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LISA BOMGAARS

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1102 BATES
Houston, TX 77030
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    Collapse Research 
    Collapse research activities and funding
    U54CA254569     (ALLEN, CARL E;JOLOBA, MOSES LUTAAKOME;SCHEURER, MICHAEL E)Jul 25, 2020 - Jun 30, 2025
    NIH
    Pediatric HIV/AIDS & Infection-Related Malignancies Research Consortium for sub-Saharan Africa (PARCA)
    Role: Co-Investigator
    UG1CA189955     (POLLOCK, BRAD H)Aug 1, 2014 - Jul 31, 2025
    NIH
    Children's Oncology Group NCI Community Oncology Research Program (NCORP) Research Base grant
    Role: Subaward PI
    U10CA180886     (HAWKINS, DOUGLAS S)Apr 11, 2014 - Feb 28, 2025
    NIH
    COG NCTN Network Group Operations Center
    Role: Subaward PI

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Albisetti M, Tartakovsky I, Halton J, Bomgaars L, Chalmers E, Mitchell LG, Luciani M, Nurmeev I, Gorbatikov K, Miede C, Brueckmann M, Brand?o LR, Study Investigators. Dabigatran for Treatment and Secondary Prevention of Venous Thromboembolism in Pediatric Congenital Heart Disease. J Am Heart Assoc. 2024 Feb 20; 13(4):e028957. PMID: 38348778.
      Citations:    Fields:    Translation:HumansPHPublic Health
    2. Tartakovsky I, Halton J, Bomgaars L, Chalmers E, Saracco P, Felgenhauer J, Lvova O, Simetzberger M, Sun Z, Mitchell LG, Brand?o LR, Albisetti M, Luciani M. Dabigatran in the treatment and secondary prophylaxis of venous thromboembolism in children with thrombophilia. Blood Adv. 2022 11 22; 6(22):5908-5923. PMID: 36150047; PMCID: PMC9661433.
      Citations:    
    3. Mitchell LG, Huang F, Bomgaars L, Chalmers E, Halton J, Joseph D, Tartakovsky I, Gropper S, Brueckmann M, R?shammar D, Albisetti M, Brand?o LR, Luciani M. Anticoagulant Effects of Dabigatran on Coagulation Laboratory Parameters in Pediatric Patients: Combined Data from Five Pediatric Clinical Trials. Thromb Haemost. 2022 Sep; 122(9):1573-1583. PMID: 35909257; PMCID: PMC9420551.
      Citations:    
    4. Collier AB, Krailo MD, Dang HM, DuBois SG, Hawkins DS, Bernstein ML, Bomgaars LR, Reed DR, Gorlick RG, Janeway KA. Outcome of patients with relapsed or progressive Ewing sarcoma enrolled on cooperative group phase 2 clinical trials: A report from the Children's Oncology Group. Pediatr Blood Cancer. 2021 12; 68(12):e29333. PMID: 34496122; PMCID: PMC8541905.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    5. Huang F, Bomgaars L, Chalmers E, Halton J, Mitchell LG, Bergstrand M, Ibrahim MMA, Joseph D, Tartakovsky I, Gropper S, Brueckmann M, R?shammar D, Albisetti M, Luciani M, Brand?o LR. Pharmacokinetic modeling and simulation support for age- and weight-adjusted dosing of dabigatran etexilate in children with venous thromboembolism. J Thromb Haemost. 2021 05; 19(5):1259-1270. PMID: 33636042; PMCID: PMC8251571.
      Citations:    Fields:    Translation:Humans
    6. Halton J, Bomgaars L, Chalmers E, Mitchell LG, Nurmeev I, Sharathkumar A, Svirin P, Gorbatikov K, Tartakovsky I, Simetzberger M, Huang F, Sun Z, Gropper S, Reilly P, Brueckmann M, Albisetti M, DIVERSITY Trial Investigators, Brand?o LR, Luciani M, Kreuzer J. Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial. Lancet Haematol. 2021 Jan; 8(1):e22-e33. PMID: 33290737.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    7. Halton J, Bomgaars L, Chalmers E, Mitchell LG, Nurmeev I, Svirin P, Kuhn T, Zapletal O, Tartakovsky I, Simetzberger M, Huang F, Sun Z, Gropper S, Brueckmann M, DIVERSITY Study Investigators, Brand?o LR, Albisetti M, Kreuzer J, Luciani M. Safety of dabigatran etexilate for the secondary prevention of venous thromboembolism in children. Blood. 2020 02 13; 135(7):491-504. PMID: 31805182; PMCID: PMC7019192.
      Citations: 14     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    8. Beechinor RJ, Thompson PA, Hwang MF, Vargo RC, Bomgaars LR, Gerhart JG, Dreyer ZE, Gonzalez D. The Population Pharmacokinetics of High-Dose Methotrexate in Infants with Acute Lymphoblastic Leukemia Highlight the Need for Bedside Individualized Dose Adjustment: A Report from the Children's Oncology Group. Clin Pharmacokinet. 2019 07; 58(7):899-910. PMID: 30810947; PMCID: PMC6658326.
      Citations: 7     Fields:    Translation:Humans
    9. Hawkins DS, Chi YY, Anderson JR, Tian J, Arndt CAS, Bomgaars L, Donaldson SS, Hayes-Jordan A, Mascarenhas L, McCarville MB, McCune JS, McCowage G, Million L, Morris CD, Parham DM, Rodeberg DA, Rudzinski ER, Shnorhavorian M, Spunt SL, Skapek SX, Teot LA, Wolden S, Yock TI, Meyer WH. Addition of Vincristine and Irinotecan to Vincristine, Dactinomycin, and Cyclophosphamide Does Not Improve Outcome for Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group. J Clin Oncol. 2018 09 20; 36(27):2770-2777. PMID: 30091945; PMCID: PMC6145831.
      Citations: 39     Fields:    Translation:HumansCTClinical Trials
    10. Biss B, Bomgaars L, Brueckmann M, Chalmers E, Gropper S, Halton JML, Harper R, Huang F, Manastirski I, Mitchell LG, Tartakovsky I, Wang B, Luciani M, Albisetti M, Brand?o LR. Phase 3, single-arm, multicenter study of dabigatran etexilate for secondary prevention of venous thromboembolism in children: Rationale and design. Res Pract Thromb Haemost. 2018 Jul; 2(3):580-590. PMID: 30046763; PMCID: PMC6046601.
      Citations: 1     
    11. Biss B, Bomgaars L, Brueckmann M, Chalmers E, Gropper S, Harper R, Huang F, Manastirski I, Mitchell LG, Tartakovsky I, Wang B, Halton JML, Albisetti M, Brand?o LR, Luciani M. Design and rationale for the DIVERSITY study: An open-label, randomized study of dabigatran etexilate for pediatric venous thromboembolism. Res Pract Thromb Haemost. 2018 Apr; 2(2):347-356. PMID: 30046738; PMCID: PMC6055566.
      Citations:    
    12. Halton JML, Biss B, Bomgaars L, Brueckmann M, Gropper S, Harper R, Huang F, Maas H, Tartakovsky I, Mitchell LG, Albisetti M, Luciani M. Phase IIa study of dabigatran etexilate in children with venous thrombosis: pharmacokinetics, safety, and tolerability. J Thromb Haemost. 2017 11; 15(11):2147-2157. PMID: 28921890.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    13. Bomgaars LR, Massicotte MP, Berlin Heart EXCOR Pediatric VAD IDE study investigators, Steiner ME. Antithrombotic Therapy in a Prospective Trial of a Pediatric Ventricular Assist Device. ASAIO J. 2016 Nov/Dec; 62(6):719-727. PMID: 27556152; PMCID: PMC5098459.
      Citations: 9     Fields:    Translation:Humans
    14. Lagmay JP, Krailo MD, Dang H, Kim A, Hawkins DS, Beaty O, Widemann BC, Zwerdling T, Bomgaars L, Langevin AM, Grier HE, Weigel B, Blaney SM, Gorlick R, Janeway KA. Outcome of Patients With Recurrent Osteosarcoma Enrolled in Seven Phase II Trials Through Children's Cancer Group, Pediatric Oncology Group, and Children's Oncology Group: Learning From the Past to Move Forward. J Clin Oncol. 2016 09 01; 34(25):3031-8. PMID: 27400942; PMCID: PMC5012712.
      Citations: 64     Fields:    Translation:HumansCTClinical Trials
    15. Manco-Johnson MJ, Bomgaars L, Palascak J, Shapiro A, Geil J, Fritsch S, Pavlova BG, Gelmont D. Efficacy and safety of protein C concentrate to treat purpura fulminans and thromboembolic events in severe congenital protein C deficiency. Thromb Haemost. 2016 07 04; 116(1):58-68. PMID: 27052576.
      Citations: 4     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    16. Bomgaars LR, Moffett BS. Response to warfarin therapy in obese pediatric patients dosed according to institutional guidelines. J Pediatr Hematol Oncol. 2014 Nov; 36(8):e487-9. PMID: 24458250.
      Citations:    Fields:    Translation:Humans
    17. Hundalani SG, Nguyen KT, Soundar E, Kostousov V, Bomgaars L, Moise A, Hui SK, Teruya J. Age-based difference in activation markers of coagulation and fibrinolysis in extracorporeal membrane oxygenation. Pediatr Crit Care Med. 2014 Jun; 15(5):e198-205. PMID: 24614609.
      Citations: 7     Fields:    Translation:Humans
    18. Cabrera AG, Teruya J, Bomgaars L, Moffett BS. Anticoagulation therapy trends in children supported by ventricular assist devices: a multi-institutional study. ASAIO J. 2014 Mar-Apr; 60(2):211-5. PMID: 24399058.
      Citations: 2     Fields:    Translation:Humans
    19. Moffett BS, Kim S, Bomgaars LR. Readmissions for warfarin-related bleeding in pediatric patients after hospital discharge. Pediatr Blood Cancer. 2013 Sep; 60(9):1503-6. PMID: 23606286.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    20. Richard AA, Kim S, Moffett BS, Bomgaars L, Mahoney D, Yee DL. Comparison of anti-Xa levels in obese and non-obese pediatric patients receiving treatment doses of enoxaparin. J Pediatr. 2013 Feb; 162(2):293-6. PMID: 22959138.
      Citations: 6     Fields:    Translation:Humans
    21. Fraser CD, Jaquiss RD, Rosenthal DN, Humpl T, Canter CE, Blackstone EH, Naftel DC, Ichord RN, Bomgaars L, Tweddell JS, Massicotte MP, Turrentine MW, Cohen GA, Devaney EJ, Pearce FB, Carberry KE, Kroslowitz R, Almond CS, Berlin Heart Study Investigators. Prospective trial of a pediatric ventricular assist device. N Engl J Med. 2012 Aug 09; 367(6):532-41. PMID: 22873533.
      Citations: 78     Fields:    Translation:HumansCTClinical Trials
    22. Moffett BS, Ung M, Bomgaars L. Risk factors for elevated INR values during warfarin therapy in hospitalized pediatric patients. Pediatr Blood Cancer. 2012 Jun; 58(6):941-4. PMID: 22069087.
      Citations: 6     Fields:    Translation:Humans
    23. Klaassen RJ, Mathias SD, Buchanan G, Bussel J, Deuson R, Young NL, Collier A, Bomgaars L, Blanchette V. Pilot study of the effect of romiplostim on child health-related quality of life (HRQoL) and parental burden in immune thrombocytopenia (ITP). Pediatr Blood Cancer. 2012 Mar; 58(3):395-8. PMID: 21910213.
      Citations: 13     Fields:    Translation:Humans
    24. Bussel JB, Buchanan GR, Nugent DJ, Gnarra DJ, Bomgaars LR, Blanchette VS, Wang YM, Nie K, Jun S. A randomized, double-blind study of romiplostim to determine its safety and efficacy in children with immune thrombocytopenia. Blood. 2011 Jul 07; 118(1):28-36. PMID: 21502541.
      Citations: 60     Fields:    Translation:Humans
    25. Bomgaars L, Carberry K, Fraser C, West A, Teruya J. Development of factor V and thrombin inhibitors in children following bovine thrombin exposure during cardiac surgery: a report of three cases. Congenit Heart Dis. 2010 May-Jun; 5(3):303-8. PMID: 20576051.
      Citations: 1     Fields:    Translation:HumansAnimals
    26. Raman VS, Mason KJ, Rodriguez LM, Hassan K, Yu X, Bomgaars L, Heptulla RA. The role of adjunctive exenatide therapy in pediatric type 1 diabetes. Diabetes Care. 2010 Jun; 33(6):1294-6. PMID: 20332358; PMCID: PMC2875441.
      Citations: 18     Fields:    Translation:Humans
    27. Thornburg CD, Jones E, Bomgaars L, Gage BF. Pediatric warfarin practice and pharmacogenetic testing. Thromb Res. 2010 Aug; 126(2):e144-6. PMID: 20097410.
      Citations: 2     Fields:    Translation:Humans
    28. Jeha S, Razzouk B, Rytting M, Rheingold S, Albano E, Kadota R, Luchtman-Jones L, Bomgaars L, Gaynon P, Goldman S, Ritchey K, Arceci R, Altman A, Stine K, Steinherz L, Steinherz P. Phase II study of clofarabine in pediatric patients with refractory or relapsed acute myeloid leukemia. J Clin Oncol. 2009 Sep 10; 27(26):4392-7. PMID: 19652076; PMCID: PMC2744276.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    29. Yogev R, Arguedas A, Rodriguez A, Spigarelli MG, Bomgaars L, Roberts M, Abrams B, Zhou W, Looby M, Kaiser G, Hamed K, S?ez-Llorens X, De Le?n Castrej?n T. Pharmacokinetics and safety of famciclovir in children with herpes simplex or varicella-zoster virus infection. Antimicrob Agents Chemother. 2009 May; 53(5):1912-20. PMID: 19273678; PMCID: PMC2681556.
      Citations: 5     Fields:    Translation:HumansCellsCTClinical Trials
    30. Thompson PA, Rosner GL, Matthay KK, Moore TB, Bomgaars LR, Ellis KJ, Renbarger J, Berg SL. Impact of body composition on pharmacokinetics of doxorubicin in children: a Glaser Pediatric Research Network study. Cancer Chemother Pharmacol. 2009 Jul; 64(2):243-51. PMID: 19020877.
      Citations: 36     Fields:    Translation:Humans
    31. Bomgaars L, Thompson P, Berg S, Serabe B, Aleksic A, Blaney S. Valacyclovir and acyclovir pharmacokinetics in immunocompromised children. Pediatr Blood Cancer. 2008 Oct; 51(4):504-8. PMID: 18561175; PMCID: PMC4063282.
      Citations: 9     Fields:    Translation:Humans
    32. Yee DL, Dinu BR, Sun CW, Edwards RM, Justino H, Teruya J, Bray PF, Bomgaars L. Low prevalence and assay discordance of "aspirin resistance" in children. Pediatr Blood Cancer. 2008 Jul; 51(1):86-92. PMID: 18253960.
      Citations: 2     Fields:    Translation:Humans
    33. Thompson PA, Gupta M, Rosner GL, Yu A, Barrett J, Bomgaars L, Bernstein ML, Blaney SM, Mondick J. Pharmacokinetics of irinotecan and its metabolites in pediatric cancer patients: a report from the children's oncology group. Cancer Chemother Pharmacol. 2008 Nov; 62(6):1027-37. PMID: 18278496.
      Citations: 8     Fields:    Translation:Humans
    34. Krull KR, Brouwers P, Jain N, Zhang L, Bomgaars L, Dreyer Z, Mahoney D, Bottomley S, Okcu MF. Folate pathway genetic polymorphisms are related to attention disorders in childhood leukemia survivors. J Pediatr. 2008 Jan; 152(1):101-5. PMID: 18154909.
      Citations: 41     Fields:    Translation:Humans
    35. Bomgaars LR, Bernstein M, Krailo M, Kadota R, Das S, Chen Z, Adamson PC, Blaney SM. Phase II trial of irinotecan in children with refractory solid tumors: a Children's Oncology Group Study. J Clin Oncol. 2007 Oct 10; 25(29):4622-7. PMID: 17925558.
      Citations: 50     Fields:    Translation:HumansCTClinical Trials
    36. Bernardi RJ, Bomgaars L, Fox E, Balis FM, Egorin MJ, Lagattuta TF, Aikin A, Whitcomb P, Renbarger J, Lieberman FS, Berg SL, Blaney SM. Phase I clinical trial of intrathecal gemcitabine in patients with neoplastic meningitis. Cancer Chemother Pharmacol. 2008 Jul; 62(2):355-61. PMID: 17909804.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    37. Horton TM, Pati D, Plon SE, Thompson PA, Bomgaars LR, Adamson PC, Ingle AM, Wright J, Brockman AH, Paton M, Blaney SM. A phase 1 study of the proteasome inhibitor bortezomib in pediatric patients with refractory leukemia: a Children's Oncology Group study. Clin Cancer Res. 2007 Mar 01; 13(5):1516-22. PMID: 17332297.
      Citations: 61     Fields:    Translation:HumansCTClinical Trials
    38. Blake MJ, Gaedigk A, Pearce RE, Bomgaars LR, Christensen ML, Stowe C, James LP, Wilson JT, Kearns GL, Leeder JS. Ontogeny of dextromethorphan O- and N-demethylation in the first year of life. Clin Pharmacol Ther. 2007 Apr; 81(4):510-6. PMID: 17301735.
      Citations: 47     Fields:    Translation:HumansCells
    39. Thompson PA, Murry DJ, Rosner GL, Lunagomez S, Blaney SM, Berg SL, Camitta BM, Dreyer ZE, Bomgaars LR. Methotrexate pharmacokinetics in infants with acute lymphoblastic leukemia. Cancer Chemother Pharmacol. 2007 May; 59(6):847-53. PMID: 17136402.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    40. Bomgaars LR, Megason GC, Pullen J, Langevin AM, Dale Weitman S, Hershon L, Kuhn JG, Bernstein M, Blaney SM. Phase I trial of irofulven (MGI 114) in pediatric patients with solid tumors. Pediatr Blood Cancer. 2006 Aug; 47(2):163-8. PMID: 16317728.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    41. Jeha S, Gaynon PS, Razzouk BI, Franklin J, Kadota R, Shen V, Luchtman-Jones L, Rytting M, Bomgaars LR, Rheingold S, Ritchey K, Albano E, Arceci RJ, Goldman S, Griffin T, Altman A, Gordon B, Steinherz L, Weitman S, Steinherz P. Phase II study of clofarabine in pediatric patients with refractory or relapsed acute lymphoblastic leukemia. J Clin Oncol. 2006 Apr 20; 24(12):1917-23. PMID: 16622268.
      Citations: 70     Fields:    Translation:HumansCTClinical Trials
    42. Gururangan S, Petros WP, Poussaint TY, Hancock ML, Phillips PC, Friedman HS, Bomgaars L, Blaney SM, Kun LE, Boyett JM. Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004). Clin Cancer Res. 2006 Mar 01; 12(5):1540-6. PMID: 16533779.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    43. Bomgaars L, Kerr J, Berg S, Kuttesch J, Klenke R, Blaney SM. A phase I study of irinotecan administered on a weekly schedule in pediatric patients. Pediatr Blood Cancer. 2006 Jan; 46(1):50-5. PMID: 15768380.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    44. Bomgaars L, McLeod HL. Pharmacogenetics and pediatric cancer. Cancer J. 2005 Jul-Aug; 11(4):314-23. PMID: 16197721.
      Citations: 1     Fields:    Translation:Humans
    45. Heptulla RA, Rodriguez LM, Bomgaars L, Haymond MW. The role of amylin and glucagon in the dampening of glycemic excursions in children with type 1 diabetes. Diabetes. 2005 Apr; 54(4):1100-7. PMID: 15793249.
      Citations: 18     Fields:    Translation:HumansCTClinical Trials
    46. Chintagumpala M, Blaney SM, Bomgaars LR, Aleksic A, Kuttesch JF, Klenke RA, Berg SL. Phase I and pharmacokinetic study of thalidomide with carboplatin in children with cancer. J Clin Oncol. 2004 Nov 01; 22(21):4394-400. PMID: 15514381.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    47. Bomgaars L, Geyer JR, Franklin J, Dahl G, Park J, Winick NJ, Klenke R, Berg SL, Blaney SM. Phase I trial of intrathecal liposomal cytarabine in children with neoplastic meningitis. J Clin Oncol. 2004 Oct 01; 22(19):3916-21. PMID: 15459213.
      Citations: 39     Fields:    Translation:HumansCTClinical Trials
    48. Lacayo NJ, Lum BL, Becton DL, Weinstein H, Ravindranath Y, Chang MN, Bomgaars L, Lauer SJ, Sikic BI, Dahl GV. Pharmacokinetic interactions of cyclosporine with etoposide and mitoxantrone in children with acute myeloid leukemia. Leukemia. 2002 May; 16(5):920-7. PMID: 11986955.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    49. Evans WE, Hon YY, Bomgaars L, Coutre S, Holdsworth M, Janco R, Kalwinsky D, Keller F, Khatib Z, Margolin J, Murray J, Quinn J, Ravindranath Y, Ritchey K, Roberts W, Rogers ZR, Schiff D, Steuber C, Tucci F, Kornegay N, Krynetski EY, Relling MV. Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. J Clin Oncol. 2001 Apr 15; 19(8):2293-301. PMID: 11304783.
      Citations: 94     Fields:    Translation:Humans
    50. Bomgaars L, Berg SL, Blaney SM. The development of camptothecin analogs in childhood cancers. Oncologist. 2001; 6(6):506-16. PMID: 11743213.
      Citations: 10     Fields:    Translation:Humans
    51. Bomgaars L, Gunawardena S, Kelley SE, Ramu A. The inactivation of doxorubicin by long ultraviolet light. Cancer Chemother Pharmacol. 1997; 40(6):506-12. PMID: 9332465.
      Citations: 3     Fields:    Translation:AnimalsCells
    52. Murray JC, Bomgaars LR, Carcamo B, Mahoney DH. Lymphoid malignancies following Kawasaki disease. Am J Hematol. 1995 Dec; 50(4):299-300. PMID: 7485107.
      Citations: 4     Fields:    Translation:Humans
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