Connection

Co-Authors

This is a "connection" page, showing publications co-authored by RICHARD FINNELL and BOGDAN WLODARCZYK.
Connection Strength

8.562
  1. Gene Environment Interactions in the Etiology of Neural Tube Defects. Front Genet. 2021; 12:659612.
    View in: PubMed
    Score: 0.782
  2. Comparative teratogenicity analysis of valnoctamide, risperidone, and olanzapine in mice. Bipolar Disord. 2015 Sep; 17(6):615-25.
    View in: PubMed
    Score: 0.526
  3. Mthfr gene ablation enhances susceptibility to arsenic prenatal toxicity. Toxicol Appl Pharmacol. 2014 Feb 15; 275(1):22-7.
    View in: PubMed
    Score: 0.470
  4. Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate. Toxicol Lett. 2012 Dec 17; 215(3):214-8.
    View in: PubMed
    Score: 0.433
  5. Antiepileptic drugs and pregnancy outcomes. Am J Med Genet A. 2012 Aug; 158A(8):2071-90.
    View in: PubMed
    Score: 0.422
  6. Genetic basis of susceptibility to teratogen induced birth defects. Am J Med Genet C Semin Med Genet. 2011 Aug 15; 157C(3):215-26.
    View in: PubMed
    Score: 0.396
  7. Arsenic-induced gene expression changes in the neural tube of folate transport defective mouse embryos. Neurotoxicology. 2006 Jul; 27(4):547-57.
    View in: PubMed
    Score: 0.275
  8. Spontaneous neural tube defects in splotch mice supplemented with selected micronutrients. Toxicol Appl Pharmacol. 2006 May 15; 213(1):55-63.
    View in: PubMed
    Score: 0.266
  9. Linkage between Fuz and Gpr161 genes regulates sonic hedgehog signaling during mouse neural tube development. Development. 2024 Oct 01; 151(19).
    View in: PubMed
    Score: 0.247
  10. Disruption of Fuz in mouse embryos generates hypoplastic hindbrain development and reduced cranial nerve ganglia. Dev Dyn. 2024 Mar 19.
    View in: PubMed
    Score: 0.238
  11. The novel linkage between Fuz and Gpr161 genes regulates sonic hedgehog signaling during mouse embryonic development. bioRxiv. 2024 Jan 12.
    View in: PubMed
    Score: 0.235
  12. Disruption of Fuz in mouse embryos generates hypoplastic hindbrain development and reduced cranial nerve ganglia. bioRxiv. 2023 Aug 04.
    View in: PubMed
    Score: 0.228
  13. Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects. Front Cell Dev Biol. 2022; 10:832492.
    View in: PubMed
    Score: 0.206
  14. Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice. Toxicol Appl Pharmacol. 2001 Dec 15; 177(3):238-46.
    View in: PubMed
    Score: 0.204
  15. Wnt1 Lineage Specific Deletion of Gpr161 Results in Embryonic Midbrain Malformation and Failure of Craniofacial Skeletal Development. Front Genet. 2021; 12:761418.
    View in: PubMed
    Score: 0.203
  16. The interaction of maternal diabetes with mutations that affect folate metabolism and how they affect the development of neural tube defects in mice. Dev Dyn. 2019 10; 248(10):900-917.
    View in: PubMed
    Score: 0.174
  17. Dominant negative GPR161 rare variants are risk factors of human spina bifida. Hum Mol Genet. 2019 01 15; 28(2):200-208.
    View in: PubMed
    Score: 0.166
  18. Teratogenicity of valproic acid and its constitutional isomer, amide derivative valnoctamide in mice. Birth Defects Res. 2019 08 15; 111(14):1013-1023.
    View in: PubMed
    Score: 0.164
  19. Formate rescues neural tube defects caused by mutations in Slc25a32. Proc Natl Acad Sci U S A. 2018 05 01; 115(18):4690-4695.
    View in: PubMed
    Score: 0.158
  20. Arsenic-induced neural tube defects in mice: alterations in cell cycle gene expression. Reprod Toxicol. 1996 Nov-Dec; 10(6):447-54.
    View in: PubMed
    Score: 0.143
  21. Autism-Like Behavior and Epigenetic Changes Associated with Autism as Consequences of In Utero Exposure to Environmental Pollutants in a Mouse Model. Behav Neurol. 2015; 2015:426263.
    View in: PubMed
    Score: 0.133
  22. Transcriptional analyses of two mouse models of spina bifida. Birth Defects Res A Clin Mol Teratol. 2012 Oct; 94(10):782-9.
    View in: PubMed
    Score: 0.108
  23. Cannabinoid receptor 1 signaling in embryo neurodevelopment. Birth Defects Res B Dev Reprod Toxicol. 2012 Apr; 95(2):137-50.
    View in: PubMed
    Score: 0.103
  24. Teratogenic effects of antiepileptic drugs. Expert Rev Neurother. 2010 Jun; 10(6):943-59.
    View in: PubMed
    Score: 0.092
  25. The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol. 2009 Oct; 11(10):1225-32.
    View in: PubMed
    Score: 0.087
  26. Arsenate-induced maternal glucose intolerance and neural tube defects in a mouse model. Toxicol Appl Pharmacol. 2009 Aug 15; 239(1):29-36.
    View in: PubMed
    Score: 0.085
  27. Reproductive consequences of oral arsenate exposure during pregnancy in a mouse model. Birth Defects Res B Dev Reprod Toxicol. 2008 Feb; 83(1):40-7.
    View in: PubMed
    Score: 0.078
  28. Differentially expressed genes in embryonic cardiac tissues of mice lacking Folr1 gene activity. BMC Dev Biol. 2007 Nov 20; 7:128.
    View in: PubMed
    Score: 0.077
  29. Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube. Hum Mol Genet. 2008 Feb 15; 17(4):587-601.
    View in: PubMed
    Score: 0.077
  30. Cardiovascular abnormalities in Folr1 knockout mice and folate rescue. Birth Defects Res A Clin Mol Teratol. 2007 Apr; 79(4):257-68.
    View in: PubMed
    Score: 0.074
  31. Myo-inositol enhances teratogenicity of valproic acid in the mouse. Birth Defects Res A Clin Mol Teratol. 2006 Mar; 76(3):200-4.
    View in: PubMed
    Score: 0.068
  32. Role of Folbp1 in the regional regulation of apoptosis and cell proliferation in the developing neural tube and craniofacies. Am J Med Genet C Semin Med Genet. 2005 May 15; 135C(1):48-58.
    View in: PubMed
    Score: 0.065
  33. Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies. Toxicol Appl Pharmacol. 2005 Feb 15; 203(1):18-26.
    View in: PubMed
    Score: 0.063
  34. Developmental consequences of abnormal folate transport during murine heart morphogenesis. Birth Defects Res A Clin Mol Teratol. 2004 Jul; 70(7):449-58.
    View in: PubMed
    Score: 0.061
  35. Folate-regulated changes in gene expression in the anterior neural tube of folate binding protein-1 (Folbp1)-deficient murine embryos. Neurochem Res. 2004 Jun; 29(6):1105-12.
    View in: PubMed
    Score: 0.060
  36. Optical coherence tomography-guided Brillouin microscopy highlights regional tissue stiffness differences during anterior neural tube closure in the Mthfd1l murine mutant. Development. 2024 May 15; 151(10).
    View in: PubMed
    Score: 0.060
  37. Dolutegravir-induced neural tube defects in mice are folate responsive. AIDS. 2024 03 15; 38(4):439-446.
    View in: PubMed
    Score: 0.059
  38. Folate regulation of planar cell polarity pathway and F-actin through folate receptor alpha. FASEB J. 2024 01; 38(1):e23346.
    View in: PubMed
    Score: 0.059
  39. Excess folic acid intake increases DNA de novo point mutations. Cell Discov. 2023 Feb 28; 9(1):22.
    View in: PubMed
    Score: 0.055
  40. CIC missense variants contribute to susceptibility for spina bifida. Hum Mutat. 2022 12; 43(12):2021-2032.
    View in: PubMed
    Score: 0.054
  41. DNA methylation in Folbp1 knockout mice supplemented with folic acid during gestation. J Nutr. 2002 08; 132(8 Suppl):2457S-2461S.
    View in: PubMed
    Score: 0.053
  42. Somatic and de novo Germline Variants of MEDs in Human Neural Tube Defects. Front Cell Dev Biol. 2021; 9:641831.
    View in: PubMed
    Score: 0.048
  43. Identification and characterization of the human and mouse SLC19A3 gene: a novel member of the reduced folate family of micronutrient transporter genes. Mol Genet Metab. 2000 Dec; 71(4):581-90.
    View in: PubMed
    Score: 0.047
  44. FKBP8 variants are risk factors for spina bifida. Hum Mol Genet. 2020 11 04; 29(18):3132-3144.
    View in: PubMed
    Score: 0.047
  45. CIC de novo loss of function variants contribute to cerebral folate deficiency by downregulating FOLR1 expression. J Med Genet. 2021 07; 58(7):484-494.
    View in: PubMed
    Score: 0.046
  46. Valproic acid-induced alterations in growth and neurotrophic factor gene expression in murine embryos [corrected]. Reprod Toxicol. 2000 Jan-Feb; 14(1):1-11.
    View in: PubMed
    Score: 0.044
  47. Genetic basis of susceptibility to environmentally induced neural tube defects. Ann N Y Acad Sci. 2000; 919:261-77.
    View in: PubMed
    Score: 0.044
  48. Heritable spina bifida in sheep: A potential model for fetal repair of myelomeningocele. J Pediatr Surg. 2020 Mar; 55(3):475-481.
    View in: PubMed
    Score: 0.043
  49. Effect of stiripentol dose on phenytoin-induced teratogenesis in a mouse model. Reprod Toxicol. 1999 Mar-Apr; 13(2):85-91.
    View in: PubMed
    Score: 0.042
  50. Combining mouse embryonic stem cells and zebrafish embryos to evaluate developmental toxicity of chemical exposure. Reprod Toxicol. 2018 10; 81:220-228.
    View in: PubMed
    Score: 0.040
  51. Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. Biochem Mol Med. 1997 Apr; 60(2):81-91.
    View in: PubMed
    Score: 0.037
  52. Design and Comparative Evaluation of the Anticonvulsant Profile, Carbonic-Anhydrate Inhibition and Teratogenicity of Novel Carbamate Derivatives of Branched Aliphatic Carboxylic Acids with 4-Aminobenzensulfonamide. Neurochem Res. 2017 Jul; 42(7):1972-1982.
    View in: PubMed
    Score: 0.037
  53. Metabolite profiling of whole murine embryos reveals metabolic perturbations associated with maternal valproate-induced neural tube closure defects. Birth Defects Res. 2017 01 30; 109(2):106-119.
    View in: PubMed
    Score: 0.036
  54. Ultrasound-guided spectral photoacoustic imaging of hemoglobin oxygenation during development. Biomed Opt Express. 2017 Feb 01; 8(2):757-763.
    View in: PubMed
    Score: 0.036
  55. Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide--Amide derivatives of valproic acid. Epilepsy Behav. 2015 May; 46:72-8.
    View in: PubMed
    Score: 0.032
  56. Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid. Epilepsia. 2014 Dec; 55(12):1944-52.
    View in: PubMed
    Score: 0.031
  57. Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential. Epilepsia. 2014 Feb; 55(2):353-61.
    View in: PubMed
    Score: 0.029
  58. Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-Butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus. J Med Chem. 2013 Aug 22; 56(16):6467-77.
    View in: PubMed
    Score: 0.029
  59. Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes. Dev Cell. 2013 Jun 24; 25(6):623-35.
    View in: PubMed
    Score: 0.028
  60. The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system. FASEB J. 2013 Jun; 27(6):2468-75.
    View in: PubMed
    Score: 0.028
  61. C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice. J Immunol. 2013 Apr 01; 190(7):3493-9.
    View in: PubMed
    Score: 0.028
  62. Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid. Epilepsy Behav. 2011 Nov; 22(3):461-8.
    View in: PubMed
    Score: 0.025
  63. Fuz regulates craniofacial development through tissue specific responses to signaling factors. PLoS One. 2011; 6(9):e24608.
    View in: PubMed
    Score: 0.025
  64. Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia. J Invest Dermatol. 2011 Feb; 131(2):302-10.
    View in: PubMed
    Score: 0.024
  65. Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid. Epilepsia. 2010 Oct; 51(10):1944-53.
    View in: PubMed
    Score: 0.023
  66. Syntheses and evaluation of anticonvulsant profile and teratogenicity of novel amide derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide. J Med Chem. 2010 May 27; 53(10):4177-86.
    View in: PubMed
    Score: 0.023
  67. Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid. Neuropharmacology. 2010 Jun; 58(8):1228-36.
    View in: PubMed
    Score: 0.023
  68. Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative. Epilepsia. 2010 Mar; 51(3):323-32.
    View in: PubMed
    Score: 0.022
  69. Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid. J Med Chem. 2009 Apr 23; 52(8):2233-42.
    View in: PubMed
    Score: 0.021
  70. Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid. Epilepsia. 2008 Jul; 49(7):1202-12.
    View in: PubMed
    Score: 0.020
  71. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid. J Med Chem. 2007 Dec 13; 50(25):6419-27.
    View in: PubMed
    Score: 0.019
  72. Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide. Epilepsy Res. 2007 Jan; 73(1):75-84.
    View in: PubMed
    Score: 0.018
  73. Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug. Neuropharmacology. 2006 Sep; 51(4):933-46.
    View in: PubMed
    Score: 0.018
  74. 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. Cancer Res. 2006 Feb 15; 66(4):2459-67.
    View in: PubMed
    Score: 0.017
  75. Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice. Br J Pharmacol. 2003 Jun; 139(4):755-64.
    View in: PubMed
    Score: 0.014
  76. Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse. J Pharmacol Exp Ther. 1996 Dec; 279(3):1237-42.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.