"Muscarinic Agonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that bind to and activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate.
Descriptor ID |
D018721
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MeSH Number(s) |
D27.505.519.625.120.140.500 D27.505.696.577.120.140.500
|
Concept/Terms |
Muscarinic Agonists- Muscarinic Agonists
- Agonists, Muscarinic
- Muscarinic Agonist
- Agonist, Muscarinic
- Cholinergic Muscarinic Agonists
- Agonists, Cholinergic Muscarinic
- Muscarinic Agonists, Cholinergic
- Cholinergic Agonist, Muscarinic
- Agonist, Muscarinic Cholinergic
- Muscarinic Cholinergic Agonist
- Cholinergic Agonists, Muscarinic
- Agonists, Muscarinic Cholinergic
- Muscarinic Cholinergic Agonists
|
Below are MeSH descriptors whose meaning is more general than "Muscarinic Agonists".
Below are MeSH descriptors whose meaning is more specific than "Muscarinic Agonists".
This graph shows the total number of publications written about "Muscarinic Agonists" by people in this website by year, and whether "Muscarinic Agonists" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 0 | 1 |
1997 | 0 | 1 | 1 |
2000 | 1 | 0 | 1 |
2006 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "Muscarinic Agonists" by people in Profiles.
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Impaired Na?-dependent regulation of acetylcholine-activated inward-rectifier K? current modulates action potential rate dependence in patients with chronic atrial fibrillation. J Mol Cell Cardiol. 2013 Aug; 61:142-52.
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Effectiveness of cevimeline to improve oral health in patients with postradiation xerostomia. Head Neck. 2012 Aug; 34(8):1136-42.
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Dynamic control of glutamatergic synaptic input in the spinal cord by muscarinic receptor subtypes defined using knockout mice. J Biol Chem. 2010 Dec 24; 285(52):40427-37.
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Role of M2, M3, and M4 muscarinic receptor subtypes in the spinal cholinergic control of nociception revealed using siRNA in rats. J Neurochem. 2009 Nov; 111(4):1000-10.
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Signaling mechanisms mediating muscarinic enhancement of GABAergic synaptic transmission in the spinal cord. Neuroscience. 2009 Feb 18; 158(4):1577-88.
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The glutamatergic nature of TRPV1-expressing neurons in the spinal dorsal horn. J Neurochem. 2009 Jan; 108(1):305-18.
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Control of glycinergic input to spinal dorsal horn neurons by distinct muscarinic receptor subtypes revealed using knockout mice. J Pharmacol Exp Ther. 2007 Dec; 323(3):963-71.
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Open-label, long-term safety study of cevimeline in the treatment of postirradiation xerostomia. Int J Radiat Oncol Biol Phys. 2007 Dec 01; 69(5):1369-76.
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A controlled release pilocarpine buccal insert in the treatment of Sj?gren's syndrome. Br Dent J. 2007 Apr 14; 202(7):E17; discussion 404-5.
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Using caveolin-1 knockout mouse to study impaired detrusor contractility and disrupted muscarinic activity in the aging bladder. Urology. 2007 Feb; 69(2):407-11.