation:AnimalsCells
    13. Forkuo GS, Kim H, Thanawala VJ, Al-Sawalha N, Valdez D, Joshi R, Parra S, Pera T, Gonnella PA, Knoll BJ, Walker JK, Penn RB, Bond RA. Phosphodiesterase 4 Inhibitors Attenuate the Asthma Phenotype Produced by ß2-Adrenoceptor Agonists in Phenylethanolamine N-Methyltransferase-Knockout Mice. Am J Respir Cell Mol Biol. 2016 08; 55(2):234-42. PMID: 26909542.
      Citations: 8     Fields:    Translation:AnimalsCells
    14. Bond RA, Thanawala VJ, Parra S, Leff P. Differences in asthma study models and the effectiveness of ß2 -adrenoceptor ligands: response to Lipworth et al. Br J Pharmacol. 2016 Jan; 173(1):250-1. PMID: 26687674.
      Citations:    Fields:    Translation:Animals
    15. Knight JM, Mak G, Shaw J, Porter P, McDermott C, Roberts L, You R, Yuan X, Millien VO, Qian Y, Song LZ, Frazier V, Kim C, Kim JJ, Bond RA, Milner JD, Zhang Y, Mandal PK, Luong A, Kheradmand F, McMurray JS, Corry DB. Long-Acting Beta Agonists Enhance Allergic Airway Disease. PLoS One. 2015; 10(11):e0142212. PMID: 26605551.
      Citations: 3     Fields:    Translation:HumansAnimals
    16. Thanawala VJ, Valdez DJ, Joshi R, Forkuo GS, Parra S, Knoll BJ, Bouvier M, Leff P, Bond RA. ß-Blockers have differential effects on the murine asthma phenotype. Br J Pharmacol. 2015 Oct; 172(20):4833-46. PMID: 26211486.
      Citations: 8     Fields:    Translation:Animals
    17. Al-Sawalha N, Pokkunuri I, Omoluabi O, Kim H, Thanawala VJ, Hernandez A, Bond RA, Knoll BJ. Epinephrine Activation of the ß2-Adrenoceptor Is Required for IL-13-Induced Mucin Production in Human Bronchial Epithelial Cells. PLoS One. 2015; 10(7):e0132559. PMID: 26161982.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    18. Curtis MJ, Bond RA, Spina D, Ahluwalia A, Alexander SP, Giembycz MA, Gilchrist A, Hoyer D, Insel PA, Izzo AA, Lawrence AJ, MacEwan DJ, Moon LD, Wonnacott S, Weston AH, McGrath JC. Experimental design and analysis and their reporting: new guidance for publication in BJP. Br J Pharmacol. 2015 Jul; 172(14):3461-71. PMID: 26114403.
      Citations: 222     Fields:    Translation:HumansAnimals
    19. Michel MC, Seifert R, Bond RA. Dynamic bias and its implications for GPCR drug discovery. Nat Rev Drug Discov. 2014 Nov; 13(11):869. PMID: 25323926.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    20. Geng C, Rajapakshe K, Shah SS, Shou J, Eedunuri VK, Foley C, Fiskus W, Rajendran M, Chew SA, Zimmermann M, Bond R, He B, Coarfa C, Mitsiades N. Androgen receptor is the key transcriptional mediator of the tumor suppressor SPOP in prostate cancer. Cancer Res. 2014 Oct 01; 74(19):5631-43. PMID: 25274033.
      Citations: 48     Fields:    Translation:HumansCells
    21. Thanawala VJ, Forkuo GS, Stallaert W, Leff P, Bouvier M, Bond R. Ligand bias prevents class equality among beta-blockers. Curr Opin Pharmacol. 2014 Jun; 16:50-7. PMID: 24681351.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    22. Bond RA. The intrinsic bias of generalizations. Am J Respir Crit Care Med. 2014 Feb 01; 189(3):359. PMID: 24484333.
      Citations: 3     Fields:    Translation:Humans
    23. Penn RB, Bond RA, Walker JK. GPCRs and arrestins in airways: implications for asthma. Handb Exp Pharmacol. 2014; 219:387-403. PMID: 24292841.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    24. Forkuo GS, Thanawala VJ, Al-Sawalha N, Bond RA, Walker JK. Reply: Adverse effects of long-acting beta-agonists on airway hyperresponsiveness. Am J Respir Cell Mol Biol. 2013 Sep; 49(3):502. PMID: 23991664.
      Citations:    Fields:    Translation:Animals
    25. Vollert C, Forkuo GS, Bond RA, Eriksen JL. Chronic treatment with DCPCX, an adenosine A(1) antagonist, worsens long-term memory. Neurosci Lett. 2013 Aug 26; 548:296-300. PMID: 23748072.
      Citations: 4     Fields:    Translation:Animals
    26. Geng C, He B, Xu L, Barbieri CE, Eedunuri VK, Chew SA, Zimmermann M, Bond R, Shou J, Li C, Blattner M, Lonard DM, Demichelis F, Coarfa C, Rubin MA, Zhou P, O'Malley BW, Mitsiades N. Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover. Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):6997-7002. PMID: 23559371.
      Citations: 83     Fields:    Translation:HumansCells
    27. Nguyen LP, Singh B, Okulate AA, Alfaro VY, Tuvim MJ, Dickey BF, Bond RA. Complementary anti-inflammatory effects of a ß-blocker and a corticosteroid in an asthma model. Naunyn Schmiedebergs Arch Pharmacol. 2012 Feb; 385(2):203-10. PMID: 21964666.
      Citations: 3     Fields:    Translation:Animals
    28. Walker JK, Penn RB, Hanania NA, Dickey BF, Bond RA. New perspectives regarding ß(2) -adrenoceptor ligands in the treatment of asthma. Br J Pharmacol. 2011 May; 163(1):18-28. PMID: 21175591.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    29. Peng H, Bond RA, Knoll BJ. The effects of acute and chronic nadolol treatment on ß2AR signaling in HEK293 cells. Naunyn Schmiedebergs Arch Pharmacol. 2011 Feb; 383(2):209-16. PMID: 21225244.
      Citations: 1     Fields:    Translation:HumansCells
    30. Hanania NA, Mannava B, Franklin AE, Lipworth BJ, Williamson PA, Garner WJ, Dickey BF, Bond RA. Response to salbutamol in patients with mild asthma treated with nadolol. Eur Respir J. 2010 Oct; 36(4):963-5. PMID: 20889466.
      Citations: 15     Fields:    Translation:Humans
    31. Dickey BF, Walker JK, Hanania NA, Bond RA. beta-Adrenoceptor inverse agonists in asthma. Curr Opin Pharmacol. 2010 Jun; 10(3):254-9. PMID: 20399707.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    32. Hanania NA, Dickey BF, Bond RA. Clinical implications of the intrinsic efficacy of beta-adrenoceptor drugs in asthma: full, partial and inverse agonism. Curr Opin Pulm Med. 2010 Jan; 16(1):1-5. PMID: 19887938.
      Citations: 11     Fields:    Translation:Humans
    33. Nguyen LP, Lin R, Parra S, Omoluabi O, Hanania NA, Tuvim MJ, Knoll BJ, Dickey BF, Bond RA. Beta2-adrenoceptor signaling is required for the development of an asthma phenotype in a murine model. Proc Natl Acad Sci U S A. 2009 Feb 17; 106(7):2435-40. PMID: 19171883.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    34. Nguyen LP, Omoluabi O, Parra S, Frieske JM, Clement C, Ammar-Aouchiche Z, Ho SB, Ehre C, Kesimer M, Knoll BJ, Tuvim MJ, Dickey BF, Bond RA. Chronic exposure to beta-blockers attenuates inflammation and mucin content in a murine asthma model. Am J Respir Cell Mol Biol. 2008 Mar; 38(3):256-62. PMID: 18096872.
      Citations: 57     Fields:    Translation:Animals
    35. Hanania NA, Singh S, El-Wali R, Flashner M, Franklin AE, Garner WJ, Dickey BF, Parra S, Ruoss S, Shardonofsky F, O'Connor BJ, Page C, Bond RA. The safety and effects of the beta-blocker, nadolol, in mild asthma: an open-label pilot study. Pulm Pharmacol Ther. 2008; 21(1):134-41. PMID: 17703976.
      Citations: 46     Fields:    Translation:HumansCTClinical Trials
    36. Lin R, Peng H, Nguyen LP, Dudekula NB, Shardonofsky F, Knoll BJ, Parra S, Bond RA. Changes in beta 2-adrenoceptor and other signaling proteins produced by chronic administration of 'beta-blockers' in a murine asthma model. Pulm Pharmacol Ther. 2008; 21(1):115-24. PMID: 17689122.
      Citations: 30     Fields:    Translation:Animals
    37. Bond RA, Spina D, Parra S, Page CP. Getting to the heart of asthma: can "beta blockers" be useful to treat asthma? Pharmacol Ther. 2007 Sep; 115(3):360-74. PMID: 17681610.
      Citations: 10     Fields:    Translation:Humans
    38. Parra S, Bond RA. Inverse agonism: from curiosity to accepted dogma, but is it clinically relevant? Curr Opin Pharmacol. 2007 Apr; 7(2):146-50. PMID: 17284360.
      Citations: 13     Fields:    Translation:Humans
    39. Dudekula N, Arora V, Callaerts-Vegh Z, Bond RA. The temporal hormesis of drug therapies. Dose Response. 2006 May 01; 3(3):414-24. PMID: 18648614.
      Citations:    
    40. Bond RA, Ijzerman AP. Recent developments in constitutive receptor activity and inverse agonism, and their potential for GPCR drug discovery. Trends Pharmacol Sci. 2006 Feb; 27(2):92-6. PMID: 16406086.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    41. Bond RA. A proposal for a national program reporting beneficial drug responses, analogous to the existing program to detect adverse drug responses. Med Hypotheses. 2006; 66(1):10-3. PMID: 16198061.
      Citations:    Fields:    
    42. Xiao RP, Zhu W, Zheng M, Chakir K, Bond R, Lakatta EG, Cheng H. Subtype-specific beta-adrenoceptor signaling pathways in the heart and their potential clinical implications. Trends Pharmacol Sci. 2004 Jul; 25(7):358-65. PMID: 15219978.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    43. Callaerts-Vegh Z, Evans KL, Dudekula N, Cuba D, Knoll BJ, Callaerts PF, Giles H, Shardonofsky FR, Bond RA. Effects of acute and chronic administration of beta-adrenoceptor ligands on airway function in a murine model of asthma. Proc Natl Acad Sci U S A. 2004 Apr 06; 101(14):4948-53. PMID: 15069206.
      Citations: 61     Fields:    Translation:AnimalsCells
    44. Xiao RP, Zhang SJ, Chakir K, Avdonin P, Zhu W, Bond RA, Balke CW, Lakatta EG, Cheng H. Enhanced G(i) signaling selectively negates beta2-adrenergic receptor (AR)--but not beta1-AR-mediated positive inotropic effect in myocytes from failing rat hearts. Circulation. 2003 Sep 30; 108(13):1633-9. PMID: 12975249.
      Citations: 45     Fields:    Translation:AnimalsCells
    45. Flesch M, Höper A, Dell'Italia L, Evans K, Bond R, Peshock R, Diwan A, Brinsa TA, Wei CC, Sivasubramanian N, Spinale FG, Mann DL. Activation and functional significance of the renin-angiotensin system in mice with cardiac restricted overexpression of tumor necrosis factor. Circulation. 2003 Aug 05; 108(5):598-604. PMID: 12874189.
      Citations: 16     Fields:    Translation:Animals
    46. Callaerts-Vegh Z, Evans KL, Shipley GL, Davies PJ, Cuba DL, Gurji HA, Giles H, Bond RA. Effects of different beta adrenoceptor ligands in mice with permanent occlusion of the left anterior descending coronary artery. Br J Pharmacol. 2003 Apr; 138(8):1505-16. PMID: 12721106.
      Citations: 5     Fields:    Translation:Animals
    47. Evans KL, Bond RA, Corry DB, Shardonofsky FR. Frequency dependence of respiratory system mechanics during induced constriction in a murine model of asthma. J Appl Physiol (1985). 2003 Jan; 94(1):245-52. PMID: 12486022.
      Citations: 10     Fields:    Translation:Animals
    48. Bond RA. Can intellectualism stifle scientific discovery? Nat Rev Drug Discov. 2002 Oct; 1(10):825-9. PMID: 12360260.
      Citations: 6     Fields:    Translation:HumansAnimals
    49. Liu X, Callaerts-Vegh Z, Evans KL, Bond RA. Chronic infusion of beta-adrenoceptor antagonist and inverse agonists decreases elevated protein kinase A activity in transgenic mice with cardiac-specific overexpression of human beta 2-adrenoceptor. J Cardiovasc Pharmacol. 2002 Sep; 40(3):448-55. PMID: 12198331.
      Citations: 1     Fields:    Translation:HumansAnimals
    50. Bond RA. Is paradoxical pharmacology a strategy worth pursuing? Trends Pharmacol Sci. 2001 Jun; 22(6):273-6. PMID: 11395153.
      Citations: 20     Fields:    Translation:Humans
    51. Guyton K, Bond R, Reilly C, Gilkeson G, Halushka P, Cook J. Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation. J Leukoc Biol. 2001 Apr; 69(4):631-8. PMID: 11310850.
      Citations: 10     Fields:    Translation:AnimalsCells
    52. Franceschini D, Orr-Urtreger A, Yu W, Mackey LY, Bond RA, Armstrong D, Patrick JW, Beaudet AL, De Biasi M. Altered baroreflex responses in alpha7 deficient mice. Behav Brain Res. 2000 Aug; 113(1-2):3-10. PMID: 10942027.
      Citations: 17     Fields:    Translation:AnimalsCells
    53. Nagaraja S, Iyer S, Liu X, Eichberg J, Bond RA. Treatment with inverse agonists enhances baseline atrial contractility in transgenic mice with chronic beta2-adrenoceptor activation. Br J Pharmacol. 1999 Jul; 127(5):1099-104. PMID: 10455254.
      Citations: 8     Fields:    Translation:Animals
    54. Clarke WP, Bond RA. The elusive nature of intrinsic efficacy. Trends Pharmacol Sci. 1998 Jul; 19(7):270-6. PMID: 9703760.
      Citations: 18     Fields:    
    55. Milligan G, Bond RA. Inverse agonism and the regulation of receptor number. Trends Pharmacol Sci. 1997 Dec; 18(12):468-74. PMID: 9458695.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    56. Gürdal H, Bond RA, Johnson MD, Friedman E, Onaran HO. An efficacy-dependent effect of cardiac overexpression of beta2-adrenoceptor on ligand affinity in transgenic mice. Mol Pharmacol. 1997 Aug; 52(2):187-94. PMID: 9271340.
      Citations: 1     Fields:    Translation:AnimalsCells
    57. Samama P, Bond RA, Rockman HA, Milano CA, Lefkowitz RJ. Ligand-induced overexpression of a constitutively active beta2-adrenergic receptor: pharmacological creation of a phenotype in transgenic mice. Proc Natl Acad Sci U S A. 1997 Jan 07; 94(1):137-41. PMID: 8990174.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    58. Jaber M, Koch WJ, Rockman H, Smith B, Bond RA, Sulik KK, Ross J, Lefkowitz RJ, Caron MG, Giros B. Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function. Proc Natl Acad Sci U S A. 1996 Nov 12; 93(23):12974-9. PMID: 8917529.
      Citations: 105     Fields:    Translation:Animals
    59. Nagao T, Nakashima M, Smart FW, Bond RA, Morrison KJ, Vanhoutte PM. Potentiation of endothelium-dependent hyperpolarization to serotonin by dietary intake of NC 020, a defined fish oil, in the porcine coronary artery. J Cardiovasc Pharmacol. 1995 Nov; 26(5):679-81. PMID: 8637179.
      Citations: 1     Fields:    Translation:Animals
    60. Koch WJ, Rockman HA, Samama P, Hamilton RA, Bond RA, Milano CA, Lefkowitz RJ. Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor. Science. 1995 Jun 02; 268(5215):1350-3. PMID: 7761854.
      Citations: 188     Fields:    Translation:AnimalsCells
    61. Bond RA, Leff P, Johnson TD, Milano CA, Rockman HA, McMinn TR, Apparsundaram S, Hyek MF, Kenakin TP, Allen LF, et al. Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor. Nature. 1995 Mar 16; 374(6519):272-6. PMID: 7885448.
      Citations: 87     Fields:    Translation:Animals
    62. Milano CA, Allen LF, Dolber PC, Johnson TD, Rockman HA, Bond RA, Lefkowitz RJ. Marked enhancement in myocardial function resulting from overexpression of a human beta-adrenergic receptor gene. J Thorac Cardiovasc Surg. 1995 Feb; 109(2):236-41. PMID: 7853876.
      Citations: 5     Fields:    Translation:HumansAnimals
    63. Milligan G, Bond RA, Lee M. Inverse agonism: pharmacological curiosity or potential therapeutic strategy? Trends Pharmacol Sci. 1995 Jan; 16(1):10-3. PMID: 7732597.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    64. Hieble JP, Bond RA. New directions in adrenoceptor pharmacology. Trends Pharmacol Sci. 1994 Nov; 15(11):397-9. PMID: 7855898.
      Citations: 3     Fields:    Translation:Humans
    65. Milano CA, Dolber PC, Rockman HA, Bond RA, Venable ME, Allen LF, Lefkowitz RJ. Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy. Proc Natl Acad Sci U S A. 1994 Oct 11; 91(21):10109-13. PMID: 7937846.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    66. Milano CA, Allen LF, Rockman HA, Dolber PC, McMinn TR, Chien KR, Johnson TD, Bond RA, Lefkowitz RJ. Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor. Science. 1994 Apr 22; 264(5158):582-6. PMID: 8160017.
      Citations: 158     Fields:    Translation:HumansAnimalsCells
    67. Boulanger CM, Hughes H, Bond RA, Rafla E, Vanhoutte PM. Effects of S9977 on adrenergic neurotransmission. Gen Pharmacol. 1993 Mar; 24(2):429-34. PMID: 8387054.
      Citations:    Fields:    Translation:AnimalsCells
    68. Schini VB, Bond R, Gao Y, Illiano S, Junquero DC, Mombouli JV, Nagao T, Smart F, Vanhoutte PM. The sydnonimine C87-3754 evokes endothelium-independent relaxations and prevents endothelium-dependent contractions in blood vessels of the dog. J Cardiovasc Pharmacol. 1993; 22 Suppl 7:S10-6. PMID: 7504762.
      Citations: 1     Fields:    Translation:Animals
    69. Bond RA, Vanhoutte PM. Interaction of tertatolol at the "atypical" or beta 3-adrenoceptor in guinea-pig ileum. Gen Pharmacol. 1992 Mar; 23(2):171-6. PMID: 1353468.
      Citations: 2     Fields:    Translation:Animals
    70. Gao YS, Nagao T, Bond RA, Janssens WJ, Vanhoutte PM. Nebivolol induces endothelium-dependent relaxations of canine coronary arteries. J Cardiovasc Pharmacol. 1991 Jun; 17(6):964-9. PMID: 1714022.
      Citations: 26     Fields:    Translation:Animals
    71. Blue DR, Bond RA, Adham N, Delmendo R, Michel AD, Eglen RM, Whiting RL, Clarke DE. Antagonist characterization of atypical beta adrenoceptors in guinea pig ileum: blockade by alprenolol and dihydroalprenolol. J Pharmacol Exp Ther. 1990 Mar; 252(3):1034-42. PMID: 1969469.
      Citations: 16     Fields:    Translation:Animals
    72. Bond RA, Craig DA, Charlton KG, Ornstein AG, Clarke DE. Partial agonistic activity of GR43175 at the inhibitory prejunctional 5-HT1-like receptor in rat kidney. J Auton Pharmacol. 1989 Jun; 9(3):201-10. PMID: 2545718.
      Citations: 4     Fields:    Translation:Animals
    73. Bond RA, Ornstein AG, Clarke DE. Unsurmountable antagonism to 5-hydroxytryptamine in rat kidney results from pseudoirreversible inhibition rather than multiple receptors or allosteric receptor modulation. J Pharmacol Exp Ther. 1989 May; 249(2):401-10. PMID: 2724131.
      Citations: 8     Fields:    Translation:AnimalsCells
    74. Bond RA, Clarke DE. Agonist and antagonist characterization of a putative adrenoceptor with distinct pharmacological properties from the alpha- and beta-subtypes. Br J Pharmacol. 1988 Nov; 95(3):723-34. PMID: 2905184.
      Citations: 44     Fields:    Translation:Animals
    75. Bond RA, Clarke DE. A response to isoprenaline unrelated to alpha- and beta-adrenoceptor agonism. Br J Pharmacol. 1987 Jul; 91(3):683-6. PMID: 2886175.
      Citations: 11     Fields:    Translation:Animals
    76. Bond RA, Charlton KG, Clarke DE. Evidence for a receptor mediated action of norepinephrine distinct from alpha- and beta-adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol. 1986 Nov; 334(3):261-6. PMID: 2880303.
      Citations: 6     Fields:    Translation:Animals
    77. Bond RA, Charlton KG, Clarke DE. Responses to norepinephrine resistant to inhibition by alpha and beta adrenoceptor antagonists. J Pharmacol Exp Ther. 1986 Feb; 236(2):408-15. PMID: 2868118.
      Citations: 12     Fields:    Translation:Animals
    78. Charlton KG, Bond RA, Clarke DE. An inhibitory prejunctional 5-HT1-like receptor in the isolated perfused rat kidney. Apparent distinction from the 5-HT1A, 5-HT1B and 5-HT1C subtypes. Naunyn Schmiedebergs Arch Pharmacol. 1986 Jan; 332(1):8-15. PMID: 3951568.
      Citations: 20     Fields:    Translation:Animals
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