"Carcinoma, Merkel Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)
| Descriptor ID |
D015266
|
| MeSH Number(s) |
C02.256.721.150 C02.928.216 C04.557.465.625.650.240.325 C04.557.470.200.025.370.325 C04.557.580.625.650.240.325
|
| Concept/Terms |
Carcinoma, Merkel Cell- Carcinoma, Merkel Cell
- Merkle Tumors
- Tumors, Merkle
- Merkel Cell Tumor
- Tumor, Merkel Cell
- Merkel Cell Cancer
- Cancer, Merkel Cell
- Cell Cancer, Merkel
- Merkel Cell Carcinoma
|
Below are MeSH descriptors whose meaning is more general than "Carcinoma, Merkel Cell".
- Diseases [C]
- Virus Diseases [C02]
- DNA Virus Infections [C02.256]
- Polyomavirus Infections [C02.256.721]
- Carcinoma, Merkel Cell [C02.256.721.150]
- Tumor Virus Infections [C02.928]
- Carcinoma, Merkel Cell [C02.928.216]
- Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
- Neoplasms, Germ Cell and Embryonal [C04.557.465]
- Neuroectodermal Tumors [C04.557.465.625]
- Neuroendocrine Tumors [C04.557.465.625.650]
- Carcinoma, Neuroendocrine [C04.557.465.625.650.240]
- Carcinoma, Merkel Cell [C04.557.465.625.650.240.325]
- Neoplasms, Glandular and Epithelial [C04.557.470]
- Carcinoma [C04.557.470.200]
- Adenocarcinoma [C04.557.470.200.025]
- Carcinoma, Neuroendocrine [C04.557.470.200.025.370]
- Carcinoma, Merkel Cell [C04.557.470.200.025.370.325]
- Neoplasms, Nerve Tissue [C04.557.580]
- Neuroectodermal Tumors [C04.557.580.625]
- Neuroendocrine Tumors [C04.557.580.625.650]
- Carcinoma, Neuroendocrine [C04.557.580.625.650.240]
- Carcinoma, Merkel Cell [C04.557.580.625.650.240.325]
Below are MeSH descriptors whose meaning is more specific than "Carcinoma, Merkel Cell".
This graph shows the total number of publications written about "Carcinoma, Merkel Cell" by people in this website by year, and whether "Carcinoma, Merkel Cell" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 3 | 0 | 3 |
| 2025 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Carcinoma, Merkel Cell" by people in Profiles.
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Genomic Signatures of Poor Prognosis in Merkel Cell Carcinoma: A Single-Institution Prospective Study. Mol Cancer Res. 2025 Nov 03; 23(11):923-935.
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Preexisting Skin-Resident CD8 and ?d T-cell Circuits Mediate Immune Response in Merkel Cell Carcinoma and Predict Immunotherapy Efficacy. Cancer Discov. 2024 Sep 04; 14(9):1631-1652.
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Inpatient prevalence and factors associated with Merkel Cell Carcinoma inpatient hospitalization in the United States. Arch Dermatol Res. 2024 Jul 27; 316(8):489.
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Non-cancer related causes of mortality in Merkel cell carcinoma: a national database study. Arch Dermatol Res. 2024 May 11; 316(5):168.
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Cytokeratin-20 negative nodal Merkel cell carcinoma with regressed primary: a potential pitfall in interpretation of nodal metastasis. Dermatol Online J. 2023 Jun 15; 29(3).
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Tumor infiltrating lymphocyte grade in Merkel cell carcinoma: relationships with clinical factors and independent prognostic value. Acta Oncol. 2020 Dec; 59(12):1409-1415.
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A Woman With a Large Ulcerated Nodule on the Finger. JAMA. 2018 Jan 02; 319(1):78-79.
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Viral oncoprotein antibodies as a marker for recurrence of Merkel cell carcinoma: A prospective validation study. Cancer. 2017 04 15; 123(8):1464-1474.
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Merkel cell carcinoma in a vein graft donor site. Cutis. 2016 May; 97(5):364-7.
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Lymphotropism of Merkel cell polyomavirus infection, Nova Scotia, Canada. Emerg Infect Dis. 2010 Nov; 16(11):1702-9.