"Doxepin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
| Descriptor ID |
D004316
|
| MeSH Number(s) |
D02.355.291.852.500 D03.633.300.382.393
|
| Concept/Terms |
Doxepin Hydrochloride- Doxepin Hydrochloride
- Hydrochloride, Doxepin
- Doxepin Hydrochloride, Cis-Trans Isomer Mixture (approximately 1:5)
|
Below are MeSH descriptors whose meaning is more general than "Doxepin".
Below are MeSH descriptors whose meaning is more specific than "Doxepin".
This graph shows the total number of publications written about "Doxepin" by people in this website by year, and whether "Doxepin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Doxepin" by people in Profiles.
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Prescribing of psychotropics in the elderly: why is it so often inappropriate? CNS Drugs. 2002; 16(2):99-109.
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Doxepin therapy for postprandial symptomatic hypoglycaemic patients: neurochemical, hormonal and metabolic disturbances. Clin Sci (Lond). 1991 Apr; 80(4):373-84.
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Multiple-dose doxepin kinetics in depressed patients. Clin Pharmacol Ther. 1983 Oct; 34(4):509-15.