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Institute for Clinical and Translational Research

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NORMAN SUSSMAN

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
DivisionMedicine-Gastroenterology & Hepatol
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Surgery
    DivisionSurgery-Transplant Division


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    Dr. Norman L. Sussman is leading an effort to improve medical resources in rural and underserved communities in Texas using a videoconference outreach model. He is also continuing to refine methods of assessing risk in patient with acute liver failure.

    Dr. Sussman is an active member of the Baylor - St. Luke’s Liver Center. He is Board Certified in Internal Medicine, Gastroenterology, and Transplant Hepatology. His clinical interests cover all aspects of liver disease, and his research interests include assessment and management of acute liver failure, artificial liver support, new agents to treat viral hepatitis, and complications of advanced cirrhosis.

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    R29DK039552     (SUSSMAN, NORMAN L)Jan 1, 1989 - Dec 31, 1993
    NIH/NIDDK
    BIOSYNTHESIS OF LIVER ALKALINE PHOSPHATASE
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Darr U, Sussman NL. Drug-Induced Liver Injury in the Setting of Analgesic Use. Clin Liver Dis. 2020 Feb; 24(1):121-129. PMID: 31753245.
      View in: PubMed
    2. DuBrock HM, Salgia RJ, Sussman NL, Bartolome SD, Kadry Z, Mulligan DC, Jenkins S, Lackore K, Channick RN, Kawut SM, Krowka MJ. Portopulmonary Hypertension: A Survey of Practice Patterns and Provider Attitudes. Transplant Direct. 2019 Jun; 5(6):e456. PMID: 31321292.
      View in: PubMed
    3. Shiffman ML, Sussman NL, Ravendhran N, Ditmyer M, Kowdley KV, Kugelmas M. Financial Compensation For Hepatologists in Different Practice Settings. Hepatology. 2019 06; 69(6):2664-2671. PMID: 30586171.
      View in: PubMed
    4. Sussman NL, Lucey MR. Alcohol and Alcoholic Liver Disease. Clin Liver Dis. 2019 02; 23(1):xiii-xiv. PMID: 30454837.
      View in: PubMed
    5. Villarreal JA, Sussman NL. Extracorporeal Liver Support in Patients with Acute Liver Failure. Tex Heart Inst J. 2019 02; 46(1):67-68. PMID: 30833847.
      View in: PubMed
    6. Rana A, Ackah RL, Webb GJ, Halazun KJ, Vierling JM, Liu H, Wu MF, Yoeli D, Kueht M, Mindikoglu AL, Sussman NL, Galván NT, Cotton RT, O'Mahony CA, Goss JA. No Gains in Long-term Survival After Liver Transplantation Over the Past Three Decades. Ann Surg. 2019 01; 269(1):20-27. PMID: 29303806.
      View in: PubMed
    7. Chhatwal J, Sussman NL. Universal Screening for Hepatitis C: An Important Step in Virus Elimination. Clin Gastroenterol Hepatol. 2019 04; 17(5):835-837. PMID: 30528843.
      View in: PubMed
    8. Khaderi S, Sussman N, Kanwal F. Project ECHO: The Specialist Will See You Now. Hepatology. 2018 12; 68(6):2066-2068. PMID: 30033576.
      View in: PubMed
    9. Grome L, Jalalabadi F, Fordis CM, Sussman NL, Reece EM. Bootstrapping Your Telehealth Program. Semin Plast Surg. 2018 Nov; 32(4):162-165. PMID: 30357035.
      View in: PubMed
    10. Jalalabadi F, Shultz KP, Sussman NL, Fisher WE, Reece EM. Initiating Telehealth in a Complex Organization. Semin Plast Surg. 2018 Nov; 32(4):159-161. PMID: 30357052.
      View in: PubMed
    11. Rana A, Sigireddi RR, Halazun KJ, Kothare A, Wu MF, Liu H, Kueht ML, Vierling JM, Sussman NL, Mindikoglu AL, Miloh T, Galvan NTN, Cotton RT, O'Mahony CA, Goss JA. Predicting Liver Allograft Discard: The Discard Risk Index. Transplantation. 2018 09; 102(9):1520-1529. PMID: 29485514.
      View in: PubMed
    12. Ganger DR, Rule J, Rakela J, Bass N, Reuben A, Stravitz RT, Sussman N, Larson AM, James L, Chiu C, Lee WM. Acute Liver Failure of Indeterminate Etiology: A Comprehensive Systematic Approach by An Expert Committee to Establish Causality. Am J Gastroenterol. 2018 09; 113(9):1319. PMID: 29946176.
      View in: PubMed
    13. Sussman NL, Kelly JH. Extracorporeal cellular therapy (ELAD) in severe alcoholic hepatitis: A multinational, prospective, controlled, randomized trial. Liver Transpl. 2018 05; 24(5):711. PMID: 29385313.
      View in: PubMed
    14. Rana A, Witte ED, Halazun KJ, Sood GK, Mindikoglu AL, Sussman NL, Vierling JM, Kueht ML, Galvan NTN, Cotton RT, O'Mahony CA, Goss JA. Liver transplant length of stay (LOS) index: A novel predictive score for hospital length of stay following liver transplantation. Clin Transplant. 2017 Dec; 31(12). PMID: 29044759.
      View in: PubMed
    15. DuBrock HM, Goldberg DS, Sussman NL, Bartolome SD, Kadry Z, Salgia RJ, Mulligan DC, Kremers WK, Kawut SM, Krowka MJ, Channick RN. Predictors of Waitlist Mortality in Portopulmonary Hypertension. Transplantation. 2017 07; 101(7):1609-1615. PMID: 28207639.
      View in: PubMed
    16. Goss M, Reese J, Kueht M, Vierling JM, Mindikoglu AL, Sussman NL, Kaplan B, Wood RP, Rana AA. A Surge in cadaveric liver donors and a national narcotic epidemic: Is there an association? Liver Transpl. 2017 05; 23(5):698-700. PMID: 28295986.
      View in: PubMed
    17. Sussman NL, Remien CH. The Headache of Acetaminophen Overdose: Getting the NAC. Clin Gastroenterol Hepatol. 2017 04; 15(4):563-564. PMID: 28017841.
      View in: PubMed
    18. Thornton K, Deming P, Manch RA, Moore A, Kohli A, Gish R, Sussman NL, Khaderi S, Scott J, Mera J, Box T, Qualls C, Sedillo M, Arora S. Is response guided therapy dead? Low cure rates in patients with detectable hepatitis C virus at week 4 of treatment. Hepatol Int. 2016 Jul; 10(4):624-31. PMID: 27098355.
      View in: PubMed
    19. Carrion AF, Khaderi SA, Sussman NL. Model for end-stage liver disease limbo, model for end-stage liver disease purgatory, and the dilemma of treating hepatitis C in patients awaiting liver transplantation. Liver Transpl. 2016 Mar; 22(3):279-80. PMID: 26663608.
      View in: PubMed
    20. Sussman NL. Treatment of Overt Hepatic Encephalopathy. Clin Liver Dis. 2015 Aug; 19(3):551-63. PMID: 26195208.
      View in: PubMed
    21. Khaderi SA, Sussman NL. Screening for malignancy in primary sclerosing cholangitis (PSC). Curr Gastroenterol Rep. 2015 Apr; 17(4):17. PMID: 25786901.
      View in: PubMed
    22. Sussman NL, Kelly JH. Artificial liver. Clin Gastroenterol Hepatol. 2014 Sep; 12(9):1439-42. PMID: 24909908.
      View in: PubMed
    23. Khaderi S, Khan R, Safdar Z, Stribling R, Vierling JM, Goss JA, Sussman NL. Long-term follow-up of portopulmonary hypertension patients after liver transplantation. Liver Transpl. 2014 Jun; 20(6):724-7. PMID: 24648168.
      View in: PubMed
    24. Sussman NL, Remien CH, Kanwal F. The end of hepatitis C. Clin Gastroenterol Hepatol. 2014 Apr; 12(4):533-6. PMID: 24480676.
      View in: PubMed
    25. Remien CH, Sussman NL, Adler FR. Mathematical modelling of chronic acetaminophen metabolism and liver injury. Math Med Biol. 2014 Sep; 31(3):302-17. PMID: 23788256.
      View in: PubMed
    26. Ganeshan DM, Salem U, Viswanathan C, Balachandran A, Garg N, Silverman P, Bhosale P. Complications of oncologic therapy in the abdomen and pelvis: a review. Abdom Imaging. 2013 Feb; 38(1):1-21. PMID: 22806412.
      View in: PubMed
    27. Safdar Z, Bartolome S, Sussman N. Portopulmonary hypertension: an update. Liver Transpl. 2012 Aug; 18(8):881-91. PMID: 22674534.
      View in: PubMed
    28. Remien CH, Adler FR, Waddoups L, Box TD, Sussman NL. Mathematical modeling of liver injury and dysfunction after acetaminophen overdose: early discrimination between survival and death. Hepatology. 2012 Aug; 56(2):727-34. PMID: 22331703.
      View in: PubMed
    29. Sussman NL, Kochar R, Fallon MB. Pulmonary complications in cirrhosis. Curr Opin Organ Transplant. 2011 Jun; 16(3):281-8. PMID: 21543981.
      View in: PubMed
    30. Salek J, Byrne J, Box T, Longo N, Sussman N. Recurrent liver failure in a 25-year-old female. Liver Transpl. 2010 Sep; 16(9):1049-53. PMID: 20818742.
      View in: PubMed
    31. Sussman NL, McGuire BM, Kelly JH. Hepatic assist devices: will they ever be successful? Curr Gastroenterol Rep. 2009 Feb; 11(1):64-8. PMID: 19166661.
      View in: PubMed
    32. Sussman NL, Lee PL, Dries AM, Schwartz MR, Barton JC. Multi-organ iron overload in an African-American man with ALAS2 R452S and SLC40A1 R561G. Acta Haematol. 2008; 120(3):168-73. PMID: 19066423.
      View in: PubMed
    33. Sussman N. Interpreting antidepressant clinical trials. Ann Clin Psychiatry. 2007 Oct-Dec; 19(4):215-20. PMID: 18058279.
      View in: PubMed
    34. Agha A, Sussman N. Acute hepatic dysfunction with abdominal pain and ascites. MedGenMed. 2007 May 09; 9(2):31. PMID: 17955086.
      View in: PubMed
    35. Sussman N. Translating Science Into Service: Lessons Learned From the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Study. Prim Care Companion J Clin Psychiatry. 2007; 9(5):331-7. PMID: 17998951.
      View in: PubMed
    36. Sussman N, Kaza V, Barshes N, Stribling R, Goss J, O'Mahony C, Zhang E, Vierling J, Frost A. Successful liver transplantation following medical management of portopulmonary hypertension: a single-center series. Am J Transplant. 2006 Sep; 6(9):2177-82. PMID: 16796721.
      View in: PubMed
    37. Stribling R, Sussman N, Vierling JM. Treatment of hepatitis C infection. Gastroenterol Clin North Am. 2006 Jun; 35(2):463-86. PMID: 16880075.
      View in: PubMed
    38. Woofter A, Sussman N. Jaundice in a traveler returning from India. MedGenMed. 2006 Feb 16; 8(1):48. PMID: 16915178.
      View in: PubMed
    39. Clark RD, Wolohan PR, Hodgkin EE, Kelly JH, Sussman NL. Modelling in vitro hepatotoxicity using molecular interaction fields and SIMCA. J Mol Graph Model. 2004 Jul; 22(6):487-97. PMID: 15182808.
      View in: PubMed
    40. Sussman N. The implications of weight changes with antipsychotic treatment. J Clin Psychopharmacol. 2003 Jun; 23(3 Suppl 1):S21-6. PMID: 12832946.
      View in: PubMed
    41. Dunner DL, Laird LK, Zajecka J, Bailey L, Sussman N, Seabolt JL. Six-year perspectives on the safety and tolerability of nefazodone. J Clin Psychiatry. 2002; 63 Suppl 1:32-41. PMID: 11890563.
      View in: PubMed
    42. Kelly JH, Sussman NL. A fluorescent cell-based assay for cytochrome P-450 isozyme 1A2 induction and inhibition. J Biomol Screen. 2000 Aug; 5(4):249-54. PMID: 10992045.
      View in: PubMed
    43. Castaneda R, Sussman N, Levy R, Trujillo M. A Treatment Algorithm for Attention Deficit Hyperactivity Disorder in Cocaine-Dependent Adults: A One-Year Private Practice Study with Long-Acting Stimulants, Fluoxetine, and Bupropion. Subst Abus. 1999 Mar; 20(1):59-71. PMID: 12511821.
      View in: PubMed
    44. Sussman N. Anxiolytic antidepressant augmentation. J Clin Psychiatry. 1998; 59 Suppl 5:42-8; discussion 49-50. PMID: 9635547.
      View in: PubMed
    45. Sussman NL, Kelly JH. Extracorporeal liver support: cell-based therapy for the failing liver. Am J Kidney Dis. 1997 Nov; 30(5 Suppl 4):S66-71. PMID: 9372981.
      View in: PubMed
    46. Ellis AJ, Hughes RD, Wendon JA, Dunne J, Langley PG, Kelly JH, Gislason GT, Sussman NL, Williams R. Pilot-controlled trial of the extracorporeal liver assist device in acute liver failure. Hepatology. 1996 Dec; 24(6):1446-51. PMID: 8938179.
      View in: PubMed
    47. Sussman NL, Kelly JH. Artificial liver support. Clin Invest Med. 1996 Oct; 19(5):393-9. PMID: 8889280.
      View in: PubMed
    48. Sussman NL, Lake JR. Treatment of hepatic failure--1996: current concepts and progress toward liver dialysis. Am J Kidney Dis. 1996 May; 27(5):605-21. PMID: 8629619.
      View in: PubMed
    49. Lake JR, Sussman NL. Determining prognosis in patients with fulminant hepatic failure: when you absolutely, positively have to know the answer. Hepatology. 1995 Mar; 21(3):879-82. PMID: 7875687.
      View in: PubMed
    50. Sussman NL, Finegold MJ, Barish JP, Kelly JH. A case of syncytial giant-cell hepatitis treated with an extracorporeal liver assist device. Am J Gastroenterol. 1994 Jul; 89(7):1077-82. PMID: 7517100.
      View in: PubMed
    51. Sussman NL, Gislason GT, Kelly JH. Extracorporeal liver support. Application to fulminant hepatic failure. J Clin Gastroenterol. 1994 Jun; 18(4):320-4. PMID: 8071519.
      View in: PubMed
    52. Sussman NL, Gislason GT, Conlin CA, Kelly JH. The Hepatix extracorporeal liver assist device: initial clinical experience. Artif Organs. 1994 May; 18(5):390-6. PMID: 8037614.
      View in: PubMed
    53. Gislason GT, Lobdell DD, Kelly JH, Sussman NL. A treatment system for implementing an extracorporeal liver assist device. Artif Organs. 1994 May; 18(5):385-9. PMID: 8037613.
      View in: PubMed
    54. Kelly JH, Sussman NL. The hepatix extracorporeal liver assist device in the treatment of fulminant hepatic failure. ASAIO J. 1994 Jan-Mar; 40(1):83-5. PMID: 7514459.
      View in: PubMed
    55. Wood RP, Katz SM, Ozaki CF, Monsour HP, Gislason GT, Kelly JH, Sussman NL. Extracorporeal liver assist device (ELAD): a preliminary report. Transplant Proc. 1993 Aug; 25(4 Suppl 3):53-4. PMID: 8351720.
      View in: PubMed
    56. Sussman NL, Kelly JH. Artificial liver: a forthcoming attraction. Hepatology. 1993 Jun; 17(6):1163-4. PMID: 8514267.
      View in: PubMed
    57. Sussman NL, Kelly JH. Improved liver function following treatment with an extracorporeal liver assist device. Artif Organs. 1993 Jan; 17(1):27-30. PMID: 8422230.
      View in: PubMed
    58. Sussman NL, Kelly JH. Liver assist devices (LADs) will not be used to treat fulminant hepatic failure (FHF), but its consequences, namely hepatic encephalopathy (HE) Artif Organs. 1993 Jan; 17(1):43-5. PMID: 8422234.
      View in: PubMed
    59. Sussman NL, Kelly JH. Extracorporeal liver assist in the treatment of fulminant hepatic failure. Blood Purif. 1993; 11(3):170-4. PMID: 8280439.
      View in: PubMed
    60. Kelly JH, Koussayer T, He D, Chong MG, Shang TA, Whisennand HH, Sussman NL. Assessment of an extracorporeal liver assist device in anhepatic dogs. Artif Organs. 1992 Aug; 16(4):418-22. PMID: 10078286.
      View in: PubMed
    61. Sussman NL, Chong MG, Koussayer T, He DE, Shang TA, Whisennand HH, Kelly JH. Reversal of fulminant hepatic failure using an extracorporeal liver assist device. Hepatology. 1992 Jul; 16(1):60-5. PMID: 1618484.
      View in: PubMed
    62. Kelly JH, Koussayer T, He DE, Chong MG, Shang TA, Whisennand HH, Sussman NL. An improved model of acetaminophen-induced fulminant hepatic failure in dogs. Hepatology. 1992 Feb; 15(2):329-35. PMID: 1735538.
      View in: PubMed
    63. Ballenger JC, McDonald S, Noyes R, Rickels K, Sussman N, Woods S, Patin J, Singer J. The first double-blind, placebo-controlled trial of a partial benzodiazepine agonist abecarnil (ZK 112-119) in generalized anxiety disorder. Psychopharmacol Bull. 1991; 27(2):171-9. PMID: 1681563.
      View in: PubMed
    64. Sussman NL, Eliakim R, Rubin D, Perlmutter DH, DeSchryver-Kecskemeti K, Alpers DH. Intestinal alkaline phosphatase is secreted bidirectionally from villous enterocytes. Am J Physiol. 1989 Jul; 257(1 Pt 1):G14-23. PMID: 2546440.
      View in: PubMed
    65. Go MF, Schonfeld G, Pfleger B, Cole TG, Sussman NL, Alpers DH. Regulation of intestinal and hepatic apoprotein synthesis after chronic fat and cholesterol feeding. J Clin Invest. 1988 May; 81(5):1615-20. PMID: 3130399.
      View in: PubMed
    66. Seetharam S, Sussman NL, Komoda T, Alpers DH. The mechanism of elevated alkaline phosphatase activity after bile duct ligation in the rat. Hepatology. 1986 May-Jun; 6(3):374-80. PMID: 3710426.
      View in: PubMed
    67. Sussman NL, Seetharam S, Blaufuss MC, Alpers DH. Translation of rat intestinal RNA yields two alkaline phosphatases. Biochem J. 1986 Mar 15; 234(3):563-8. PMID: 2424431.
      View in: PubMed
    68. SUSSMAN N. The autonomic nervous system in rheumatoid arthritis; a preliminary report on the use of D.H.E.-45. Med Times. 1952 Sep; 80(9):560-3. PMID: 12992244.
      View in: PubMed
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