"Scleritis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.
| Descriptor ID |
D015423
|
| MeSH Number(s) |
C11.790.500
|
| Concept/Terms |
Necrotizing Scleritis- Necrotizing Scleritis
- Necrotizing Scleritides
- Scleritides, Necrotizing
- Scleritis, Necrotizing
|
Below are MeSH descriptors whose meaning is more general than "Scleritis".
Below are MeSH descriptors whose meaning is more specific than "Scleritis".
This graph shows the total number of publications written about "Scleritis" by people in this website by year, and whether "Scleritis" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Scleritis" by people in Profiles.
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Evaluation of the SUN Classification Criteria for Uveitides in an Academic Uveitis Practice. Am J Ophthalmol. 2022 09; 241:57-63.
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Scleritis, keratitis, and orbital cellulitis: isolated ocular manifestation of systemic lupus erythematosus. Lupus. 2018 Oct; 27(12):1985-1988.
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Management and outcome of microbial anterior scleritis. Cornea. 2011 Sep; 30(9):1020-3.
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Necrobiotic xanthogranuloma with posterior scleritis. Arch Ophthalmol. 2006 May; 124(5):748.
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Aspergillus flavus scleritis: successful treatment with voriconazole and caspofungin. Med Mycol. 2005 Nov; 43(7):651-5.
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Recombinant human tumor necrosis factor receptor Fc fusion protein (Etanercept): experience as a therapy for sight-threatening scleritis and sterile corneal ulceration. Eye Contact Lens. 2004 Jan; 30(1):2-5.
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Scleritis as the initial clinical manifestation of graft-versus-host disease after allogenic bone marrow transplantation. Am J Ophthalmol. 2002 Jun; 133(6):843-5.
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Therapy of nonnecrotizing anterior scleritis with subconjunctival corticosteroid injection. Ophthalmology. 1995 May; 102(5):718-24.
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Necrotizing scleritis and transient myopia following strabismus surgery. Ophthalmic Surg. 1993 Dec; 24(12):839-41.
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Fulminant pseudomonal keratitis and scleritis in human immunodeficiency virus-infected patients. Arch Ophthalmol. 1991 Apr; 109(4):503-5.