"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
|
| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
|
| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
|
Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 2 | 1 | 3 |
| 1992 | 3 | 0 | 3 |
| 1993 | 4 | 1 | 5 |
| 1994 | 8 | 2 | 10 |
| 1995 | 9 | 3 | 12 |
| 1996 | 7 | 2 | 9 |
| 1997 | 14 | 1 | 15 |
| 1998 | 11 | 5 | 16 |
| 1999 | 14 | 3 | 17 |
| 2000 | 11 | 12 | 23 |
| 2001 | 6 | 12 | 18 |
| 2002 | 14 | 9 | 23 |
| 2003 | 20 | 6 | 26 |
| 2004 | 17 | 8 | 25 |
| 2005 | 13 | 12 | 25 |
| 2006 | 11 | 10 | 21 |
| 2007 | 10 | 16 | 26 |
| 2008 | 13 | 11 | 24 |
| 2009 | 13 | 11 | 24 |
| 2010 | 13 | 14 | 27 |
| 2011 | 17 | 7 | 24 |
| 2012 | 15 | 3 | 18 |
| 2013 | 8 | 11 | 19 |
| 2014 | 14 | 10 | 24 |
| 2015 | 6 | 7 | 13 |
| 2016 | 8 | 14 | 22 |
| 2017 | 6 | 7 | 13 |
| 2018 | 9 | 8 | 17 |
| 2019 | 2 | 5 | 7 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Patel SN, Fatima N, Ali R, Hussain T. Emerging Role of Angiotensin AT2 Receptor in Anti-Inflammation: An Update. Curr Pharm Des. 2020; 26(4):492-500.
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Narendra D, Blixt J, Hanania NA. Immunological biomarkers in severe asthma. Semin Immunol. 2019 12; 46:101332.
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Choudhry S, Wang Y, Denfield SW, Cabrera AG, Price JF, Tunuguntla HP, Dharnidharka VR, Canter CE, Dreyer WJ. A Recipient Risk Prediction Tool for Short-term Mortality After Pediatric Heart Transplantation. Transplantation. 2019 11; 103(11):2434-2439.
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Hawkins CL, Davies MJ. Detection, identification, and quantification of oxidative protein modifications. J Biol Chem. 2019 12 20; 294(51):19683-19708.
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Chhabria K, Vouros A, Gray C, MacDonald RB, Jiang Z, Wilkinson RN, Plant K, Vasilaki E, Howarth C, Chico TJA. Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behaviour in zebrafish. Dis Model Mech. 2019 09 25; 12(9).
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Wong J, Loomba RS, Evey L, Bronicki RA, Flores S. Postoperative Inhaled Nitric Oxide Does Not Decrease Length of Stay in Pediatric Cardiac Surgery Admissions. Pediatr Cardiol. 2019 Dec; 40(8):1559-1568.
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Kugler EC, van Lessen M, Daetwyler S, Chhabria K, Savage AM, Silva V, Plant K, MacDonald RB, Huisken J, Wilkinson RN, Schulte-Merker S, Armitage P, Chico TJ. Cerebrovascular endothelial cells form transient Notch-dependent cystic structures in zebrafish. EMBO Rep. 2019 08; 20(8):e47047.
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Bryan NS, Lefer DJ. Update on Gaseous Signaling Molecules Nitric Oxide and Hydrogen Sulfide: Strategies to Capture their Functional Activity for Human Therapeutics. Mol Pharmacol. 2019 07; 96(1):109-114.
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Pavord ID, Hanania NA. Controversies in Allergy: Should Severe Asthma with Eosinophilic Phenotype Always Be Treated with Anti-IL-5 Therapies. J Allergy Clin Immunol Pract. 2019 May - Jun; 7(5):1430-1436.
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Estienne A, Portela VM, Choi Y, Zamberlam G, Boerboom D, Roussel V, Meinsohn MC, Brännström M, Curry TE, Jo M, Price CA. The endogenous hydrogen sulfide generating system regulates ovulation. Free Radic Biol Med. 2019 07; 138:43-52.