"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
| Descriptor ID |
D008213
|
| MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.450.050.400.545 G12.565
|
| Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blast Transformation
- Blastogenesis
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Lymphoblast
- Lymphoblast Transformation
- Transformation, Blast
- Transformation, Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 7 | 7 | 14 |
| 1995 | 9 | 12 | 21 |
| 1996 | 6 | 8 | 14 |
| 1997 | 7 | 14 | 21 |
| 1998 | 7 | 10 | 17 |
| 1999 | 7 | 15 | 22 |
| 2000 | 8 | 24 | 32 |
| 2001 | 7 | 19 | 26 |
| 2002 | 7 | 25 | 32 |
| 2003 | 4 | 17 | 21 |
| 2004 | 10 | 26 | 36 |
| 2005 | 13 | 24 | 37 |
| 2006 | 6 | 24 | 30 |
| 2007 | 12 | 28 | 40 |
| 2008 | 6 | 26 | 32 |
| 2009 | 13 | 22 | 35 |
| 2010 | 9 | 22 | 31 |
| 2011 | 14 | 32 | 46 |
| 2012 | 4 | 16 | 20 |
| 2013 | 6 | 22 | 28 |
| 2014 | 6 | 25 | 31 |
| 2015 | 6 | 14 | 20 |
| 2016 | 4 | 28 | 32 |
| 2017 | 3 | 28 | 31 |
| 2018 | 5 | 19 | 24 |
| 2019 | 8 | 28 | 36 |
| 2020 | 3 | 16 | 19 |
| 2021 | 7 | 8 | 15 |
| 2022 | 0 | 2 | 2 |
| 2023 | 1 | 4 | 5 |
| 2024 | 1 | 6 | 7 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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HIF1a-regulated glycolysis promotes activation-induced cell death and IFN-? induction in hypoxic T cells. Nat Commun. 2024 Oct 30; 15(1):9394.
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Histone lactylation drives CD8+ T cell metabolism and function. Nat Immunol. 2024 Nov; 25(11):2140-2151.
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NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs. Cancer Immunol Res. 2024 Oct 01; 12(10):1421-1437.
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TFEB activation hallmarks antigenic experience of B lymphocytes and directs germinal center fate decisions. Nat Commun. 2024 Aug 14; 15(1):6971.
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6-Formylindolo[3,2-b]carbazole, a potent ligand for the aryl hydrocarbon receptor, attenuates concanavalin-induced hepatitis by limiting T-cell activation and infiltration of proinflammatory CD11b+ Kupffer cells. J Leukoc Biol. 2024 05 29; 115(6):1070-1083.
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Consensus recommendations on the management of toxicity associated with CD3?CD20 bispecific antibody therapy. Blood. 2024 04 18; 143(16):1565-1575.
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BTN1A1 is a novel immune checkpoint mutually exclusive to PD-L1. J Immunother Cancer. 2024 Mar 14; 12(3).
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IL-12 reprograms CAR-expressing natural killer T cells to long-lived Th1-polarized cells with potent antitumor activity. Nat Commun. 2024 01 02; 15(1):89.
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The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity. Cancer Cell. 2023 07 10; 41(7):1207-1221.e12.
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Activation of T Lymphocytes with Anti-PDL1-BiTE in the Presence of Adipose-Derived Mesenchymal Stem Cells (ASCs). Biomed Res Int. 2023; 2023:7692726.