Loading...
Header Logo
Keywords
Last Name
Institution

VLAD SANDULACHE

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Otolaryngology-Head and Neck Surgery
DivisionOtolaryngology
vCardDownload vCard

    Collapse ORNG Applications 
    Collapse Verify Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Piyarathna DWB, Balasubramanian A, Arnold JM, Lloyd SM, Karanam B, Castro P, Ittmann MM, Putluri N, Navone N, Jones JA, Yu W, Sandulache VC, Sikora AG, Michailidis G, Sreekumar A. ERR1 and PGC1a associated mitochondrial alterations correlate with pan-cancer disparity in African Americans. J Clin Invest. 2019 Mar 28; 130:2351-2356. PMID: 30920960.
      View in: PubMed
    2. Chen DW, Wang T, Shey-Sen Ni J, Sandulache VC, Graboyes EM, Worley M, Hornig JD, Skoner JM, Day TA, Huang AT. Prognostic factors associated with achieving total oral diet after glossectomy with microvascular free tissue transfer reconstruction. Oral Oncol. 2019 May; 92:59-66. PMID: 31010625.
      View in: PubMed
    3. Harms A, Kansara S, Stach C, Richardson PA, Chen G, Lai S, Sikora AG, Parke R, Donovan D, Chiao E, Skinner H, Sandulache VC. Swallowing Function in Survivors of Oropharyngeal Cancer Is Associated With Advanced T Classification. Ann Otol Rhinol Laryngol. 2019 Mar 27; 3489419839091. PMID: 30913911.
      View in: PubMed
    4. Badr H, Herbert K, Chhabria K, Sandulache VC, Chiao EY, Wagner T. Self-management intervention for head and neck cancer couples: Results of a randomized pilot trial. Cancer. 2019 Apr 01; 125(7):1176-1184. PMID: 30521075.
      View in: PubMed
    5. Richardson PA, Kansara S, Chen GG, Sabichi A, Sikora AG, Parke RB, Donovan DT, Chiao E, Sandulache VC. Treatment Patterns in Veterans with Laryngeal and Oropharyngeal Cancer and Impact on Survival. Laryngoscope Investig Otolaryngol. 2018 Aug; 3(4):275-282. PMID: 30186958.
      View in: PubMed
    6. Patel RS, Mohr T, Hartman C, Stach C, Sikora AG, Zevallos JP, Sandulache VC. Tracheoesophageal Prosthesis Use Is Associated With Improved Overall Quality of Life in Veterans With Laryngeal Cancer. Ann Otol Rhinol Laryngol. 2018 Jul; 127(7):421-428. PMID: 29756480.
      View in: PubMed
    7. Tam S, Sandulache VC, Metwalli KA, Rock CD, Eraj SA, Sheu T, El-Naggar AK, Fuller CD, Weber RS, Lai SY. Incompletely treated malignancies of the major salivary gland: Toward evidence-based care. Head Neck. 2018 08; 40(8):1630-1638. PMID: 29734482.
      View in: PubMed
    8. Yu W, Chen Y, Dubrulle J, Stossi F, Putluri V, Sreekumar A, Putluri N, Baluya D, Lai SY, Sandulache VC. Cisplatin generates oxidative stress which is accompanied by rapid shifts in central carbon metabolism. Sci Rep. 2018 Mar 09; 8(1):4306. PMID: 29523854.
      View in: PubMed
    9. Sandulache VC, Michikawa C, Kataria P, Gleber-Netto FO, Bell D, Trivedi S, Rao X, Wang J, Zhao M, Jasser S, Myers JN, Pickering CR. High-Risk TP53 Mutations Are Associated with Extranodal Extension in Oral Cavity Squamous Cell Carcinoma. Clin Cancer Res. 2018 04 01; 24(7):1727-1733. PMID: 29330202.
      View in: PubMed
    10. Krupar R, Hautmann MG, Pathak RR, Varier I, McLaren C, Gaag D, Hellerbrand C, Evert M, Laban S, Idel C, Sandulache V, Perner S, Bosserhoff AK, Sikora AG. Immunometabolic Determinants of Chemoradiotherapy Response and Survival in Head and Neck Squamous Cell Carcinoma. Am J Pathol. 2018 01; 188(1):72-83. PMID: 29107073.
      View in: PubMed
    11. Sandulache VC, Chen Y, Feng L, William WN, Skinner HD, Myers JN, Meyn RE, Li J, Mijiti A, Bankson JA, Fuller CD, Konopleva MY, Lai SY. Metabolic interrogation as a tool to optimize chemotherapeutic regimens. Oncotarget. 2017 Mar 14; 8(11):18154-18165. PMID: 28184025.
      View in: PubMed
    12. Rao SN, Zafereo M, Dadu R, Busaidy NL, Hess K, Cote GJ, Williams MD, William WN, Sandulache V, Gross N, Gunn GB, Lu C, Ferrarotto R, Lai SY, Cabanillas ME. Patterns of Treatment Failure in Anaplastic Thyroid Carcinoma. Thyroid. 2017 05; 27(5):672-681. PMID: 28068873.
      View in: PubMed
    13. Pezzi TA, Mohamed ASR, Sheu T, Blanchard P, Sandulache VC, Lai SY, Cabanillas ME, Williams MD, Pezzi CM, Lu C, Garden AS, Morrison WH, Rosenthal DI, Fuller CD, Gunn GB. Radiation therapy dose is associated with improved survival for unresected anaplastic thyroid carcinoma: Outcomes from the National Cancer Data Base. Cancer. 2017 05 01; 123(9):1653-1661. PMID: 28026871.
      View in: PubMed
    14. Sandulache VC, Williams MD, Lai SY, Lu C, William WN, Busaidy NL, Cote GJ, Singh RR, Luthra R, Cabanillas ME. Real-Time Genomic Characterization Utilizing Circulating Cell-Free DNA in Patients with Anaplastic Thyroid Carcinoma. Thyroid. 2017 01; 27(1):81-87. PMID: 27785980.
      View in: PubMed
    15. Sandulache VC, Vandelaar LJ, Skinner HD, Cata J, Hutcheson K, Fuller CD, Phan J, Siddiqui Z, Lai SY, Weber RS, Zafereo ME. Salvage total laryngectomy after external-beam radiotherapy: A 20-year experience. Head Neck. 2016 04; 38 Suppl 1:E1962-8. PMID: 26879395.
      View in: PubMed
    16. Pezzi TA, Sandulache VC, Pezzi CM, Turkeltaub AE, Feng L, Cabanillas ME, Williams MD, Lai SY. Treatment and survival of patients with insular thyroid carcinoma: 508 cases from the National Cancer Data Base. Head Neck. 2016 06; 38(6):906-12. PMID: 26843481.
      View in: PubMed
    17. Messer JA, Mohamed AS, Hutcheson KA, Ding Y, Lewin JS, Wang J, Lai SY, Frank SJ, Garden AS, Sandulache V, Eichelberger H, French CC, Colen RR, Phan J, Kalpathy-Cramer J, Hazle JD, Rosenthal DI, Gunn GB, Fuller CD. Magnetic resonance imaging of swallowing-related structures in nasopharyngeal carcinoma patients receiving IMRT: Longitudinal dose-response characterization of quantitative signal kinetics. Radiother Oncol. 2016 Feb; 118(2):315-22. PMID: 26830697.
      View in: PubMed
    18. Lai S, Wenaas AE, Sandulache VC, Hartman C, Chiao E, Kramer J, Zevallos JP. Prognostic Significance of p16 Cellular Localization in Oropharyngeal Squamous Cell Carcinoma. Ann Clin Lab Sci. 2016; 46(2):132-9. PMID: 27098618.
      View in: PubMed
    19. Bankson JA, Walker CM, Ramirez MS, Stefan W, Fuentes D, Merritt ME, Lee J, Sandulache VC, Chen Y, Phan L, Chou PC, Rao A, Yeung SC, Lee MH, Schellingerhout D, Conrad CA, Malloy C, Sherry AD, Lai SY, Hazle JD. Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors. Cancer Res. 2015 Nov 15; 75(22):4708-17. PMID: 26420214.
      View in: PubMed
    20. Sandulache VC, Chen Y, Skinner HD, Lu T, Feng L, Court LE, Myers JN, Meyn RE, Fuller CD, Bankson JA, Lai SY. Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model. Mol Cancer Ther. 2015 Dec; 14(12):2901-8. PMID: 26376962.
      View in: PubMed
    21. Lee J, Ramirez MS, Walker CM, Chen Y, Yi S, Sandulache VC, Lai SY, Bankson JA. High-throughput hyperpolarized (13)C metabolic investigations using a multi-channel acquisition system. J Magn Reson. 2015 Nov; 260:20-7. PMID: 26397217.
      View in: PubMed
    22. Sandulache VC, Hamblin J, Lai S, Pezzi T, Skinner HD, Khan NA, Dioun SM, Hartman C, Kramer J, Chiao E, Zhou X, Zevallos JP. Oropharyngeal squamous cell carcinoma in the veteran population: Association with traditional carcinogen exposure and poor clinical outcomes. Head Neck. 2015 Sep; 37(9):1246-53. PMID: 24801106.
      View in: PubMed
    23. Zevallos JP, Sandulache VC, Hamblin J, Skinner HD, Kramer J, Hartman CM, Horter KL, Lai S, Zhou X, Chiao EY. Impact of race on oropharyngeal squamous cell carcinoma presentation and outcomes among veterans. Head Neck. 2016 Jan; 38(1):44-50. PMID: 24992520.
      View in: PubMed
    24. Gelbard A, Francis DO, Sandulache VC, Simmons JC, Donovan DT, Ongkasuwan J. Causes and consequences of adult laryngotracheal stenosis. Laryngoscope. 2015 May; 125(5):1137-43. PMID: 25290987.
      View in: PubMed
    25. Zhou G, Wang J, Zhao M, Xie TX, Tanaka N, Sano D, Patel AA, Ward AM, Sandulache VC, Jasser SA, Skinner HD, Fitzgerald AL, Osman AA, Wei Y, Xia X, Songyang Z, Mills GB, Hung MC, Caulin C, Liang J, Myers JN. Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation. Mol Cell. 2014 Jun 19; 54(6):960-74. PMID: 24857548.
      View in: PubMed
    26. Sandulache VC, Kupferman ME. Transoral laser surgery for laryngeal cancer. Rambam Maimonides Med J. 2014 Apr; 5(2):e0012. PMID: 24808950.
      View in: PubMed
    27. Sandulache VC, Hamblin JS, Skinner HD, Kubik MW, Myers JN, Zevallos JP. Association between metformin use and improved survival in patients with laryngeal squamous cell carcinoma. Head Neck. 2014 Jul; 36(7):1039-43. PMID: 23784886.
      View in: PubMed
    28. Sandulache VC, Chen Y, Lee J, Rubinstein A, Ramirez MS, Skinner HD, Walker CM, Williams MD, Tailor R, Court LE, Bankson JA, Lai SY. Evaluation of hyperpolarized [1-¹³C]-pyruvate by magnetic resonance to detect ionizing radiation effects in real time. PLoS One. 2014; 9(1):e87031. PMID: 24475215.
      View in: PubMed
    29. Sandulache VC, Yang L, Skinner HD. Use of biguanides to improve response to chemotherapy. Methods Mol Biol. 2014; 1165:3-9. PMID: 24839014.
      View in: PubMed
    30. Woo SH, Sandulache VC, Yang L, Skinner HD. Evaluating response to metformin/cisplatin combination in cancer cells via metabolic measurement and clonogenic survival. Methods Mol Biol. 2014; 1165:11-8. PMID: 24839015.
      View in: PubMed
    31. Hamblin JS, Sandulache VC, Alapat PM, Takashima M. Management of obstructive sleep apnea in the indigent population: a deviation of standard of care? Otolaryngol Head Neck Surg. 2014 Mar; 150(3):346-7. PMID: 24316791.
      View in: PubMed
    32. Ramirez MS, Lee J, Walker CM, Sandulache VC, Hennel F, Lai SY, Bankson JA. Radial spectroscopic MRI of hyperpolarized [1-(13) C] pyruvate at 7 tesla. Magn Reson Med. 2014 Oct; 72(4):986-95. PMID: 24186845.
      View in: PubMed
    33. Ow TJ, Sandulache VC, Skinner HD, Myers JN. Integration of cancer genomics with treatment selection: from the genome to predictive biomarkers. Cancer. 2013 Nov 15; 119(22):3914-28. PMID: 24037788.
      View in: PubMed
    34. Sandulache VC, Kubik MW, Skinner HD, Malsky JA, Gelbard AH, Zevallos JP. Impact of race/ethnicity on laryngeal cancer in patients treated at a Veterans Affairs Medical Center. Laryngoscope. 2013 Sep; 123(9):2170-5. PMID: 23729204.
      View in: PubMed
    35. Skinner HD, Crane CH, Garrett CR, Eng C, Chang GJ, Skibber JM, Rodriguez-Bigas MA, Kelly P, Sandulache VC, Delclos ME, Krishnan S, Das P. Metformin use and improved response to therapy in rectal cancer. Cancer Med. 2013 Feb; 2(1):99-107. PMID: 24133632.
      View in: PubMed
    36. Cetin S, Tobey AB, Sandulache VC, Yang T, Barsic M, Lin Y, Dohar JE, Hebda PA. Cyclooxygenase-2 inhibition for the prevention of subglottic stenosis. Arch Otolaryngol Head Neck Surg. 2012 Oct; 138(10):962-8. PMID: 23069827.
      View in: PubMed
    37. Sandulache VC, Ow TJ, Daram SP, Hamilton J, Skinner H, Bell D, Rosenthal DI, Beadle BM, Ang KK, Kies MS, Johnson FM, El-Naggar AK, Myers JN. Residual nodal disease in patients with advanced-stage oropharyngeal squamous cell carcinoma treated with definitive radiation therapy and posttreatment neck dissection: Association with locoregional recurrence, distant metastasis, and decreased survival. Head Neck. 2013 Oct; 35(10):1454-60. PMID: 23018868.
      View in: PubMed
    38. Skinner HD, McCurdy MR, Echeverria AE, Lin SH, Welsh JW, O'Reilly MS, Hofstetter WL, Ajani JA, Komaki R, Cox JD, Sandulache VC, Myers JN, Guerrero TM. Metformin use and improved response to therapy in esophageal adenocarcinoma. Acta Oncol. 2013 Jun; 52(5):1002-9. PMID: 22950385.
      View in: PubMed
    39. Sandulache VC, Skinner HD, Wang Y, Chen Y, Dodge CT, Ow TJ, Bankson JA, Myers JN, Lai SY. Glycolytic inhibition alters anaplastic thyroid carcinoma tumor metabolism and improves response to conventional chemotherapy and radiation. Mol Cancer Ther. 2012 Jun; 11(6):1373-80. PMID: 22572813.
      View in: PubMed
    40. Skinner HD, Sandulache VC, Ow TJ, Meyn RE, Yordy JS, Beadle BM, Fitzgerald AL, Giri U, Ang KK, Myers JN. TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence. Clin Cancer Res. 2012 Jan 01; 18(1):290-300. PMID: 22090360.
      View in: PubMed
    41. Sano D, Xie TX, Ow TJ, Zhao M, Pickering CR, Zhou G, Sandulache VC, Wheeler DA, Gibbs RA, Caulin C, Myers JN. Disruptive TP53 mutation is associated with aggressive disease characteristics in an orthotopic murine model of oral tongue cancer. Clin Cancer Res. 2011 Nov 01; 17(21):6658-70. PMID: 21903770.
      View in: PubMed
    42. Zhou H, Sivasankar M, Kraus DH, Sandulache VC, Amin M, Branski RC. Glucocorticoids regulate extracellular matrix metabolism in human vocal fold fibroblasts. Laryngoscope. 2011 Sep; 121(9):1915-9. PMID: 22024844.
      View in: PubMed
    43. Sandulache VC, Skinner HD, Ow TJ, Zhang A, Xia X, Luchak JM, Wong LJ, Pickering CR, Zhou G, Myers JN. Individualizing antimetabolic treatment strategies for head and neck squamous cell carcinoma based on TP53 mutational status. Cancer. 2012 Feb 01; 118(3):711-21. PMID: 21720999.
      View in: PubMed
    44. Zhou H, Felsen D, Sandulache VC, Amin MR, Kraus DH, Branski RC. Prostaglandin (PG)E2 exhibits antifibrotic activity in vocal fold fibroblasts. Laryngoscope. 2011 Jun; 121(6):1261-5. PMID: 21557245.
      View in: PubMed
    45. Sandulache VC, Myers JN. Altered metabolism in head and neck squamous cell carcinoma: an opportunity for identification of novel biomarkers and drug targets. Head Neck. 2012 Feb; 34(2):282-90. PMID: 21322078.
      View in: PubMed
    46. Frederick MJ, VanMeter AJ, Gadhikar MA, Henderson YC, Yao H, Pickering CC, Williams MD, El-Naggar AK, Sandulache V, Tarco E, Myers JN, Clayman GL, Liotta LA, Petricoin EF, Calvert VS, Fodale V, Wang J, Weber RS. Phosphoproteomic analysis of signaling pathways in head and neck squamous cell carcinoma patient samples. Am J Pathol. 2011 Feb; 178(2):548-71. PMID: 21281788.
      View in: PubMed
    47. Sandulache VC, Ow TJ, Pickering CR, Frederick MJ, Zhou G, Fokt I, Davis-Malesevich M, Priebe W, Myers JN. Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells. Cancer. 2011 Jul 01; 117(13):2926-38. PMID: 21692052.
      View in: PubMed
    48. Branski RC, Zhou H, Sandulache VC, Chen J, Felsen D, Kraus DH. Cyclooxygenase-2 signaling in vocal fold fibroblasts. Laryngoscope. 2010 Sep; 120(9):1826-31. PMID: 20717945.
      View in: PubMed
    49. Singh T, Sandulache VC, Otteson TD, Barsic M, Klein EC, Dohar JE, Hebda PA. Subglottic stenosis examined as a fibrotic response to airway injury characterized by altered mucosal fibroblast activity. Arch Otolaryngol Head Neck Surg. 2010 Feb; 136(2):163-70. PMID: 20157063.
      View in: PubMed
    50. Sandulache VC, Singh T, Li-Korotky HS, Lo CY, Otteson TD, Barsic M, Dohar JE, Hebda PA. Prostaglandin E2 is activated by airway injury and regulates fibroblast cytoskeletal dynamics. Laryngoscope. 2009 Jul; 119(7):1365-73. PMID: 19444894.
      View in: PubMed
    51. Parekh A, Sandulache VC, Singh T, Cetin S, Sacks MS, Dohar JE, Hebda PA. Prostaglandin E2 differentially regulates contraction and structural reorganization of anchored collagen gels by human adult and fetal dermal fibroblasts. Wound Repair Regen. 2009 Jan-Feb; 17(1):88-98. PMID: 19152655.
      View in: PubMed
    52. Defranco BH, Nickel BM, Baty CJ, Martinez JS, Gay VL, Sandulache VC, Hackam DJ, Murray SA. Migrating cells retain gap junction plaque structure and function. Cell Commun Adhes. 2008 Sep; 15(3):273-88. PMID: 18979295.
      View in: PubMed
    53. Otteson TD, Sandulache VC, Barsic M, Disilvio GM, Hebda PA, Dohar JE. Acute and chronic changes in the subglottis induced by graded carbon dioxide laser injury in the rabbit airway. Arch Otolaryngol Head Neck Surg. 2008 Jul; 134(7):694-702. PMID: 18645117.
      View in: PubMed
    54. Sandulache VC, Parekh A, Dohar JE, Hebda PA. Fetal dermal fibroblasts retain a hyperactive migratory and contractile phenotype under 2-and 3-dimensional constraints compared to normal adult fibroblasts. Tissue Eng. 2007 Nov; 13(11):2791-801. PMID: 17764403.
      View in: PubMed
    55. Parekh A, Sandulache VC, Lieb AS, Dohar JE, Hebda PA. Differential regulation of free-floating collagen gel contraction by human fetal and adult dermal fibroblasts in response to prostaglandin E2 mediated by an EP2/cAMP-dependent mechanism. Wound Repair Regen. 2007 May-Jun; 15(3):390-8. PMID: 17537126.
      View in: PubMed
    56. Chafin JB, Sandulache VC, Dunklebarger JL, Otteson TD, Hoffmann PJ, Hoffmann PA, Hebda PA, Dohar JE. Graded carbon dioxide laser-induced subglottic injury in the rabbit model. Arch Otolaryngol Head Neck Surg. 2007 Apr; 133(4):358-64. PMID: 17438250.
      View in: PubMed
    57. Sandulache VC, Chafin JB, Li-Korotky HS, Otteson TD, Dohar JE, Hebda PA. Elucidating the role of interleukin 1beta and prostaglandin E2 in upper airway mucosal wound healing. Arch Otolaryngol Head Neck Surg. 2007 Apr; 133(4):365-74. PMID: 17438251.
      View in: PubMed
    58. Sandulache VC, Parekh A, Li-Korotky H, Dohar JE, Hebda PA. Prostaglandin E2 inhibition of keloid fibroblast migration, contraction, and transforming growth factor (TGF)-beta1-induced collagen synthesis. Wound Repair Regen. 2007 Jan-Feb; 15(1):122-33. PMID: 17244328.
      View in: PubMed
    59. Sandulache VC, Parekh A, Li-Korotky HS, Dohar JE, Hebda PA. Prostaglandin E2 differentially modulates human fetal and adult dermal fibroblast migration and contraction: implication for wound healing. Wound Repair Regen. 2006 Sep-Oct; 14(5):633-43. PMID: 17014677.
      View in: PubMed
    60. Branski RC, Verdolini K, Sandulache V, Rosen CA, Hebda PA. Vocal fold wound healing: a review for clinicians. J Voice. 2006 Sep; 20(3):432-42. PMID: 16324825.
      View in: PubMed
    61. Sandulache VC, Dohar JE, Hebda PA. Fibroblast transplantation in the airway: implications for subglottic stenosis. Arch Otolaryngol Head Neck Surg. 2005 Dec; 131(12):1090-6. PMID: 16365223.
      View in: PubMed
    62. Qureshi FG, Ergun O, Sandulache VC, Nadler EP, Ford HR, Hackam DJ, Kane TD. Laparoscopic splenectomy in children. JSLS. 2005 Oct-Dec; 9(4):389-92. PMID: 16381351.
      View in: PubMed
    63. Branski RC, Sandulache VC, Dohar JE, Hebda PA. Mucosal wound healing in a rabbit model of subglottic stenosis: biochemical analysis of secretions. Arch Otolaryngol Head Neck Surg. 2005 Feb; 131(2):153-7. PMID: 15723948.
      View in: PubMed
    64. Qureshi FG, Sandulache VC, Richardson W, Ergun O, Ford HR, Hackam DJ. Primary vs delayed surgery for spontaneous pneumothorax in children: which is better? J Pediatr Surg. 2005 Jan; 40(1):166-9. PMID: 15868579.
      View in: PubMed
    65. Sandulache VC, Dohar JE, Hebda PA. Adult-fetal fibroblast interactions: effects on cell migration and implications for cell transplantation. Cell Transplant. 2005; 14(5):331-7. PMID: 16052914.
      View in: PubMed
    66. Sandulache VC, Zhou Z, Sherman A, Dohar JE, Hebda PA. Impact of transplanted fibroblasts on rabbit skin wounds. Arch Otolaryngol Head Neck Surg. 2003 Mar; 129(3):345-50. PMID: 12622547.
      View in: PubMed
    SANDULACHE's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description