Pyrrolidonecarboxylic Acid
"Pyrrolidonecarboxylic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclized derivative of L-GLUTAMIC ACID. Elevated blood levels may be associated with problems of GLUTAMINE or GLUTATHIONE metabolism.
| Descriptor ID |
D011761
|
| MeSH Number(s) |
D03.383.773.812.718 D12.125.067.625.850 D12.125.072.401.761
|
| Concept/Terms |
Pyrrolidonecarboxylic Acid- Pyrrolidonecarboxylic Acid
- 5-Oxoproline
- Pidolic Acid
- Pyroglutamic Acid
- 5-Ketoproline
- 5-Oxopyrrolidine-2-Carboxylic Acid
|
Below are MeSH descriptors whose meaning is more general than "Pyrrolidonecarboxylic Acid".
Below are MeSH descriptors whose meaning is more specific than "Pyrrolidonecarboxylic Acid".
This graph shows the total number of publications written about "Pyrrolidonecarboxylic Acid" by people in this website by year, and whether "Pyrrolidonecarboxylic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pyrrolidonecarboxylic Acid" by people in Profiles.
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Adipokinetic hormone receptor gene identification and its role in triacylglycerol metabolism in the blood-sucking insect Rhodnius prolixus. Insect Biochem Mol Biol. 2016 Feb; 69:51-60.
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Serum metabolomic profiling and incident CKD among African Americans. Clin J Am Soc Nephrol. 2014 Aug 07; 9(8):1410-7.
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An artifact in LC-MS/MS measurement of glutamine and glutamic acid: in-source cyclization to pyroglutamic acid. Anal Chem. 2014 Jun 17; 86(12):5633-7.
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Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. Genet Epidemiol. 2013 Dec; 37(8):840-5.
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GnRH-(1-5) transactivates EGFR in Ishikawa human endometrial cells via an orphan G protein-coupled receptor. Mol Endocrinol. 2014 Jan; 28(1):80-98.
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Luteinizing Hormone-Releasing Hormone (LHRH)-I antagonist cetrorelix inhibits myeloma cell growth in vitro and in vivo. Mol Cancer Ther. 2011 Jan; 10(1):148-58.
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An efficient synthesis of the constrained peptidomimetic 2-oxo-3-(N-9-fluorenyloxycarbonylamino)-1-azabicyclo[4.3.0]nonane-9-carboxylic acid from pyroglutamic acid. J Org Chem. 2005 Nov 25; 70(24):10128-31.
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Leptin regulates bone formation via the sympathetic nervous system. Cell. 2002 Nov 01; 111(3):305-17.
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Characteristics of GnRH binding in the gonads and effects of lamprey GnRH-I and -III on reproduction in the adult sea lamprey. Gen Comp Endocrinol. 1997 Nov; 108(2):327-39.
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Mutations in the glutathione synthetase gene cause 5-oxoprolinuria. Nat Genet. 1996 Nov; 14(3):361-5.