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VLAD SANDULACHE

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Otolaryngology-Head and Neck Surgery
Address6501 Fannin St
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology

    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Radiation Oncology
    DivisionRadiation Oncology


    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Li Y, Yadollahi P, Essien F, Putluri V, Chandra S, Kami Reddy KR, Kamal A, Putluri N, Abdurrahman LM, Ruiz-Echartea E, Ernste K, Trivedi A, Vazquez-Perez J, Hudson WH, Decker W, Patel R, Osman AA, Kheradmand F, Lai SY, Myers JN, Skinner HD, Coarfa C, Lee K, Jain A, Malovannaya A, Frederick MJ, Sandulache VC. Tobacco smoke exposure is a driver of altered oxidative stress response and immunity in head and neck cancer. bioRxiv. 2024 Oct 21. PMID: 39484602; PMCID: PMC11526855.
      Citations:    
    2. Frederick MJ, Perez-Bello D, Yadollahi P, Castro P, Frederick A, Frederick A, Osman RA, Essien F, Yebra I, Hamlin A, Ow TJ, Skinner HD, Sandulache VC. Reliable RNA-seq analysis from FFPE specimens as a means to accelerate cancer-related health disparities research. bioRxiv. 2024 Oct 11. PMID: 39416147; PMCID: PMC11482925.
      Citations:    
    3. MD Anderson Head and Neck Symptom Working Group, Humbert-Vidan L, Kamel S, Wentzel A, Kaffey Z, Abdelaal M, Spier KB, West NA, Marai GE, Canahuate G, Zhang X, Chen MM, Wahid KA, Rigert J, Hosseinian S, Schaefer AJ, Brock KK, Chambers M, Otun AO, Aponte-Wesson R, Patel V, Hope A, Phan J, Garden AS, Frank SJ, Morrison WH, Spiotto MT, Rosenthal D, Lee A, He R, Naser MA, Watson E, Hutcheson KA, Mohamed ASR, Sandulache VC, van Dijk LV, Moreno AC, Guerrero Urbano T, Lai SY, Fuller CD, Collaborators: . Mandibular dose-volume predicts time-to-osteoradionecrosis in an actuarial normal-tissue complication probability (NTCP) model: External validation of right-censored clinico-dosimetric and competing risk application across international multi-institutional observational cohorts and online graphical user interface clinical support tool assessment. medRxiv. 2024 Aug 20. PMID: 39228724; PMCID: PMC11370531.
      Citations:    
    4. Lai SY, Sandulache VC, Schellingerhout D, Fuller CD, Chen Y, Walker CM, Bankson JA. First-in-Human Hyperpolarized MRI for Tumor Metabolism in HNSCC. JAMA Otolaryngol Head Neck Surg. 2024 Jul 01; 150(7):628-630. PMID: 38780963; PMCID: PMC11349323.
      Citations:    Fields:    Translation:Humans
    5. Schuman AD, Bindal M, Amadio G, Turney AM, Hernandez DJ, Sandulache VC, Liou NE, Wang R, Huang AT. Safety of An Enhanced Recovery After Surgery Protocol After Head and Neck Free Tissue Transfer. Laryngoscope. 2024 Nov; 134(11):4527-4534. PMID: 38895890.
      Citations:    Fields:    Translation:Humans
    6. Multidisciplinary OPC ENE Group, Multidisciplinary Oropharyngeal Cancer Extra-Nodal Extension (OPC ENE) Assessment Working Group, Sahin O, Kamel S, Wahid KA, Dede C, Taku N, He R, Naser MA, Sharafi S, M?kitie A, Kann BH, Kaski K, Sahlsten J, Jaskari J, Amit M, Chronowski GM, Diaz EM, Garden AS, Goepfert RP, Guenette JP, Gunn GB, Hirvonen J, Hoebers F, Hutcheson KA, Guha-Thakurta N, Johnson J, Kaya D, Khanpara SD, Nyman K, Lai SY, Lango M, Learned KO, Lee A, Lewis CM, Maniakas A, Moreno AC, Myers JN, Phan J, Pytynia KB, Rosenthal DI, Sandulache VC, Schellingerhout D, Shah SJ, Sikora AG, Mohamed ASR, Chen MM, Fuller CD. International Multi-Specialty Expert Physician Preoperative Identification of Extranodal Extension n Oropharyngeal Cancer Patients using Computed Tomography: Prospective Blinded Human Inter-Observer Performance Evaluation. medRxiv. 2024 Jun 08. PMID: 36865096; PMCID: PMC9980252.
      Citations:    
    7. Duckett KA, Kassir MF, Nguyen SA, Brennan EA, Chera BS, Sterba KR, Halbert CH, Hill EG, McCay J, Puram SV, Jackson RS, Sandulache VC, Kahmke R, Osazuwa-Peters N, Ramadan S, Nussenbaum B, Alberg AJ, Graboyes EM. Factors Associated with Head and Neck Cancer Postoperative Radiotherapy Delays: A Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. 2024 Nov; 171(5):1265-1282. PMID: 38842034; PMCID: PMC11499046.
      Citations: 1     Fields:    Translation:Humans
    8. Graboyes EM, Cagle JL, Ramadan S, Prasad K, Yan F, Pearce J, Mazul AL, Anoma JS, Hill EG, Chera BS, Puram SV, Jackson R, Sandulache VC, Tam S, Topf MC, Kahmke R, Osazuwa-Peters N, Nussenbaum B, Alberg AJ, Sterba KR, Halbert CH. Neighborhood-Level Disadvantage and Delayed Adjuvant Therapy in Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg. 2024 Jun 01; 150(6):472-482. PMID: 38662392; PMCID: PMC11046410.
      Citations: 1     Fields:    Translation:Humans
    9. Halpert MM, Burns BA, Rosario SR, Withers HG, Trivedi AJ, Hofferek CJ, Gephart BD, Wang H, Vazquez-Perez J, Amanya SB, Hyslop ST, Yang J, Kemnade JO, Sandulache VC, Konduri V, Decker WK. Multifactoral immune modulation potentiates durable remission in multiple models of aggressive malignancy. FASEB J. 2024 May 31; 38(10):e23644. PMID: 38738472; PMCID: PMC11155525.
      Citations:    Fields:    Translation:HumansAnimalsCells
    10. Duckett KA, Lee BJ, Chera BS, Puram SV, Sandulache VC, Kahmke R, Nguyen SA, Nussenbaum B, Alberg AJ, Halbert CH, Sterba KR, Graboyes EM. Author Reply to Letter by Topkan et al Regarding Delays in Starting Postoperative Radiotherapy. Otolaryngol Head Neck Surg. 2024 Jul; 171(1):315-316. PMID: 38655738; PMCID: PMC11211055.
      Citations:    Fields:    Translation:Humans
    11. Kansara S, Oral E, Sarkar I, Sandulache V, Mualla R, Walvekar RR, Ryan W, Ha P. Rate of occult metastasis in lip squamous cell carcinoma: A systematic review and meta-analysis. Head Neck. 2024 Mar 18. PMID: 38497534.
      Citations:    Fields:    
    12. Sandulache VC, Kirby RP, Lai SY. Moving from conventional to adaptive risk stratification for oropharyngeal cancer. Front Oncol. 2024; 14:1287010. PMID: 38549938; PMCID: PMC10972883.
      Citations:    
    13. Yassin-Kassab A, Chatterjee S, Khan N, Wang N, Sandulache VC, Huang EH, Burns TF, Duvvuri U. p90RSK pathway inhibition synergizes with cisplatin in TMEM16A overexpressing head and neck cancer. BMC Cancer. 2024 Feb 19; 24(1):233. PMID: 38373988; PMCID: PMC10875868.
      Citations:    Fields:    Translation:HumansCells
    14. Pifer PM, Yang L, Kumar M, Xie T, Frederick M, Hefner A, Beadle B, Molkentine D, Molkentine J, Dhawan A, Abdelhakiem M, Osman AA, Leibowitz BJ, Myers JN, Pickering CR, Sandulache VC, Heymach J, Skinner HD. FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner. Clin Cancer Res. 2024 01 05; 30(1):187-197. PMID: 37819945; PMCID: PMC10767302.
      Citations: 3     Fields:    
    15. Graboyes EM, Chappell M, Duckett KA, Sterba K, Hughes Halbert C, Hill EG, Chera B, McCay J, Puram SV, Ramadan S, Sandulache VC, Kahmke R, Nussenbaum B, Alberg AJ, Paskett ED, Calhoun E. Patient Navigation for Timely, Guideline-Adherent Adjuvant Therapy for Head and Neck Cancer: A National Landscape Analysis. J Natl Compr Canc Netw. 2023 12; 21(12):1251-1259.e5. PMID: 38081134; PMCID: PMC10846494.
      Citations: 1     Fields:    Translation:Humans
    16. Gallagher KK, Hernandez DJ, Sturgis EM, Wang RY, Sandulache VC, Huang AT. Outcomes of Head and Neck Microvascular Free Tissue Transfer for Advanced Cutaneous Squamous Cell Carcinoma: A Comparison of Solid Organ Transplant Recipients to Nontransplant Patients. J Oral Maxillofac Surg. 2024 03; 82(3):347-355. PMID: 38103578.
      Citations:    Fields:    Translation:Humans
    17. Castro P, Corredor G, Koyuncu C, Nordstrom LA, Tiji M, Leavitt T, Lewis JS, Madabhushi A, Frederick MJ, Sandulache VC. Recurrent Oropharyngeal Squamous Cell Carcinomas Maintain Anti-tumor Immunity and Multinucleation Levels Following Completion of Radiation. Head Neck Pathol. 2023 Dec; 17(4):952-960. PMID: 37995073; PMCID: PMC10739687.
      Citations:    Fields:    Translation:HumansCells
    18. Duckett KA, Kassir MF, Nguyen SA, Brennan EA, Chera BS, Sterba KR, Hughes Halbert C, Hill EG, McCay J, Puram SV, Sandulache VC, Kahmke R, Ramadan S, Nussenbaum B, Alberg AJ, Graboyes EM. Delays Starting Postoperative Radiotherapy Among Head and Neck Cancer Patients: A Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. 2024 Feb; 170(2):320-334. PMID: 37731255; PMCID: PMC10840985.
      Citations:    Fields:    Translation:Humans
    19. Hernandez DJ, Xu W, Lim Y, Dong JL, Huang AT, Chiu L, Awad S, Joseph L, Sandulache VC. Operationalizing a Free Flap Program for Head and Neck Reconstruction at a Veterans Affairs Hospital. OTO Open. 2023 Jul-Sep; 7(3):e80. PMID: 37693829; PMCID: PMC10487330.
      Citations:    
    20. Fujita J, Krishnan B, Green LK, Sandulache VC, Lai S. Secretory Carcinoma with ETV6-NTRK3 Gene Fusion and Lymph Node Metastasis in Maxillary Gingiva: A Case Report with Pathological and Molecular Correlative Studies. Ann Clin Lab Sci. 2023 Sep; 53(5):800-805. PMID: 37945013.
      Citations:    Fields:    Translation:Humans
    21. Castro P, Corredor G, Koyuncu C, Nordstrom LA, Tiji M, Leavitt T, Lewis JS, Madabhushi A, Frederick MJ, Sandulache VC. Recurrent oropharyngeal squamous cell carcinomas maintain anti-tumor immunity and multinucleation levels following completion of radiation. Res Sq. 2023 Aug 21. PMID: 37674722; PMCID: PMC10479446.
      Citations:    
    22. Kemnade JO, Florez M, Sabichi A, Zhang J, Jhaveri P, Chen G, Chen A, Miller-Chism C, Shaun B, Hilsenbeck SG, Hernandez DJ, Skinner HD, Sandulache VC. Phase I / II trial of metformin as a chemo-radiosensitizer in a head and neck cancer patient population. Oral Oncol. 2023 10; 145:106536. PMID: 37562095.
      Citations:    Fields:    Translation:Humans
    23. Flanagan KC, Earls J, Schillebeeckx I, Hiken J, Wellinghoff RL, LaFranzo NA, Bradley ZS, Babbitt J, Westra WH, Hsu R, Nadauld L, Mcleod H, Firth SD, Sharp B, Fuller J, Vavinskaya V, Sutton L, Deichaite I, Bailey SD, Sandulache VC, Rendo MJ, Macdonald OK, Welaya K, Wade JL, Pippas AW, Slim J, Bank B, Saccaro SJ, Sui X, Akhtar A, Balaraman S, Kossman SE, Sonnier SA, Shenkenberg TD, Alexander WL, Price KA, Bane CL, Ley J, Messina DN, Glasscock JI, Cohen EEW, Adkins DR, Duncavage EJ. Multidimensional biomarker predicts disease control in response to immunotherapy in recurrent or metastatic head and neck squamous-cell carcinoma. J Cancer Res Clin Oncol. 2023 Nov; 149(15):14125-14136. PMID: 37552307; PMCID: PMC10590294.
      Citations: 1     Fields:    
    24. Soliman O, Wilde DC, Kemnade JO, Sabichi AL, Chen G, Chen A, Little SN, Huang AT, Hernandez DJ, Sandulache VC. Deployment of cisplatin in Veterans with oropharyngeal cancer: toxicity and impact on oncologic outcomes. Laryngoscope Investig Otolaryngol. 2023 Aug; 8(4):895-902. PMID: 37621289; PMCID: PMC10446265.
      Citations:    
    25. Coviello CM, Sheehan C, Hernandez DJ, Liou NE, Sandulache VC, Haskins AD, Sturgis EM, Huang AT. Outcome Comparison of Functional Laryngectomy for the Dysfunctional Larynx to Salvage Laryngectomy. Laryngoscope. 2024 01; 134(1):222-227. PMID: 37345670.
      Citations:    Fields:    Translation:Humans
    26. Koyuncu CF, Frederick MJ, Thompson LDR, Corredor G, Khalighi S, Zhang Z, Song B, Lu C, Nag R, Sankar Viswanathan V, Gilkey M, Yang K, Koyfman SA, Chute DJ, Castro P, Lewis JS, Madabhushi A, Sandulache VC. Machine learning driven index of tumor multinucleation correlates with survival and suppressed anti-tumor immunity in head and neck squamous cell carcinoma patients. Oral Oncol. 2023 Aug; 143:106459. PMID: 37307602; PMCID: PMC10330801.
      Citations: 2     Fields:    Translation:Humans
    27. Chidambaram S, Chang SH, Sandulache VC, Mazul AL, Zevallos JP. Human Papillomavirus Vaccination Prevalence and Disproportionate Cancer Burden Among US Veterans. JAMA Oncol. 2023 05 01; 9(5):712-714. PMID: 36862390; PMCID: PMC9982736.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    28. Sandulache VC, Hernandez DJ. Response to letter to the editor: Early detection of mandible osteoradionecrosis risk in a high comorbidity veteran population. Am J Otolaryngol. 2023 Jul-Aug; 44(4):103892. PMID: 37068321.
      Citations:    Fields:    Translation:Humans
    29. Yu W, Chen Y, Putluri N, Osman A, Coarfa C, Putluri V, Kamal AHM, Asmussen JK, Katsonis P, Myers JN, Lai SY, Lu W, Stephan CC, Powell RT, Johnson FM, Skinner HD, Kazi J, Ahmed KM, Hu L, Threet A, Meyer MD, Bankson JA, Wang T, Davis J, Parker KR, Harris MA, Baek ML, Echeverria GV, Qi X, Wang J, Frederick AI, Walsh AJ, Lichtarge O, Frederick MJ, Sandulache VC. Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state. Br J Cancer. 2023 06; 128(11):2013-2024. PMID: 37012319; PMCID: PMC10205814.
      Citations: 1     Fields:    Translation:HumansCells
    30. Osman AA, Arslan E, Bartels M, Michikawa C, Lindemann A, Tomczak K, Yu W, Sandulache V, Ma W, Shen L, Wang J, Singh AK, Frederick MJ, Spencer ND, Kovacs J, Heffernan T, Symmans WF, Rai K, Myers JN. Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma. Clin Cancer Res. 2023 04 03; 29(7):1344-1359. PMID: 36689560; PMCID: PMC10068451.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    31. Liu Y, Kramer JR, Sandulache VC, Yu R, Li G, Chen L, Yusuf ZI, Shi Y, Pyarajan S, Tsavachidis S, Jiao L, Mierzwa ML, Chiao E, Mowery YM, Shuman A, Shete S, Sikora AG, White DL. Immunogenetic Determinants of Susceptibility to Head and Neck Cancer in the Million Veteran Program Cohort. Cancer Res. 2023 02 03; 83(3):386-397. PMID: 36378845; PMCID: PMC9896026.
      Citations:    Fields:    Translation:HumansCells
    32. Wilde DC, Kansara S, Banner L, Morlen R, Hernandez D, Huang AT, Mai W, Fuller CD, Lai S, Sandulache VC. Early detection of mandible osteoradionecrosis risk in a high comorbidity veteran population. Am J Otolaryngol. 2023 Mar-Apr; 44(2):103781. PMID: 36640532; PMCID: PMC11349716.
      Citations:    Fields:    Translation:Humans
    33. Goldberg M, Manzi A, Birdi A, Laporte B, Conway P, Cantin S, Mishra V, Singh A, Pearson AT, Goldberg ER, Goldberger S, Flaum B, Hasina R, London NR, Gallia GL, Bettegowda C, Young S, Sandulache V, Melville J, Shun J, O'Neill SE, Aydin E, Zhavoronkov A, Vidal A, Soto A, Alonso MJ, Rosenberg AJ, Lingen MW, D'Cruz A, Agrawal N, Izumchenko E. Author Correction: A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer. Nat Commun. 2022 Dec 21; 13(1):7865. PMID: 36543765; PMCID: PMC9772340.
      Citations:    Fields:    
    34. Dhawan A, Pifer PM, Sandulache VC, Skinner HD. Metabolic targeting, immunotherapy and radiation in locally advanced non-small cell lung cancer: Where do we go from here? Front Oncol. 2022; 12:1016217. PMID: 36591457; PMCID: PMC9794617.
      Citations:    
    35. Koyuncu CF, Nag R, Lu C, Corredor G, Viswanathan VS, Sandulache VC, Fu P, Yang K, Pan Q, Zhang Z, Xu J, Chute DJ, Thorstad WL, Faraji F, Bishop JA, Mehrad M, Castro PD, Sikora AG, Thompson LDR, Chernock RD, Lang Kuhs KA, Wasman JK, Luo JR, Adelstein DJ, Koyfman SA, Lewis JS, Madabhushi A. Image analysis reveals differences in tumor multinucleations in Black and White patients with human papillomavirus-associated oropharyngeal squamous cell carcinoma. Cancer. 2022 11 01; 128(21):3831-3842. PMID: 36066461; PMCID: PMC9782693.
      Citations:    
    36. Goldberg M, Manzi A, Birdi A, Laporte B, Conway P, Cantin S, Mishra V, Singh A, Pearson AT, Goldberg ER, Goldberger S, Flaum B, Hasina R, London NR, Gallia GL, Bettegowda C, Young S, Sandulache V, Melville J, Shum J, O'Neill SE, Aydin E, Zhavoronkov A, Vidal A, Soto A, Alonso MJ, Rosenberg AJ, Lingen MW, D'Cruz A, Agrawal N, Izumchenko E. A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer. Nat Commun. 2022 08 17; 13(1):4829. PMID: 35977936; PMCID: PMC9385702.
      Citations:    
    37. Ahmed KM, Veeramachaneni R, Deng D, Putluri N, Putluri V, Cardenas MF, Wheeler DA, Decker WK, Frederick AI, Kazi S, Sikora AG, Sandulache VC, Frederick MJ. Glutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response. J Immunother Cancer. 2022 08; 10(8). PMID: 36002187; PMCID: PMC9413193.
      Citations:    
    38. Sapienza LG, Thomas JJ, Mai W, Hanania AN, Hunjan S, Sandulache VC, Chen AC. Three-dimensional (3D) anatomic location, extension, and timing of severe osteoradionecrosis of the mandible. Rep Pract Oncol Radiother. 2022; 27(3):519-526. PMID: 36186684; PMCID: PMC9518768.
      Citations:    
    39. Florez MA, Kemnade JO, Chen N, Du W, Sabichi AL, Wang DY, Huang Q, Miller-Chism CN, Jotwani A, Chen AC, Hernandez D, Sandulache VC. Persistent ethnicity-associated disparity in anti-tumor effectiveness of immune checkpoint inhibitors despite equal access. Cancer Res Commun. 2022 07 26; 2022. PMID: 35966167; PMCID: PMC9367161.
      Citations:    
    40. Mazul AL, Hartman CM, Mowery YM, Kramer JR, White DL, Royse KE, Raychaudhury S, Sandulache VC, Ahmed ST, Zevallos JP, Richardson PA, Sikora AG, Chiao EY. Risk and incidence of head and neck cancers in veterans living with HIV and matched HIV-negative veterans. Cancer. 2022 09 15; 128(18):3310-3318. PMID: 35867552; PMCID: PMC10650941.
      Citations:    Fields:    
    41. Wang R, Horwich P, Sandulache VC, Hernandez DJ, Hornig J, Graboyes EM, Liou NE, Skoner J, Haskins AD, Ranasinghe V, Day TA, Sturgis EM, Huang AT. Safety of microvascular free tissue transfer reconstruction of the head and neck in the setting of chronic pharmacologic immunosuppression. Head Neck. 2022 07; 44(7):1520-1527. PMID: 35437907.
      Citations:    Fields:    Translation:Humans
    42. Toro P, Koyuncu C, Lu C, Buzzy C, Bera K, Fu P, Mehrad M, Ely KA, Mokhtari M, Yang K, Chute D, Adelstein DJ, Thompson LDR, Bishop JA, Faraji F, Thorstad W, Castro P, Sandulache V, Koyfman SA, Lewis JS, Madabhushi A, Corredor G. An Imaging Biomarker of Tumor-Infiltrating Lymphocytes to Risk-Stratify Patients With HPV-Associated Oropharyngeal Cancer. J Natl Cancer Inst. 2022 04 11; 114(4):609-617. PMID: 34850048; PMCID: PMC9002277.
      Citations:    Fields:    Translation:HumansCells
    43. Wahle BM, Zolkind P, Ramirez RJ, Skidmore ZL, Anderson SR, Mazul A, Hayes DN, Sandulache VC, Thorstad WL, Adkins D, Griffith OL, Griffith M, Zevallos JP. Integrative genomic analysis reveals low T-cell infiltration as the primary feature of tobacco use in HPV-positive oropharyngeal cancer. iScience. 2022 May 20; 25(5):104216. PMID: 35494251; PMCID: PMC9044176.
      Citations:    
    44. Molkentine DP, Molkentine JM, Bridges KA, Valdecanas DR, Dhawan A, Bahri R, Hefner AJ, Kumar M, Yang L, Abdelhakiem M, Pifer PM, Sandulache V, Sheth A, Beadle BM, Thames HD, Mason KA, Pickering CR, Meyn RE, Skinner HD. p16 Represses DNA Damage Repair via a Novel Ubiquitin-Dependent Signaling Cascade. Cancer Res. 2022 03 01; 82(5):916-928. PMID: 34965932; PMCID: PMC9136619.
      Citations: 1     Fields:    Translation:HumansCells
    45. Wilde DC, Castro PD, Bera K, Lai S, Madabhushi A, Corredor G, Koyuncu C, Lewis JS, Lu C, Frederick MJ, Frederick AM, Haugen AE, Zevallos JP, Sturgis EM, Shi J, Huang AT, Hernandez DJ, Skinner HD, Kemnade JO, Yu W, Sikora AG, Sandulache VC. Oropharyngeal cancer outcomes correlate with p16 status, multinucleation and immune infiltration. Mod Pathol. 2022 08; 35(8):1045-1054. PMID: 35184149; PMCID: PMC10391519.
      Citations:    Fields:    Translation:HumansCells
    46. Goyal N, Day A, Epstein J, Goodman J, Graboyes E, Jalisi S, Kiess AP, Ku JA, Miller MC, Panwar A, Patel VA, Sacco A, Sandulache V, Williams AM, Deschler D, Farwell DG, Nathan CA, Fakhry C, Agrawal N. Head and neck cancer survivorship consensus statement from the American Head and Neck Society. Laryngoscope Investig Otolaryngol. 2022 Feb; 7(1):70-92. PMID: 35155786; PMCID: PMC8823162.
      Citations:    
    47. Henderson YC, Mohamed ASR, Maniakas A, Chen Y, Powell RT, Peng S, Cardenas M, Williams MD, Bell D, Zafereo ME, Wang RJ, Scherer SE, Wheeler DA, Cabanillas ME, Hofmann MC, Johnson FM, Stephan CC, Sandulache V, Lai SY. A High-throughput Approach to Identify Effective Systemic Agents for the Treatment of Anaplastic Thyroid Carcinoma. J Clin Endocrinol Metab. 2021 09 27; 106(10):2962-2978. PMID: 34120183; PMCID: PMC8475220.
      Citations:    Fields:    Translation:HumansAnimalsCells
    48. Hernandez DJ, Alam B, Kemnade JO, Huang AT, Chen AC, Sandulache VC. Consistent multimodality approach to oral cavity and high-risk oropharyngeal cancer in veterans. Am J Otolaryngol. 2021 Nov-Dec; 42(6):103166. PMID: 34333218; PMCID: PMC10317518.
      Citations:    Fields:    Translation:Humans
    49. Hebert KA, Jaramillo S, Yu W, Wang M, Veeramachaneni R, Sandulache VC, Sikora AG, Bonnen MD, Annapragada AV, Corry D, Kheradmand F, Pandita RK, Ludwig MS, Pandita TK, Huang S, Coarfa C, Grimm SL, Perera D, Miles G, Ghebre YT. Esomeprazole enhances the effect of ionizing radiation to improve tumor control. Oncotarget. 2021 Jul 06; 12(14):1339-1353. PMID: 34262645; PMCID: PMC8274720.
      Citations:    Fields:    
    50. Veeramachaneni R, Yu W, Newton JM, Kemnade JO, Skinner HD, Sikora AG, Sandulache VC. Metformin generates profound alterations in systemic and tumor immunity with associated antitumor effects. J Immunother Cancer. 2021 07; 9(7). PMID: 34230113; PMCID: PMC8261884.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    51. Koyuncu CF, Lu C, Bera K, Zhang Z, Xu J, Toro P, Corredor G, Chute D, Fu P, Thorstad WL, Faraji F, Bishop JA, Mehrad M, Castro PD, Sikora AG, Thompson LD, Chernock RD, Lang Kuhs KA, Luo J, Sandulache V, Adelstein DJ, Koyfman S, Lewis JS, Madabhushi A. Computerized tumor multinucleation index (MuNI) is prognostic in p16+ oropharyngeal carcinoma. J Clin Invest. 2021 04 15; 131(8). PMID: 33651718; PMCID: PMC8075166.
      Citations: 3     Fields:    Translation:Humans
    52. Chen Y, Maniakas A, Tan L, Cui M, Le X, Niedzielski JS, Michel KA, Harlan CJ, Lu W, Henderson YC, Mohamed ASR, Lorenzi PL, Putluri N, Bankson JA, Sandulache VC, Lai SY. Development of a rational strategy for integration of lactate dehydrogenase A suppression into therapeutic algorithms for head and neck cancer. Br J Cancer. 2021 05; 124(10):1670-1679. PMID: 33742144; PMCID: PMC8110762.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    53. Warren EAK, Anil J, Castro PD, Kemnade J, Suzuki M, Hegde M, Hicks J, Yu W, Sandulache V, Sikora AG. Human epidermal growth factor receptor 2 expression in head and neck squamous cell carcinoma: Variation within and across primary tumor sites, and implications for antigen-specific immunotherapy. Head Neck. 2021 07; 43(7):1983-1994. PMID: 33660372; PMCID: PMC10320663.
      Citations: 1     Fields:    Translation:Humans
    54. Shi J, Ayeni T, Gallagher KK, Patel AJ, Jalali A, Hernandez DJ, Haskins AD, Sandulache VC, Sturgis EM, Huang AT. Reconstructive Outcomes of Multilayered Closure of Large Skull Base Dural Defects Following Open Anterior Craniofacial Resection. J Neurol Surg B Skull Base. 2022 Aug; 83(4):359-366. PMID: 35903650; PMCID: PMC9324318.
      Citations:    
    55. Jurica JM, Rubio F, Hernandez DJ, Sandulache VC. Institutional financial toxicity of failure to adhere to treatment guidelines for head and neck squamous cell carcinoma. Head Neck. 2021 03; 43(3):816-824. PMID: 33166016.
      Citations:    Fields:    Translation:Humans
    56. Mazul AL, Hartman C, Kramer J, White DL, Royse K, Raychaudhury S, Sandulache V, Ahmed ST, Richardson P, Sikora AG, Chiao E. Incidence and survival for oropharynx and non-oropharynx head and neck cancers among veterans living with HIV. Cancer Med. 2020 12; 9(24):9326-9335. PMID: 33094910; PMCID: PMC7774719.
      Citations: 3     Fields:    Translation:HumansCells
    57. Wan P, Ongkasuwan J, Martinez J, Sandulache V, Deng D, Jiang J, Sikora A, Altman KW. Biomarkers for Malignant Potential in Vocal Fold Leukoplakia: A State of the Art Review. Otolaryngol Head Neck Surg. 2021 04; 164(4):751-758. PMID: 32988279.
      Citations: 2     Fields:    Translation:Humans
    58. Elhalawani H, Mohamed ASR, Elgohari B, Lin TA, Sikora AG, Lai SY, Abusaif A, Phan J, Morrison WH, Gunn GB, Rosenthal DI, Garden AS, Fuller CD, Sandulache VC. Tobacco exposure as a major modifier of oncologic outcomes in human papillomavirus (HPV) associated oropharyngeal squamous cell carcinoma. BMC Cancer. 2020 Sep 23; 20(1):912. PMID: 32967643; PMCID: PMC7513300.
      Citations: 6     Fields:    Translation:HumansCells
    59. Pham D, Deter CJ, Reinard MC, Gibson GA, Kiselyov K, Yu W, Sandulache VC, St Croix CM, Koide K. Using Ligand-Accelerated Catalysis to Repurpose Fluorogenic Reactions for Platinum or Copper. ACS Cent Sci. 2020 Oct 28; 6(10):1772-1788. PMID: 33145414; PMCID: PMC7596870.
      Citations: 1     
    60. Zevallos JP, Kramer JR, Sandulache VC, Massa ST, Hartman CM, Mazul AL, Wahle BM, Gerndt SP, Sturgis EM, Chiao EY. National trends in oropharyngeal cancer incidence and survival within the Veterans Affairs Health Care System. Head Neck. 2021 01; 43(1):108-115. PMID: 32918302; PMCID: PMC8060873.
      Citations: 1     Fields:    Translation:Humans
    61. Chen DW, Ellis MA, Horwich P, Sandulache VC, Liou NE, Hernandez DJ, Sturgis EM, Graboyes EM, Hornig JD, Day TA, Huang AT. Free Flap Inset Techniques in Salvage Laryngopharyngectomy Repair: Impact on Fistula Formation and Function. Laryngoscope. 2021 03; 131(3):E875-E881. PMID: 32833308.
      Citations: 2     Fields:    Translation:Humans
    62. Joint Head and Neck Radiation Therapy-MRI Development Cooperative, Mohamed ASR, He R, Ding Y, Wang J, Fahim J, Elgohari B, Elhalawani H, Kim AD, Ahmed H, Garcia JA, Johnson JM, Stafford RJ, Bankson JA, Chambers MS, Sandulache VC, Fuller CD, Lai SY. Quantitative Dynamic Contrast-Enhanced MRI Identifies Radiation-Induced Vascular Damage in Patients With Advanced Osteoradionecrosis: Results of a Prospective Study. Int J Radiat Oncol Biol Phys. 2020 12 01; 108(5):1319-1328. PMID: 32712257; PMCID: PMC7680450.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    63. Yu W, Chen Y, Putluri N, Coarfa C, Robertson MJ, Putluri V, Stossi F, Dubrulle J, Mancini MA, Pang JC, Nguyen T, Baluya D, Myers JN, Lai SY, Sandulache VC. Acquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism toward Neutralization of Oxidative Stress. Cancers (Basel). 2020 Jun 24; 12(6). PMID: 32599707; PMCID: PMC7352569.
      Citations: 8     
    64. Frederick M, Skinner HD, Kazi SA, Sikora AG, Sandulache VC. High expression of oxidative phosphorylation genes predicts improved survival in squamous cell carcinomas of the head and neck and lung. Sci Rep. 2020 04 14; 10(1):6380. PMID: 32286489; PMCID: PMC7156383.
      Citations: 3     Fields:    Translation:HumansCells
    65. Fullmer T, Wilde DC, Shi JW, Wagner T, Skinner H, Eicher SA, Sandulache VC, Hernandez DJ. Demographic and Tumor Characteristic Impact on Laryngeal Cancer Outcomes in a Minority Underserved Patient Population. Otolaryngol Head Neck Surg. 2020 Jun; 162(6):888-896. PMID: 32093532.
      Citations: 1     Fields:    Translation:Humans
    66. Porter CE, Rosewell Shaw A, Jung Y, Yip T, Castro PD, Sandulache VC, Sikora A, Gottschalk S, Ittman MM, Brenner MK, Suzuki M. Oncolytic Adenovirus Armed with BiTE, Cytokine, and Checkpoint Inhibitor Enables CAR T Cells to Control the Growth of Heterogeneous Tumors. Mol Ther. 2020 05 06; 28(5):1251-1262. PMID: 32145203; PMCID: PMC7210703.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    67. Kemnade JO, Elhalawani H, Castro P, Yu J, Lai S, Ittmann M, Mohamed ASR, Lai SY, Fuller CD, Sikora AG, Sandulache VC. CD8 infiltration is associated with disease control and tobacco exposure in intermediate-risk oropharyngeal cancer. Sci Rep. 2020 01 14; 10(1):243. PMID: 31937831; PMCID: PMC6959290.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    68. Lindquist NR, Appelbaum EN, Fullmer T, Sandulache VC, Sweeney AD. A Hurricane, Temporal Bone Paraganglioma, Cholesteatoma, Bezold's Abscess, and Necrotizing Fasciitis. Otol Neurotol. 2020 01; 41(1):e149-e151. PMID: 31789807.
      Citations: 1     Fields:    
    69. Sandulache VC, Lei YL, Heasley LE, Chang M, Amos CI, Sturgis EM, Graboyes E, Chiao EY, Rogus-Pulia N, Lewis J, Madabhushi A, Frederick MJ, Sabichi A, Ittmann M, Yarbrough WG, Chung CH, Ferrarotto R, Mai W, Skinner HD, Duvvuri U, Gerngross P, Sikora AG. Innovations in risk-stratification and treatment of Veterans with oropharynx cancer; roadmap of the 2019 Field Based Meeting. Oral Oncol. 2020 03; 102:104440. PMID: 31648864; PMCID: PMC7260859.
      Citations: 1     Fields:    Translation:HumansCells
    70. Sandulache VC, Wilde DC, Sturgis EM, Chiao EY, Sikora AG. A Hidden Epidemic of "Intermediate Risk" Oropharynx Cancer. Laryngoscope Investig Otolaryngol. 2019 Dec; 4(6):617-623. PMID: 31890879; PMCID: PMC6929570.
      Citations: 4     
    71. Chhabria K, Kansara S, Badr H, Stach C, Vernese M, Lerner A, Harms A, Hernandez DJ, Huang AT, Chen G, Parke RB, Charnitsky S, Sandulache VC. Gastrostomy Utilization by Oropharyngeal Cancer Patients Is Partially Driven by Swallowing Function. Laryngoscope. 2020 09; 130(9):2153-2159. PMID: 31566749.
      Citations: 1     Fields:    Translation:Humans
    72. Kansara S, Wang T, Koochakzadeh S, Liou NE, Graboyes EM, Skoner JM, Hornig JD, Sandulache VC, Day TA, Huang AT. Prognostic factors associated with achieving total oral diet following osteocutaneous microvascular free tissue transfer reconstruction of the oral cavity. Oral Oncol. 2019 11; 98:1-7. PMID: 31521884; PMCID: PMC6842118.
      Citations: 3     Fields:    Translation:Humans
    73. Fullmer TM, Shi J, Skinner HD, Hernandez DJ, Huang AT, Mai W, Parke RB, Donovan DT, Sandulache VC. Early glottic cancer in a veteran population: Impact of race on management and outcomes. Laryngoscope. 2020 07; 130(7):1733-1739. PMID: 31461171.
      Citations:    Fields:    Translation:Humans
    74. Pham N, Ludwig MS, Wang M, Ebrahimpour A, Bonnen MD, Diwan AH, Kim SJ, Bryan J, Newton JM, Sikora AG, Donovan DT, Sandulache V, Ghebre YT. Topical Esomeprazole Mitigates Radiation-Induced Dermal Inflammation and Fibrosis. Radiat Res. 2019 11; 192(5):473-482. PMID: 31415221; PMCID: PMC6876297.
      Citations: 6     Fields:    Translation:HumansAnimals
    75. Bakhshaie J, Bonnen M, Asper J, Sandulache V, Badr H. Emotional disclosure and cognitive processing in couples coping with head and neck cancer. J Behav Med. 2020 06; 43(3):411-425. PMID: 31414332; PMCID: PMC10064885.
      Citations: 2     Fields:    Translation:Humans
    76. Chen DW, Wang T, Shey-Sen Ni J, Sandulache VC, Graboyes EM, Worley M, Hornig JD, Skoner JM, Day TA, Huang AT. Prognostic factors associated with achieving total oral diet after glossectomy with microvascular free tissue transfer reconstruction. Oral Oncol. 2019 05; 92:59-66. PMID: 31010625; PMCID: PMC6510264.
      Citations: 2     Fields:    Translation:Humans
    77. Piyarathna DWB, Balasubramanian A, Arnold JM, Lloyd SM, Karanam B, Castro P, Ittmann MM, Putluri N, Navone N, Jones JA, Yu W, Sandulache VC, Sikora AG, Michailidis G, Sreekumar A. ERR1 and PGC1a associated mitochondrial alterations correlate with pan-cancer disparity in African Americans. J Clin Invest. 2019 03 28; 129(6):2351-2356. PMID: 30920960; PMCID: PMC6546480.
      Citations: 11     Fields:    Translation:HumansCells
    78. Harms A, Kansara S, Stach C, Richardson PA, Chen G, Lai S, Sikora AG, Parke R, Donovan D, Chiao E, Skinner H, Sandulache VC. Swallowing Function in Survivors of Oropharyngeal Cancer Is Associated With Advanced T Classification. Ann Otol Rhinol Laryngol. 2019 Aug; 128(8):696-703. PMID: 30913911.
      Citations:    Fields:    Translation:Humans
    79. Badr H, Herbert K, Chhabria K, Sandulache VC, Chiao EY, Wagner T. Self-management intervention for head and neck cancer couples: Results of a randomized pilot trial. Cancer. 2019 04 01; 125(7):1176-1184. PMID: 30521075; PMCID: PMC6420382.
      Citations: 9     Fields:    Translation:Humans
    80. Richardson PA, Kansara S, Chen GG, Sabichi A, Sikora AG, Parke RB, Donovan DT, Chiao E, Sandulache VC. Treatment Patterns in Veterans with Laryngeal and Oropharyngeal Cancer and Impact on Survival. Laryngoscope Investig Otolaryngol. 2018 Aug; 3(4):275-282. PMID: 30186958; PMCID: PMC6119785.
      Citations:    
    81. Patel RS, Mohr T, Hartman C, Stach C, Sikora AG, Zevallos JP, Sandulache VC. Tracheoesophageal Prosthesis Use Is Associated With Improved Overall Quality of Life in Veterans With Laryngeal Cancer. Ann Otol Rhinol Laryngol. 2018 Jul; 127(7):421-428. PMID: 29756480.
      Citations: 4     Fields:    Translation:Humans
    82. Tam S, Sandulache VC, Metwalli KA, Rock CD, Eraj SA, Sheu T, El-Naggar AK, Fuller CD, Weber RS, Lai SY. Incompletely treated malignancies of the major salivary gland: Toward evidence-based care. Head Neck. 2018 08; 40(8):1630-1638. PMID: 29734482.
      Citations: 1     Fields:    Translation:Humans
    83. Yu W, Chen Y, Dubrulle J, Stossi F, Putluri V, Sreekumar A, Putluri N, Baluya D, Lai SY, Sandulache VC. Cisplatin generates oxidative stress which is accompanied by rapid shifts in central carbon metabolism. Sci Rep. 2018 03 09; 8(1):4306. PMID: 29523854; PMCID: PMC5844883.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    84. Sandulache VC, Michikawa C, Kataria P, Gleber-Netto FO, Bell D, Trivedi S, Rao X, Wang J, Zhao M, Jasser S, Myers JN, Pickering CR. High-Risk TP53 Mutations Are Associated with Extranodal Extension in Oral Cavity Squamous Cell Carcinoma. Clin Cancer Res. 2018 04 01; 24(7):1727-1733. PMID: 29330202; PMCID: PMC5884733.
      Citations: 17     Fields:    Translation:Humans
    85. Hautmann MG, Pathak RR, Varier I, McLaren C, Gaag D, Evert M, Laban S, Sandulache V, Sikora AG, Krupar R, Hellerbrand C, Idel C, Perner S, Bosserhoff AK. Immunometabolic Determinants of Chemoradiotherapy Response and Survival in Head and Neck Squamous Cell Carcinoma. Am J Pathol. 2018 01; 188(1):72-83. PMID: 29107073.
      Citations: 11     Fields:    Translation:HumansCells
    86. Sandulache VC, Chen Y, Feng L, William WN, Skinner HD, Myers JN, Meyn RE, Li J, Mijiti A, Bankson JA, Fuller CD, Konopleva MY, Lai SY. Metabolic interrogation as a tool to optimize chemotherapeutic regimens. Oncotarget. 2017 Mar 14; 8(11):18154-18165. PMID: 28184025; PMCID: PMC5392315.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    87. Rao SN, Zafereo M, Dadu R, Busaidy NL, Hess K, Cote GJ, Williams MD, William WN, Sandulache V, Gross N, Gunn GB, Lu C, Ferrarotto R, Lai SY, Cabanillas ME. Patterns of Treatment Failure in Anaplastic Thyroid Carcinoma. Thyroid. 2017 05; 27(5):672-681. PMID: 28068873; PMCID: PMC5802249.
      Citations: 44     Fields:    Translation:Humans
    88. Pezzi TA, Mohamed ASR, Sheu T, Blanchard P, Sandulache VC, Lai SY, Cabanillas ME, Williams MD, Pezzi CM, Lu C, Garden AS, Morrison WH, Rosenthal DI, Fuller CD, Gunn GB. Radiation therapy dose is associated with improved survival for unresected anaplastic thyroid carcinoma: Outcomes from the National Cancer Data Base. Cancer. 2017 05 01; 123(9):1653-1661. PMID: 28026871; PMCID: PMC5906051.
      Citations: 22     Fields:    Translation:Humans
    89. Sandulache VC, Williams MD, Lai SY, Lu C, William WN, Busaidy NL, Cote GJ, Singh RR, Luthra R, Cabanillas ME. Real-Time Genomic Characterization Utilizing Circulating Cell-Free DNA in Patients with Anaplastic Thyroid Carcinoma. Thyroid. 2017 01; 27(1):81-87. PMID: 27785980; PMCID: PMC5704769.
      Citations: 28     Fields:    Translation:Humans
    90. Sandulache VC, Vandelaar LJ, Skinner HD, Cata J, Hutcheson K, Fuller CD, Phan J, Siddiqui Z, Lai SY, Weber RS, Zafereo ME. Salvage total laryngectomy after external-beam radiotherapy: A 20-year experience. Head Neck. 2016 04; 38 Suppl 1:E1962-8. PMID: 26879395; PMCID: PMC5300043.
      Citations: 9     Fields:    Translation:Humans
    91. Pezzi TA, Sandulache VC, Pezzi CM, Turkeltaub AE, Feng L, Cabanillas ME, Williams MD, Lai SY. Treatment and survival of patients with insular thyroid carcinoma: 508 cases from the National Cancer Data Base. Head Neck. 2016 06; 38(6):906-12. PMID: 26843481.
      Citations: 6     Fields:    Translation:Humans
    92. Messer JA, Mohamed AS, Hutcheson KA, Ding Y, Lewin JS, Wang J, Lai SY, Frank SJ, Garden AS, Sandulache V, Eichelberger H, French CC, Colen RR, Phan J, Kalpathy-Cramer J, Hazle JD, Rosenthal DI, Gunn GB, Fuller CD. Magnetic resonance imaging of swallowing-related structures in nasopharyngeal carcinoma patients receiving IMRT: Longitudinal dose-response characterization of quantitative signal kinetics. Radiother Oncol. 2016 Feb; 118(2):315-22. PMID: 26830697; PMCID: PMC4794348.
      Citations: 14     Fields:    Translation:HumansPHPublic Health
    93. Lai S, Wenaas AE, Sandulache VC, Hartman C, Chiao E, Kramer J, Zevallos JP. Prognostic Significance of p16 Cellular Localization in Oropharyngeal Squamous Cell Carcinoma. Ann Clin Lab Sci. 2016; 46(2):132-9. PMID: 27098618.
      Citations: 9     Fields:    Translation:Humans
    94. Bankson JA, Walker CM, Ramirez MS, Stefan W, Fuentes D, Merritt ME, Lee J, Sandulache VC, Chen Y, Phan L, Chou PC, Rao A, Yeung SC, Lee MH, Schellingerhout D, Conrad CA, Malloy C, Sherry AD, Lai SY, Hazle JD. Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors. Cancer Res. 2015 Nov 15; 75(22):4708-17. PMID: 26420214; PMCID: PMC4651725.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    95. Sandulache VC, Chen Y, Skinner HD, Lu T, Feng L, Court LE, Myers JN, Meyn RE, Fuller CD, Bankson JA, Lai SY. Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model. Mol Cancer Ther. 2015 Dec; 14(12):2901-8. PMID: 26376962; PMCID: PMC4762176.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    96. Lee J, Ramirez MS, Walker CM, Chen Y, Yi S, Sandulache VC, Lai SY, Bankson JA. High-throughput hyperpolarized (13)C metabolic investigations using a multi-channel acquisition system. J Magn Reson. 2015 Nov; 260:20-7. PMID: 26397217; PMCID: PMC4628838.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    97. Sandulache VC, Hamblin J, Lai S, Pezzi T, Skinner HD, Khan NA, Dioun SM, Hartman C, Kramer J, Chiao E, Zhou X, Zevallos JP. Oropharyngeal squamous cell carcinoma in the veteran population: Association with traditional carcinogen exposure and poor clinical outcomes. Head Neck. 2015 Sep; 37(9):1246-53. PMID: 24801106; PMCID: PMC4496314.
      Citations: 10     Fields:    Translation:Humans
    98. Fitzgerald AL, Osman AA, Xie TX, Patel A, Skinner H, Sandulache V, Myers JN. Reactive oxygen species and p21Waf1/Cip1 are both essential for p53-mediated senescence of head and neck cancer cells. Cell Death Dis. 2015 Mar 12; 6:e1678. PMID: 25766317; PMCID: PMC4385922.
      Citations:    
    99. Zevallos JP, Sandulache VC, Hamblin J, Skinner HD, Kramer J, Hartman CM, Horter KL, Lai S, Zhou X, Chiao EY. Impact of race on oropharyngeal squamous cell carcinoma presentation and outcomes among veterans. Head Neck. 2016 Jan; 38(1):44-50. PMID: 24992520.
      Citations: 8     Fields:    Translation:HumansCells
    100. Gelbard A, Francis DO, Sandulache VC, Simmons JC, Donovan DT, Ongkasuwan J. Causes and consequences of adult laryngotracheal stenosis. Laryngoscope. 2015 May; 125(5):1137-43. PMID: 25290987; PMCID: PMC4562418.
      Citations: 68     Fields:    Translation:Humans
    101. Zhou G, Wang J, Zhao M, Xie TX, Tanaka N, Sano D, Patel AA, Ward AM, Sandulache VC, Jasser SA, Skinner HD, Fitzgerald AL, Osman AA, Wei Y, Xia X, Songyang Z, Mills GB, Hung MC, Caulin C, Liang J, Myers JN. Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation. Mol Cell. 2014 Jun 19; 54(6):960-974. PMID: 24857548; PMCID: PMC4067806.
      Citations: 119     Fields:    Translation:HumansAnimalsCells
    102. Sandulache VC, Kupferman ME. Transoral laser surgery for laryngeal cancer. Rambam Maimonides Med J. 2014 Apr; 5(2):e0012. PMID: 24808950; PMCID: PMC4011477.
      Citations: 1     
    103. Sandulache VC, Hamblin JS, Skinner HD, Kubik MW, Myers JN, Zevallos JP. Association between metformin use and improved survival in patients with laryngeal squamous cell carcinoma. Head Neck. 2014 Jul; 36(7):1039-43. PMID: 23784886.
      Citations: 23     Fields:    Translation:Humans
    104. Sandulache VC, Chen Y, Lee J, Rubinstein A, Ramirez MS, Skinner HD, Walker CM, Williams MD, Tailor R, Court LE, Bankson JA, Lai SY. Evaluation of hyperpolarized [1-??C]-pyruvate by magnetic resonance to detect ionizing radiation effects in real time. PLoS One. 2014; 9(1):e87031. PMID: 24475215; PMCID: PMC3903593.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    105. Sandulache VC, Yang L, Skinner HD. Use of biguanides to improve response to chemotherapy. Methods Mol Biol. 2014; 1165:3-9. PMID: 24839014.
      Citations:    Fields:    Translation:Humans
    106. Woo SH, Sandulache VC, Yang L, Skinner HD. Evaluating response to metformin/cisplatin combination in cancer cells via metabolic measurement and clonogenic survival. Methods Mol Biol. 2014; 1165:11-8. PMID: 24839015.
      Citations: 3     Fields:    Translation:HumansCells
    107. Hamblin JS, Sandulache VC, Alapat PM, Takashima M. Management of obstructive sleep apnea in the indigent population: a deviation of standard of care? Otolaryngol Head Neck Surg. 2014 Mar; 150(3):346-7. PMID: 24316791.
      Citations:    Fields:    Translation:Humans
    108. Ramirez MS, Lee J, Walker CM, Sandulache VC, Hennel F, Lai SY, Bankson JA. Radial spectroscopic MRI of hyperpolarized [1-(13) C] pyruvate at 7 tesla. Magn Reson Med. 2014 Oct; 72(4):986-95. PMID: 24186845; PMCID: PMC4007384.
      Citations: 17     Fields:    Translation:Animals
    109. Ow TJ, Sandulache VC, Skinner HD, Myers JN. Integration of cancer genomics with treatment selection: from the genome to predictive biomarkers. Cancer. 2013 Nov 15; 119(22):3914-28. PMID: 24037788; PMCID: PMC3930628.
      Citations: 6     Fields:    Translation:Humans
    110. Sandulache VC, Kubik MW, Skinner HD, Malsky JA, Gelbard AH, Zevallos JP. Impact of race/ethnicity on laryngeal cancer in patients treated at a Veterans Affairs Medical Center. Laryngoscope. 2013 Sep; 123(9):2170-5. PMID: 23729204.
      Citations: 6     Fields:    Translation:Humans
    111. Hamilton JD, Ahmed S, Sandulache VC, Daram SP, Ow TJ, Skinner HD, Rao A, Ginsberg LE, Kumar AJ, Myers JN. Improving imaging diagnosis of persistent nodal metastases after definitive therapy for oropharyngeal carcinoma: specific signs for CT and best performance of combined criteria. AJNR Am J Neuroradiol. 2013 Aug; 34(8):1637-42. PMID: 23471023; PMCID: PMC3939678.
      Citations: 4     Fields:    Translation:Humans
    112. Skinner HD, Crane CH, Garrett CR, Eng C, Chang GJ, Skibber JM, Rodriguez-Bigas MA, Kelly P, Sandulache VC, Delclos ME, Krishnan S, Das P. Metformin use and improved response to therapy in rectal cancer. Cancer Med. 2013 Feb; 2(1):99-107. PMID: 24133632; PMCID: PMC3797563.
      Citations: 41     Fields:    Translation:Humans
    113. Tobey AB, Sandulache VC, Yang T, Barsic M, Lin Y, Dohar JE, Hebda PA, Cetin S. Cyclooxygenase-2 inhibition for the prevention of subglottic stenosis. Arch Otolaryngol Head Neck Surg. 2012 Oct; 138(10):962-8. PMID: 23069827; PMCID: PMC4126655.
      Citations:    Fields:    Translation:Animals
    114. Sandulache VC, Ow TJ, Daram SP, Hamilton J, Skinner H, Bell D, Rosenthal DI, Beadle BM, Ang KK, Kies MS, Johnson FM, El-Naggar AK, Myers JN. Residual nodal disease in patients with advanced-stage oropharyngeal squamous cell carcinoma treated with definitive radiation therapy and posttreatment neck dissection: Association with locoregional recurrence, distant metastasis, and decreased survival. Head Neck. 2013 Oct; 35(10):1454-60. PMID: 23018868.
      Citations: 2     Fields:    Translation:Humans
    115. Skinner HD, McCurdy MR, Echeverria AE, Lin SH, Welsh JW, O'Reilly MS, Hofstetter WL, Ajani JA, Komaki R, Cox JD, Sandulache VC, Myers JN, Guerrero TM. Metformin use and improved response to therapy in esophageal adenocarcinoma. Acta Oncol. 2013 Jun; 52(5):1002-9. PMID: 22950385.
      Citations: 41     Fields:    Translation:Humans
    116. Sandulache VC, Skinner HD, Wang Y, Chen Y, Dodge CT, Ow TJ, Bankson JA, Myers JN, Lai SY. Glycolytic inhibition alters anaplastic thyroid carcinoma tumor metabolism and improves response to conventional chemotherapy and radiation. Mol Cancer Ther. 2012 Jun; 11(6):1373-80. PMID: 22572813; PMCID: PMC3856684.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    117. Skinner HD, Sandulache VC, Ow TJ, Meyn RE, Yordy JS, Beadle BM, Fitzgerald AL, Giri U, Ang KK, Myers JN. TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence. Clin Cancer Res. 2012 Jan 01; 18(1):290-300. PMID: 22090360; PMCID: PMC3251726.
      Citations: 126     Fields:    Translation:HumansAnimalsCells
    118. Sano D, Xie TX, Ow TJ, Zhao M, Pickering CR, Zhou G, Sandulache VC, Wheeler DA, Gibbs RA, Caulin C, Myers JN. Disruptive TP53 mutation is associated with aggressive disease characteristics in an orthotopic murine model of oral tongue cancer. Clin Cancer Res. 2011 Nov 01; 17(21):6658-70. PMID: 21903770; PMCID: PMC3207013.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    119. Zhou H, Sivasankar M, Kraus DH, Sandulache VC, Amin M, Branski RC. Glucocorticoids regulate extracellular matrix metabolism in human vocal fold fibroblasts. Laryngoscope. 2011 Sep; 121(9):1915-9. PMID: 22024844; PMCID: PMC3205428.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    120. Sandulache VC, Skinner HD, Ow TJ, Zhang A, Xia X, Luchak JM, Wong LJ, Pickering CR, Zhou G, Myers JN. Individualizing antimetabolic treatment strategies for head and neck squamous cell carcinoma based on TP53 mutational status. Cancer. 2012 Feb 01; 118(3):711-21. PMID: 21720999; PMCID: PMC3188683.
      Citations: 28     Fields:    Translation:HumansCells
    121. Zhou H, Felsen D, Sandulache VC, Amin MR, Kraus DH, Branski RC. Prostaglandin (PG)E2 exhibits antifibrotic activity in vocal fold fibroblasts. Laryngoscope. 2011 Jun; 121(6):1261-5. PMID: 21557245; PMCID: PMC3100449.
      Citations: 7     Fields:    Translation:HumansCells
    122. Sandulache VC, Myers JN. Altered metabolism in head and neck squamous cell carcinoma: an opportunity for identification of novel biomarkers and drug targets. Head Neck. 2012 Feb; 34(2):282-90. PMID: 21322078; PMCID: PMC3839242.
      Citations: 14     Fields:    Translation:HumansCells
    123. Frederick MJ, VanMeter AJ, Gadhikar MA, Henderson YC, Yao H, Pickering CC, Williams MD, El-Naggar AK, Sandulache V, Tarco E, Myers JN, Clayman GL, Liotta LA, Petricoin EF, Calvert VS, Fodale V, Wang J, Weber RS. Phosphoproteomic analysis of signaling pathways in head and neck squamous cell carcinoma patient samples. Am J Pathol. 2011 Feb; 178(2):548-71. PMID: 21281788; PMCID: PMC3070553.
      Citations: 16     Fields:    Translation:HumansCells
    124. Sandulache VC, Ow TJ, Pickering CR, Frederick MJ, Zhou G, Fokt I, Davis-Malesevich M, Priebe W, Myers JN. Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells. Cancer. 2011 Jul 01; 117(13):2926-38. PMID: 21692052; PMCID: PMC3135768.
      Citations: 64     Fields:    Translation:HumansCells
    125. Branski RC, Zhou H, Sandulache VC, Chen J, Felsen D, Kraus DH. Cyclooxygenase-2 signaling in vocal fold fibroblasts. Laryngoscope. 2010 Sep; 120(9):1826-31. PMID: 20717945; PMCID: PMC3132797.
      Citations: 9     Fields:    Translation:HumansCells
    126. Singh T, Sandulache VC, Otteson TD, Barsic M, Klein EC, Dohar JE, Hebda PA. Subglottic stenosis examined as a fibrotic response to airway injury characterized by altered mucosal fibroblast activity. Arch Otolaryngol Head Neck Surg. 2010 Feb; 136(2):163-70. PMID: 20157063; PMCID: PMC3000122.
      Citations: 17     Fields:    Translation:AnimalsCells
    127. Sandulache VC, Singh T, Li-Korotky HS, Lo CY, Otteson TD, Barsic M, Dohar JE, Hebda PA. Prostaglandin E2 is activated by airway injury and regulates fibroblast cytoskeletal dynamics. Laryngoscope. 2009 Jul; 119(7):1365-73. PMID: 19444894; PMCID: PMC3000119.
      Citations: 6     Fields:    Translation:AnimalsCells
    128. Parekh A, Sandulache VC, Singh T, Cetin S, Sacks MS, Dohar JE, Hebda PA. Prostaglandin E2 differentially regulates contraction and structural reorganization of anchored collagen gels by human adult and fetal dermal fibroblasts. Wound Repair Regen. 2009 Jan-Feb; 17(1):88-98. PMID: 19152655; PMCID: PMC3000117.
      Citations: 11     Fields:    Translation:HumansCells
    129. Defranco BH, Nickel BM, Baty CJ, Martinez JS, Gay VL, Sandulache VC, Hackam DJ, Murray SA. Migrating cells retain gap junction plaque structure and function. Cell Commun Adhes. 2008 Sep; 15(3):273-88. PMID: 18979295.
      Citations: 10     Fields:    Translation:HumansCells
    130. Otteson TD, Sandulache VC, Barsic M, Disilvio GM, Hebda PA, Dohar JE. Acute and chronic changes in the subglottis induced by graded carbon dioxide laser injury in the rabbit airway. Arch Otolaryngol Head Neck Surg. 2008 Jul; 134(7):694-702. PMID: 18645117; PMCID: PMC3000118.
      Citations: 7     Fields:    Translation:AnimalsCells
    131. Sandulache VC, Parekh A, Dohar JE, Hebda PA. Fetal dermal fibroblasts retain a hyperactive migratory and contractile phenotype under 2-and 3-dimensional constraints compared to normal adult fibroblasts. Tissue Eng. 2007 Nov; 13(11):2791-801. PMID: 17764403.
      Citations: 15     Fields:    Translation:HumansCells
    132. Agarwala SS, Cano E, Heron DE, Johnson J, Myers E, Sandulache V, Bahri S, Ferris R, Wang Y, Argiris A. Long-term outcomes with concurrent carboplatin, paclitaxel and radiation therapy for locally advanced, inoperable head and neck cancer. Ann Oncol. 2007 Jul; 18(7):1224-9. PMID: 17675395.
      Citations:    
    133. Parekh A, Sandulache VC, Lieb AS, Dohar JE, Hebda PA. Differential regulation of free-floating collagen gel contraction by human fetal and adult dermal fibroblasts in response to prostaglandin E2 mediated by an EP2/cAMP-dependent mechanism. Wound Repair Regen. 2007 May-Jun; 15(3):390-8. PMID: 17537126.
      Citations: 12     Fields:    Translation:HumansCells
    134. Chafin JB, Sandulache VC, Dunklebarger JL, Otteson TD, Hoffmann PJ, Hoffmann PA, Hebda PA, Dohar JE. Graded carbon dioxide laser-induced subglottic injury in the rabbit model. Arch Otolaryngol Head Neck Surg. 2007 Apr; 133(4):358-64. PMID: 17438250.
      Citations: 6     Fields:    Translation:Animals
    135. Sandulache VC, Chafin JB, Li-Korotky HS, Otteson TD, Dohar JE, Hebda PA. Elucidating the role of interleukin 1beta and prostaglandin E2 in upper airway mucosal wound healing. Arch Otolaryngol Head Neck Surg. 2007 Apr; 133(4):365-74. PMID: 17438251.
      Citations: 12     Fields:    Translation:Animals
    136. Sandulache VC, Parekh A, Li-Korotky H, Dohar JE, Hebda PA. Prostaglandin E2 inhibition of keloid fibroblast migration, contraction, and transforming growth factor (TGF)-beta1-induced collagen synthesis. Wound Repair Regen. 2007 Jan-Feb; 15(1):122-33. PMID: 17244328.
      Citations: 34     Fields:    Translation:HumansCells
    137. Sandulache VC, Parekh A, Li-Korotky HS, Dohar JE, Hebda PA. Prostaglandin E2 differentially modulates human fetal and adult dermal fibroblast migration and contraction: implication for wound healing. Wound Repair Regen. 2006 Sep-Oct; 14(5):633-43. PMID: 17014677.
      Citations: 19     Fields:    Translation:HumansCells
    138. Branski RC, Verdolini K, Sandulache V, Rosen CA, Hebda PA. Vocal fold wound healing: a review for clinicians. J Voice. 2006 Sep; 20(3):432-42. PMID: 16324825.
      Citations: 26     Fields:    Translation:HumansCells
    139. Sandulache VC, Dohar JE, Hebda PA. Fibroblast transplantation in the airway: implications for subglottic stenosis. Arch Otolaryngol Head Neck Surg. 2005 Dec; 131(12):1090-6. PMID: 16365223.
      Citations: 2     Fields:    Translation:AnimalsCells
    140. Qureshi FG, Ergun O, Sandulache VC, Nadler EP, Ford HR, Hackam DJ, Kane TD. Laparoscopic splenectomy in children. JSLS. 2005 Oct-Dec; 9(4):389-92. PMID: 16381351; PMCID: PMC3015648.
      Citations: 9     Fields:    Translation:Humans
    141. Branski RC, Sandulache VC, Dohar JE, Hebda PA. Mucosal wound healing in a rabbit model of subglottic stenosis: biochemical analysis of secretions. Arch Otolaryngol Head Neck Surg. 2005 Feb; 131(2):153-7. PMID: 15723948.
      Citations: 7     Fields:    Translation:Animals
    142. Qureshi FG, Sandulache VC, Richardson W, Ergun O, Ford HR, Hackam DJ. Primary vs delayed surgery for spontaneous pneumothorax in children: which is better? J Pediatr Surg. 2005 Jan; 40(1):166-9. PMID: 15868579.
      Citations: 8     Fields:    Translation:Humans
    143. Sandulache VC, Dohar JE, Hebda PA. Adult-fetal fibroblast interactions: effects on cell migration and implications for cell transplantation. Cell Transplant. 2005; 14(5):331-7. PMID: 16052914.
      Citations: 4     Fields:    Translation:AnimalsCells
    144. Sandulache VC, Zhou Z, Sherman A, Dohar JE, Hebda PA. Impact of transplanted fibroblasts on rabbit skin wounds. Arch Otolaryngol Head Neck Surg. 2003 Mar; 129(3):345-50. PMID: 12622547.
      Citations: 8     Fields:    Translation:AnimalsCells
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