"Retinal Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Descriptor ID |
D012162
|
| MeSH Number(s) |
C11.768.585
|
| Concept/Terms |
Retinal Degeneration- Retinal Degeneration
- Degeneration, Retinal
- Degenerations, Retinal
- Retinal Degenerations
|
Below are MeSH descriptors whose meaning is more general than "Retinal Degeneration".
Below are MeSH descriptors whose meaning is more specific than "Retinal Degeneration".
This graph shows the total number of publications written about "Retinal Degeneration" by people in this website by year, and whether "Retinal Degeneration" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 4 | 0 | 4 |
| 1998 | 1 | 0 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 1 | 0 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 2 | 0 | 2 |
| 2006 | 2 | 1 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 3 | 0 | 3 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 1 | 3 |
| 2015 | 4 | 0 | 4 |
| 2016 | 3 | 1 | 4 |
| 2017 | 4 | 0 | 4 |
| 2018 | 5 | 0 | 5 |
| 2019 | 1 | 0 | 1 |
| 2020 | 3 | 1 | 4 |
| 2021 | 3 | 0 | 3 |
| 2022 | 4 | 1 | 5 |
| 2023 | 2 | 0 | 2 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Retinal Degeneration" by people in Profiles.
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Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency. Autophagy. 2018; 14(8):1419-1434.
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Hypomorphic mutations identified in the candidate Leber congenital amaurosis gene CLUAP1. Genet Med. 2016 10; 18(10):1044-51.
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Nephronophthisis and retinal degeneration in tmem218-/- mice: a novel mouse model for Senior-L?ken syndrome? Vet Pathol. 2015 May; 52(3):580-95.
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The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration. PLoS Biol. 2014 Apr; 12(4):e1001847.
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Arginase 2 deficiency reduces hyperoxia-mediated retinal neurodegeneration through the regulation of polyamine metabolism. Cell Death Dis. 2014 Feb 20; 5:e1075.
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Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells. Stem Cells Transl Med. 2012 Feb; 1(2):96-109.
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Topical mydriatics affect light-evoked retinal responses in anesthetized mice. Invest Ophthalmol Vis Sci. 2010 Jan; 51(1):567-76.
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Neural reprogramming in retinal degeneration. Invest Ophthalmol Vis Sci. 2007 Jul; 48(7):3364-71.
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Time course analysis of gene expression during light-induced photoreceptor cell death and regeneration in albino zebrafish. Dev Neurobiol. 2007 Jul; 67(8):1009-31.
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Genetic ablation of cone photoreceptors eliminates retinal folds in the retinal degeneration 7 (rd7) mouse. Invest Ophthalmol Vis Sci. 2007 Jun; 48(6):2799-805.