FILIPPO G GIANCOTTI

TitleProfessor
InstitutionMD Anderson
DepartmentCancer Biology
Address1881 East Road
Houston TX 77054-3005
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Patel B, Zhou Y, Babcock RL, Ma F, Zal MA, Kumar D, Medik YB, Kahn LM, Pineda JE, Park EM, Schneider SM, Tang X, Raso MG, Jeter CR, Zal T, Clise-Dwyer K, Keyomarsi K, Giancotti FG, Colla S, Watowich SS. STAT3 protects hematopoietic stem cells by preventing activation of a deleterious autocrine type-I interferon response. Leukemia. 2024 Mar 11. PMID: 38467768.
      Citations:    Fields:    
    2. Bae SY, Chen Y, Chen H, Kumar D, Karaiskos S, Xu J, Lu C, Viny AD, Giancotti FG. Noncanonical Activity of Med4 as a Gatekeeper of Metastasis through Epigenetic Control of Integrin Signaling. bioRxiv. 2024 Jan 10. PMID: 38014033; PMCID: PMC10680920.
      Citations:    
    3. Kumar D, Gurrapu S, Wang Y, Bae SY, Pandey PR, Chen H, Mondal J, Han H, Wu CJ, Karaiskos S, Yang F, Sahin A, Wistuba II, Gao J, Tripathy D, Gao H, Izar B, Giancotti FG. LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells. Nat Cancer. 2024 Feb; 5(2):262-282. PMID: 38195932.
      Citations: 1     Fields:    Translation:AnimalsCells
    4. Kuburich NA, den Hollander P, Castaneda M, Pietil? M, Tang X, Batra H, Mart?nez-Pe?a F, Visal TH, Zhou T, Demestichas BR, Dontula RV, Liu JY, Maddela JJ, Padmanabhan RS, Phi LTH, Rosolen MJ, Sabapathy T, Kumar D, Giancotti FG, Lairson LL, Raso MG, Soundararajan R, Mani SA. Stabilizing vimentin phosphorylation inhibits stem-like cell properties and metastasis of hybrid epithelial/mesenchymal carcinomas. Cell Rep. 2023 12 26; 42(12):113470. PMID: 37979166.
      Citations: 1     Fields:    Translation:HumansCells
    5. Shin AE, Giancotti FG, Rustgi AK. Metastatic colorectal cancer: mechanisms and emerging therapeutics. Trends Pharmacol Sci. 2023 04; 44(4):222-236. PMID: 36828759; PMCID: PMC10365888.
      Citations:    
    6. Patel B, Zhou Y, Babcock RL, Ma F, Zal MA, Kumar D, Medik YB, Kahn LM, Pineda JE, Park EM, Tang X, Raso MG, Zal T, Clise-Dwyer K, Giancotti FG, Colla S, Watowich SS. STAT3 protects HSCs from intrinsic interferon signaling and loss of long-term blood-forming activity. bioRxiv. 2023 Feb 11. PMID: 36798265; PMCID: PMC9934695.
      Citations:    
    7. Meng Z, Li FL, Fang C, Yeoman B, Qiu Y, Wang Y, Cai X, Lin KC, Yang D, Luo M, Fu V, Ma X, Diao Y, Giancotti FG, Ren B, Engler AJ, Guan KL. The Hippo pathway mediates Semaphorin signaling. Sci Adv. 2022 May 27; 8(21):eabl9806. PMID: 35613278; PMCID: PMC9132450.
      Citations:    
    8. Han H, Wang Y, Curto J, Gurrapu S, Laudato S, Rumandla A, Chakraborty G, Wang X, Chen H, Jiang Y, Kumar D, Caggiano EG, Capogiri M, Zhang B, Ji Y, Maity SN, Hu M, Bai S, Aparicio AM, Efstathiou E, Logothetis CJ, Navin N, Navone NM, Chen Y, Giancotti FG. Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis. Cell Rep. 2022 04 05; 39(1):110595. PMID: 35385726; PMCID: PMC9414743.
      Citations:    Fields:    Translation:HumansAnimalsCells
    9. Karajannis MA, Mauguen A, Maloku E, Xu Q, Dunbar EM, Plotkin SR, Yaffee A, Wang S, Roland JT, Sen C, Placantonakis DG, Golfinos JG, Allen JC, Vitanza NA, Chiriboga LA, Schneider RJ, Deng J, Neubert TA, Goldberg JD, Zagzag D, Giancotti FG, Blakeley JO. Phase 0 Clinical Trial of Everolimus in Patients with Vestibular Schwannoma or Meningioma. Mol Cancer Ther. 2021 09; 20(9):1584-1591. PMID: 34224367; PMCID: PMC8419097.
      Citations: 1     Fields:    Translation:Humans
    10. Han H, Lee HH, Choi K, Moon YJ, Heo JE, Ham WS, Jang WS, Rha KH, Cho NH, Giancotti FG, Choi YD. Prostate epithelial genes define therapy-relevant prostate cancer molecular subtype. Prostate Cancer Prostatic Dis. 2021 12; 24(4):1080-1092. PMID: 33903734; PMCID: PMC8616761.
      Citations:    
    11. Cooper J, Xu Q, Zhou L, Pavlovic M, Ojeda V, Moulick K, de Stanchina E, Poirier JT, Zauderer M, Rudin CM, Karajannis MA, Hanemann CO, Giancotti FG. Correction: Combined Inhibition of NEDD8-activating Enzyme and mTOR Suppresses NF2 Loss-driven Tumorigenesis. Mol Cancer Ther. 2021 02; 20(2):450. PMID: 33547247.
      Citations:    Fields:    
    12. Chen G, Zhou H, Liu B, Wang Y, Zhao J, Giancotti FG, Long J. A heterotrimeric SMARCB1-SMARCC2 subcomplex is required for the assembly and tumor suppression function of the BAF chromatin-remodeling complex. Cell Discov. 2020; 6:66. PMID: 33024572; PMCID: PMC7506551.
      Citations:    
    13. Su W, Han HH, Wang Y, Zhang B, Zhou B, Cheng Y, Rumandla A, Gurrapu S, Chakraborty G, Su J, Yang G, Liang X, Wang G, Rosen N, Scher HI, Ouerfelli O, Giancotti FG. The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression. Cancer Cell. 2019 08 12; 36(2):139-155.e10. PMID: 31327655; PMCID: PMC7210785.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    14. Laudato S, Aparicio A, Giancotti FG. Clonal Evolution and Epithelial Plasticity in the Emergence of AR-Independent Prostate Carcinoma. Trends Cancer. 2019 07; 5(7):440-455. PMID: 31311658; PMCID: PMC6658113.
      Citations: 13     Fields:    Translation:HumansCells
    15. Jain N, Hartert K, Tadros S, Fiskus W, Havranek O, Ma MCJ, Bouska A, Heavican T, Kumar D, Deng Q, Moore D, Pak C, Liu CL, Gentles AJ, Kridel R, Smedby KE, Juliusson G, Rosenquist R, Gascoyne RD, Giancotti F, Neelapu SS, Westin J, Vose JM, Lunning MA, Greiner T, Rodig S, Iqbal J, Alizadeh AA, Davis RE, Bhalla K, Green MR, Hartmann E, Rosenwald A. Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma. Sci Transl Med. 2019 06 19; 11(497). PMID: 31217338; PMCID: PMC6724184.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    16. Okada T, Sinha S, Esposito I, Schiavon G, Su W, Pratilas CA, Abele C, Hernandez JM, Ohara M, Okada M, Viale A, Heguy A, Socci ND, Sapino A, Seshan VE, Long S, Inghirami G, Rosen N, Giancotti FG, L?pez-Lago MA. Author Correction: The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling. Nat Cell Biol. 2019 04; 21(4):534. PMID: 30842593.
      Citations: 5     Fields:    
    17. Cooper J, Giancotti FG. Integrin Signaling in Cancer: Mechanotransduction, Stemness, Epithelial Plasticity, and Therapeutic Resistance. Cancer Cell. 2019 03 18; 35(3):347-367. PMID: 30889378; PMCID: PMC6684107.
      Citations: 177     Fields:    Translation:HumansCells
    18. Er EE, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, Griscom B, Rosenblum M, Boire A, Brogi E, Giancotti FG, Schachner M, Malladi S, Massagu? J. Author Correction: Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol. 2019 Mar; 21(3):408. PMID: 30542103.
      Citations: 2     Fields:    
    19. Er EE, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, Griscom B, Rosenblum M, Boire A, Brogi E, Giancotti FG, Schachner M, Malladi S, Massagu? J. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol. 2018 08; 20(8):966-978. PMID: 30038252; PMCID: PMC6467203.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    20. Thompson BJ, Giancotti FG. Editorial overview: Cell signalling: Signal transduction to the nucleus, cytoskeleton, and organelles. Curr Opin Cell Biol. 2018 04; 51:iv-vii. PMID: 29753428.
      Citations:    
    21. Cooper J, Xu Q, Zhou L, Pavlovic M, Ojeda V, Moulick K, de Stanchina E, Poirier JT, Zauderer M, Rudin CM, Karajannis MA, Hanemann CO, Giancotti FG. Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis. Mol Cancer Ther. 2017 08; 16(8):1693-1704. PMID: 28468780; PMCID: PMC5929164.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    22. Cooper J, Giancotti FG. Cancer: a new role for non-canonical Hippo signaling. Cell Res. 2017 04; 27(4):459-460. PMID: 28244491; PMCID: PMC5385614.
      Citations: 2     Fields:    Translation:HumansCells
    23. Chen YB, Xu J, Skanderup AJ, Dong Y, Brannon AR, Wang L, Won HH, Wang PI, Nanjangud GJ, Jungbluth AA, Li W, Ojeda V, Hakimi AA, Voss MH, Schultz N, Motzer RJ, Russo P, Cheng EH, Giancotti FG, Lee W, Berger MF, Tickoo SK, Reuter VE, Hsieh JJ. Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets. Nat Commun. 2016 10 07; 7:13131. PMID: 27713405; PMCID: PMC5059781.
      Citations: 51     Fields:    Translation:HumansCells
    24. Gao H, Chakraborty G, Zhang Z, Akalay I, Gadiya M, Gao Y, Sinha S, Hu J, Jiang C, Akram M, Brogi E, Leitinger B, Giancotti FG. Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling. Cell. 2016 Jun 30; 166(1):47-62. PMID: 27368100; PMCID: PMC4980842.
      Citations: 105     Fields:    Translation:HumansAnimalsCells
    25. Garcia-Rendueles ME, Ricarte-Filho JC, Untch BR, Landa I, Knauf JA, Voza F, Smith VE, Ganly I, Taylor BS, Persaud Y, Oler G, Fang Y, Jhanwar SC, Heguy A, Giancotti F, Ghossein R, Fagin JA, Viale A, Huberman KH. NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition. Cancer Discov. 2015 Nov; 5(11):1178-93. PMID: 26359368; PMCID: PMC4642441.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    26. Giancotti FG, F?ssler R. Guido Tarone, Ph.D. (1951-2015). J Cell Sci. 2015 Aug 15; 128(16):2955-6. PMID: 26495456.
      Citations:    
    27. Giancotti FG, Haynes CM, Machesky LM, Olson MF, Overholtzer M. Alan Hall 1952-2015. Nat Cell Biol. 2015 Jul; 17(7):839-40. PMID: 26005836.
      Citations: 1     Fields:    
    28. Okada T, Sinha S, Esposito I, Schiavon G, Su W, Pratilas CA, Abele C, Hernandez JM, Ohara M, Okada M, Viale A, Heguy A, Socci ND, Sapino A, Seshan VE, Long S, Inghirami G, Rosen N, Giancotti FG, L?pez-Lago MA. The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling. Nat Cell Biol. 2015 Jan; 17(1):81-94. PMID: 25531777; PMCID: PMC4374353.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    29. Gao H, Chakraborty G, Lee-Lim AP, Mavrakis KJ, Wendel HG, Giancotti FG. Forward genetic screens in mice uncover mediators and suppressors of metastatic reactivation. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):16532-7. PMID: 25378704; PMCID: PMC4246349.
      Citations: 19     Fields:    Translation:AnimalsCells
    30. Li W, Cooper J, Zhou L, Yang C, Erdjument-Bromage H, Zagzag D, Snuderl M, Ladanyi M, Hanemann CO, Zhou P, Karajannis MA, Giancotti FG. Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus. Cancer Cell. 2014 Jul 14; 26(1):48-60. PMID: 25026211; PMCID: PMC4126592.
      Citations: 114     Fields:    Translation:HumansAnimalsCells
    31. Cooper J, Giancotti FG. Molecular insights into NF2/Merlin tumor suppressor function. FEBS Lett. 2014 Aug 19; 588(16):2743-52. PMID: 24726726; PMCID: PMC4111995.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    32. Heller BA, Ghidinelli M, Voelkl J, Einheber S, Smith R, Grund E, Morahan G, Chandler D, Kalaydjieva L, Giancotti F, King RH, Fejes-Toth AN, Fejes-Toth G, Feltri ML, Lang F, Salzer JL. Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system. J Cell Biol. 2014 Mar 31; 204(7):1219-36. PMID: 24687281; PMCID: PMC3971744.
      Citations:    
    33. Giancotti FG. Deregulation of cell signaling in cancer. FEBS Lett. 2014 Aug 19; 588(16):2558-70. PMID: 24561200; PMCID: PMC4111980.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    34. Karajannis MA, Hagiwara M, Giancotti FG, Filatov A, Derman A, Hochman T, Goldberg JD, Vega E, Wisoff JH, Golfinos JG, Merkelson A, Roland JT, Allen JC, Legault G. Phase II study of everolimus in children and adults with neurofibromatosis type 2 and progressive vestibular schwannomas. Neuro Oncol. 2014 Jan; 16(2):292-7. PMID: 24311643; PMCID: PMC3895376.
      Citations: 38     Fields:    Translation:HumansCTClinical Trials
    35. Giancotti FG. Mechanisms governing metastatic dormancy and reactivation. Cell. 2013 Nov 07; 155(4):750-64. PMID: 24209616; PMCID: PMC4354734.
      Citations: 238     Fields:    Translation:HumansAnimalsCells
    36. Yoshioka T, Otero J, Chen Y, Kim YM, Koutcher JA, Satagopan J, Reuter V, Carver B, de Stanchina E, Enomoto K, Greenberg NM, Scardino PT, Scher HI, Sawyers CL, Giancotti FG. ?4 Integrin signaling induces expansion of prostate tumor progenitors. J Clin Invest. 2013 Feb; 123(2):682-99. PMID: 23348745; PMCID: PMC3561800.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    37. Gao H, Chakraborty G, Lee-Lim AP, Mo Q, Decker M, Vonica A, Shen R, Brogi E, Brivanlou AH, Giancotti FG. The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites. Cell. 2012 Aug 17; 150(4):764-79. PMID: 22901808; PMCID: PMC3711709.
      Citations: 198     Fields:    Translation:HumansAnimalsCells
    38. Ladanyi M, Zauderer MG, Krug LM, Ito T, McMillan R, Bott M, Giancotti F. New strategies in pleural mesothelioma: BAP1 and NF2 as novel targets for therapeutic development and risk assessment. Clin Cancer Res. 2012 Sep 01; 18(17):4485-90. PMID: 22825583; PMCID: PMC3432735.
      Citations: 29     Fields:    Translation:Humans
    39. Cooper J, Karajannis MA, Giancotti FG, Li W. Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus. EMBO Rep. 2012 Mar; 13(3):204-15. PMID: 22482125; PMCID: PMC3323126.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    40. Acosta MT, Babovic-Vuksanovic D, Carpen O, Cichowski K, Evans DG, Giancotti F, Hanemann CO, Ingram D, Lloyd AC, Mayes DA, Messiaen L, Morrison H, North K, Packer R, Pan D, Stemmer-Rachamimov A, Upadhyaya M, Viskochil D, Wallace MR, Hunter-Schaedle K, Ratner N, Kalamarides M. Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting. Acta Neuropathol. 2012 Mar; 123(3):369-80. PMID: 22083253; PMCID: PMC3282898.
      Citations: 10     Fields:    Translation:Humans
    41. Baranwal S, Wang Y, Rathinam R, Lee J, Jin L, McGoey R, Pylayeva Y, Giancotti F, Blobe GC, Alahari SK. Molecular characterization of the tumor-suppressive function of nischarin in breast cancer. J Natl Cancer Inst. 2011 Oct 19; 103(20):1513-28. PMID: 21917605; PMCID: PMC3196482.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    42. Cooper J, Li W, You L, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG. Merlin/NF2 functions upstream of the nuclear E3 ubiquitin ligase CRL4DCAF1 to suppress oncogenic gene expression. Sci Signal. 2011 Aug 23; 4(188):pt6. PMID: 21878678.
      Citations: 16     Fields:    Translation:AnimalsCells
    43. Fan J, Cai B, Zeng M, Hao Y, Giancotti FG, Fu BM. Integrin ?4 signaling promotes mammary tumor cell adhesion to brain microvascular endothelium by inducing ErbB2-mediated secretion of VEGF. Ann Biomed Eng. 2011 Aug; 39(8):2223-2241. PMID: 21556948; PMCID: PMC4406420.
      Citations: 27     Fields:    Translation:AnimalsCells
    44. Huson SM, Acosta MT, Belzberg AJ, Bernards A, Chernoff J, Cichowski K, Gareth Evans D, Ferner RE, Giovannini M, Korf BR, Listernick R, North KN, Packer RJ, Parada LF, Peltonen J, Ramesh V, Reilly KM, Risner JW, Schorry EK, Upadhyaya M, Viskochil DH, Zhu Y, Hunter-Schaedle K, Giancotti FG. Back to the future: proceedings from the 2010 NF Conference. Am J Med Genet A. 2011 Feb; 155A(2):307-21. PMID: 21271647; PMCID: PMC3079924.
      Citations:    
    45. Li W, Giancotti FG. Merlin's tumor suppression linked to inhibition of the E3 ubiquitin ligase CRL4 (DCAF1). Cell Cycle. 2010 Nov 15; 9(22):4433-6. PMID: 21084862; PMCID: PMC3048042.
      Citations: 9     Fields:    Translation:AnimalsCells
    46. Rossi F, Yozgat Y, de Stanchina E, Veach D, Clarkson B, Manova K, Giancotti FG, Antonescu CR, Besmer P. Imatinib upregulates compensatory integrin signaling in a mouse model of gastrointestinal stromal tumor and is more effective when combined with dasatinib. Mol Cancer Res. 2010 Sep; 8(9):1271-83. PMID: 20736294; PMCID: PMC2952175.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    47. Li W, You L, Cooper J, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG. Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus. Cell. 2010 Feb 19; 140(4):477-90. PMID: 20178741; PMCID: PMC2828953.
      Citations: 171     Fields:    Translation:HumansAnimalsCells
    48. Ammoun S, Cunliffe CH, Allen JC, Chiriboga L, Giancotti FG, Zagzag D, Hanemann CO, Karajannis MA. ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma. Neuro Oncol. 2010 Aug; 12(8):834-43. PMID: 20511180; PMCID: PMC2940674.
      Citations: 42     Fields:    Translation:HumansCells
    49. Shen S, Fan J, Cai B, Lv Y, Zeng M, Hao Y, Giancotti FG, Fu BM. Vascular endothelial growth factor enhances cancer cell adhesion to microvascular endothelium in vivo. Exp Physiol. 2010 Feb; 95(2):369-79. PMID: 19880535; PMCID: PMC2859456.
      Citations:    
    50. Okada T, Murillo MM, Socci N, Giancotti FG, L?pez-Lago MA. Loss of the tumor suppressor gene NF2, encoding merlin, constitutively activates integrin-dependent mTORC1 signaling. Mol Cell Biol. 2009 Aug; 29(15):4235-49. PMID: 19451229; PMCID: PMC2715795.
      Citations: 78     Fields:    Translation:HumansCells
    51. Pylayeva Y, Gillen KM, Gerald W, Beggs HE, Reichardt LF, Giancotti FG. Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling. J Clin Invest. 2009 Feb; 119(2):252-66. PMID: 19147981; PMCID: PMC2631302.
      Citations: 145     Fields:    Translation:HumansAnimalsCells
    52. Roberts JE, Nikolopoulos SN, Oktem O, Giancotti F, Oktay K. Integrin beta-4 signaling plays a key role in mouse embryogenesis. Reprod Sci. 2009 Mar; 16(3):286-93. PMID: 19087978.
      Citations:    
    53. Oktay K, Buyuk E, Oktem O, Oktay M, Giancotti FG. The c-Jun N-terminal kinase JNK functions upstream of Aurora B to promote entry into mitosis. Cell Cycle. 2008 Feb 15; 7(4):533-41. PMID: 18431843.
      Citations:    
    54. Giancotti FG. Targeting integrin beta4 for cancer and anti-angiogenic therapy. Trends Pharmacol Sci. 2007 Oct; 28(10):506-11. PMID: 17822782.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    55. Pylayeva Y, Giancotti FG. Tensin relief facilitates migration. Nat Cell Biol. 2007 Aug; 9(8):877-9. PMID: 17671456.
      Citations:    
    56. Okada T, You L, Giancotti FG. Shedding light on Merlin's wizardry. Trends Cell Biol. 2007 May; 17(5):222-9. PMID: 17442573.
      Citations: 52     Fields:    Translation:HumansAnimals
    57. Pylayeva Y, Guo W, Giancotti FG. Analysis of integrin signaling in genetically engineered mouse models of mammary tumor progression. Methods Enzymol. 2007; 426:439-61. PMID: 17697895.
      Citations: 3     Fields:    Translation:AnimalsCells
    58. Guo W, Pylayeva Y, Pepe A, Yoshioka T, Muller WJ, Inghirami G, Giancotti FG. Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis. Cell. 2006 Aug 11; 126(3):489-502. PMID: 16901783.
      Citations: 237     Fields:    Translation:AnimalsCells
    59. Pylayeva Y, Giancotti FG. Development requires activation but not phosphorylation of beta1 integrins. Genes Dev. 2006 May 01; 20(9):1057-60. PMID: 16651652.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    60. Okada T, Lopez-Lago M, Giancotti FG. Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane. J Cell Biol. 2005 Oct 24; 171(2):361-71. PMID: 16247032; PMCID: PMC2171182.
      Citations: 87     Fields:    Translation:HumansCells
    61. Nikolopoulos SN, Blaikie P, Yoshioka T, Guo W, Puri C, Tacchetti C, Giancotti FG. Targeted deletion of the integrin beta4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-kappaB, causing defects in epidermal growth and migration. Mol Cell Biol. 2005 Jul; 25(14):6090-102. PMID: 15988021; PMCID: PMC1168825.
      Citations: 53     Fields:    Translation:AnimalsCells
    62. Vidal A, Zacharoulis S, Guo W, Shaffer D, Giancotti F, Bramley AH, de la Hoz C, Jensen KK, Kato D, MacDonald DD, Knowles J, Yeh N, Frohman LA, Rafii S, Lyden D, Koff A. p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow. Proc Natl Acad Sci U S A. 2005 May 10; 102(19):6890-5. PMID: 15867156; PMCID: PMC1088064.
      Citations: 9     Fields:    Translation:AnimalsCells
    63. Nikolopoulos SN, Giancotti FG. Netrin-integrin signaling in epithelial morphogenesis, axon guidance and vascular patterning. Cell Cycle. 2005 Mar; 4(3):e131-5. PMID: 15725728.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    64. Nikolopoulos SN, Blaikie P, Yoshioka T, Guo W, Giancotti FG. Integrin beta4 signaling promotes tumor angiogenesis. Cancer Cell. 2004 Nov; 6(5):471-83. PMID: 15542431.
      Citations: 100     Fields:    Translation:HumansAnimalsCells
    65. Guo W, Giancotti FG. Integrin signalling during tumour progression. Nat Rev Mol Cell Biol. 2004 Oct; 5(10):816-26. PMID: 15459662.
      Citations: 570     Fields:    Translation:Cells
    66. Gagnoux-Palacios L, Dans M, van't Hof W, Mariotti A, Pepe A, Meneguzzi G, Resh MD, Giancotti FG. Compartmentalization of integrin alpha6beta4 signaling in lipid rafts. J Cell Biol. 2003 Sep 29; 162(7):1189-96. PMID: 14517202; PMCID: PMC2173954.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    67. Giancotti FG. A structural view of integrin activation and signaling. Dev Cell. 2003 Feb; 4(2):149-51. PMID: 12586058.
      Citations: 24     Fields:    Translation:HumansCells
    68. Giancotti FG, Tarone G. Positional control of cell fate through joint integrin/receptor protein kinase signaling. Annu Rev Cell Dev Biol. 2003; 19:173-206. PMID: 14570568.
      Citations: 155     Fields:    Translation:HumansAnimalsCells
    69. Klein S, de Fougerolles AR, Blaikie P, Khan L, Pepe A, Green CD, Koteliansky V, Giancotti FG. Alpha 5 beta 1 integrin activates an NF-kappa B-dependent program of gene expression important for angiogenesis and inflammation. Mol Cell Biol. 2002 Aug; 22(16):5912-22. PMID: 12138201; PMCID: PMC133962.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    70. Barberis L, Brancaccio M, Azzolino O, Xu D, Kyriakis JM, Silengo L, Giancotti FG, Tarone G, Altruda F, Hirsch E, F?ssler R. Defective Rac-mediated proliferation and survival after targeted mutation of the beta1 integrin cytodomain. J Cell Biol. 2002 Apr 29; 157(3):481-92. PMID: 11980921; PMCID: PMC2173276.
      Citations: 27     Fields:    Translation:AnimalsCells
    71. Dans M, Gagnoux-Palacios L, Blaikie P, Klein S, Mariotti A, Giancotti FG. Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes. J Biol Chem. 2001 Jan 12; 276(2):1494-502. PMID: 11044453.
      Citations: 62     Fields:    Translation:HumansCells
    72. Sumitomo M, Shen R, Walburg M, Dai J, Geng Y, Navarro D, Boileau G, Papandreou CN, Giancotti FG, Knudsen B, Nanus DM. Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling. J Clin Invest. 2000 Dec; 106(11):1399-407. PMID: 11104793; PMCID: PMC381465.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    73. Barberis L, Wary KK, Fiucci G, Liu F, Hirsch E, Brancaccio M, Altruda F, Tarone G, Giancotti FG. Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK. J Biol Chem. 2000 Nov 24; 275(47):36532-40. PMID: 10976102.
      Citations: 35     Fields:    Translation:AnimalsCells
    74. Bhol KC, Dans MJ, Simmons RK, Foster CS, Giancotti FG, Ahmed AR. The autoantibodies to alpha 6 beta 4 integrin of patients affected by ocular cicatricial pemphigoid recognize predominantly epitopes within the large cytoplasmic domain of human beta 4. J Immunol. 2000 Sep 01; 165(5):2824-9. PMID: 10946315.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    75. Giancotti FG. Complexity and specificity of integrin signalling. Nat Cell Biol. 2000 Jan; 2(1):E13-4. PMID: 10620816.
      Citations: 66     Fields:    Translation:HumansCells
    76. Giancotti FG, Ruoslahti E. Integrin signaling. Science. 1999 Aug 13; 285(5430):1028-32. PMID: 10446041.
      Citations: 1201     Fields:    Translation:HumansAnimalsCells
    77. Oktay M, Wary KK, Dans M, Birge RB, Giancotti FG. Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle. J Cell Biol. 1999 Jun 28; 145(7):1461-9. PMID: 10385525; PMCID: PMC2133163.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    78. Wary KK, Dans M, Mariotti A, Giancotti FG. Biochemical analysis of integrin-mediated Shc signaling. Methods Mol Biol. 1999; 129:35-49. PMID: 10494556.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    79. Oktay MH, Mariotti A, Giancotti FG. Assays for kinase activity. Methods Mol Biol. 1999; 129:51-61. PMID: 10494557.
      Citations:    Fields:    Translation:HumansAnimalsCells
    80. Lora JM, Rowader KE, Soares L, Giancotti F, Zaret KS. Alpha3beta1-integrin as a critical mediator of the hepatic differentiation response to the extracellular matrix. Hepatology. 1998 Oct; 28(4):1095-104. PMID: 9755248.
      Citations: 10     Fields:    Translation:AnimalsCells
    81. Wary KK, Mariotti A, Zurzolo C, Giancotti FG. A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell. 1998 Sep 04; 94(5):625-34. PMID: 9741627.
      Citations: 192     Fields:    Translation:AnimalsCells
    82. Munger JS, Harpel JG, Giancotti FG, Rifkin DB. Interactions between growth factors and integrins: latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1. Mol Biol Cell. 1998 Sep; 9(9):2627-38. PMID: 9725916; PMCID: PMC25536.
      Citations: 100     Fields:    Translation:HumansCells
    83. Pozzi A, Wary KK, Giancotti FG, Gardner HA. Integrin alpha1beta1 mediates a unique collagen-dependent proliferation pathway in vivo. J Cell Biol. 1998 Jul 27; 142(2):587-94. PMID: 9679154; PMCID: PMC2133043.
      Citations: 80     Fields:    Translation:AnimalsCells
    84. Murgia C, Blaikie P, Kim N, Dans M, Petrie HT, Giancotti FG. Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain. EMBO J. 1998 Jul 15; 17(14):3940-51. PMID: 9670011; PMCID: PMC1170729.
      Citations: 41     Fields:    Translation:AnimalsCells
    85. Ioachim HL, Antonescu C, Giancotti F, Dorsett B. EBV-associated primary lymphomas in salivary glands of HIV-infected patients. Pathol Res Pract. 1998; 194(2):87-95. PMID: 9584321.
      Citations: 3     Fields:    Translation:HumansCells
    86. Sanders RJ, Mainiero F, Giancotti FG. The role of integrins in tumorigenesis and metastasis. Cancer Invest. 1998; 16(5):329-44. PMID: 9627681.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    87. Giancotti FG. Integrin signaling: specificity and control of cell survival and cell cycle progression. Curr Opin Cell Biol. 1997 Oct; 9(5):691-700. PMID: 9330873.
      Citations: 100     Fields:    Translation:AnimalsCells
    88. Ioachim HL, Antonescu C, Giancotti F, Dorsett B, Weinstein MA. EBV-associated anorectal lymphomas in patients with acquired immune deficiency syndrome. Am J Surg Pathol. 1997 Sep; 21(9):997-1006. PMID: 9298875.
      Citations: 8     Fields:    Translation:HumansCells
    89. Mainiero F, Murgia C, Wary KK, Curatola AM, Pepe A, Blumemberg M, Westwick JK, Der CJ, Giancotti FG. The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation. EMBO J. 1997 May 01; 16(9):2365-75. PMID: 9171350; PMCID: PMC1169837.
      Citations: 84     Fields:    Translation:HumansAnimalsCells
    90. Wary KK, Mainiero F, Isakoff SJ, Marcantonio EE, Giancotti FG. The adaptor protein Shc couples a class of integrins to the control of cell cycle progression. Cell. 1996 Nov 15; 87(4):733-43. PMID: 8929541.
      Citations: 174     Fields:    Translation:AnimalsCells
    91. Jones J, Sugiyama M, Giancotti F, Speight PM, Watt FM. Transfection of beta 4 integrin subunit into a neoplastic keratinocyte line fails to restore terminal differentiation capacity or influence proliferation. Cell Adhes Commun. 1996 Nov; 4(4-5):307-16. PMID: 9117349.
      Citations: 3     Fields:    
    92. Klein S, Bikfalvi A, Birkenmeier TM, Giancotti FG, Rifkin DB. Integrin regulation by endogenous expression of 18-kDa fibroblast growth factor-2. J Biol Chem. 1996 Sep 13; 271(37):22583-90. PMID: 8798427.
      Citations: 12     Fields:    Translation:AnimalsCells
    93. Mainiero F, Pepe A, Yeon M, Ren Y, Giancotti FG. The intracellular functions of alpha6beta4 integrin are regulated by EGF. J Cell Biol. 1996 Jul; 134(1):241-53. PMID: 8698818; PMCID: PMC2120929.
      Citations: 59     Fields:    Translation:HumansCells
    94. Giancotti FG. Signal transduction by the alpha 6 beta 4 integrin: charting the path between laminin binding and nuclear events. J Cell Sci. 1996 Jun; 109 ( Pt 6):1165-72. PMID: 8799807.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    95. Mainiero F, Pepe A, Wary KK, Spinardi L, Mohammadi M, Schlessinger J, Giancotti FG. Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes. EMBO J. 1995 Sep 15; 14(18):4470-81. PMID: 7556090; PMCID: PMC394539.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    96. Spinardi L, Einheber S, Cullen T, Milner TA, Giancotti FG. A recombinant tail-less integrin beta 4 subunit disrupts hemidesmosomes, but does not suppress alpha 6 beta 4-mediated cell adhesion to laminins. J Cell Biol. 1995 Apr; 129(2):473-87. PMID: 7721947; PMCID: PMC2199916.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    97. Giancotti FG, Mainiero F. Integrin-mediated adhesion and signaling in tumorigenesis. Biochim Biophys Acta. 1994 May 27; 1198(1):47-64. PMID: 8199195.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    98. Thompson KA, Wang B, Argraves WS, Giancotti FG, Schranck DP, Ruoslahti E. BR140, a novel zinc-finger protein with homology to the TAF250 subunit of TFIID. Biochem Biophys Res Commun. 1994 Feb 15; 198(3):1143-52. PMID: 7906940.
      Citations: 18     Fields:    Translation:HumansCells
    99. Ioachim HL, Pambuccian S, Giancotti F, Dorsett B. Reactivity of lung tumors with lung-derived and non-lung-derived monoclonal antibodies. Int J Cancer Suppl. 1994; 8:132-3. PMID: 7515026.
      Citations:    Fields:    Translation:Humans
    100. Giancotti FG, Spinardi L, Mainiero F, Sanders R. Expression of heterologous integrin genes in cultured eukaryotic cells. Methods Enzymol. 1994; 245:297-316. PMID: 7760740.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    101. Einheber S, Milner TA, Giancotti F, Salzer JL. Axonal regulation of Schwann cell integrin expression suggests a role for alpha 6 beta 4 in myelination. J Cell Biol. 1993 Dec; 123(5):1223-36. PMID: 8245127; PMCID: PMC2119881.
      Citations: 68     Fields:    Translation:AnimalsCells
    102. Klein S, Giancotti FG, Presta M, Albelda SM, Buck CA, Rifkin DB. Basic fibroblast growth factor modulates integrin expression in microvascular endothelial cells. Mol Biol Cell. 1993 Oct; 4(10):973-82. PMID: 8298194; PMCID: PMC275731.
      Citations: 40     Fields:    Translation:AnimalsCells
    103. Spinardi L, Ren YL, Sanders R, Giancotti FG. The beta 4 subunit cytoplasmic domain mediates the interaction of alpha 6 beta 4 integrin with the cytoskeleton of hemidesmosomes. Mol Biol Cell. 1993 Sep; 4(9):871-84. PMID: 8257791; PMCID: PMC275718.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    104. Perticone F, Ceravolo R, Maio R, Cosco C, Giancotti F, Mattioli PL. [Mechano-electric feedback and ventricular arrhythmias in heart failure. The possible role of permanent cardiac stimulation in preventing ventricular tachycardia]. Cardiologia. 1993 Apr; 38(4):247-52. PMID: 8343941.
      Citations:    Fields:    Translation:Humans
    105. Giancotti FG, Stepp MA, Suzuki S, Engvall E, Ruoslahti E. Proteolytic processing of endogenous and recombinant beta 4 integrin subunit. J Cell Biol. 1992 Aug; 118(4):951-9. PMID: 1500432; PMCID: PMC2289563.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    106. Bauer JS, Schreiner CL, Giancotti FG, Ruoslahti E, Juliano RL. Motility of fibronectin receptor-deficient cells on fibronectin and vitronectin: collaborative interactions among integrins. J Cell Biol. 1992 Jan; 116(2):477-87. PMID: 1370495; PMCID: PMC2289293.
      Citations: 43     Fields:    Translation:AnimalsCells
    107. Rossino P, Gavazzi I, Timpl R, Aumailley M, Abbadini M, Giancotti F, Silengo L, Marchisio PC, Tarone G. Nerve growth factor induces increased expression of a laminin-binding integrin in rat pheochromocytoma PC12 cells. Exp Cell Res. 1990 Jul; 189(1):100-8. PMID: 2140793.
      Citations: 18     Fields:    Translation:AnimalsCells
    108. Vogel BE, Tarone G, Giancotti FG, Gailit J, Ruoslahti E. A novel fibronectin receptor with an unexpected subunit composition (alpha v beta 1). J Biol Chem. 1990 Apr 15; 265(11):5934-7. PMID: 2138612.
      Citations: 87     Fields:    Translation:HumansCells
    109. Giancotti FG, Ruoslahti E. Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells. Cell. 1990 Mar 09; 60(5):849-59. PMID: 2155708.
      Citations: 198     Fields:    Translation:HumansAnimalsCells
    110. Altruda F, Cervella P, Gaeta ML, Daniele A, Giancotti F, Tarone G, Stefanuto G, Silengo L. Cloning of cDNA for a novel mouse membrane glycoprotein (gp42): shared identity to histocompatibility antigens, immunoglobulins and neural-cell adhesion molecules. Gene. 1989 Dec 28; 85(2):445-51. PMID: 2697642.
      Citations: 21     Fields:    Translation:AnimalsCells
    111. Ruoslahti E, Giancotti FG. Integrins and tumor cell dissemination. Cancer Cells. 1989 Dec; 1(4):119-26. PMID: 2701367.
      Citations: 77     Fields:    Translation:Humans
    112. Conforti G, Zanetti A, Colella S, Abbadini M, Marchisio PC, Pytela R, Giancotti F, Tarone G, Languino LR, Dejana E. Interaction of fibronectin with cultured human endothelial cells: characterization of the specific receptor. Blood. 1989 May 01; 73(6):1576-85. PMID: 2469496.
      Citations: 21     Fields:    Translation:HumansCells
    113. Bretti S, Neri P, Lozzi L, Rustici M, Comoglio P, Giancotti F, Tarone G. Inhibition of experimental metastasis of murine fibrosarcoma cells by oligopeptide analogues to the fibronectin cell-binding site. Int J Cancer. 1989 Jan 15; 43(1):102-6. PMID: 2521334.
      Citations: 2     Fields:    Translation:AnimalsCells
    114. Marchisio PC, D'Urso N, Comoglio PM, Giancotti FG, Tarone G. Vanadate-treated baby hamster kidney fibroblasts show cytoskeleton and adhesion patterns similar to their Rous sarcoma virus-transformed counterparts. J Cell Biochem. 1988 Jun; 37(2):151-9. PMID: 2456294.
      Citations: 7     Fields:    Translation:AnimalsCells
    115. Tarone G, Mascarello P, Zibetti M, Giancotti FG. Purification of the beta subunit of the fibronectin receptor. Eur J Biochem. 1988 Mar 15; 172(3):713-8. PMID: 2965011.
      Citations:    Fields:    Translation:AnimalsCells
    116. Albini A, Allavena G, Melchiori A, Giancotti F, Richter H, Comoglio PM, Parodi S, Martin GR, Tarone G. Chemotaxis of 3T3 and SV3T3 cells to fibronectin is mediated through the cell-attachment site in fibronectin and a fibronectin cell surface receptor. J Cell Biol. 1987 Oct; 105(4):1867-72. PMID: 2959668; PMCID: PMC2114639.
      Citations: 12     Fields:    Translation:AnimalsCells
    117. Giancotti FG, Languino LR, Zanetti A, Peri G, Tarone G, Dejana E. Platelets express a membrane protein complex immunologically related to the fibroblast fibronectin receptor and distinct from GPIIb/IIIa. Blood. 1987 May; 69(5):1535-8. PMID: 2952186.
      Citations: 4     Fields:    Translation:HumansCells
    118. Giancotti FG, Comoglio PM, Tarone G. Interaction of fibroblasts, hemopoietic cells and platelets with extracellular matrix: characterization and role of a common cell surface glycoprotein. Ann N Y Acad Sci. 1987; 511:65-76. PMID: 3439719.
      Citations:    Fields:    Translation:HumansAnimalsCells
    119. Giancotti FG, Comoglio PM, Tarone G. Fibronectin-plasma membrane interaction in the adhesion of hemopoietic cells. J Cell Biol. 1986 Aug; 103(2):429-37. PMID: 2942550; PMCID: PMC2113842.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    120. Giancotti FG, Comoglio PM, Tarone G. A 135,000 molecular weight plasma membrane glycoprotein involved in fibronectin-mediated cell adhesion. Immunofluorescence localization in normal and RSV-transformed fibroblasts. Exp Cell Res. 1986 Mar; 163(1):47-62. PMID: 3002832.
      Citations: 19     Fields:    Translation:AnimalsCells
    121. Tarone G, Cirillo D, Giancotti FG, Comoglio PM, Marchisio PC. Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes. Exp Cell Res. 1985 Jul; 159(1):141-57. PMID: 2411576.
      Citations: 167     Fields:    Translation:AnimalsCells
    122. Giancotti FG, Tarone G, Knudsen K, Damsky C, Comoglio PM. Cleavage of a 135 kD cell surface glycoprotein correlates with loss of fibroblast adhesion to fibronectin. Exp Cell Res. 1985 Jan; 156(1):182-90. PMID: 2981173.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    123. Comoglio PM, Di Renzo MF, Tarone G, Giancotti FG, Naldini L, Marchisio PC. Detection of phosphotyrosine-containing proteins in the detergent-insoluble fraction of RSV-transformed fibroblasts by azobenzene phosphonate antibodies. EMBO J. 1984 Mar; 3(3):483-9. PMID: 6201361; PMCID: PMC557374.
      Citations: 34     Fields:    Translation:AnimalsCells
    124. Effects of integrin signaling on mammary tumor cells adhesion to microvascular endothelium in vivo. 175-176.
    125. Expression of fibronectin receptor activity on immature hemopoietic cells. Cell Biology International Reports. 10:173.
    126. Erratum. EMBO Journal. 19:5585.
    127. Effects of VEGF on adhesion of mammary carcinoma cells to brain microvascular endothelium.
    128. RSV transformed fibroblasts and monocytes share peculiar adhesion sites. Cell Biology International Reports. 10:161.
    129. Erratum. Molecular and Cellular Biology. 25:7926.
    130. Integrin expression in the developing mouse retina. Investigative Ophthalmology and Visual Science. 37.
    131. NF2 loss promotes oncogenic RAS-induced thyroid cancers via YAP-dependent transactivation of RAS proteins and sensitizes them to MEK inhibition. Cancer Discovery. 5:1178-1193.
    132. Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets. Nature Communications. 7.
    133. Merlin. EMBO Reports.
    134. Do cell cycle inhibitors promote angiogenesis by altering the bone marrow microenvironment?. Cancer Biology and Therapy. 4.
    135. Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling. Cell. 166:47-62.
    136. EGF-R signaling through Fyn kinase disrupts the function of integrin α6β4 at hemidesmosomes. Journal of Cell Biology. 155:447-457.
    137. The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling. Nature Cell Biology. 17:81-94.
    138. The adapter protein. Kidney International. 56:1189.
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