"Clofazimine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
| Descriptor ID |
D002991
|
| MeSH Number(s) |
D03.633.300.704.353
|
| Concept/Terms |
Clofazimine- Clofazimine
- N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-((1-methylethyl)imino)-2-phenazinamine
|
Below are MeSH descriptors whose meaning is more general than "Clofazimine".
Below are MeSH descriptors whose meaning is more specific than "Clofazimine".
This graph shows the total number of publications written about "Clofazimine" by people in this website by year, and whether "Clofazimine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clofazimine" by people in Profiles.
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New Drugs and Regimens for Tuberculosis Disease Treatment in Children and Adolescents. J Pediatric Infect Dis Soc. 2022 Oct 31; 11(Supplement_3):S101-S109.
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Administration and monitoring of clofazimine for NTM infections in children with and without cystic fibrosis. J Cyst Fibros. 2022 03; 21(2):348-352.
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Bedaquiline-Resistant Tuberculosis: Dark Clouds on the Horizon. Am J Respir Crit Care Med. 2020 06 15; 201(12):1564-1568.
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Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis. Lancet Respir Med. 2020 04; 8(4):383-394.
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Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis. Lancet. 2018 09 08; 392(10150):821-834.
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Diffuse Lepromatous Leprosy Due to Mycobacterium lepromatosis in Quintana Roo, Mexico. J Clin Microbiol. 2015 Nov; 53(11):3695-8.
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Polychromatic corneal and conjunctival crystals secondary to clofazimine therapy in a leper. Ophthalmology. 1989 Mar; 96(3):311-5.