Nitric Oxide

"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.

Descriptor ID	D009569
MeSH Number(s)	D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
Concept/Terms	Nitric Oxide Nitric Oxide Oxide, Nitric Nitrogen Monoxide Monoxide, Nitrogen Nitric Oxide, Endothelium-Derived Endothelium-Derived Nitric Oxide Nitric Oxide, Endothelium Derived Endogenous Nitrate Vasodilator Nitrate Vasodilator, Endogenous Vasodilator, Endogenous Nitrate Mononitrogen Monoxide Monoxide, Mononitrogen

Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".

Chemicals and Drugs [D]
Inorganic Chemicals [D01]
Free Radicals [D01.339]
Nitric Oxide [D01.339.387]
Nitrogen Compounds [D01.625]
Nitrogen Oxides [D01.625.550]
Nitric Oxide [D01.625.550.500]
Reactive Nitrogen Species [D01.625.700]
Nitric Oxide [D01.625.700.500]
Oxygen Compounds [D01.650]
Oxides [D01.650.550]
Nitrogen Oxides [D01.650.550.587]
Nitric Oxide [D01.650.550.587.600]

Below are MeSH descriptors whose meaning is related to "Nitric Oxide".

Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.

Bar chart showing 453 publications over 30 distinct years, with a maximum of 24 publications in 2003 and 2004 and 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	2	0	2
1993	4	1	5
1994	8	2	10
1995	8	3	11
1996	6	2	8
1997	12	1	13
1998	12	6	18
1999	15	3	18
2000	11	11	22
2001	7	12	19
2002	11	7	18
2003	19	5	24
2004	16	8	24
2005	13	9	22
2006	10	8	18
2007	8	16	24
2008	9	14	23
2009	5	8	13
2010	13	10	23
2011	14	8	22
2012	11	3	14
2013	5	10	15
2014	13	10	23
2015	3	4	7
2016	6	11	17
2017	4	4	8
2018	7	8	15
2019	1	4	5
2020	1	6	7
2021	1	4	5

Below are the most recent publications written about "Nitric Oxide" by people in Profiles.

Matrone G, Jung SY, Choi JM, Jain A, Leung HE, Rajapakshe K, Coarfa C, Rodor J, Denvir MA, Baker AH, Cooke JP. Nuclear S-nitrosylation impacts tissue regeneration in zebrafish. Nat Commun. 2021 11 01; 12(1):6282.

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Fernandez-Moure JS, Van Eps JL, Scherba JC, Haddix S, Livingston M, Bryan NS, Cantu C, Valson C, Taraballi F, Kaplan LJ, Olsen R, Tasciotti E. Polyester Mesh Functionalization with Nitric Oxide-Releasing Silica Nanoparticles Reduces Early Methicillin-Resistant Staphylococcus aureus Contamination. Surg Infect (Larchmt). 2021 Nov; 22(9):910-922.

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Pirie E, Oh CK, Zhang X, Han X, Cieplak P, Scott HR, Deal AK, Ghatak S, Martinez FJ, Yeo GW, Yates JR, Nakamura T, Lipton SA. S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD. Proc Natl Acad Sci U S A. 2021 03 16; 118(11).

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Coleman RD, Chartan CA, Mourani PM. Intensive care management of right ventricular failure and pulmonary hypertension crises. Pediatr Pulmonol. 2021 03; 56(3):636-648.

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Pepper AN, Hanania NA, Humbert M, Casale TB. How to Assess Effectiveness of Biologics for Asthma and What Steps to Take When There Is Not Benefit. J Allergy Clin Immunol Pract. 2021 03; 9(3):1081-1088.

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Patel S, Hussain T. Synergism between Angiotensin receptors ligands: Role of Angiotensin-(1-7) in modulating AT2 R agonist response on nitric oxide in kidney cells. Pharmacol Res Perspect. 2020 12; 8(6):e00667.

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Asleh J, Shofty B, Cohen N, Kavushansky A, López-Juárez A, Constantini S, Ratner N, Kahn I. Brain-wide structural and functional disruption in mice with oligodendrocyte-specific Nf1 deletion is rescued by inhibition of nitric oxide synthase. Proc Natl Acad Sci U S A. 2020 09 08; 117(36):22506-22513.

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Bose S, Bime C, Henderson RJ, Blake KV, Castro M, DiMango E, Hanania NA, Holbrook JT, Irvin CG, Kraft M, Peters SP, Reibman J, Sugar EA, Sumino K, Wise RA, Rogers L. Biomarkers of Type 2 Airway Inflammation as Predictors of Loss of Asthma Control During Step-Down Therapy for Well-Controlled Disease: The Long-Acting Beta-Agonist Step-Down Study (LASST). J Allergy Clin Immunol Pract. 2020 Nov - Dec; 8(10):3474-3481.

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Villarreal EG, Aiello S, Evey LW, Flores S, Loomba RS. Effects of inhaled nitric oxide on haemodynamics and gas exchange in children after having undergone cardiac surgery utilising cardiopulmonary bypass. Cardiol Young. 2020 Aug; 30(8):1151-1156.

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Buhl R, Korn S, Menzies-Gow A, Aubier M, Chapman KR, Canonica GW, Picado C, Donica M, Kuhlbusch K, Korom S, Hanania NA. Prospective, Single-Arm, Longitudinal Study of Biomarkers in Real-World Patients with Severe Asthma. J Allergy Clin Immunol Pract. 2020 09; 8(8):2630-2639.e6.

View in: PubMed

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