AMIR SHARAFKHANEH

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address2002 HOLCOMBE
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Maghsoudi A, Azarian M, Sharafkhaneh A, Jones MB, Nozari H, Kryger M, Ramezani A, Razjouyan J, Maghsoudi A, Azarian M, Sharafkhaneh A, Jones MB, Ramezani A, Razjouyan J. Age modulates the predictive value of self-reported sleepiness for all-cause mortality risk: insights from a comprehensive national database of veterans. J Clin Sleep Med. 2024 Nov 01; 20(11):1785-1792. PMID: 38935061; PMCID: PMC11530978.
      Citations:    Fields:    Translation:Humans
    2. Khazaie H, Sharafkhaneh A, Zakiei A, Crew EC. A clinical algorithm for diagnosis and treatment of insomnia in adults: an updated review. CNS Spectr. 2024 Oct 31; 1-11. PMID: 39479779.
      Citations:    Fields:    
    3. Khazaie H, Aghazadeh M, Zakiei A, Maazinezhad S, Tavallaie A, Moghbel B, Azarian M, Mozafari F, Norouzi E, Sweetman A, Sharafkhaneh A. Co-morbid Insomnia and Sleep Apnea (COMISA) in a large sample of Iranian: prevalence and associations in a sleep clinic population. Sleep Breath. 2024 Dec; 28(6):2693-2700. PMID: 39186100.
      Citations:    Fields:    Translation:Humans
    4. Jones MB, Schenck CH, Azarian M, Jorge RE, Sharafkhaneh A, Razjouyan J, Jones MB, Schenck CH, Azarian M, Jorge RE, Sharafkhaneh A, Razjouyan J. Validation of electronic diagnostic codes for rapid eye movement sleep behavior disorder. J Clin Sleep Med. 2024 Aug 01; 20(8):1387-1389. PMID: 38661648; PMCID: PMC11294125.
      Citations:    Fields:    Translation:Humans
    5. Mostafaei SH, Tanha J, Sharafkhaneh A. A novel deep learning model based on transformer and cross modality attention for classification of sleep stages. J Biomed Inform. 2024 Sep; 157:104689. PMID: 39029770.
      Citations:    Fields:    Translation:Humans
    6. Sharafkhaneh A, Razjouyan J. The Saga of COVID-19 in Chronic Lung Disease: History Repeats Itself. Ann Am Thorac Soc. 2024 Jul; 21(7):1001-1002. PMID: 38949606; PMCID: PMC11284321.
      Citations:    Fields:    Translation:HumansCells
    7. Ramezani A, Azarian M, Sharafkhaneh A, Maghsoudi A, Jones MB, Penzel T, Razjouyan J. Age modifies the association between severe sleep apnea and all-cause mortality. Sleep Med. 2024 Sep; 121:18-24. PMID: 38901302; PMCID: PMC11385665.
      Citations:    Fields:    Translation:Humans
    8. Ramezani A, Sharafkhaneh A, BaHammam AS, Kuna ST, Razjouyan J. Effects of COVID-19 on Sleep Services Use and Its Recovery. Nat Sci Sleep. 2024; 16:761-768. PMID: 38882925; PMCID: PMC11179655.
      Citations: 1     
    9. Razjouyan J, Hanania NA, Nowakowski S, Agrawal R, Sharafkhaneh A. Identification of sleep phenotypes in COPD using machine learning-based cluster analysis. Respir Med. 2024 06; 227:107641. PMID: 38710399; PMCID: PMC11218872.
      Citations:    Fields:    Translation:Humans
    10. Vaeli Zadeh A, Dinparastisaleh R, Vaezi A, Bandyopadhyay D, Rubinstein I, Baig HZ, Calderon-Candelario R, Hashemi Shahraki A, Kawasaki T, Magnusson JM, Larsson LO, Sharafkhaneh A, Herazo-Maya JD, Lee AS, Mirsaeidi M. Risk of 30-Day All-Cause Readmission in Interstitial Lung Disease Patients after COVID-19: National-Level Data. Ann Am Thorac Soc. 2024 Mar; 21(3):428-437. PMID: 38134434; PMCID: PMC10913765.
      Citations: 1     Fields:    Translation:Humans
    11. Talha KM, Waqar E, DiNino EK, Asghar A, Sperling LS, Sharafkhaneh A, Virani SS, Ballantyne CM, Nambi V, Minhas AMK. Trends in sleep apnea and heart failure related mortality in the United States from 1999 to 2019. Curr Probl Cardiol. 2024 Feb; 49(2):102342. PMID: 38103816.
      Citations: 1     Fields:    Translation:Humans
    12. Moradi MT, Fadaei R, Sharafkhaneh A, Khazaie H, Gozal D. The role of lncRNAs in intermittent hypoxia and sleep Apnea: A review of experimental and clinical evidence. Sleep Med. 2024 01; 113:188-197. PMID: 38043330.
      Citations:    Fields:    Translation:HumansAnimals
    13. Jones MB, Agrawal R, Sharafkhaneh A, Bhatti G, Li R, Marsh L, Jorge RE. Pimavanserin 34 mg at Bedtime for the Treatment of Insomnia in 6 Veterans With Posttraumatic Stress Disorder. J Clin Psychiatry. 2023 11 06; 84(6). PMID: 37943987; PMCID: PMC11414078.
      Citations:    Fields:    
    14. Sharafkhaneh A, Agrawal R, Nambi V, BaHammam A, Razjouyan J. Obesity paradox or hypoxia preconditioning: How obstructive sleep apnea modifies the Obesity-MI relationship. Sleep Med. 2023 10; 110:132-136. PMID: 37574613; PMCID: PMC10529841.
      Citations: 1     Fields:    Translation:Humans
    15. Agrawal R, Sharafkhaneh A, Nambi V, BaHammam A, Razjouyan J. Obstructive sleep apnea modulates clinical outcomes post-acute myocardial infarction: A large longitudinal veterans' dataset report. Respir Med. 2023 05; 211:107214. PMID: 36924849; PMCID: PMC10122709.
      Citations: 1     Fields:    Translation:Humans
    16. Agrawal R, Sharafkhaneh A, Gottlieb DJ, Nowakowski S, Razjouyan J. Mortality Patterns Associated with Central Sleep Apnea among Veterans: A Large, Retrospective, Longitudinal Report. Ann Am Thorac Soc. 2023 03; 20(3):450-455. PMID: 36375082; PMCID: PMC9993148.
      Citations: 2     Fields:    Translation:Humans
    17. Mehrdad M, Azarian M, Sharafkhaneh A, Alavi A, Leili EK, Rad AH, Dalili S. The association between OSA and glycemic control in diabetes. Int J Prev Med. 2023; 14:26. PMID: 37033275; PMCID: PMC10080574.
      Citations:    
    18. Park C, Tavakoli-Tabasi S, Sharafkhaneh A, Seligman BJ, Hicken B, Amos CI, Chou A, Razjouyan J. Inflammatory Biomarkers Differ among Hospitalized Veterans Infected with Alpha, Delta, and Omicron SARS-CoV-2 Variants. Int J Environ Res Public Health. 2023 02 08; 20(4). PMID: 36833680; PMCID: PMC9959816.
      Citations: 3     Fields:    Translation:HumansCells
    19. Maghsoudi A, Nowakowski S, Agrawal R, Sharafkhaneh A, Kunik ME, Naik AD, Xu H, Razjouyan J. Sentiment Analysis of Insomnia-Related Tweets via a Combination of Transformers Using Dempster-Shafer Theory: Pre- and Peri-COVID-19 Pandemic Retrospective Study. J Med Internet Res. 2022 12 27; 24(12):e41517. PMID: 36417585; PMCID: PMC9822178.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    20. Khazaie H, Sadeghi M, Khazaie S, Hirshkowitz M, Sharafkhaneh A. Dual orexin receptor antagonists for treatment of insomnia: A systematic review and meta-analysis on randomized, double-blind, placebo-controlled trials of suvorexant and lemborexant. Front Psychiatry. 2022; 13:1070522. PMID: 36578296; PMCID: PMC9792135.
      Citations:    
    21. Bryant MS, Fedson SE, Schutz A, Cornwell LD, Sharafkhaneh A, Venkata B. Telerehabilitation: Future of Phase II Cardiac Rehabilitation: Review of Preliminary Outcomes. J Med Syst. 2022 Nov 11; 46(12):94. PMID: 36367614; PMCID: PMC9650175.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    22. Rahman M, Nowakowski S, Agrawal R, Naik A, Sharafkhaneh A, Razjouyan J. Validation of a Natural Language Processing Algorithm for the Extraction of the Sleep Parameters from the Polysomnography Reports. Healthcare (Basel). 2022 Sep 22; 10(10). PMID: 36292283; PMCID: PMC9602175.
      Citations: 1     
    23. Nono Djotsa ABS, Helmer DA, Park C, Lynch KE, Sharafkhaneh A, Naik AD, Razjouyan J, Amos CI. Assessing Smoking Status and Risk of SARS-CoV-2 Infection: A Machine Learning Approach among Veterans. Healthcare (Basel). 2022 Jul 04; 10(7). PMID: 35885771; PMCID: PMC9319659.
      Citations:    
    24. Javaherforooshzadeh F, Amjadzadeh M, Haybar H, Sharafkhaneh A. Impact of Obstructive Sleep Apnea Diagnosed Using the STOP-Bang Questionnaire Scale on Postoperative Complications Following Major Cardiac Surgery: A Prospective Observational Cohort Study. Cureus. 2022 Jun; 14(6):e26102. PMID: 35875276; PMCID: PMC9297118.
      Citations:    
    25. Razjouyan J, Helmer DA, Lynch KE, Hanania NA, Klotman PE, Sharafkhaneh A, Amos CI. Smoking Status and Factors associated with COVID-19 In-Hospital Mortality among US Veterans. Nicotine Tob Res. 2022 03 26; 24(5):785-793. PMID: 34693967; PMCID: PMC8586728.
      Citations: 2     Fields:    Translation:HumansCells
    26. Park C, Razjouyan J, Hanania NA, Helmer DA, Naik AD, Lynch KE, Amos CI, Sharafkhaneh A. Elevated Risk of Chronic Respiratory Conditions within 60 Days of COVID-19 Hospitalization in Veterans. Healthcare (Basel). 2022 Feb 04; 10(2). PMID: 35206914; PMCID: PMC8872176.
      Citations:    
    27. Sharafkhaneh A, Salari N, Khazaie S, Ghasemi H, Darvishi N, Hosseinian-Far A, Mohammadi M, Khazaie H. Telemedicine and insomnia: a comprehensive systematic review and meta-analysis. Sleep Med. 2022 02; 90:117-130. PMID: 35151065.
      Citations:    Fields:    Translation:Humans
    28. Agrawal R, Spiegelman AM, Bandi VD, Hirshkowitz M, Sharafkhaneh A. Obstructive sleep apnea in diabetic patients is associated with higher healthcare utilization. Sleep Breath. 2022 12; 26(4):1817-1820. PMID: 35034251.
      Citations:    Fields:    
    29. Mehrdad M, Azarian M, Sharafkhaneh A, Alavi A, Zare R, Hassanzadeh Rad A, Dalili S. Association Between Poor Sleep Quality and Glycemic Control in Adult Patients with Diabetes Referred to Endocrinology Clinic of Guilan: A Cross-sectional Study. Int J Endocrinol Metab. 2022 Jan; 20(1):e118077. PMID: 35432555; PMCID: PMC8994826.
      Citations:    
    30. Zhou H, Park C, Poursina O, Zahiri M, Nguyen H, Torres Ruiz I, Nguyen CK, Bryant MS, Sharafkhaneh A, Bandi VD, Najafi B. Harnessing Digital Health to Objectively Assess Functional Performance in Veterans with Chronic Obstructive Pulmonary Disease. Gerontology. 2022; 68(7):829-839. PMID: 34844245; PMCID: PMC9148378.
      Citations:    Fields:    Translation:Humans
    31. Agrawal R, Jones MB, Spiegelman AM, Bandi VD, Hirshkowitz M, Sharafkhaneh A. Presence of obstructive sleep apnea is associated with higher future readmissions and outpatient visits-a nationwide administrative dataset study. Sleep Med. 2022 01; 89:60-64. PMID: 34906781.
      Citations:    Fields:    Translation:Humans
    32. Jones MB, Agrawal R, Sharafkhaneh A, Kunik ME, Jorge RE, Marsh L. Dream Enactment Behaviors Associated With Posttraumatic Stress Disorder. J Neuropsychiatry Clin Neurosci. 2022; 34(2):124-131. PMID: 34763524.
      Citations:    Fields:    Translation:Humans
    33. Agrawal R, Ajami NJ, Malhotra S, Chen L, White DL, Sharafkhaneh A, Hoffman KL, Graham DY, El-Serag HB, Petrosino JF, Jiao L. Habitual Sleep Duration and the Colonic Mucosa-Associated Gut Microbiota in Humans-A Pilot Study. Clocks Sleep. 2021 Jul 01; 3(3):387-397. PMID: 34287254; PMCID: PMC8293063.
      Citations: 4     
    34. Park C, Mishra R, Sharafkhaneh A, Bryant MS, Nguyen C, Torres I, Naik AD, Najafi B. Digital Biomarker Representing Frailty Phenotypes: The Use of Machine Learning and Sensor-Based Sit-to-Stand Test. Sensors (Basel). 2021 May 08; 21(9). PMID: 34066716; PMCID: PMC8125840.
      Citations: 1     Fields:    Translation:Humans
    35. Razjouyan J, Helmer DA, Li A, Naik AD, Amos CI, Bandi V, Sharafkhaneh A. Differences in COVID-19-Related Testing and Healthcare Utilization by Race and Ethnicity in the Veterans Health Administration. J Racial Ethn Health Disparities. 2022 Apr; 9(2):519-526. PMID: 33694124; PMCID: PMC7945621.
      Citations: 4     Fields:    Translation:HumansCells
    36. Park C, Sharafkhaneh A, Bryant MS, Nguyen C, Torres I, Najafi B. Toward Remote Assessment of Physical Frailty Using Sensor-based Sit-to-stand Test. J Surg Res. 2021 07; 263:130-139. PMID: 33652175; PMCID: PMC9113630.
      Citations: 5     Fields:    Translation:Humans
    37. Agrawal R, Spiegelman AM, Bandi VD, Hirshkowitz M, Sharafkhaneh A. Healthcare utilization after elective surgery in patients with obstructive sleep apnea - analysis of a nationwide data set. Sleep Med. 2021 05; 81:294-299. PMID: 33744518.
      Citations:    Fields:    Translation:Humans
    38. Zahiri M, Wang C, Gardea M, Nguyen H, Shahbazi M, Sharafkhaneh A, Ruiz IT, Nguyen CK, Bryant MS, Najafi B. Remote Physical Frailty Monitoring-The Application of Deep Learning-Based Image Processing in Tele-Health. IEEE Access. 2020; 8:219391-219399. PMID: 33777594; PMCID: PMC7996628.
      Citations: 2     
    39. Bryant MS, Fedson SE, Sharafkhaneh A. Using Telehealth Cardiopulmonary Rehabilitation during the COVID-19 Pandemic. J Med Syst. 2020 05 28; 44(7):125. PMID: 32462352; PMCID: PMC7253228.
      Citations: 8     Fields:    Translation:CellsPHPublic Health
    40. Razjouyan J, Najafi B, Horstman M, Sharafkhaneh A, Amirmazaheri M, Zhou H, Kunik ME, Naik A. Toward Using Wearables to Remotely Monitor Cognitive Frailty in Community-Living Older Adults: An Observational Study. Sensors (Basel). 2020 Apr 14; 20(8). PMID: 32295301; PMCID: PMC7218861.
      Citations: 6     Fields:    Translation:Humans
    41. Asadpour H, Naghibi SM, Rahimi S, Sharafkhaneh A, Afshari Saleh L, Rezaee Talab F, Amini M, Nikzad F. Prolonged Sleep Apnea in Two Patients with a History of Opium Abuse -A Case Report. Iran J Otorhinolaryngol. 2020 Mar; 32(109):127-131. PMID: 32219080; PMCID: PMC7085923.
      Citations:    
    42. Fadaei R, Koushki M, Sharafkhaneh A, Moradi N, Ahmadi R, Rostampour M, Khazaie H. The impact of continuous positive airway pressure therapy on circulating levels of malondialdehyde: a systematic review and meta-analysis. Sleep Med. 2020 11; 75:27-36. PMID: 32853915.
      Citations:    Fields:    Translation:Humans
    43. Sawhney V, Seethamraju H, Bourguet C, Hirshkowitz M, Bandi V, Sharafkhaneh A. Non-respiratory complaints are main reasons for disturbed sleep post lung transplant. Sleep Med. 2020 06; 70:106-110. PMID: 32334187.
      Citations: 1     Fields:    Translation:Humans
    44. Razjouyan J, Lee H, Gilligan B, Lindberg C, Nguyen H, Canada K, Burton A, Sharafkhaneh A, Srinivasan K, Currim F, Ram S, Mehl MR, Goebel N, Lunden M, Bhangar S, Heerwagen J, Kampschroer K, Sternberg EM, Najafi B. Wellbuilt for wellbeing: Controlling relative humidity in the workplace matters for our health. Indoor Air. 2020 01; 30(1):167-179. PMID: 31663168; PMCID: PMC6973066.
      Citations: 3     Fields:    Translation:Humans
    45. Mohammadi H, Rezaei M, Sharafkhaneh A, Khazaie H, Ghadami MR. Serum testosterone/cortisol ratio in people with obstructive sleep apnea. J Clin Lab Anal. 2020 Jan; 34(1):e23011. PMID: 31549459; PMCID: PMC6977109.
      Citations: 7     Fields:    Translation:Humans
    46. Bryant MS, Bandi VD, Nguyen CK, Lan C, Henson HK, Sharafkhaneh A. Telehealth Pulmonary Rehabilitation for Patients With Severe Chronic Obstructive Pulmonary Disease. Fed Pract. 2019 Sep; 36(9):430-435. PMID: 31571812; PMCID: PMC6752812.
      Citations: 4     
    47. Agrawal R, Moghtader S, Ayyala U, Bandi V, Sharafkhaneh A. Update on management of stable chronic obstructive pulmonary disease. J Thorac Dis. 2019 Sep; 11(Suppl 14):S1800-S1809. PMID: 31632757; PMCID: PMC6783725.
      Citations: 4     
    48. Bazazan A, Dianat I, Bahrampour S, Talebian A, Zandi H, Sharafkhaneh A, Maleki-Ghahfarokhi A. Association of musculoskeletal disorders and workload with work schedule and job satisfaction among emergency nurses. Int Emerg Nurs. 2019 05; 44:8-13. PMID: 30902617.
      Citations: 6     Fields:    Translation:Humans
    49. Crothers K, Rodriguez CV, Nance RM, Akgun K, Shahrir S, Kim J, W Soo Hoo G, Sharafkhaneh A, Crane HM, Justice AC. Accuracy of electronic health record data for the diagnosis of chronic obstructive pulmonary disease in persons living with HIV and uninfected persons. Pharmacoepidemiol Drug Saf. 2019 02; 28(2):140-147. PMID: 29923258; PMCID: PMC6309326.
      Citations: 7     Fields:    Translation:Humans
    50. Hesselbacher S, Sharafkhaneh A. Resolution of Sleepwalking Behavior after Initiation of Sodium Oxybate in a Patient with Narcolepsy Type 2. Cureus. 2018 May 21; 10(5):e2662. PMID: 30042913; PMCID: PMC6054363.
      Citations:    
    51. Braddock M, Hanania NA, Sharafkhaneh A, Colice G, Carlsson M. Potential Risks Related to Modulating Interleukin-13 and Interleukin-4 Signalling: A Systematic Review. Drug Saf. 2018 05; 41(5):489-509. PMID: 29411337; PMCID: PMC5938313.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    52. Razjouyan J, Naik AD, Horstman MJ, Kunik ME, Amirmazaheri M, Zhou H, Sharafkhaneh A, Najafi B. Wearable Sensors and the Assessment of Frailty among Vulnerable Older Adults: An Observational Cohort Study. Sensors (Basel). 2018 Apr 26; 18(5). PMID: 29701640; PMCID: PMC5982667.
      Citations: 29     Fields:    Translation:Humans
    53. Razjouyan J, Lee H, Parthasarathy S, Mohler J, Sharafkhaneh A, Najafi B. Improving Sleep Quality Assessment Using Wearable Sensors by Including Information From Postural/Sleep Position Changes and Body Acceleration: A Comparison of Chest-Worn Sensors, Wrist Actigraphy, and Polysomnography. J Clin Sleep Med. 2017 Nov 15; 13(11):1301-1310. PMID: 28992827; PMCID: PMC5656479.
      Citations: 16     Fields:    Translation:Humans
    54. Boriek AM, Lopez MA, Velasco C, Bakir AA, Frolov A, Wynd S, Babb TG, Hanania NA, Hoffman EA, Sharafkhaneh A. Obesity modulates diaphragm curvature in subjects with and without COPD. Am J Physiol Regul Integr Comp Physiol. 2017 Nov 01; 313(5):R620-R629. PMID: 28903915; PMCID: PMC5792148.
      Citations: 6     Fields:    Translation:Humans
    55. Medrek SK, Sharafkhaneh A, Spiegelman AM, Kak A, Pandit LM. Admission for COPD Exacerbation Is Associated with the Clinical Diagnosis of Pulmonary Hypertension: Results from a Retrospective Longitudinal Study of a Veteran Population. COPD. 2017 Oct; 14(5):484-489. PMID: 28715281.
      Citations: 14     Fields:    Translation:Humans
    56. Khazaie H, Sharafkhaneh A, Khazaie S, Ghadami MR. A weight-independent association between atypical antipsychotic medications and obstructive sleep apnea. Sleep Breath. 2018 03; 22(1):109-114. PMID: 28707161.
      Citations: 4     Fields:    Translation:Humans
    57. Sharafkhaneh A, Tavakoli-Tabasi S, Musher D. Mortality in Patients Admitted for Concurrent COPD Exacerbation and Pneumonia. COPD. 2017 08; 14(4):462. PMID: 28594596.
      Citations: 1     Fields:    Translation:Humans
    58. Foroughi M, Malekmohammad M, Sharafkhaneh A, Emami H, Adimi P, Khoundabi B. Prevalence of Obstructive Sleep Apnea in a High-Risk Population Using the Stop-Bang Questionnaire in Tehran, Iran. Tanaffos. 2017; 16(3):217-224. PMID: 29849675; PMCID: PMC5960226.
      Citations: 11     
    59. Sharafkhaneh A, Spiegelman AM, Main K, Tavakoli-Tabasi S, Lan C, Musher D. Mortality in Patients Admitted for Concurrent COPD Exacerbation and Pneumonia. COPD. 2017 02; 14(1):23-29. PMID: 27661473.
      Citations: 3     Fields:    Translation:Humans
    60. Kim V, Zhao H, Boriek AM, Anzueto A, Soler X, Bhatt SP, Rennard SI, Wise R, Comellas A, Ramsdell JW, Kinney GL, Han MK, Martinez CH, Yen A, Black-Shinn J, Porszasz J, Criner GJ, Hanania NA, Sharafkhaneh A, Crapo JD, Make BJ, Silverman EK, Curtis JL, COPDGene Investigators. Persistent and Newly Developed Chronic Bronchitis Are Associated with Worse Outcomes in Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2016 07; 13(7):1016-25. PMID: 27158740; PMCID: PMC5015750.
      Citations: 22     Fields:    Translation:Humans
    61. Sharafkhaneh A, Hirshkowitz M. Can You Hear Me Now? J Clin Sleep Med. 2016 05 15; 12(5):641-2. PMID: 27092694; PMCID: PMC4865547.
      Citations:    Fields:    
    62. Mudambi L, Spiegelman A, Geron D, Hirshkowitz M, Mokhlesi B, Shaib Y, Velamuri S, Lan CO, Sharafkhaneh A. Obstructive Sleep Apnea Is Not Associated with Higher Health Care Use after Colonoscopy under Conscious Sedation. Ann Am Thorac Soc. 2016 Mar; 13(3):419-24. PMID: 26871998.
      Citations:    Fields:    Translation:Humans
    63. Kheirkhah P, Feng Q, Travis LM, Tavakoli-Tabasi S, Sharafkhaneh A. Prevalence, predictors and economic consequences of no-shows. BMC Health Serv Res. 2016 Jan 14; 16:13. PMID: 26769153; PMCID: PMC4714455.
      Citations: 52     Fields:    Translation:Humans
    64. Sharafkhaneh A, Katigbak J, Hirshkowitz M, Sharafkhaneh H, Sharafkhaneh SP, Ballantyne CM, Bozkurt B, Nambi V. Severity of hypoxia modulates effect of CPAP on myocardial stress as measured by highly sensitive troponin T. Respir Res. 2015 Oct 16; 16:126. PMID: 26475736; PMCID: PMC4609126.
      Citations: 2     Fields:    Translation:HumansCells
    65. Singh S, Kanbar-Agha F, Sharafkhaneh A. Novel Aerosol Delivery Devices. Semin Respir Crit Care Med. 2015 Aug; 36(4):543-51. PMID: 26238640.
      Citations: 2     Fields:    Translation:Humans
    66. Bujarski S, Parulekar AD, Sharafkhaneh A, Hanania NA. The asthma COPD overlap syndrome (ACOS). Curr Allergy Asthma Rep. 2015 Mar; 15(3):509. PMID: 25712010.
      Citations: 23     Fields:    Translation:Humans
    67. Attia EF, Wongtrakool C, Goetz MB, Rodriguez-Barradas MC, Rimland D, Brown ST, Soo Hoo GW, Kim J, Lee PJ, Schnapp LM, Sharafkhaneh A, Justice AC, Crothers K, Akg?n KM. Increased risk of radiographic emphysema in HIV is associated with elevated soluble CD14 and nadir CD4. Chest. 2014 Dec; 146(6):1543-1553. PMID: 25080158; PMCID: PMC4251616.
      Citations: 43     Fields:    Translation:Humans
    68. Hirshkowitz M, Sharafkhaneh A. A telemedicine program for diagnosis and management of sleep-disordered breathing: the fast-track for sleep apnea tele-sleep program. Semin Respir Crit Care Med. 2014 Oct; 35(5):560-70. PMID: 25353101.
      Citations: 5     Fields:    Translation:Humans
    69. Bowler RP, Kim V, Regan E, Santorico SA, Make BJ, Lynch DA, Hokanson JE, Washko GR, Bercz P, Soler X, Marchetti N, Criner GJ, Ramsdell J, Han MK, Demeo D, Anzueto A, Comellas A, Crapo JD, Dransfield M, Wells JM, Hersh CP, MacIntyre N, Martinez F, Nath HP, Niewoehner D, Sciurba F, Sharafkhaneh A, Silverman EK, van Beek EJR, Wilson C, Wendt C, Wise RA, Williams AAA. Prediction of acute respiratory disease in current and former smokers with and without COPD. Chest. 2014 Oct; 146(4):941-950. PMID: 24945159; PMCID: PMC4188150.
      Citations: 50     Fields:    Translation:Humans
    70. Qureshi H, Sharafkhaneh A, Hanania NA. Chronic obstructive pulmonary disease exacerbations: latest evidence and clinical implications. Ther Adv Chronic Dis. 2014 Sep; 5(5):212-27. PMID: 25177479; PMCID: PMC4131503.
      Citations: 49     
    71. Sharafkhaneh A, Altan AE, Colice GL, Hanania NA, Donohue JF, Kurlander JL, Rodriguez-Roisin R, Altman PR. A simple rule to identify patients with chronic obstructive pulmonary disease who may need treatment reevaluation. Respir Med. 2014 Sep; 108(9):1310-20. PMID: 25130680.
      Citations: 4     Fields:    Translation:Humans
    72. McGinnis K, Kleerup E, Wongtrakool C, Hoo GS, Kim J, Sharafkhaneh A, Huang L, Luo Z, Thompson B, Diaz P, Kirk GD, Rom W, Detels R, Kingsley L, Morris A, Crothers K. HIV infection is associated with reduced pulmonary diffusing capacity. J Acquir Immune Defic Syndr. 2013 Nov 01; 64(3):271-8. PMID: 23979001; PMCID: PMC3845879.
      Citations: 46     Fields:    Translation:Humans
    73. Sharafkhaneh A, Wolf RA, Goodnight S, Hanania NA, Make BJ, Tashkin DP. Perceptions and attitudes toward the use of nebulized therapy for COPD: patient and caregiver perspectives. COPD. 2013 Aug; 10(4):482-92. PMID: 23875742.
      Citations: 15     Fields:    Translation:Humans
    74. Sharafkhaneh A, Majid H, Gross NJ. Safety and tolerability of inhalational anticholinergics in COPD. Drug Healthc Patient Saf. 2013; 5:49-55. PMID: 23526112; PMCID: PMC3596125.
      Citations: 7     
    75. Fujimoto J, Kadara H, Garcia MM, Kabbout M, Behrens C, Liu DD, Lee JJ, Solis LM, Kim ES, Kalhor N, Moran C, Sharafkhaneh A, Lotan R, Wistuba II. G-protein coupled receptor family C, group 5, member A (GPRC5A) expression is decreased in the adjacent field and normal bronchial epithelia of patients with chronic obstructive pulmonary disease and non-small-cell lung cancer. J Thorac Oncol. 2012 Dec; 7(12):1747-1754. PMID: 23154545; PMCID: PMC3622592.
      Citations: 21     Fields:    Translation:Humans
    76. Al-shair K, Muellerova H, Yorke J, Rennard SI, Wouters EF, Hanania NA, Sharafkhaneh A, ECLIPSE investigators, Vestbo J. Examining fatigue in COPD: development, validity and reliability of a modified version of FACIT-F scale. Health Qual Life Outcomes. 2012 Aug 23; 10:100. PMID: 22913289; PMCID: PMC3491053.
      Citations: 12     Fields:    Translation:Humans
    77. Fan VS, Gaziano JM, Lew R, Bourbeau J, Adams SG, Leatherman S, Thwin SS, Huang GD, Robbins R, Sriram PS, Sharafkhaneh A, Mador MJ, Sarosi G, Panos RJ, Rastogi P, Wagner TH, Mazzuca SA, Shannon C, Colling C, Liang MH, Stoller JK, Fiore L, Niewoehner DE. A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations: a randomized, controlled trial. Ann Intern Med. 2012 May 15; 156(10):673-83. PMID: 22586006.
      Citations: 117     Fields:    Translation:Humans
    78. COPDGene CT Workshop Group, Barr RG, Berkowitz EA, Bigazzi F, Bode F, Bon J, Bowler RP, Chiles C, Crapo JD, Criner GJ, Curtis JL, Dass C, Dirksen A, Dransfield MT, Edula G, Erikkson L, Friedlander A, Galperin-Aizenberg M, Gefter WB, Gierada DS, Grenier PA, Goldin J, Han MK, Hanania NA, Hansel NN, Jacobson FL, Kauczor HU, Kinnula VL, Lipson DA, Lynch DA, MacNee W, Make BJ, Mamary AJ, Mann H, Marchetti N, Mascalchi M, McLennan G, Murphy JR, Naidich D, Nath H, Newell JD, Pistolesi M, Regan EA, Reilly JJ, Sandhaus R, Schroeder JD, Sciurba F, Shaker S, Sharafkhaneh A, Silverman EK, Steiner RM, Strange C, Sverzellati N, Tashjian JH, van Beek EJ, Washington L, Washko GR, Westney G, Wood SA, Woodruff PG. A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation. COPD. 2012 Apr; 9(2):151-9. PMID: 22429093; PMCID: PMC3752926.
      Citations: 73     Fields:    Translation:Humans
    79. Sharafkhaneh A, Southard JG, Goldman M, Uryniak T, Martin UJ. Effect of budesonide/formoterol pMDI on COPD exacerbations: a double-blind, randomized study. Respir Med. 2012 Feb; 106(2):257-68. PMID: 22033040.
      Citations: 63     Fields:    Translation:Humans
    80. Garcia JM, Sharafkhaneh H, Hirshkowitz M, Elkhatib R, Sharafkhaneh A. Weight and metabolic effects of CPAP in obstructive sleep apnea patients with obesity. Respir Res. 2011 Jun 15; 12(1):80. PMID: 21676224; PMCID: PMC3146428.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    81. Hanania NA, Sharafkhaneh A, Celli B, Decramer M, Lystig T, Kesten S, Tashkin D. Acute bronchodilator responsiveness and health outcomes in COPD patients in the UPLIFT trial. Respir Res. 2011 Jan 11; 12:6. PMID: 21219660; PMCID: PMC3027109.
      Citations: 18     Fields:    Translation:Humans
    82. McCurdy MR, Sharafkhaneh A, Abdel-Monem H, Rojo J, Tittel FK. Exhaled nitric oxide parameters and functional capacity in chronic obstructive pulmonary disease. J Breath Res. 2011 Mar; 5(1):016003. PMID: 21378438.
      Citations: 5     Fields:    Translation:Humans
    83. Hirshkowitz M, Sharafkhaneh A. Sleep and genitourinary systems: physiology and disorders. Handb Clin Neurol. 2011; 98:355-62. PMID: 21056197.
      Citations:    Fields:    Translation:Humans
    84. Hirshkowitz M, Sharafkhaneh A. Normal sleep-recording and scoring techniques. Handb Clin Neurol. 2011; 98:29-43. PMID: 21056177.
      Citations:    Fields:    Translation:Humans
    85. Hanania NA, Sharma G, Sharafkhaneh A. COPD in the elderly patient. Semin Respir Crit Care Med. 2010 Oct; 31(5):596-606. PMID: 20941660.
      Citations: 19     Fields:    Translation:Humans
    86. Sharafkhaneh A, Mattewal AS, Abraham VM, Dronavalli G, Hanania NA. Budesonide/formoterol combination in COPD: a US perspective. Int J Chron Obstruct Pulmon Dis. 2010 Oct 05; 5:357-66. PMID: 21037960; PMCID: PMC2962302.
      Citations: 13     Fields:    Translation:HumansAnimals
    87. Hanania NA, Locantore NW, Watkins ML, Wouters EF, Rennard SI, Sharafkhaneh A, Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study investi, M?llerova H, Vestbo J. Determinants of depression in the ECLIPSE chronic obstructive pulmonary disease cohort. Am J Respir Crit Care Med. 2011 Mar 01; 183(5):604-11. PMID: 20889909.
      Citations: 90     Fields:    Translation:Humans
    88. Sharafkhaneh A, Petersen NJ, Yu HJ, Dalal AA, Johnson ML, Hanania NA. Burden of COPD in a government health care system: a retrospective observational study using data from the US Veterans Affairs population. Int J Chron Obstruct Pulmon Dis. 2010 May 06; 5:125-32. PMID: 20461144; PMCID: PMC2866562.
      Citations: 20     Fields:    Translation:Humans
    89. Kumar S, Sharafkhaneh A, Edmonds J, Schultz R, Hopkins B. Treatment of vns-induced laryngospasm with botulinum toxin. Neurology. 2009 Nov 24; 73(21):1808-10. PMID: 19933985.
      Citations: 1     Fields:    Translation:Humans
    90. Sharafkhaneh A, Jayaraman G, Kaleekal T, Sharafkhaneh H, Hirshkowitz M. Sleep disorders and their management in patients with COPD. Ther Adv Respir Dis. 2009 Dec; 3(6):309-18. PMID: 19880428.
      Citations: 3     Fields:    Translation:Humans
    91. Niewoehner DE, Lapidus R, Cote C, Sharafkhaneh A, Plautz M, Johnson P, Kesten S. Therapeutic conversion of the combination of ipratropium and albuterol to tiotropium in patients with chronic obstructive pulmonary disease. Pulm Pharmacol Ther. 2009 Dec; 22(6):587-92. PMID: 19737620.
      Citations: 3     Fields:    Translation:Humans
    92. Bailey WC, Sciurba FC, Hanania NA, Donohue JF, Ferguson GT, Zibrak JD, Sharafkhaneh A, Marcus P, Rosa K, Piault EC, Martinez FJ. Development and validation of the Chronic Obstructive Pulmonary Disease Assessment Questionnaire (COPD-AQ). Prim Care Respir J. 2009 Sep; 18(3):198-207. PMID: 19492178; PMCID: PMC6619264.
      Citations: 5     Fields:    Translation:Humans
    93. Jayaraman G, Sharafkhaneh H, Hirshkowitz M, Sharafkhaneh A. Pharmacotherapy of obstructive sleep apnea. Ther Adv Respir Dis. 2008 Dec; 2(6):375-86. PMID: 19124383.
      Citations: 3     Fields:    Translation:Humans
    94. Cote C, Pearle JL, Sharafkhaneh A, Spangenthal S. Faster onset of action of formoterol versus salmeterol in patients with chronic obstructive pulmonary disease: a multicenter, randomized study. Pulm Pharmacol Ther. 2009 Feb; 22(1):44-9. PMID: 19071226.
      Citations: 10     Fields:    Translation:Humans
    95. Washko GR, Criner GJ, Mohsenifar Z, Sciurba FC, Sharafkhaneh A, Make BJ, Hoffman EA, Reilly JJ. Computed tomographic-based quantification of emphysema and correlation to pulmonary function and mechanics. COPD. 2008 Jun; 5(3):177-86. PMID: 18568842.
      Citations: 40     Fields:    Translation:Humans
    96. Sharafkhaneh A, Hanania NA, Kim V. Pathogenesis of emphysema: from the bench to the bedside. Proc Am Thorac Soc. 2008 May 01; 5(4):475-7. PMID: 18453358; PMCID: PMC2645322.
      Citations: 73     Fields:    Translation:HumansAnimals
    97. Kim V, Benditt JO, Wise RA, Sharafkhaneh A. Oxygen therapy in chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2008 May 01; 5(4):513-8. PMID: 18453364; PMCID: PMC2645328.
      Citations: 43     Fields:    Translation:Humans
    98. Fessler HE, Scharf SM, Ingenito EP, McKenna RJ, Sharafkhaneh A. Physiologic basis for improved pulmonary function after lung volume reduction. Proc Am Thorac Soc. 2008 May 01; 5(4):416-20. PMID: 18453348; PMCID: PMC2645312.
      Citations: 17     Fields:    Translation:Humans
    99. Sharafkhaneh A, Falk JA, Minai OA, Lipson DA. Overview of the perioperative management of lung volume reduction surgery patients. Proc Am Thorac Soc. 2008 May 01; 5(4):438-41. PMID: 18453352; PMCID: PMC2645316.
      Citations: 9     Fields:    Translation:Humans
    100. Criner GJ, Sharafkhaneh A, Player R, Conoscenti CS, Johnson P, Keyser MT, Cassino C. Efficacy of tiotropium inhalation powder in african-american patients with chronic obstructive pulmonary disease. COPD. 2008 Feb; 5(1):35-41. PMID: 18259973.
      Citations: 10     Fields:    Translation:Humans
    101. Sharafkhaneh A, Velamuri S, Badmaev V, Lan C, Hanania N. The potential role of natural agents in treatment of airway inflammation. Ther Adv Respir Dis. 2007 Dec; 1(2):105-20. PMID: 19124352.
      Citations: 12     Fields:    Translation:HumansAnimals
    102. Kunik ME, Veazey C, Cully JA, Souchek J, Graham DP, Hopko D, Carter R, Sharafkhaneh A, Goepfert EJ, Wray N, Stanley MA. COPD education and cognitive behavioral therapy group treatment for clinically significant symptoms of depression and anxiety in COPD patients: a randomized controlled trial. Psychol Med. 2008 Mar; 38(3):385-96. PMID: 17922939.
      Citations: 57     Fields:    Translation:Humans
    103. Hanania NA, Sharafkhaneh A. Update on the pharmacologic therapy for chronic obstructive pulmonary disease. Clin Chest Med. 2007 Sep; 28(3):589-607, vi-vii. PMID: 17720046.
      Citations: 2     Fields:    Translation:Humans
    104. Xu Y, Jagannath C, Liu XD, Sharafkhaneh A, Kolodziejska KE, Eissa NT. Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity. 2007 Jul; 27(1):135-44. PMID: 17658277; PMCID: PMC2680670.
      Citations: 410     Fields:    Translation:HumansAnimalsCells
    105. Hogg JC, Chu FS, Tan WC, Sin DD, Patel SA, Pare PD, Martinez FJ, Rogers RM, Make BJ, Criner GJ, Cherniack RM, Sharafkhaneh A, Luketich JD, Coxson HO, Elliott WM, Sciurba FC. Survival after lung volume reduction in chronic obstructive pulmonary disease: insights from small airway pathology. Am J Respir Crit Care Med. 2007 Sep 01; 176(5):454-9. PMID: 17556723; PMCID: PMC1976540.
      Citations: 64     Fields:    Translation:Humans
    106. Niewoehner DE, Lokhnygina Y, Rice K, Kuschner WG, Sharafkhaneh A, Sarosi GA, Krumpe P, Pieper K, Kesten S. Risk indexes for exacerbations and hospitalizations due to COPD. Chest. 2007 Jan; 131(1):20-8. PMID: 17218552.
      Citations: 63     Fields:    Translation:Humans
    107. Sharafkhaneh A, Sharafkhaneh H, Bredikus A, Guilleminault C, Bozkurt B, Hirshkowitz M. Effect of atrial overdrive pacing on obstructive sleep apnea in patients with systolic heart failure. Sleep Med. 2007 Jan; 8(1):31-6. PMID: 17157066.
      Citations: 14     Fields:    Translation:HumansPHPublic Health
    108. Sharafkhaneh A, Babb TG, Officer TM, Hanania NA, Sharafkhaneh H, Boriek AM. The confounding effects of thoracic gas compression on measurement of acute bronchodilator response. Am J Respir Crit Care Med. 2007 Feb 15; 175(4):330-5. PMID: 17110648; PMCID: PMC1899266.
      Citations: 6     Fields:    Translation:Humans
    109. Hanania NA, Moore RH, Zimmerman JL, Miller CT, Bag R, Sharafkhaneh A, Dickey BF. The role of intrinsic efficacy in determining response to a beta2-agonist in acute severe asthma. Respir Med. 2007 May; 101(5):1007-14. PMID: 17052901.
      Citations: 7     Fields:    Translation:Humans
    110. Sciurba FC, Martinez FJ, Rogers RM, Make BJ, Criner GJ, Cherniack RM, Patel SA, Chu F, Coxson HO, Sharafkhaneh A, Elliot M, Luketich JD, Hogg JC. Relationship between pathologic characteristics of peripheral airways and outcome after lung volume reduction surgery in severe chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2006 Aug; 3(6):533-4. PMID: 16921138; PMCID: PMC2647645.
      Citations: 4     Fields:    Translation:Humans
    111. Cully JA, Graham DP, Stanley MA, Ferguson CJ, Sharafkhaneh A, Souchek J, Kunik ME. Quality of life in patients with chronic obstructive pulmonary disease and comorbid anxiety or depression. Psychosomatics. 2006 Jul-Aug; 47(4):312-9. PMID: 16844889.
      Citations: 67     Fields:    Translation:Humans
    112. Williams OW, Sharafkhaneh A, Kim V, Dickey BF, Evans CM. Airway mucus: From production to secretion. Am J Respir Cell Mol Biol. 2006 May; 34(5):527-36. PMID: 16415249; PMCID: PMC2644218.
      Citations: 100     Fields:    Translation:HumansAnimalsCells
    113. Hirshkowitz M, Sharafkhaneh A. Clinical and technologic approaches to sleep evaluation. Neurol Clin. 2005 Nov; 23(4):991-1005, v-vi. PMID: 16243612.
      Citations:    Fields:    Translation:Humans
    114. Sharafkhaneh A, Giray N, Richardson P, Young T, Hirshkowitz M. Association of psychiatric disorders and sleep apnea in a large cohort. Sleep. 2005 Nov; 28(11):1405-11. PMID: 16335330.
      Citations: 132     Fields:    Translation:Humans
    115. Sharafkhaneh A, Goodnight-White S, Officer TM, Rodarte JR, Boriek AM. Altered thoracic gas compression contributes to improvement in spirometry with lung volume reduction surgery. Thorax. 2005 Apr; 60(4):288-92. PMID: 15790983; PMCID: PMC1747381.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    116. Hirshkowitz M, Sharafkhaneh A. Positive airway pressure therapy of OSA. Semin Respir Crit Care Med. 2005 Feb; 26(1):68-79. PMID: 16052419.
      Citations: 7     Fields:    Translation:Humans
    117. Hirshkowitz M, Sharafkhaneh A. On measurement consistency and other hobgoblins. Sleep. 2004 Aug 01; 27(5):847-8. PMID: 15453541.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    118. Sharafkhaneh A, Richardson P, Hirshkowitz M. Sleep apnea in a high risk population: a study of Veterans Health Administration beneficiaries. Sleep Med. 2004 Jul; 5(4):345-50. PMID: 15222990.
      Citations: 21     Fields:    Translation:Humans
    119. Sharafkhaneh A, Officer TM, Goodnight-White S, Rodarte JR, Boriek AM. Novel method for measuring effects of gas compression on expiratory flow. Am J Physiol Regul Integr Comp Physiol. 2004 Aug; 287(2):R479-84. PMID: 15117729.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    120. Sharafkhaneh A, Baaklini W, Gorin AB, Green L. Yield of transbronchial needle aspiration in diagnosis of mediastinal lesions. Chest. 2003 Dec; 124(6):2131-5. PMID: 14665491.
      Citations: 16     Fields:    Translation:Humans
    121. Sharafkhaneh A, Hirshkowitz M. Contextual factors and perceived self-reported sleepiness: a preliminary report. Sleep Med. 2003 Jul; 4(4):327-31. PMID: 14592305.
      Citations: 5     Fields:    Translation:Humans
    122. Hanania NA, Sharafkhaneh A, Barber R, Dickey BF. Beta-agonist intrinsic efficacy: measurement and clinical significance. Am J Respir Crit Care Med. 2002 May 15; 165(10):1353-8. PMID: 12016095.
      Citations: 25     Fields:    Translation:HumansAnimals
    123. Hirshkowitz M, Sharafkhaneh A. Sleep tools. Chest. 2001 May; 119(5):1303. PMID: 11348932.
      Citations:    Fields:    Translation:Humans
    124. Friedman HS, Wattanasuwan N, Sharafkhaneh A, Win M, Mallipeddi D, Khan IA, Dai CP. The comparative effects of drive and test stimulus intensity on myocardial excitability and vulnerability. Pacing Clin Electrophysiol. 2000 Jan; 23(1):84-95. PMID: 10666757.
      Citations:    Fields:    Translation:Animals
    125. Friedman HS, Rodney E, Sinha B, Sharafkhaneh A, Wattanasuwan N, Win M, Mallipeddi D, Sinha A, Hussain A, Dai CP. Verapamil prolongs atrial fibrillation by evoking an intense sympathetic neurohumoral effect. J Investig Med. 1999 Jul; 47(6):293-303. PMID: 10431484.
      Citations: 1     Fields:    Translation:Animals
    126. Friedman HS, Sinha B, Tun A, Pasha R, Sharafkhaneh A, Bharadwaj A. Zones of atrial vulnerability. Relationships to basic cycle length. Circulation. 1996 Sep 15; 94(6):1456-64. PMID: 8823006.
      Citations: 1     Fields:    Translation:Animals
    SHARAFKHANEH's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (412)
    Explore
    _
    Co-Authors (51)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _