"Oxidopamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
| Descriptor ID |
D016627
|
| MeSH Number(s) |
D02.092.311.342.478.650
|
| Concept/Terms |
Oxidopamine- Oxidopamine
- 6-Hydroxydopamine
- 6 Hydroxydopamine
- 6-OHDA
|
Below are MeSH descriptors whose meaning is more general than "Oxidopamine".
Below are MeSH descriptors whose meaning is more specific than "Oxidopamine".
This graph shows the total number of publications written about "Oxidopamine" by people in this website by year, and whether "Oxidopamine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 3 | 3 |
| 1999 | 1 | 1 | 2 |
| 2000 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oxidopamine" by people in Profiles.
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Reduction of HIP2 expression causes motor function impairment and increased vulnerability to dopaminergic degeneration in Parkinson's disease models. Cell Death Dis. 2018 10 03; 9(10):1020.
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Spinal cord dopamine receptor expression and function in mice with 6-OHDA lesion of the A11 nucleus and dietary iron deprivation. J Neurosci Res. 2007 Apr; 85(5):1065-76.
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Neurotrophic effects of bone morphogenetic protein-7 in a rat model of Parkinson's disease. Brain Res. 2004 Oct 01; 1022(1-2):88-95.
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Survival of genetically engineered, adult-derived rat astrocytes grafted into the 6-hydroxydopamine lesioned adult rat striatum. Brain Res. 1999 Jan 16; 816(1):29-37.
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Overexpression of HA-Bax but not Bcl-2 or Bcl-XL attenuates 6-hydroxydopamine-induced neuronal apoptosis. Exp Neurol. 1998 Nov; 154(1):193-8.