Lymphocytes, Tumor-Infiltrating
"Lymphocytes, Tumor-Infiltrating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lymphocytes that show specificity for autologous tumor cells. Ex vivo isolation and culturing of TIL with interleukin-2, followed by reinfusion into the patient, is one form of adoptive immunotherapy of cancer.
| Descriptor ID |
D016246
|
| MeSH Number(s) |
A11.118.637.555.567.650 A15.145.229.637.555.567.650 A15.382.490.555.567.650
|
| Concept/Terms |
Lymphocytes, Tumor-Infiltrating- Lymphocytes, Tumor-Infiltrating
- Lymphocytes, Tumor Infiltrating
- Tumor-Infiltrating Lymphocytes
- Lymphocyte, Tumor-Infiltrating
- Tumor Infiltrating Lymphocytes
- Tumor-Infiltrating Lymphocyte
Tumor-Derived Activated Cells- Tumor-Derived Activated Cells
- Activated Cell, Tumor-Derived
- Activated Cells, Tumor-Derived
- Tumor Derived Activated Cells
- Tumor-Derived Activated Cell
|
Below are MeSH descriptors whose meaning is more general than "Lymphocytes, Tumor-Infiltrating".
Below are MeSH descriptors whose meaning is more specific than "Lymphocytes, Tumor-Infiltrating".
This graph shows the total number of publications written about "Lymphocytes, Tumor-Infiltrating" by people in this website by year, and whether "Lymphocytes, Tumor-Infiltrating" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 3 | 0 | 3 |
| 1997 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 2 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 2 | 3 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 2 | 4 |
| 2017 | 3 | 4 | 7 |
| 2018 | 3 | 3 | 6 |
| 2019 | 6 | 2 | 8 |
| 2020 | 1 | 3 | 4 |
| 2021 | 6 | 6 | 12 |
| 2022 | 0 | 6 | 6 |
| 2023 | 1 | 1 | 2 |
| 2024 | 2 | 4 | 6 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lymphocytes, Tumor-Infiltrating" by people in Profiles.
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High tumor CD161 expression predicts a survival advantage and marks a Th1-skewed microenvironment. Front Immunol. 2025; 16:1522755.
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Development of a RIPK1 degrader to enhance antitumor immunity. Nat Commun. 2024 12 16; 15(1):10683.
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Immune landscape of isocitrate dehydrogenase-stratified primary and recurrent human gliomas. Neuro Oncol. 2024 Dec 05; 26(12):2239-2255.
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Differential Infiltration of Key Immune T-Cell Populations Across Malignancies Varying by Immunogenic Potential and the Likelihood of Response to Immunotherapy. Cells. 2024 12 03; 13(23).
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CD8+ Tumor-Infiltrating Lymphocytes in Head and Neck Cancer: A Review. JCO Precis Oncol. 2024 Oct; 8:e2400183.
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Neoadjuvant vidutolimod and nivolumab in high-risk resectable melanoma: A prospective phase II trial. Cancer Cell. 2024 Nov 11; 42(11):1898-1918.e12.
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Integrative Multiomic Profiling of Triple-Negative Breast Cancer for Identifying Suitable Therapies. Clin Cancer Res. 2024 Oct 15; 30(20):4768-4779.
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NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs. Cancer Immunol Res. 2024 Oct 01; 12(10):1421-1437.
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Astrocyte-induced Cdk5 expedites breast cancer brain metastasis by suppressing MHC-I expression to evade immune recognition. Nat Cell Biol. 2024 10; 26(10):1773-1789.
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MCT4 is an independent prognostic factor and affects immune cell infiltration in patients with colorectal liver oligometastases. Clin Transl Oncol. 2025 Apr; 27(4):1681-1694.