FILIPPO G GIANCOTTI

TitleProfessor
InstitutionMD Anderson
DepartmentCancer Biology
Address1881 East Road
Houston TX 77054-3005
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Karajannis MA, Mauguen A, Maloku E, Xu Q, Dunbar EM, Plotkin SR, Yaffee A, Wang S, Roland JT, Sen C, Placantonakis DG, Golfinos JG, Allen JC, Vitanza NA, Chiriboga LA, Schneider RJ, Deng J, Neubert TA, Goldberg JD, Zagzag D, Giancotti FG, Blakeley JO. Phase 0 Clinical Trial of Everolimus in Patients with Vestibular Schwannoma or Meningioma. Mol Cancer Ther. 2021 Sep; 20(9):1584-1591. PMID: 34224367.
      Citations:    Fields:    
    2. Cooper J, Xu Q, Zhou L, Pavlovic M, Ojeda V, Moulick K, de Stanchina E, Poirier JT, Zauderer M, Rudin CM, Karajannis MA, Hanemann CO, Giancotti FG. Correction: Combined Inhibition of NEDD8-activating Enzyme and mTOR Suppresses NF2 Loss-driven Tumorigenesis. Mol Cancer Ther. 2021 02; 20(2):450. PMID: 33547247.
      Citations:    Fields:    
    3. Su W, Han HH, Wang Y, Zhang B, Zhou B, Cheng Y, Rumandla A, Gurrapu S, Chakraborty G, Su J, Yang G, Liang X, Wang G, Rosen N, Scher HI, Ouerfelli O, Giancotti FG. The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression. Cancer Cell. 2019 08 12; 36(2):139-155.e10. PMID: 31327655.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    4. Laudato S, Aparicio A, Giancotti FG. Clonal Evolution and Epithelial Plasticity in the Emergence of AR-Independent Prostate Carcinoma. Trends Cancer. 2019 07; 5(7):440-455. PMID: 31311658.
      Citations: 6     Fields:    Translation:HumansCells
    5. Jain N, Hartert K, Tadros S, Fiskus W, Havranek O, Ma MCJ, Bouska A, Heavican T, Kumar D, Deng Q, Moore D, Pak C, Liu CL, Gentles AJ, Hartmann E, Kridel R, Smedby KE, Juliusson G, Rosenquist R, Gascoyne RD, Rosenwald A, Giancotti F, Neelapu SS, Westin J, Vose JM, Lunning MA, Greiner T, Rodig S, Iqbal J, Alizadeh AA, Davis RE, Bhalla K, Green MR. Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma. Sci Transl Med. 2019 06 19; 11(497). PMID: 31217338.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    6. Okada T, Sinha S, Esposito I, Schiavon G, López-Lago MA, Su W, Pratilas CA, Abele C, Hernandez JM, Ohara M, Okada M, Viale A, Heguy A, Socci ND, Sapino A, Seshan VE, Long S, Inghirami G, Rosen N, Giancotti FG. Author Correction: The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling. Nat Cell Biol. 2019 04; 21(4):534. PMID: 30842593.
      Citations: 4     Fields:    
    7. Cooper J, Giancotti FG. Integrin Signaling in Cancer: Mechanotransduction, Stemness, Epithelial Plasticity, and Therapeutic Resistance. Cancer Cell. 2019 03 18; 35(3):347-367. PMID: 30889378.
      Citations: 95     Fields:    Translation:HumansCells
    8. Er EE, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, Griscom B, Rosenblum M, Boire A, Brogi E, Giancotti FG, Schachner M, Malladi S, Massagué J. Author Correction: Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol. 2019 Mar; 21(3):408. PMID: 30542103.
      Citations: 1     Fields:    
    9. Er EE, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, Griscom B, Rosenblum M, Boire A, Brogi E, Giancotti FG, Schachner M, Malladi S, Massagué J. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol. 2018 08; 20(8):966-978. PMID: 30038252.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    10. Cooper J, Xu Q, Zhou L, Pavlovic M, Ojeda V, Moulick K, de Stanchina E, Poirier JT, Zauderer M, Rudin CM, Karajannis MA, Hanemann CO, Giancotti FG. Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis. Mol Cancer Ther. 2017 08; 16(8):1693-1704. PMID: 28468780.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    11. Cooper J, Giancotti FG. Cancer: a new role for non-canonical Hippo signaling. Cell Res. 2017 04; 27(4):459-460. PMID: 28244491.
      Citations: 1     Fields:    Translation:HumansCells
    12. Chen YB, Xu J, Skanderup AJ, Dong Y, Brannon AR, Wang L, Won HH, Wang PI, Nanjangud GJ, Jungbluth AA, Li W, Ojeda V, Hakimi AA, Voss MH, Schultz N, Motzer RJ, Russo P, Cheng EH, Giancotti FG, Lee W, Berger MF, Tickoo SK, Reuter VE, Hsieh JJ. Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets. Nat Commun. 2016 10 07; 7:13131. PMID: 27713405.
      Citations: 35     Fields:    Translation:HumansCells
    13. Gao H, Chakraborty G, Zhang Z, Akalay I, Gadiya M, Gao Y, Sinha S, Hu J, Jiang C, Akram M, Brogi E, Leitinger B, Giancotti FG. Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling. Cell. 2016 Jun 30; 166(1):47-62. PMID: 27368100.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    14. Garcia-Rendueles ME, Ricarte-Filho JC, Untch BR, Landa I, Knauf JA, Voza F, Smith VE, Ganly I, Taylor BS, Persaud Y, Oler G, Fang Y, Jhanwar SC, Viale A, Heguy A, Huberman KH, Giancotti F, Ghossein R, Fagin JA. NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition. Cancer Discov. 2015 Nov; 5(11):1178-93. PMID: 26359368.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    15. Giancotti FG, Haynes CM, Machesky LM, Olson MF, Overholtzer M. Alan Hall 1952-2015. Nat Cell Biol. 2015 Jul; 17(7):839-40. PMID: 26005836.
      Citations: 1     Fields:    
    16. Okada T, Sinha S, Esposito I, Schiavon G, López-Lago MA, Su W, Pratilas CA, Abele C, Hernandez JM, Ohara M, Okada M, Viale A, Heguy A, Socci ND, Sapino A, Seshan VE, Long S, Inghirami G, Rosen N, Giancotti FG. The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling. Nat Cell Biol. 2015 Jan; 17(1):81-94. PMID: 25531777.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    17. Gao H, Chakraborty G, Lee-Lim AP, Mavrakis KJ, Wendel HG, Giancotti FG. Forward genetic screens in mice uncover mediators and suppressors of metastatic reactivation. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):16532-7. PMID: 25378704.
      Citations: 16     Fields:    Translation:AnimalsCells
    18. Li W, Cooper J, Zhou L, Yang C, Erdjument-Bromage H, Zagzag D, Snuderl M, Ladanyi M, Hanemann CO, Zhou P, Karajannis MA, Giancotti FG. Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus. Cancer Cell. 2014 Jul 14; 26(1):48-60. PMID: 25026211.
      Citations: 92     Fields:    Translation:HumansAnimalsCells
    19. Cooper J, Giancotti FG. Molecular insights into NF2/Merlin tumor suppressor function. FEBS Lett. 2014 Aug 19; 588(16):2743-52. PMID: 24726726.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    20. Giancotti FG. Deregulation of cell signaling in cancer. FEBS Lett. 2014 Aug 19; 588(16):2558-70. PMID: 24561200.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    21. Karajannis MA, Legault G, Hagiwara M, Giancotti FG, Filatov A, Derman A, Hochman T, Goldberg JD, Vega E, Wisoff JH, Golfinos JG, Merkelson A, Roland JT, Allen JC. Phase II study of everolimus in children and adults with neurofibromatosis type 2 and progressive vestibular schwannomas. Neuro Oncol. 2014 Jan; 16(2):292-7. PMID: 24311643.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    22. Giancotti FG. Mechanisms governing metastatic dormancy and reactivation. Cell. 2013 Nov 07; 155(4):750-64. PMID: 24209616.
      Citations: 188     Fields:    Translation:HumansAnimalsCells
    23. Yoshioka T, Otero J, Chen Y, Kim YM, Koutcher JA, Satagopan J, Reuter V, Carver B, de Stanchina E, Enomoto K, Greenberg NM, Scardino PT, Scher HI, Sawyers CL, Giancotti FG. ß4 Integrin signaling induces expansion of prostate tumor progenitors. J Clin Invest. 2013 Feb; 123(2):682-99. PMID: 23348745.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    24. Gao H, Chakraborty G, Lee-Lim AP, Mo Q, Decker M, Vonica A, Shen R, Brogi E, Brivanlou AH, Giancotti FG. The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites. Cell. 2012 Aug 17; 150(4):764-79. PMID: 22901808.
      Citations: 164     Fields:    Translation:HumansAnimalsCells
    25. Ladanyi M, Zauderer MG, Krug LM, Ito T, McMillan R, Bott M, Giancotti F. New strategies in pleural mesothelioma: BAP1 and NF2 as novel targets for therapeutic development and risk assessment. Clin Cancer Res. 2012 Sep 01; 18(17):4485-90. PMID: 22825583.
      Citations: 26     Fields:    Translation:Humans
    26. Li W, Cooper J, Karajannis MA, Giancotti FG. Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus. EMBO Rep. 2012 Mar; 13(3):204-15. PMID: 22482125.
      Citations: 59     Translation:HumansAnimalsCells
    27. Kalamarides M, Acosta MT, Babovic-Vuksanovic D, Carpen O, Cichowski K, Evans DG, Giancotti F, Hanemann CO, Ingram D, Lloyd AC, Mayes DA, Messiaen L, Morrison H, North K, Packer R, Pan D, Stemmer-Rachamimov A, Upadhyaya M, Viskochil D, Wallace MR, Hunter-Schaedle K, Ratner N. Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting. Acta Neuropathol. 2012 Mar; 123(3):369-80. PMID: 22083253.
      Citations: 8     Fields:    Translation:Humans
    28. Baranwal S, Wang Y, Rathinam R, Lee J, Jin L, McGoey R, Pylayeva Y, Giancotti F, Blobe GC, Alahari SK. Molecular characterization of the tumor-suppressive function of nischarin in breast cancer. J Natl Cancer Inst. 2011 Oct 19; 103(20):1513-28. PMID: 21917605.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    29. Cooper J, Li W, You L, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG. Merlin/NF2 functions upstream of the nuclear E3 ubiquitin ligase CRL4DCAF1 to suppress oncogenic gene expression. Sci Signal. 2011 Aug 23; 4(188):pt6. PMID: 21878678.
      Citations: 16     Fields:    Translation:AnimalsCells
    30. Fan J, Cai B, Zeng M, Hao Y, Giancotti FG, Fu BM. Integrin ß4 signaling promotes mammary tumor cell adhesion to brain microvascular endothelium by inducing ErbB2-mediated secretion of VEGF. Ann Biomed Eng. 2011 Aug; 39(8):2223-2241. PMID: 21556948.
      Citations: 21     Fields:    Translation:AnimalsCells
    31. Li W, Giancotti FG. Merlin's tumor suppression linked to inhibition of the E3 ubiquitin ligase CRL4 (DCAF1). Cell Cycle. 2010 Nov 15; 9(22):4433-6. PMID: 21084862.
      Citations: 8     Translation:AnimalsCells
    32. Rossi F, Yozgat Y, de Stanchina E, Veach D, Clarkson B, Manova K, Giancotti FG, Antonescu CR, Besmer P. Imatinib upregulates compensatory integrin signaling in a mouse model of gastrointestinal stromal tumor and is more effective when combined with dasatinib. Mol Cancer Res. 2010 Sep; 8(9):1271-83. PMID: 20736294.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    33. Li W, You L, Cooper J, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG. Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus. Cell. 2010 Feb 19; 140(4):477-90. PMID: 20178741.
      Citations: 156     Fields:    Translation:HumansAnimalsCells
    34. Ammoun S, Cunliffe CH, Allen JC, Chiriboga L, Giancotti FG, Zagzag D, Hanemann CO, Karajannis MA. ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma. Neuro Oncol. 2010 Aug; 12(8):834-43. PMID: 20511180.
      Citations: 37     Fields:    Translation:HumansCells
    35. López-Lago MA, Okada T, Murillo MM, Socci N, Giancotti FG. Loss of the tumor suppressor gene NF2, encoding merlin, constitutively activates integrin-dependent mTORC1 signaling. Mol Cell Biol. 2009 Aug; 29(15):4235-49. PMID: 19451229.
      Citations: 71     Fields:    Translation:HumansCells
    36. Pylayeva Y, Gillen KM, Gerald W, Beggs HE, Reichardt LF, Giancotti FG. Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling. J Clin Invest. 2009 Feb; 119(2):252-66. PMID: 19147981.
      Citations: 132     Fields:    Translation:HumansAnimalsCells
    37. Giancotti FG. Targeting integrin beta4 for cancer and anti-angiogenic therapy. Trends Pharmacol Sci. 2007 Oct; 28(10):506-11. PMID: 17822782.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    38. Okada T, You L, Giancotti FG. Shedding light on Merlin's wizardry. Trends Cell Biol. 2007 May; 17(5):222-9. PMID: 17442573.
      Citations: 48     Fields:    Translation:HumansAnimals
    39. Pylayeva Y, Guo W, Giancotti FG. Analysis of integrin signaling in genetically engineered mouse models of mammary tumor progression. Methods Enzymol. 2007; 426:439-61. PMID: 17697895.
      Citations: 3     Fields:    Translation:AnimalsCells
    40. Guo W, Pylayeva Y, Pepe A, Yoshioka T, Muller WJ, Inghirami G, Giancotti FG. Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis. Cell. 2006 Aug 11; 126(3):489-502. PMID: 16901783.
      Citations: 211     Fields:    Translation:AnimalsCells
    41. Pylayeva Y, Giancotti FG. Development requires activation but not phosphorylation of beta1 integrins. Genes Dev. 2006 May 01; 20(9):1057-60. PMID: 16651652.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    42. Okada T, Lopez-Lago M, Giancotti FG. Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane. J Cell Biol. 2005 Oct 24; 171(2):361-71. PMID: 16247032.
      Citations: 77     Fields:    Translation:HumansCells
    43. Nikolopoulos SN, Blaikie P, Yoshioka T, Guo W, Puri C, Tacchetti C, Giancotti FG. Targeted deletion of the integrin beta4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-kappaB, causing defects in epidermal growth and migration. Mol Cell Biol. 2005 Jul; 25(14):6090-102. PMID: 15988021.
      Citations: 49     Fields:    Translation:AnimalsCells
    44. Vidal A, Zacharoulis S, Guo W, Shaffer D, Giancotti F, Bramley AH, de la Hoz C, Jensen KK, Kato D, MacDonald DD, Knowles J, Yeh N, Frohman LA, Rafii S, Lyden D, Koff A. p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow. Proc Natl Acad Sci U S A. 2005 May 10; 102(19):6890-5. PMID: 15867156.
      Citations: 9     Fields:    Translation:AnimalsCells
    45. Nikolopoulos SN, Giancotti FG. Netrin-integrin signaling in epithelial morphogenesis, axon guidance and vascular patterning. Cell Cycle. 2005 Mar; 4(3):e131-5. PMID: 15725728.
      Citations: 44     Translation:HumansAnimalsCells
    46. Nikolopoulos SN, Blaikie P, Yoshioka T, Guo W, Giancotti FG. Integrin beta4 signaling promotes tumor angiogenesis. Cancer Cell. 2004 Nov; 6(5):471-83. PMID: 15542431.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    47. Guo W, Giancotti FG. Integrin signalling during tumour progression. Nat Rev Mol Cell Biol. 2004 Oct; 5(10):816-26. PMID: 15459662.
      Citations: 499     Fields:    Translation:Cells
    48. Gagnoux-Palacios L, Dans M, van't Hof W, Mariotti A, Pepe A, Meneguzzi G, Resh MD, Giancotti FG. Compartmentalization of integrin alpha6beta4 signaling in lipid rafts. J Cell Biol. 2003 Sep 29; 162(7):1189-96. PMID: 14517202.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    49. Giancotti FG. A structural view of integrin activation and signaling. Dev Cell. 2003 Feb; 4(2):149-51. PMID: 12586058.
      Citations: 22     Fields:    Translation:HumansCells
    50. Giancotti FG, Tarone G. Positional control of cell fate through joint integrin/receptor protein kinase signaling. Annu Rev Cell Dev Biol. 2003; 19:173-206. PMID: 14570568.
      Citations: 137     Fields:    Translation:HumansAnimalsCells
    51. Klein S, de Fougerolles AR, Blaikie P, Khan L, Pepe A, Green CD, Koteliansky V, Giancotti FG. Alpha 5 beta 1 integrin activates an NF-kappa B-dependent program of gene expression important for angiogenesis and inflammation. Mol Cell Biol. 2002 Aug; 22(16):5912-22. PMID: 12138201.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    52. Hirsch E, Barberis L, Brancaccio M, Azzolino O, Xu D, Kyriakis JM, Silengo L, Giancotti FG, Tarone G, Fässler R, Altruda F. Defective Rac-mediated proliferation and survival after targeted mutation of the beta1 integrin cytodomain. J Cell Biol. 2002 Apr 29; 157(3):481-92. PMID: 11980921.
      Citations: 26     Fields:    Translation:AnimalsCells
    53. Mariotti A, Kedeshian PA, Dans M, Curatola AM, Gagnoux-Palacios L, Giancotti FG. EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion. J Cell Biol. 2001 Oct 29; 155(3):447-58. PMID: 11684709.
      Citations: 106     Fields:    Translation:HumansAnimalsCells
    54. Mettouchi A, Klein S, Guo W, Lopez-Lago M, Lemichez E, Westwick JK, Giancotti FG. Integrin-specific activation of Rac controls progression through the G(1) phase of the cell cycle. Mol Cell. 2001 Jul; 8(1):115-27. PMID: 11511365.
      Citations: 80     Fields:    Translation:HumansCells
    55. Dans M, Giancotti FG. CD104. J Biol Regul Homeost Agents. 2001 Apr-Jun; 15(2):193-6. PMID: 11501983.
      Citations:    Fields:    Translation:HumansAnimalsCells
    56. Dans M, Gagnoux-Palacios L, Blaikie P, Klein S, Mariotti A, Giancotti FG. Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes. J Biol Chem. 2001 Jan 12; 276(2):1494-502. PMID: 11044453.
      Citations: 59     Fields:    Translation:HumansCells
    57. Barberis L, Wary KK, Fiucci G, Liu F, Hirsch E, Brancaccio M, Altruda F, Tarone G, Giancotti FG. Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK. J Biol Chem. 2000 Nov 24; 275(47):36532-40. PMID: 10976102.
      Citations: 32     Fields:    Translation:AnimalsCells
    58. Giancotti FG, Ruoslahti E. Integrin signaling. Science. 1999 Aug 13; 285(5430):1028-32. PMID: 10446041.
      Citations: 1078     Fields:    Translation:HumansAnimalsCells
    59. Oktay M, Wary KK, Dans M, Birge RB, Giancotti FG. Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle. J Cell Biol. 1999 Jun 28; 145(7):1461-9. PMID: 10385525.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    60. Wary KK, Dans M, Mariotti A, Giancotti FG. Biochemical analysis of integrin-mediated Shc signaling. Methods Mol Biol. 1999; 129:35-49. PMID: 10494556.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    61. Oktay MH, Mariotti A, Giancotti FG. Assays for kinase activity. Methods Mol Biol. 1999; 129:51-61. PMID: 10494557.
      Citations:    Fields:    Translation:HumansAnimalsCells
    62. Wary KK, Mariotti A, Zurzolo C, Giancotti FG. A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell. 1998 Sep 04; 94(5):625-34. PMID: 9741627.
      Citations: 172     Fields:    Translation:AnimalsCells
    63. Murgia C, Blaikie P, Kim N, Dans M, Petrie HT, Giancotti FG. Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain. EMBO J. 1998 Jul 15; 17(14):3940-51. PMID: 9670011.
      Citations: 35     Fields:    Translation:AnimalsCells
    64. Giancotti FG. Integrin signaling: specificity and control of cell survival and cell cycle progression. Curr Opin Cell Biol. 1997 Oct; 9(5):691-700. PMID: 9330873.
      Citations: 93     Fields:    Translation:AnimalsCells
    65. Klein S, Bikfalvi A, Birkenmeier TM, Giancotti FG, Rifkin DB. Integrin regulation by endogenous expression of 18-kDa fibroblast growth factor-2. J Biol Chem. 1996 Sep 13; 271(37):22583-90. PMID: 8798427.
      Citations: 10     Fields:    Translation:AnimalsCells
    66. Klein S, Giancotti FG, Presta M, Albelda SM, Buck CA, Rifkin DB. Basic fibroblast growth factor modulates integrin expression in microvascular endothelial cells. Mol Biol Cell. 1993 Oct; 4(10):973-82. PMID: 8298194.
      Citations: 37     Fields:    Translation:AnimalsCells
    67. Effects of integrin signaling on mammary tumor cells adhesion to microvascular endothelium in vivo. 175-176.
    68. Expression of fibronectin receptor activity on immature hemopoietic cells. Cell Biology International Reports. 10:173.
    69. Erratum. EMBO Journal. 19:5585.
    70. Effects of VEGF on adhesion of mammary carcinoma cells to brain microvascular endothelium.
    71. RSV transformed fibroblasts and monocytes share peculiar adhesion sites. Cell Biology International Reports. 10:161.
    72. Erratum. Molecular and Cellular Biology. 25:7926.
    73. Integrin expression in the developing mouse retina. Investigative Ophthalmology and Visual Science. 37.
    74. NF2 loss promotes oncogenic RAS-induced thyroid cancers via YAP-dependent transactivation of RAS proteins and sensitizes them to MEK inhibition. Cancer Discovery. 5:1178-1193.
    75. Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets. Nature Communications. 7.
    76. Merlin. EMBO Reports.
    77. Do cell cycle inhibitors promote angiogenesis by altering the bone marrow microenvironment?. Cancer Biology and Therapy. 4.
    78. Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling. Cell. 166:47-62.
    79. EGF-R signaling through Fyn kinase disrupts the function of integrin α6β4 at hemidesmosomes. Journal of Cell Biology. 155:447-457.
    80. The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling. Nature Cell Biology. 17:81-94.
    81. The adapter protein. Kidney International. 56:1189.
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