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JAVIER CHINEN

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
DivisionPediatrics-Allergy & Immunology
AddressONE BAYLOR PLAZA
HOUSTON TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Perez EE, Orange JS, Bonilla F, Chinen J, Chinn IK, Dorsey M, El-Gamal Y, Harville TO, Hossny E, Mazer B, Nelson R, Secord E, Jordan SC, Stiehm ER, Vo AA, Ballow M. Update on the use of immunoglobulin in human disease: A review of evidence. J Allergy Clin Immunol. 2016 Dec 24. PMID: 28041678.
      View in: PubMed
    2. Chinen J, Notarangelo LD, Shearer WT. Advances in clinical immunology in 2015. J Allergy Clin Immunol. 2016 Dec; 138(6):1531-1540. PMID: 27931534.
      View in: PubMed
    3. Stray-Pedersen A, Sorte HS, Samarakoon P, Gambin T, Chinn IK, Coban Akdemir ZH, Erichsen HC, Forbes LR, Gu S, Yuan B, Jhangiani SN, Muzny DM, Rødningen OK, Sheng Y, Nicholas SK, Noroski LM, Seeborg FO, Davis CM, Canter DL, Mace EM, Vece TJ, Allen CE, Abhyankar HA, Boone PM, Beck CR, Wiszniewski W, Fevang B, Aukrust P, Tjønnfjord GE, Gedde-Dahl T, Hjorth-Hansen H, Dybedal I, Nordøy I, Jørgensen SF, Abrahamsen TG, Øverland T, Bechensteen AG, Skogen V, Osnes LT, Kulseth MA, Prescott TE, Rustad CF, Heimdal KR, Belmont JW, Rider NL, Chinen J, Cao TN, Smith EA, Caldirola MS, Bezrodnik L, Lugo Reyes SO, Espinosa Rosales FJ, Guerrero-Cursaru ND, Pedroza LA, Poli CM, Franco JL, Trujillo Vargas CM, Aldave Becerra JC, Wright N, Issekutz TB, Issekutz AC, Abbott J, Caldwell JW, Bayer DK, Chan AY, Aiuti A, Cancrini C, Holmberg E, West C, Burstedt M, Karaca E, Yesil G, Artac H, Bayram Y, Atik MM, Eldomery MK, Ehlayel MS, Jolles S, Flatø B, Bertuch AA, Hanson IC, Zhang VW, Wong LJ, Hu J, Walkiewicz M, Yang Y, Eng CM, Boerwinkle E, Gibbs RA, Shearer WT, Lyle R, Orange JS, Lupski JR. Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders. J Allergy Clin Immunol. 2017 Jan; 139(1):232-245. PMID: 27577878.
      View in: PubMed
    4. Netter P, Chan SK, Banerjee PP, Monaco-Shawver L, Noroski LM, Hanson IC, Forbes LR, Mace EM, Chinen J, Gaspar HB, Sleiman P, Hakonarson H, Klein C, Ehlayel MS, Orange JS. A novel Rab27a mutation binds melanophilin, but not Munc13-4, causing immunodeficiency without albinism. J Allergy Clin Immunol. 2016 Mar 23. PMID: 27016801.
      View in: PubMed
    5. Bonilla FA, Khan DA, Ballas ZK, Chinen J, Frank MM, Hsu JT, Keller M, Kobrynski LJ, Komarow HD, Mazer B, Nelson RP, Orange JS, Routes JM, Shearer WT, Sorensen RU, Verbsky JW, Bernstein DI, Blessing-Moore J, Lang D, Nicklas RA, Oppenheimer J, Portnoy JM, Randolph CR, Schuller D, Spector SL, Tilles S, Wallace D. Practice parameter for the diagnosis and management of primary immunodeficiency. J Allergy Clin Immunol. 2015 Nov; 136(5):1186-205.e1-78. PMID: 26371839.
      View in: PubMed
    6. Chinen J, Notarangelo LD, Shearer WT. Advances in basic and clinical immunology in 2014. J Allergy Clin Immunol. 2015 May; 135(5):1132-41. PMID: 25956014.
      View in: PubMed
    7. Chinen J, Notarangelo LD, Shearer WT. Advances in basic and clinical immunology in 2013. J Allergy Clin Immunol. 2014 Apr; 133(4):967-76. PMID: 24589342; PMCID: PMC3988899.
    8. Chinen J, Notarangelo LD, Shearer WT. Advances in basic and clinical immunology in 2012. J Allergy Clin Immunol. 2013 Mar; 131(3):675-82. PMID: 23374612.
      View in: PubMed
    9. Orange JS, Ballow M, Stiehm ER, Ballas ZK, Chinen J, De La Morena M, Kumararatne D, Harville TO, Hesterberg P, Koleilat M, McGhee S, Perez EE, Raasch J, Scherzer R, Schroeder H, Seroogy C, Huissoon A, Sorensen RU, Katial R. Use and interpretation of diagnostic vaccination in primary immunodeficiency: a working group report of the Basic and Clinical Immunology Interest Section of the American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol. 2012 Sep; 130(3 Suppl):S1-24. PMID: 22935624.
      View in: PubMed
    10. Meller J, Malinin NL, Panigrahi S, Kerr BA, Patil A, Ma Y, Venkateswaran L, Rogozin IB, Mohandas N, Ehlayel MS, Podrez EA, Chinen J, Byzova TV. Novel aspects of Kindlin-3 function in humans based on a new case of leukocyte adhesion deficiency III. J Thromb Haemost. 2012 Jul; 10(7):1397-408. PMID: 22564402; PMCID: PMC3583563.
    11. Shroff P, Mehta RS, Chinen J, Karpen SJ, Davis CM. Presentation of atopic disease in a large cohort of pediatric liver transplant recipients. Pediatr Transplant. 2012 Jun; 16(4):379-84. PMID: 22489822.
      View in: PubMed
    12. Chinen J, Shearer WT. Advances in basic and clinical immunology in 2011. J Allergy Clin Immunol. 2012 Feb; 129(2):342-8. PMID: 22206779; PMCID: PMC3279946.
    13. Martinez CA, Shah S, Shearer WT, Rosenblatt HM, Paul ME, Chinen J, Leung KS, Kennedy-Nasser A, Brenner MK, Heslop HE, Liu H, Wu MF, Hanson IC, Krance RA. Excellent survival after sibling or unrelated donor stem cell transplantation for chronic granulomatous disease. J Allergy Clin Immunol. 2012 Jan; 129(1):176-83. PMID: 22078471.
      View in: PubMed
    14. Tison BE, Nicholas SK, Abramson SL, Hanson IC, Paul ME, Seeborg FO, Shearer WT, Perez MD, Noroski LM, Chinen J. Autoimmunity in a cohort of 130 pediatric patients with partial DiGeorge syndrome. J Allergy Clin Immunol. 2011 Nov; 128(5):1115-7.e1-3. PMID: 21835443.
      View in: PubMed
    15. Chinen J, Martinez-Gallo M, Gu W, Cols M, Cerutti A, Radigan L, Zhang L, Potocki L, Withers M, Lupski JR, Cunningham-Rundles C. Transmembrane activator and CAML interactor (TACI) haploinsufficiency results in B-cell dysfunction in patients with Smith-Magenis syndrome. J Allergy Clin Immunol. 2011 Jun; 127(6):1579-86. PMID: 21514638; PMCID: PMC3428026.
    16. Nicholas S, Krance RA, Hanson IC, Chinen J, Mamlok RJ, Roifman CM, Shearer WT. Early versus delayed diagnosis of SCID: triumph versus tragedy. Clin Immunol. 2011 Jun; 139(3):360-2. PMID: 21497138.
      View in: PubMed
    17. Ram G, Chinen J. Infections and immunodeficiency in Down syndrome. Clin Exp Immunol. 2011 Apr; 164(1):9-16. PMID: 21352207.
      View in: PubMed
    18. Chinen J, Shearer WT. Advances in basic and clinical immunology in 2010. J Allergy Clin Immunol. 2011 Feb; 127(2):336-41. PMID: 21281863; PMCID: PMC3057129.
    19. Okocha IU, Hanson CG, Chinen J, Shearer WT. Decline of antibodies in XLA infant: when to start IVIG. Allergy. 2011 Mar; 66(3):434-5. PMID: 21284651; PMCID: PMC3408709.
    20. Walter JE, Rucci F, Patrizi L, Recher M, Regenass S, Paganini T, Keszei M, Pessach I, Lang PA, Poliani PL, Giliani S, Al-Herz W, Cowan MJ, Puck JM, Bleesing J, Niehues T, Schuetz C, Malech H, DeRavin SS, Facchetti F, Gennery AR, Andersson E, Kamani NR, Sekiguchi J, Alenezi HM, Chinen J, Dbaibo G, ElGhazali G, Fontana A, Pasic S, Detre C, Terhorst C, Alt FW, Notarangelo LD. Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency. J Exp Med. 2010 Jul 5; 207(7):1541-54. PMID: 20547827.
      View in: PubMed
    21. Hill HR, Augustine NH, Pryor RJ, Reed GH, Bagnato JD, Tebo AE, Bender JM, Pasi BM, Chinen J, Hanson IC, de Boer M, Roos D, Wittwer CT. Rapid genetic analysis of x-linked chronic granulomatous disease by high-resolution melting. J Mol Diagn. 2010 May; 12(3):368-76. PMID: 20228266; PMCID: PMC2860474.
    22. Chinen J, Shearer WT. Advances in basic and clinical immunology in 2009. J Allergy Clin Immunol. 2010 Mar; 125(3):563-8. PMID: 20226292; PMCID: PMC2841291.
    23. Chinen J, Buckley RH. Transplantation immunology: solid organ and bone marrow. J Allergy Clin Immunol. 2010 Feb; 125(2 Suppl 2):S324-35. PMID: 20176267.
      View in: PubMed
    24. Lee SJ, Chinen J, Kavanaugh A. Immunomodulator therapy: monoclonal antibodies, fusion proteins, cytokines, and immunoglobulins. J Allergy Clin Immunol. 2010 Feb; 125(2 Suppl 2):S314-23. PMID: 20036416.
      View in: PubMed
    25. Chinen J, Shearer WT. Secondary immunodeficiencies, including HIV infection. J Allergy Clin Immunol. 2010 Feb; 125(2 Suppl 2):S195-203. PMID: 20042227.
      View in: PubMed
    26. Yong PL, Boyle J, Ballow M, Boyle M, Berger M, Bleesing J, Bonilla FA, Chinen J, Cunninghamm-Rundles C, Fuleihan R, Nelson L, Wasserman RL, Williams KC, Orange JS. Use of intravenous immunoglobulin and adjunctive therapies in the treatment of primary immunodeficiencies: A working group report of and study by the Primary Immunodeficiency Committee of the American Academy of Allergy Asthma and Immunology. Clin Immunol. 2010 May; 135(2):255-63. PMID: 19914873.
      View in: PubMed
    27. Patel NC, Chinen J, Rosenblatt HM, Hanson IC, Krance RA, Paul ME, Abramson SL, Noroski LM, Davis CM, Seeborg FO, Foster SB, Leung KS, Brown BS, Ritz J, Shearer WT. Outcomes of patients with severe combined immunodeficiency treated with hematopoietic stem cell transplantation with and without preconditioning. J Allergy Clin Immunol. 2009 Nov; 124(5):1062-9.e1-4. PMID: 19895994; PMCID: PMC3271026.
    28. Tantibhaedhyangkul U, Davis CM, Noroski LM, Hanson IC, Shearer WT, Chinen J. Role of IL-7 in the regulation of T-cell homeostasis in partial DiGeorge syndrome. J Allergy Clin Immunol. 2009 Apr; 123(4):960-2.e2. PMID: 19230961.
      View in: PubMed
    29. Chinen J, Shearer WT. Advances in basic and clinical immunology in 2008. J Allergy Clin Immunol. 2009 Feb; 123(2):328-32. PMID: 19203657.
      View in: PubMed
    30. Patel NC, Chinen J, Rosenblatt HM, Hanson IC, Brown BS, Paul ME, Abramson SL, Ritz J, Shearer WT. Long-term outcomes of nonconditioned patients with severe combined immunodeficiency transplanted with HLA-identical or haploidentical bone marrow depleted of T cells with anti-CD6 mAb. J Allergy Clin Immunol. 2008 Dec; 122(6):1185-93. PMID: 19084111.
      View in: PubMed
    31. Davis CM, Kancherla VS, Reddy A, Chan W, Yeh HW, Noroski LM, Rosenblatt H, Shearer WT, Chinen J. Development of specific T-cell responses to Candida and tetanus antigens in partial DiGeorge syndrome. J Allergy Clin Immunol. 2008 Dec; 122(6):1194-9. PMID: 18789819.
      View in: PubMed
    32. Chinen J, Shearer WT. Advances in basic and clinical immunology in 2007. J Allergy Clin Immunol. 2008 Jul; 122(1):36-41. PMID: 18514804.
      View in: PubMed
    33. Chinen J, Shearer WT. 6. Secondary immunodeficiencies, including HIV infection. J Allergy Clin Immunol. 2008 Feb; 121(2 Suppl):S388-92; quiz S417. PMID: 18241688.
      View in: PubMed
    34. Chinen J, Anmuth D, Franklin AR, Shearer WT. Long-term follow-up of patients with primary immunodeficiencies. J Allergy Clin Immunol. 2007 Oct; 120(4):795-7. PMID: 17854877.
      View in: PubMed
    35. Chinen J, Shearer WT. Advances in basic and clinical immunology in 2006. J Allergy Clin Immunol. 2007 Aug; 120(2):263-70. PMID: 17590425.
      View in: PubMed
    36. Chinen J, Davis J, De Ravin SS, Hay BN, Hsu AP, Linton GF, Naumann N, Nomicos EY, Silvin C, Ulrick J, Whiting-Theobald NL, Malech HL, Puck JM. Gene therapy improves immune function in preadolescents with X-linked severe combined immunodeficiency. Blood. 2007 Jul 1; 110(1):67-73. PMID: 17369490.
      View in: PubMed
    37. Chinen J, Shearer WT. Understanding the intricate network of signaling molecules. J Allergy Clin Immunol. 2007 Mar; 119(3):555-7. PMID: 17276502.
      View in: PubMed
    38. Chinen J, Finkelman F, Shearer WT. Advances in basic and clinical immunology. J Allergy Clin Immunol. 2006 Aug; 118(2):489-95. PMID: 16890776.
      View in: PubMed
    39. Orange JS, Hossny EM, Weiler CR, Ballow M, Berger M, Bonilla FA, Buckley R, Chinen J, El-Gamal Y, Mazer BD, Nelson RP, Patel DD, Secord E, Sorensen RU, Wasserman RL, Cunningham-Rundles C. Use of intravenous immunoglobulin in human disease: a review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and Immunology. J Allergy Clin Immunol. 2006 Apr; 117(4 Suppl):S525-53. PMID: 16580469.
      View in: PubMed
    40. Chinen J, Shearer WT. Basic and clinical immunology. J Allergy Clin Immunol. 2005 Aug; 116(2):411-8. PMID: 16083798.
      View in: PubMed
    41. Bonilla FA, Bernstein IL, Khan DA, Ballas ZK, Chinen J, Frank MM, Kobrynski LJ, Levinson AI, Mazer B, Nelson RP, Orange JS, Routes JM, Shearer WT, Sorensen RU. Practice parameter for the diagnosis and management of primary immunodeficiency. Ann Allergy Asthma Immunol. 2005 May; 94(5 Suppl 1):S1-63. PMID: 15945566.
      View in: PubMed
    42. Chinen J, Puck JM. Perspectives of gene therapy for primary immunodeficiencies. Curr Opin Allergy Clin Immunol. 2004 Dec; 4(6):523-7. PMID: 15640693.
      View in: PubMed
    43. Chinen J, Shearer WT. Subcutaneous immunoglobulins: alternative for the hypogammaglobulinemic patient? J Allergy Clin Immunol. 2004 Oct; 114(4):934-5. PMID: 15480338.
      View in: PubMed
    44. Chinen J, Shearer WT. Advances in asthma, allergy and immunology series 2004: basic and clinical immunology. J Allergy Clin Immunol. 2004 Aug; 114(2):398-405. PMID: 15316523.
      View in: PubMed
    45. Chinen J, Puck JM. Successes and risks of gene therapy in primary immunodeficiencies. J Allergy Clin Immunol. 2004 Apr; 113(4):595-603; quiz 604. PMID: 15100660.
      View in: PubMed
    46. Moylett EH, Chinen J, Shearer WT. Trichosporon pullulans infection in 2 patients with chronic granulomatous disease: an emerging pathogen and review of the literature. J Allergy Clin Immunol. 2003 Jun; 111(6):1370-4. PMID: 12789241.
      View in: PubMed
    47. Chinen J, Shearer WT. Basic and clinical immunology. J Allergy Clin Immunol. 2003 Mar; 111(3 Suppl):S813-8. PMID: 12618748.
      View in: PubMed
    48. Chinen J, Rosenblatt HM, Smith EO, Shearer WT, Noroski LM. Long-term assessment of T-cell populations in DiGeorge syndrome. J Allergy Clin Immunol. 2003 Mar; 111(3):573-9. PMID: 12642839.
      View in: PubMed
    49. Chinen J, Shearer WT. Molecular virology and immunology of HIV infection. J Allergy Clin Immunol. 2002 Aug; 110(2):189-98. PMID: 12170257.
      View in: PubMed
    50. Chinen J, Easley KA, Mendez H, Shearer WT. Decline of CD3-positive T-cell counts by 6 months of age is associated with rapid disease progression in HIV-1--infected infants. J Allergy Clin Immunol. 2001 Aug; 108(2):265-8. PMID: 11496244; PMCID: PMC4357165.
    51. Chinen J, Piecuch S. Anticonvulsant hypersensitivity syndrome vs Kawasaki disease: a challenging clinical diagnosis with therapeutic implications. Clin Pediatr (Phila). 2000 Feb; 39(2):109-11. PMID: 10696548.
      View in: PubMed
    52. Chinen J, Aguilar-Cordova E, Ng-Tang D, Lewis DE, Belmont JW. Protection of primary human T cells from HIV infection by Trev: a transdominant fusion gene. Hum Gene Ther. 1997 May 1; 8(7):861-8. PMID: 9143912.
      View in: PubMed
    53. Aguilar-Cordova E, Chinen J, Donehower LA, Harper JW, Rice AP, Butel JS, Belmont JW. Inhibition of HIV-1 by a double transdominant fusion gene. Gene Ther. 1995 May; 2(3):181-6. PMID: 7614248.
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    54. Aguilar-Cordova E, Chinen J, Donehower L, Lewis DE, Belmont JW. A sensitive reporter cell line for HIV-1 tat activity, HIV-1 inhibitors, and T cell activation effects. AIDS Res Hum Retroviruses. 1994 Mar; 10(3):295-301. PMID: 8018390.
      View in: PubMed
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