"Aryldialkylphosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme which catalyzes the hydrolysis of an aryl-dialkyl phosphate to form dialkyl phosphate and an aryl alcohol. It can hydrolyze a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may also mediate an enzymatic protection of LOW DENSITY LIPOPROTEINS against oxidative modification and the consequent series of events leading to ATHEROMA formation. The enzyme was previously regarded to be identical with Arylesterase (EC 3.1.1.2).
| Descriptor ID |
D043303
|
| MeSH Number(s) |
D08.811.277.352.660.500
|
| Concept/Terms |
Aryldialkylphosphatase- Aryldialkylphosphatase
- Arylalkylphosphatase
- Homocysteine Thiolactone Hydrolase
- Hydrolase, Homocysteine Thiolactone
- Thiolactone Hydrolase, Homocysteine
- OPA Anhydrase
- Anhydrase, OPA
- Paraoxonase
- Organophosphorus Acid Anhydrase
- Acid Anhydrase, Organophosphorus
- Anhydrase, Organophosphorus Acid
- Organophosphorus Acid Anhydrolase
- Acid Anhydrolase, Organophosphorus
- Anhydrolase, Organophosphorus Acid
- Organophosphorus Acid Hydrolase
- Acid Hydrolase, Organophosphorus
- Hydrolase, Organophosphorus Acid
- Organophosphorus Hydrolase
- Hydrolase, Organophosphorus
- Aryl-dialkyl Phosphatase
- Aryl dialkyl Phosphatase
- Phosphatase, Aryl-dialkyl
- OPH Enzyme
- Enzyme, OPH
|
Below are MeSH descriptors whose meaning is more general than "Aryldialkylphosphatase".
Below are MeSH descriptors whose meaning is more specific than "Aryldialkylphosphatase".
This graph shows the total number of publications written about "Aryldialkylphosphatase" by people in this website by year, and whether "Aryldialkylphosphatase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Aryldialkylphosphatase" by people in Profiles.
-
Ticagrelor induces paraoxonase-1 (PON1) and better protects hypercholesterolemic mice against atherosclerosis compared to clopidogrel. PLoS One. 2019; 14(6):e0218934.
-
Racial Differences in DNA-Methylation of CpG Sites Within Preterm-Promoting Genes and Gene Variants. Matern Child Health J. 2016 08; 20(8):1680-7.
-
Breaking the chain at the membrane: paraoxonase 2 counteracts lipid peroxidation at the plasma membrane. FASEB J. 2014 Apr; 28(4):1769-79.
-
Enhanced active metabolite generation and platelet inhibition with prasugrel compared to clopidogrel regardless of genotype in thienopyridine metabolic pathways. Thromb Haemost. 2013 Dec; 110(6):1223-31.
-
Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study. Ann Epidemiol. 2011 Nov; 21(11):815-23.
-
Structural insights into the dual activities of the nerve agent degrading organophosphate anhydrolase/prolidase. Biochemistry. 2010 Jan 26; 49(3):547-59.
-
Proteomic analysis of defined HDL subpopulations reveals particle-specific protein clusters: relevance to antioxidative function. Arterioscler Thromb Vasc Biol. 2009 Jun; 29(6):870-6.
-
Interaction effects of high-density lipoprotein metabolism gene variation and alcohol consumption on coronary heart disease risk: the atherosclerosis risk in communities study. J Stud Alcohol Drugs. 2007 Jul; 68(4):485-92.
-
Signaling mechanisms of down-regulation of voltage-activated Ca2+ channels by transient receptor potential vanilloid type 1 stimulation with olvanil in primary sensory neurons. Neuroscience. 2006 Aug 11; 141(1):407-19.
-
Q192R polymorphism of the paraoxanase 1 gene and its association with serum lipoprotein variables and carotid artery intima-media thickness in young adults from a biracial community. The Bogalusa Heart Study. Atherosclerosis. 2004 Nov; 177(1):167-74.