TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1102 BATES
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kay A, Mendez-Reyes J, Devezin T, Bakaya M, Steffy T, Dlamini S, Msekandiana A, Ness T, Bacha J, Amuge P, Matshaba M, Chodota M, Nyasulu P, Thahane L, Mwita L, Kekitiinwa A, DiNardo A, Lukhele B, Kirchner HL, Mandalakas A. Optimal Timing of Antiretroviral Therapy Initiation in Children and Adolescents With Human Immunodeficiency Virus-Associated Pulmonary Tuberculosis. Clin Infect Dis. 2023 01 06; 76(1):10-17. PMID: 36097966; PMCID: PMC9825818.
    2. Vasiliu A, Abelman R, Kherabi Y, Iswari Saktiawati AM, Kay A. Landscape of TB Infection and Prevention among People Living with HIV. Pathogens. 2022 Dec 16; 11(12). PMID: 36558886.
    3. Ness TE, Meiwes L, Kay A, Mejia R, Lange C, Farhat M, Mandalakas A, DiNardo A. Optimizing DNA Extraction from Pediatric Stool for Diagnosis of Tuberculosis and Use in Next-Generation Sequencing Applications. Microbiol Spectr. 2023 02 14; 11(1):e0226922. PMID: 36475757; PMCID: PMC9927083.
    4. Kherabi Y, Tunesi S, Kay A, Guglielmetti L. Preventive Therapy for Contacts of Drug-Resistant Tuberculosis. Pathogens. 2022 Oct 15; 11(10). PMID: 36297246; PMCID: PMC9609446.
    5. Sibandze DB, Kay A, Dreyer V, Sikhondze W, Dlamini Q, DiNardo A, Mtetwa G, Lukhele B, Vambe D, Lange C, Dlamini MG, Ness T, Mejia R, Kalsdorf B, Heyckendorf J, Kuhns M, Maurer FP, Dlamini S, Maphalala G, Niemann S, Mandalakas A. Correction: Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing. Genome Med. 2022 Sep 20; 14(1):107. PMID: 36127736; PMCID: PMC9487157.
    6. Kay AW, Ness T, Verkuijl SE, Viney K, Brands A, Masini T, Gonz?lez Fern?ndez L, Eisenhut M, Detjen AK, Mandalakas AM, Steingart KR, Takwoingi Y. Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children. Cochrane Database Syst Rev. 2022 09 06; 9:CD013359. PMID: 36065889; PMCID: PMC9446385.
    7. Martinez L, Cords O, Liu Q, Acuna-Villaorduna C, Bonnet M, Fox GJ, Carvalho ACC, Chan PC, Croda J, Hill PC, Lopez-Varela E, Donkor S, Fielding K, Graham SM, Espinal MA, Kampmann B, Reingold A, Huerga H, Villalba JA, Grandjean L, Sotgiu G, Egere U, Singh S, Zhu L, Lienhardt C, Denholm JT, Seddon JA, Whalen CC, Garc?a-Basteiro AL, Triasih R, Chen C, Singh J, Huang LM, Sharma S, Hannoun D, Del Corral H, Mandalakas AM, Malone LL, Ling DL, Kritski A, Stein CM, Vashishtha R, Boulahbal F, Fang CT, Boom WH, Netto EM, Lemos AC, Hesseling AC, Kay A, Jones-L?pez EC, Horsburgh CR, Lange C, Andrews JR. Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis. Lancet Glob Health. 2022 09; 10(9):e1307-e1316. PMID: 35961354.
    8. Huang Z, LaCourse SM, Kay AW, Stern J, Escudero JN, Youngquist BM, Zheng W, Vambe D, Dlamini M, Mtetwa G, Cranmer LM, Njuguna I, Wamalwa DC, Maleche-Obimbo E, Catanzaro DG, Lyon CJ, John-Stewart G, DiNardo A, Mandalakas AM, Ning B, Hu TY. CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study. Lancet Microbe. 2022 07; 3(7):e482-e492. PMID: 35659882; PMCID: PMC9300929.
      Citations:    Translation:HumansCells
    9. Sibandze DB, Kay A, Dreyer V, Sikhondze W, Dlamini Q, DiNardo A, Mtetwa G, Lukhele B, Vambe D, Lange C, Glenn Dlamini M, Ness T, Mejia R, Kuhns M, Dlamini S, Maphalala G, Niemann S, Mandalakas A, Kalsdorf B, Heyckendorf J, Maurer FP. Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing. Genome Med. 2022 05 19; 14(1):52. PMID: 35585607; PMCID: PMC9118838.
      Citations: 1     Fields:    Translation:HumansCells
    10. Kay AW, Sandoval M, Mtetwa G, Mkhabela M, Ndlovu B, Devezin T, Sikhondze W, Vambe D, Sibanda J, Dube GS, Stevens RH, Lukhele B, Mandalakas AM. Vikela Ekhaya: A Novel, Community-based, Tuberculosis Contact Management Program in a High Burden Setting. Clin Infect Dis. 2022 05 03; 74(9):1631-1638. PMID: 34302733; PMCID: PMC9070808.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    11. Kay AW, Rabie H, Maleche-Obimbo E, Sekadde MP, Cotton MF, Mandalakas AM. HIV-Associated Tuberculosis in Children and Adolescents: Evolving Epidemiology, Screening, Prevention and Management Strategies. Pathogens. 2021 Dec 29; 11(1). PMID: 35055981; PMCID: PMC8780758.
      Citations: 1     
    12. Thivalapill N, Simelane T, Mthethwa N, Dlamini S, Lukhele B, Okello V, Kirchner HL, Mandalakas AM, Kay AW. Transition to Dolutegravir Is Associated With an Increase in the Rate of Body Mass Index Change in a Cohort of Virally Suppressed Adolescents. Clin Infect Dis. 2021 08 02; 73(3):e580-e586. PMID: 33119739; PMCID: PMC8326552.
      Citations: 3     Fields:    Translation:Humans
    13. Ronge L, Sloot R, Du Preez K, Kay AW, Kirchner HL, Grewal HMS, Mandalakas AM, Hesseling AC. The Magnitude of Interferon Gamma Release Assay Responses in Children With Household Tuberculosis Contact Is Associated With Tuberculosis Exposure and Disease Status. Pediatr Infect Dis J. 2021 08 01; 40(8):763-770. PMID: 34050092; PMCID: PMC8277676.
      Citations:    Fields:    Translation:HumansCells
    14. Vonasek B, Ness T, Takwoingi Y, Kay AW, van Wyk SS, Ouellette L, Marais BJ, Steingart KR, Mandalakas AM. Screening tests for active pulmonary tuberculosis in children. Cochrane Database Syst Rev. 2021 06 28; 6:CD013693. PMID: 34180536; PMCID: PMC8237391.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    15. Jasumback CL, Dlamini Q, Kahari J, Maphalala G, Dlamini MG, Dube GS, DiNardo A, Kirchner HL, Mandalakas A, Kay AW. Laboratory comparison of stool processing methods for Xpert? Ultra. Public Health Action. 2021 Jun 21; 11(2):55-57. PMID: 34159062; PMCID: PMC8202631.
      Citations: 2     
    16. Mandalakas AM, Hesseling AC, Kay A, Du Preez K, Martinez L, Ronge L, DiNardo A, Lange C, Kirchner HL. Tuberculosis prevention in children: a prospective community-based study in South Africa. Eur Respir J. 2021 04; 57(4). PMID: 33122339; PMCID: PMC8060782.
      Citations: 3     Fields:    Translation:Humans
    17. Ness TE, Streatfield AE, Simelane T, Korsa A, Dlamini S, Guffey D, Lukhele B, Kay AW. Evaluating antibiotic use and developing a tool to optimize prescribing in a family-centered HIV clinic in Eswatini. PLoS One. 2021; 16(1):e0244247. PMID: 33411762; PMCID: PMC7790297.
      Citations:    Fields:    Translation:Humans
    18. Vonasek B, Kay A, Devezin T, Bacha JM, Kazembe P, Dhillon D, Dlamini S, Haq H, Thahane L, Simon K, Matshaba M, Sanders J, Minde M, Wanless S, Nyasulu P, Mandalakas A. Tuberculosis symptom screening for children and adolescents living with HIV in six high HIV/TB burden countries in Africa. AIDS. 2021 01 01; 35(1):73-79. PMID: 33048868; PMCID: PMC7752241.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    19. Kay AW, Thivalapill N, Skinner D, Dube GS, Dlamini N, Mzileni B, Fuentes P, Ustero P, Adams LV, Mandalakas AM. Predictors of suboptimal adherence to isoniazid preventive therapy among adolescents and children living with HIV. PLoS One. 2020; 15(12):e0243713. PMID: 33332462; PMCID: PMC7746166.
      Citations: 4     Fields:    Translation:Humans
    20. Thivalapill N, Jasumback CL, Perry SH, Dlamini L, Matsenjwa M, Masangane ZT, Mavimbela M, Mthethwa N, Kirchner HL, Mphaya J, Lukhele B, Mandalakas A, Kay AW. Predicting Sexually Transmitted Infections Among HIV+ Adolescents and Young Adults: A Novel Risk Score to Augment Syndromic Management in Eswatini. J Acquir Immune Defic Syndr. 2020 12 15; 85(5):543-552. PMID: 32947446.
      Citations:    Fields:    Translation:HumansPHPublic Health
    21. Mandalakas AM, Kay AW, Bacha JM, Devezin T, Golin R, Simon KR, Dhillon D, Dlamini S, DiNardo A, Matshaba M, Sanders J, Thahane L, Amuge PM, Ahmed S, Sekadde MP, Fida NG, Lukhele B, Chidah N, Damba D, Mhango J, Chodota M, Matsoso M, Kayabu A, Wanless RS, Schutze GE. Tuberculosis among Children and Adolescents at HIV Treatment Centers in Sub-Saharan Africa. Emerg Infect Dis. 2020 12; 26(12). PMID: 33219815; PMCID: PMC7706926.
      Citations: 4     Fields:    Translation:Humans
    22. Kay AW, Ness TE, Martinez L, Mandalakas AM. It Ain't Over Till It's Over: The Triple Threat of COVID-19, TB, and HIV. Am J Trop Med Hyg. 2020 10; 103(4):1348-1349. PMID: 32876009; PMCID: PMC7543805.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    23. Vambe D, Furin J, Howard AA, Dlamini T, Dlamini N, Shabangu A, Hassen F, Masuku S, Maha O, Wawa C, Mafukidze A, Altaye K, Sikhondze W, Gwitima T, Simelane T, Kerschberger B, Kay AW, Keus K. Bedaquiline and delamanid result in low rates of unfavourable outcomes among TB patients in Eswatini. Int J Tuberc Lung Dis. 2020 10 01; 24(10):1095-1102. PMID: 33126945.
      Citations: 2     Fields:    Translation:Humans
    24. Sandoval M, Swamy P, Kay AW, Alonso PU, Dube GS, Hlophe-Dlamini H, Mandalakas AM. Distinct Risk Factors for Clinical and Bacteriologically Confirmed Tuberculosis among Child Household Contacts in a High-Burden Setting. Am J Trop Med Hyg. 2020 12; 103(6):2506-2509. PMID: 32996456; PMCID: PMC7695104.
      Citations:    Fields:    Translation:HumansPHPublic Health
    25. Kay AW, Takwoingi Y, Eisenhut M, Detjen AK, Steingart KR, Mandalakas AM, Gonz?lez Fern?ndez L. Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children. Cochrane Database Syst Rev. 2020 08 27; 8:CD013359. PMID: 32853411; PMCID: PMC8078611.
      Citations: 22     Fields:    Translation:HumansCells
    26. DiNardo AR, Rajapakshe K, Nishiguchi T, Grimm SL, Mtetwa G, Dlamini Q, Kahari J, Mahapatra S, Kay A, Maphalala G, Mace EM, Makedonas G, Cirillo JD, Netea MG, van Crevel R, Coarfa C, Mandalakas AM. DNA hypermethylation during tuberculosis dampens host immune responsiveness. J Clin Invest. 2020 06 01; 130(6):3113-3123. PMID: 32125282; PMCID: PMC7260034.
      Citations: 15     Fields:    Translation:HumansCells
    27. Jasumback CL, Perry SH, Ness TE, Matsenjwa M, Masangane ZT, Mavimbela M, Mthethwa N, Dlamini L, Mphaya J, Kirchner HL, Mandalakas A, Kay AW. Point-of-Care Testing to Guide Treatment and Estimate Risk Factors for Sexually Transmitted Infections in Adolescents and Young People With Human Immunodeficiency Virus in Eswatini. Open Forum Infect Dis. 2020 Mar; 7(3):ofaa052. PMID: 32190707; PMCID: PMC7071112.
      Citations: 3     
    28. Le Gars M, Seiler C, Kay AW, Bayless NL, Starosvetsky E, Moore L, Shen-Orr SS, Aziz N, Khatri P, Dekker CL, Swan GE, Davis MM, Holmes S, Blish CA. Pregnancy-Induced Alterations in NK Cell Phenotype and Function. Front Immunol. 2019; 10:2469. PMID: 31708922; PMCID: PMC6820503.
      Citations: 22     Fields:    Translation:HumansCells
    29. Lange C, Aarnoutse RE, Alffenaar JWC, Bothamley G, Brinkmann F, Costa J, Chesov D, van Crevel R, Dedicoat M, Dominguez J, Duarte R, Grobbel HP, Guglielmetti L, Heyckendorf J, Kay AW, Kirakosyan O, Kirk O, Koczulla RA, Kudriashov GG, Kuksa L, van Leth F, Magis-Escurra C, Mandalakas AM, Molina-Moya B, Peloquin CA, Reimann M, Rumetshofer R, Schaaf HS, Tiberi S, Valda J, Yablonskii PK, Dheda K, G?nther G, Sch?n T. Management of patients with multidrug-resistant tuberculosis. Int J Tuberc Lung Dis. 2019 06 01; 23(6):645-662. PMID: 31315696.
      Citations: 18     Fields:    Translation:HumansCells
    30. Martinez L, Lo NC, Cords O, Hill PC, Khan P, Hatherill M, Mandalakas A, Kay A, Horsburgh CR, Zar HJ, Andrews JR, Croda J. Paediatric tuberculosis transmission outside the household: challenging historical paradigms to inform future public health strategies. Lancet Respir Med. 2019 06; 7(6):544-552. PMID: 31078497; PMCID: PMC7323920.
      Citations: 23     Fields:    Translation:HumansCellsPHPublic Health
    31. Kay AW, DiNardo AR, Dlamini Q, Kahari J, Mndzebele T, Mtetwa G, Ustero P, Maphalala G, Mandalakas AM. Evaluation of the QuantiFERON-Tuberculosis Gold Plus Assay in Children with Tuberculosis Disease or Following Household Exposure to Tuberculosis. Am J Trop Med Hyg. 2019 03; 100(3):540-543. PMID: 30675853; PMCID: PMC6402910.
      Citations: 8     Fields:    Translation:HumansCells
    32. Kay A, Garcia-Prats AJ, Mandalakas AM. HIV-associated pediatric tuberculosis: prevention, diagnosis and treatment. Curr Opin HIV AIDS. 2018 11; 13(6):501-506. PMID: 30286040.
      Citations: 2     Fields:    Translation:HumansCells
    33. DiNardo AR, Nishiguchi T, Mace EM, Rajapakshe K, Mtetwa G, Kay A, Maphalala G, Secor WE, Mejia R, Orange JS, Coarfa C, Bhalla KN, Graviss EA, Mandalakas AM, Makedonas G. Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-Specific Immune Changes. J Immunol. 2018 07 01; 201(1):124-133. PMID: 29752313; PMCID: PMC6008220.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    34. Kay AW, Islam SM, Wendorf K, Westenhouse J, Barry PM. Interferon-? Release Assay Performance for Tuberculosis in Childhood. Pediatrics. 2018 06; 141(6). PMID: 29728429.
      Citations: 15     Fields:    Translation:HumansCells
    35. DiNardo AR, Kay AW, Maphalala G, Harris NM, Fung C, Mtetwa G, Ustero P, Dlamini S, Ha N, Graviss EA, Mejia R, Mandalakas AM. Diagnostic and Treatment Monitoring Potential of A Stool-Based Quantitative Polymerase Chain Reaction Assay for Pulmonary Tuberculosis. Am J Trop Med Hyg. 2018 08; 99(2):310-316. PMID: 29692304; PMCID: PMC6090360.
      Citations: 10     Fields:    Translation:HumansCells
    36. Brunetti M, Rajasekharan S, Ustero P, Ngo K, Sikhondze W, Mzileni B, Mandalakas A, Kay AW. Leveraging tuberculosis case relative locations to enhance case detection and linkage to care in Swaziland. Glob Health Res Policy. 2018; 3:3. PMID: 29445773; PMCID: PMC5798177.
      Citations: 1     Fields:    
    37. Kay A, Barry PM, Annambhotla P, Greene C, Cilnis M, Chin-Hong P, Arger N, McNitt L, Neidlinger N, Shah N, Basavaraju SV, Kuehnert M, Shaw T. Solid Organ Transplant-Transmitted Tuberculosis Linked to a Community Outbreak - California, 2015. MMWR Morb Mortal Wkly Rep. 2017 Aug 04; 66(30):801-805. PMID: 28771459; PMCID: PMC5720876.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    38. Ustero PA, Kay AW, Ngo K, Golin R, Tsabedze B, Mzileni B, Glickman J, Wisile Xaba M, Mavimbela G, Mandalakas AM. School and household tuberculosis contact investigations in Swaziland: Active TB case finding in a high HIV/TB burden setting. PLoS One. 2017; 12(6):e0178873. PMID: 28582435; PMCID: PMC5459449.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    39. Le Gars M, Kay AW, Bayless NL, Aziz N, Dekker CL, Swan GE, Davis MM, Blish CA. Increased Proinflammatory Responses of Monocytes and Plasmacytoid Dendritic Cells to Influenza A Virus Infection During Pregnancy. J Infect Dis. 2016 Dec 01; 214(11):1666-1671. PMID: 27655870; PMCID: PMC5144734.
      Citations: 23     Fields:    Translation:HumansCells
    40. Barry PM, Kay AW, Flood JM, Watt J. Getting to Zero: Tuberculosis Elimination in California. Curr Epidemiol Rep. 2016; 3:136-144. PMID: 27218013; PMCID: PMC4846683.
      Citations: 4     
    41. Kay AW, Strauss-Albee DM, Blish CA. Application of Mass Cytometry (CyTOF) for Functional and Phenotypic Analysis of Natural Killer Cells. Methods Mol Biol. 2016; 1441:13-26. PMID: 27177653; PMCID: PMC5304457.
      Citations: 28     Fields:    Translation:HumansCells
    42. Kay AW, Blish CA. Immunogenicity and Clinical Efficacy of Influenza Vaccination in Pregnancy. Front Immunol. 2015; 6:289. PMID: 26089824; PMCID: PMC4455389.
      Citations: 13     Fields:    
    43. Kay AW, Bayless NL, Fukuyama J, Aziz N, Dekker CL, Mackey S, Swan GE, Davis MM, Blish CA. Pregnancy Does Not Attenuate the Antibody or Plasmablast Response to Inactivated Influenza Vaccine. J Infect Dis. 2015 Sep 15; 212(6):861-70. PMID: 25740957; PMCID: PMC4548461.
      Citations: 21     Fields:    Translation:HumansCells
    44. Kay AW, Fukuyama J, Aziz N, Dekker CL, Mackey S, Swan GE, Davis MM, Holmes S, Blish CA. Enhanced natural killer-cell and T-cell responses to influenza A virus during pregnancy. Proc Natl Acad Sci U S A. 2014 Oct 07; 111(40):14506-11. PMID: 25246558; PMCID: PMC4210016.
      Citations: 44     Fields:    Translation:HumansCellsPHPublic Health
    45. Kay AW, Blish CA. Delayed BCG vaccination--time to take a shot. J Infect Dis. 2015 Feb 01; 211(3):335-7. PMID: 25108029.
      Citations: 2     Fields:    Translation:HumansCells
    46. Kay AW, Itoh M, Valdez J, Chen SF, Mathew R, Gans HA. Pleural Effusion and Fever in an Immunocompromised Patient. J Pediatric Infect Dis Soc. 2015 Mar; 4(1):e6-9. PMID: 26407371.
      Citations: 1     Fields:    Translation:HumansCells
    47. Li L, Kay AW, Hong DK. Seizure and meningoencephalitis in an adolescent. Clin Pediatr (Phila). 2013 Dec; 52(12):1181-3. PMID: 24137030.
      Citations:    Fields:    Translation:Humans
    48. Kay AW, McCarthy CA. Renal and miliary tuberculosis in an internationally adopted infant. Pediatr Infect Dis J. 2009 Aug; 28(8):751-3. PMID: 19633525.
      Citations: 3     Fields:    Translation:HumansCells
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