"Killer Cells, Natural" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.
| Descriptor ID |
D007694
|
| MeSH Number(s) |
A11.118.637.555.567.537 A15.145.229.637.555.567.537 A15.382.490.555.567.537
|
| Concept/Terms |
Killer Cells, Natural- Killer Cells, Natural
- NK Cells
- Cell, NK
- Cells, NK
- NK Cell
- Natural Killer Cells
- Cell, Natural Killer
- Cells, Natural Killer
- Killer Cell, Natural
- Natural Killer Cell
|
Below are MeSH descriptors whose meaning is more general than "Killer Cells, Natural".
Below are MeSH descriptors whose meaning is more specific than "Killer Cells, Natural".
This graph shows the total number of publications written about "Killer Cells, Natural" by people in this website by year, and whether "Killer Cells, Natural" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 2 | 3 |
| 2001 | 1 | 0 | 1 |
| 2002 | 5 | 5 | 10 |
| 2003 | 1 | 3 | 4 |
| 2004 | 5 | 2 | 7 |
| 2005 | 2 | 0 | 2 |
| 2006 | 4 | 1 | 5 |
| 2007 | 3 | 3 | 6 |
| 2008 | 4 | 2 | 6 |
| 2009 | 2 | 3 | 5 |
| 2010 | 2 | 2 | 4 |
| 2011 | 4 | 2 | 6 |
| 2012 | 4 | 1 | 5 |
| 2013 | 4 | 2 | 6 |
| 2014 | 7 | 0 | 7 |
| 2015 | 6 | 2 | 8 |
| 2016 | 8 | 2 | 10 |
| 2017 | 9 | 3 | 12 |
| 2018 | 4 | 1 | 5 |
| 2019 | 14 | 1 | 15 |
| 2020 | 3 | 9 | 12 |
| 2021 | 3 | 6 | 9 |
| 2022 | 2 | 5 | 7 |
| 2023 | 0 | 12 | 12 |
| 2024 | 4 | 6 | 10 |
| 2025 | 8 | 1 | 9 |
| 2026 | 1 | 2 | 3 |
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Below are the most recent publications written about "Killer Cells, Natural" by people in Profiles.
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Understanding the Immune Response Changes to Clinical Interventions for Epstein-Barr Virus Infection Prior to Lymphoma Development in Children After Organ Transplants (UNEARTH). Pediatr Transplant. 2026 Oct; 30(10):e70487.
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TIGIT Affects CAR NK-cell Effector Function in the Solid Tumor Microenvironment by Modulating Immune Synapse Strength. Cancer Immunol Res. 2025 Oct 01; 13(10):1576-1590.
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Constitutive IL-7 signaling promotes CAR-NK cell survival in the solid tumor microenvironment but impairs tumor control. J Immunother Cancer. 2025 Jul 23; 13(7).
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High-affinity CD16A polymorphism associated with reduced risk ofsevere COVID-19. JCI Insight. 2025 Jul 08; 10(13).
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Clinical, immunologic, and genetic characteristics of 148 patients with natural killer cell deficiency. J Allergy Clin Immunol. 2025 May; 155(5):1623-1634.
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Genomic features reveal potential benefit of adding anti-PD-1 immunotherapy to treat non-upper aerodigestive tract natural killer/T-cell lymphoma. Leukemia. 2024 04; 38(4):829-839.
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NK cells as powerful therapeutic tool in cancer immunotherapy. Cell Oncol (Dordr). 2024 Jun; 47(3):733-757.
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NK Cell Therapeutics for Hematologic Malignancies: from Potential to Fruition. Curr Hematol Malig Rep. 2023 12; 18(6):264-272.
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Natural killer T cells and other innate-like T?lymphocytes as emerging platforms for allogeneic cancer cell therapy. Blood. 2023 02 23; 141(8):869-876.
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An ELF4 hypomorphic variant results in NK cell deficiency. JCI Insight. 2022 12 08; 7(23).