"Loperamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
| Descriptor ID |
D008139
|
| MeSH Number(s) |
D03.383.621.440
|
| Concept/Terms |
Loperamide Hydrochloride- Loperamide Hydrochloride
- Hydrochloride, Loperamide
- Loperamide Monohydrochloride
- Monohydrochloride, Loperamide
|
Below are MeSH descriptors whose meaning is more general than "Loperamide".
Below are MeSH descriptors whose meaning is more specific than "Loperamide".
This graph shows the total number of publications written about "Loperamide" by people in this website by year, and whether "Loperamide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Loperamide" by people in Profiles.
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Final findings from the CONTROL trial: Strategies to reduce the incidence and severity of neratinib-associated diarrhea in patients with HER2-positive early-stage breast cancer. Breast. 2023 Feb; 67:94-101.
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Controlling faecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomised clinical trial. Lancet Gastroenterol Hepatol. 2019 09; 4(9):698-710.
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Loperamide associated torsades de pointes, in the setting of complete heart block at marginally supratherapeutic dosing (20mg/day). Clin Toxicol (Phila). 2019 11; 57(11):1123-1124.
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Loperamide Mimicking Brugada Pattern. Methodist Debakey Cardiovasc J. 2018 Oct-Dec; 14(4):e1-e3.
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Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide. Clin Infect Dis. 2017 Nov 29; 65(12):2008-2017.
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Poor Man's Methadone: A Case Report of Loperamide Toxicity. Am J Forensic Med Pathol. 2015 Dec; 36(4):268-70.
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Loperamide Versus Psyllium Fiber for Treatment of Fecal Incontinence: The Fecal Incontinence Prescription (Rx) Management (FIRM) Randomized Clinical Trial. Dis Colon Rectum. 2015 Oct; 58(10):983-93.
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Loperamide therapy for voluminous diarrhea in Ebola virus disease. J Infect Dis. 2015 Apr 01; 211(7):1036-7.
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Acute infectious diarrhea in immunocompetent adults. N Engl J Med. 2014 Apr 17; 370(16):1532-40.
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Diabetic diarrhea. Curr Gastroenterol Rep. 2009 Oct; 11(5):354-9.