Polymorphism, Single-Stranded Conformational
"Polymorphism, Single-Stranded Conformational" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
Descriptor ID |
D018807
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MeSH Number(s) |
G05.365.795.600
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Concept/Terms |
Polymorphism, Single-Stranded Conformational- Polymorphism, Single-Stranded Conformational
- Polymorphism, Single Stranded Conformational
- SSCP
- Single-Stranded Conformational Polymorphism
- Conformational Polymorphism, Single-Stranded
- Conformational Polymorphisms, Single-Stranded
- Polymorphisms, Single-Stranded Conformational
- Single Stranded Conformational Polymorphism
- Single-Stranded Conformational Polymorphisms
|
Below are MeSH descriptors whose meaning is more general than "Polymorphism, Single-Stranded Conformational".
Below are MeSH descriptors whose meaning is more specific than "Polymorphism, Single-Stranded Conformational".
This graph shows the total number of publications written about "Polymorphism, Single-Stranded Conformational" by people in this website by year, and whether "Polymorphism, Single-Stranded Conformational" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 2 | 11 | 13 |
1996 | 2 | 12 | 14 |
1997 | 1 | 21 | 22 |
1998 | 1 | 17 | 18 |
1999 | 0 | 18 | 18 |
2000 | 0 | 21 | 21 |
2001 | 1 | 11 | 12 |
2002 | 1 | 7 | 8 |
2003 | 0 | 8 | 8 |
2004 | 0 | 3 | 3 |
2005 | 0 | 3 | 3 |
2006 | 0 | 4 | 4 |
2008 | 0 | 5 | 5 |
2009 | 0 | 1 | 1 |
2010 | 1 | 1 | 2 |
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Below are the most recent publications written about "Polymorphism, Single-Stranded Conformational" by people in Profiles.
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Multicentric breast cancer: clonality and prognostic studies. Breast Cancer Res Treat. 2011 Oct; 129(3):703-16.
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Examination of the MASH1 gene in patients with Parkinson's disease. Biochem Biophys Res Commun. 2010 Feb 19; 392(4):548-50.
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GIGYF2 Asn56Ser and Asn457Thr mutations in Parkinson disease patients. Neurosci Lett. 2009 May 01; 454(3):209-11.
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Association of reproductive performance with SNPs of FOXL2 gene by SSCP in Japanese flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2009 May; 153(1):1-7.
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Polymorphisms within promoter of Japanese flounder (Paralichthys olivaceus) ovary cytochrome P450-c19 (CYP19a) gene associated with reproductive traits. Fish Physiol Biochem. 2009 Aug; 35(3):333-40.
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Evidence that senescent human prostate epithelial cells enhance tumorigenicity: cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT. Int J Cancer. 2008 Apr 01; 122(7):1483-95.
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Identification of estrogen receptor alpha gene polymorphisms by SSCP and its effect on reproductive traits in Japanese flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2008 Jul; 150(3):278-83.
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Clinical and molecular diagnosis of a Costa Rican family with autosomal recessive myotonia congenita (Becker disease) carrying a new mutation in the CLCN1 gene. Rev Biol Trop. 2008 Mar; 56(1):1-11.
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Gene symbol: CLCN1. Disease: Myotonia congenita. Hum Genet. 2008 Feb; 123(1):104-5.
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Polymorphisms in drug metabolism genes, smoking, and p53 mutations in breast cancer. Mol Carcinog. 2008 Feb; 47(2):88-99.