"Theophylline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
| Descriptor ID |
D013806
|
| MeSH Number(s) |
D03.132.960.751 D03.633.100.759.758.824.751
|
| Concept/Terms |
Theophylline- Theophylline
- 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
- 1,3-Dimethylxanthine
- 1,3 Dimethylxanthine
|
Below are MeSH descriptors whose meaning is more general than "Theophylline".
Below are MeSH descriptors whose meaning is more specific than "Theophylline".
This graph shows the total number of publications written about "Theophylline" by people in this website by year, and whether "Theophylline" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Theophylline" by people in Profiles.
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Sleep quality in asthma: results of a large prospective clinical trial. J Asthma. 2008 Apr; 45(3):183-9.
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Effects of microinjection of adenosine into area postrema on heart rate, blood pressure and renal sympathetic nerve activity in rats. Sheng Li Xue Bao. 2000 Aug; 52(4):313-7.
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Effect of quinolone antimicrobials on theophylline pharmacokinetics. J Clin Pharmacol. 1989 Jul; 29(7):650-4.
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Suppressor T-cell circuit in man. Birth Defects Orig Artic Ser. 1983; 19(3):15-20.
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Effect of tetracycline hydrochloride on theophylline kinetics. Clin Pharm. 1982 Sep-Oct; 1(5):446-8.
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Effect of erythromycin on theophylline kinetics. J Allergy Clin Immunol. 1981 Dec; 68(6):427-31.
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Neutrophil chemotaxis in psoriasis. Acta Derm Venereol. 1979; 59(5):441-5.
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Defects of glucose-6-phosphate and 6-phosphogluconate dehydrogenases in Neurospora and their pleiotropic effects. Curr Top Cell Regul. 1976; 10:205-36.
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Cell density-dependent stimulation of glutamine synthetase activity in cultured mouse teratoma cells. Exp Cell Res. 1975 Sep; 94(2):459-64.