"Oncolytic Viruses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tumor-selective, replication competent VIRUSES that have antineoplastic effects. This is achieved by producing cytotoxicity-enhancing proteins and/or eliciting an antitumor immune response. They are genetically engineered so that they can replicate in CANCER cells but not in normal cells, and are used in ONCOLYTIC VIROTHERAPY.
Descriptor ID |
D050504
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MeSH Number(s) |
B04.700
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Oncolytic Viruses".
Below are MeSH descriptors whose meaning is more specific than "Oncolytic Viruses".
This graph shows the total number of publications written about "Oncolytic Viruses" by people in this website by year, and whether "Oncolytic Viruses" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2005 | 1 | 0 | 1 |
2006 | 2 | 0 | 2 |
2007 | 2 | 2 | 4 |
2008 | 5 | 1 | 6 |
2009 | 1 | 2 | 3 |
2010 | 2 | 0 | 2 |
2011 | 1 | 0 | 1 |
2013 | 2 | 1 | 3 |
2014 | 4 | 1 | 5 |
2015 | 4 | 1 | 5 |
2016 | 3 | 2 | 5 |
2017 | 6 | 2 | 8 |
2018 | 3 | 0 | 3 |
2019 | 3 | 0 | 3 |
2020 | 3 | 1 | 4 |
2021 | 10 | 0 | 10 |
2022 | 4 | 0 | 4 |
2023 | 5 | 0 | 5 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Oncolytic Viruses" by people in Profiles.
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Chimeric oncolytic adenovirus evades neutralizing antibodies from human patients and exhibits enhanced anti-glioma efficacy in immunized mice. Mol Ther. 2024 Mar 06; 32(3):722-733.
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Promises of oncolytic viral therapy for adult and children with brain glioma. Curr Opin Oncol. 2023 11 01; 35(6):529-535.
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Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models. J Transl Med. 2023 07 06; 21(1):444.
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Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial. Nat Med. 2023 Jun; 29(6):1370-1378.
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Oncolytic viruses as treatment for adult and pediatric high-grade gliomas: On the way to clinical success. Int Rev Cell Mol Biol. 2023; 379:169-188.
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Ultralow-dose binary oncolytic/helper-dependent adenovirus promotes antitumor activity in preclinical and clinical studies. Sci Adv. 2023 03 29; 9(13):eade6790.
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Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry. J Immunother Cancer. 2022 07; 10(7).
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Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma. N Engl J Med. 2022 06 30; 386(26):2471-2481.
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Convection Enhanced Delivery of the Oncolytic Adenovirus Delta24-RGD in Patients with Recurrent GBM: A Phase I Clinical Trial Including Correlative Studies. Clin Cancer Res. 2022 04 14; 28(8):1572-1585.
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Local Treatment of a Pediatric Osteosarcoma Model with a 4-1BBL Armed Oncolytic Adenovirus Results in an Antitumor Effect and Leads to Immune Memory. Mol Cancer Ther. 2022 03 01; 21(3):471-480.