"Killer Cells, Natural" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.
| Descriptor ID |
D007694
|
| MeSH Number(s) |
A11.118.637.555.567.537 A15.145.229.637.555.567.537 A15.382.490.555.567.537
|
| Concept/Terms |
Killer Cells, Natural- Killer Cells, Natural
- NK Cells
- Cell, NK
- Cells, NK
- NK Cell
- Natural Killer Cells
- Cell, Natural Killer
- Cells, Natural Killer
- Killer Cell, Natural
- Natural Killer Cell
|
Below are MeSH descriptors whose meaning is more general than "Killer Cells, Natural".
Below are MeSH descriptors whose meaning is more specific than "Killer Cells, Natural".
This graph shows the total number of publications written about "Killer Cells, Natural" by people in this website by year, and whether "Killer Cells, Natural" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 5 | 4 | 9 |
| 2003 | 1 | 3 | 4 |
| 2004 | 5 | 2 | 7 |
| 2005 | 5 | 0 | 5 |
| 2006 | 4 | 0 | 4 |
| 2007 | 1 | 3 | 4 |
| 2008 | 2 | 2 | 4 |
| 2009 | 1 | 3 | 4 |
| 2010 | 2 | 2 | 4 |
| 2011 | 3 | 3 | 6 |
| 2012 | 4 | 1 | 5 |
| 2013 | 4 | 1 | 5 |
| 2014 | 7 | 1 | 8 |
| 2015 | 6 | 2 | 8 |
| 2016 | 6 | 2 | 8 |
| 2017 | 9 | 3 | 12 |
| 2018 | 6 | 1 | 7 |
| 2019 | 14 | 2 | 16 |
| 2020 | 3 | 9 | 12 |
| 2021 | 3 | 4 | 7 |
| 2022 | 2 | 5 | 7 |
| 2023 | 0 | 10 | 10 |
| 2024 | 5 | 6 | 11 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Killer Cells, Natural" by people in Profiles.
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The Golgi complex governs natural killer cell lytic granule positioning to promote directionality in cytotoxicity. Cell Rep. 2025 Jan 28; 44(1):115156.
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Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells. Cell Rep. 2025 Jan 28; 44(1):115122.
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FT538, iPSC-derived NK cells, enhance AML cell killing when combined with chemotherapy. J Cell Mol Med. 2025 Jan; 29(1):e70169.
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Preclinical and Clinical-Scale Magnetic Particle Imaging of Natural Killer Cells: in vitro and ex vivo Demonstration of Cellular Sensitivity, Resolution, and Quantification. Mol Imaging Biol. 2025 Feb; 27(1):78-88.
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IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines. Proc Natl Acad Sci U S A. 2024 Nov 26; 121(48):e2322356121.
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NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children. J Immunol. 2024 Nov 15; 213(10):1452-1466.
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Long-Term Follow-up of Levonorgestrel Intrauterine Device for Atypical Hyperplasia and Early Endometrial Cancer Reveals Relapse Characterized by Immune Exhaustion. Clin Cancer Res. 2024 Nov 15; 30(22):5073-5082.
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Anti-PD-L1 chimeric antigen receptor natural killer cell: Characterization and functional analysis. APMIS. 2024 Dec; 132(12):1115-1127.
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CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3?/ZAP70 Signaling Axis. Cancer Discov. 2024 Oct 04; 14(10):1879-1900.
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The future of immunotherapy for diffuse large B-cell lymphoma. Int J Cancer. 2025 Jan 15; 156(2):251-261.