"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
|
| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
|
| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
|
Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 5 | 1 | 6 |
| 1996 | 2 | 1 | 3 |
| 1997 | 8 | 1 | 9 |
| 1998 | 5 | 5 | 10 |
| 1999 | 11 | 3 | 14 |
| 2000 | 6 | 1 | 7 |
| 2001 | 6 | 4 | 10 |
| 2002 | 8 | 6 | 14 |
| 2003 | 10 | 3 | 13 |
| 2004 | 10 | 4 | 14 |
| 2005 | 11 | 4 | 15 |
| 2006 | 7 | 3 | 10 |
| 2007 | 6 | 9 | 15 |
| 2008 | 3 | 12 | 15 |
| 2009 | 4 | 5 | 9 |
| 2010 | 6 | 6 | 12 |
| 2011 | 9 | 9 | 18 |
| 2012 | 8 | 2 | 10 |
| 2013 | 6 | 8 | 14 |
| 2014 | 6 | 7 | 13 |
| 2015 | 3 | 4 | 7 |
| 2016 | 4 | 7 | 11 |
| 2017 | 2 | 4 | 6 |
| 2018 | 7 | 10 | 17 |
| 2019 | 1 | 6 | 7 |
| 2020 | 1 | 5 | 6 |
| 2021 | 1 | 4 | 5 |
| 2022 | 1 | 3 | 4 |
| 2023 | 2 | 5 | 7 |
| 2024 | 2 | 1 | 3 |
| 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Inflammatory and clinical risk factors for asthma attacks (ORACLE2): a patient-level meta-analysis of control groups of 22 randomised trials. Lancet Respir Med. 2025 Jun; 13(6):505-516.
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Methylated Arginine Metabolites as Biomarkers for Clinical Status and Response to Type 5 Phosphodiesterase Inhibition in Patients With Fontan Circulation. J Am Heart Assoc. 2025 Apr; 14(7):e038061.
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The Role of Nitric Oxide in the Sweep Gas for Patients Receiving Extracorporeal Membrane Oxygenation or Cardiopulmonary Bypass. Can J Cardiol. 2025 Apr; 41(4):621-629.
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NOxBOXi fluctuations delivering inhaled nitric oxide via high-frequency oscillator: A conundrum and a hypothesis. Pediatr Pulmonol. 2024 Jul; 59(7):2024-2025.
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Lebrikizumab in Uncontrolled Asthma: Reanalysis in a Well-Defined Type 2 Population. J Allergy Clin Immunol Pract. 2024 May; 12(5):1215-1224.e3.
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Nitric oxide is required for lung alveolarization revealed by deficiency of argininosuccinate lyase. Hum Mol Genet. 2023 12 12; 33(1):33-37.
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Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide-mediated dysregulation of claudin expression. JCI Insight. 2023 09 08; 8(17).
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Dimethylarginine Dimethylaminohydrolase - 1 expression is increased under tBHP-induced oxidative stress regulates nitric oxide production in PCa cells attenuates mitochondrial ROS-mediated apoptosis. Nitric Oxide. 2023 09 01; 138-139:70-84.
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Effect of radon exposure on asthma morbidity in the School Inner-City Asthma study. Pediatr Pulmonol. 2023 Jul; 58(7):2042-2049.
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Inhaled Nitric Oxide Utilization in Congenital Diaphragmatic Hernia Treated With Extracorporeal Life Support: A Propensity Score Analysis. ASAIO J. 2023 05 01; 69(5):504-510.