"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
Descriptor ID |
D008213
|
MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.450.050.400.545 G12.565
|
Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blast Transformation
- Blastogenesis
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Lymphoblast
- Lymphoblast Transformation
- Transformation, Blast
- Transformation, Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 7 | 7 | 14 |
1995 | 8 | 12 | 20 |
1996 | 4 | 7 | 11 |
1997 | 7 | 14 | 21 |
1998 | 8 | 9 | 17 |
1999 | 6 | 13 | 19 |
2000 | 7 | 21 | 28 |
2001 | 6 | 10 | 16 |
2002 | 6 | 16 | 22 |
2003 | 4 | 19 | 23 |
2004 | 10 | 26 | 36 |
2005 | 13 | 24 | 37 |
2006 | 7 | 26 | 33 |
2007 | 11 | 28 | 39 |
2008 | 7 | 26 | 33 |
2009 | 13 | 23 | 36 |
2010 | 9 | 23 | 32 |
2011 | 15 | 33 | 48 |
2012 | 4 | 16 | 20 |
2013 | 7 | 22 | 29 |
2014 | 7 | 26 | 33 |
2015 | 4 | 16 | 20 |
2016 | 4 | 28 | 32 |
2017 | 4 | 31 | 35 |
2018 | 5 | 18 | 23 |
2019 | 8 | 25 | 33 |
2020 | 4 | 16 | 20 |
2021 | 7 | 9 | 16 |
2022 | 0 | 2 | 2 |
2023 | 0 | 4 | 4 |
2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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BTN1A1 is a novel immune checkpoint mutually exclusive to PD-L1. J Immunother Cancer. 2024 Mar 14; 12(3).
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IL-12 reprograms CAR-expressing natural killer T cells to long-lived Th1-polarized cells with potent antitumor activity. Nat Commun. 2024 Jan 02; 15(1):89.
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The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity. Cancer Cell. 2023 07 10; 41(7):1207-1221.e12.
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Ribonuclease 1 Enhances Antitumor Immunity against Breast Cancer by Boosting T cell Activation. Int J Biol Sci. 2023; 19(10):2957-2973.
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Overview of human B-cell development and antibody deficiencies. J Immunol Methods. 2023 08; 519:113485.
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LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells. Cancer Immunol Res. 2023 02 03; 11(2):171-183.
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CD70 is a potential target biomarker in peripheral T-cell lymphomas. Histopathology. 2022 08; 81(2):272-275.
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Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses. Sci Transl Med. 2022 03 16; 14(636):eabg8402.
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The CD6/ALCAM pathway promotes lupus nephritis via T cell-mediated responses. J Clin Invest. 2022 01 04; 132(1).
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Coenzyme A fuels T?cell anti-tumor immunity. Cell Metab. 2021 12 07; 33(12):2415-2427.e6.