Header Logo

JAMES ORENGO

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Neurology
Address7200 CAMBRIDGE
Houston, TX 77030
vCardDownload vCard
    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neuroscience
    DivisionNeuroscience


    Collapse Research 
    Collapse research activities and funding
    R01NS129610     (ORENGO, JAMES P)Sep 1, 2023 - Aug 31, 2028
    NIH
    Investigating Motor Neuron Disease in Spinocerebellar Ataxia, Type1
    Role: Principal Investigator
    K08NS102396     (ORENGO, JAMES P)Aug 1, 2017 - Jul 31, 2022
    NIH
    Unraveling the mechanisms of motor neuron degeneration if Spinocerebellar Ataxia, type 1
    Role: Principal Investigator
    F30NS057884     (ORENGO, JAMES P)Feb 1, 2008 - Jan 31, 2011
    NIH
    Investigating mechanisms of skeletal muscle degeneration in Myotonic Dystrophy
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Polverino M, Sampaolo S, Capuozzo A, Fasolino M, Aliberti M, Satta E, Santoriello C, Orengo JP, Polverino F. Respiratory Function Changes as Early Signs of Amyotrophic Lateral Sclerosis. Respiration. 2023; 102(11):919-923. PMID: 37844546; PMCID: PMC10842422.
      Citations: 1     Fields:    Translation:Humans
    2. Sarasamma S, Karim A, Orengo JP. Zebrafish Models of Rare Neurological Diseases like Spinocerebellar Ataxias (SCAs): Advantages and Limitations. Biology (Basel). 2023 Oct 10; 12(10). PMID: 37887032; PMCID: PMC10604122.
      Citations:    
    3. Orengo JP, Nitschke L, van der Heijden ME, Ciaburri NA, Orr HT, Zoghbi HY. Reduction of mutant ATXN1 rescues premature death in a conditional SCA1 mouse model. JCI Insight. 2022 04 22; 7(8). PMID: 35290244; PMCID: PMC9089789.
      Citations:    Fields:    Translation:AnimalsCells
    4. Nitschke L, Coffin SL, Xhako E, El-Najjar DB, Orengo JP, Alcala E, Dai Y, Wan YW, Liu Z, Orr HT, Zoghbi HY. Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1. JCI Insight. 2021 02 08; 6(3). PMID: 33554954; PMCID: PMC7934855.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    5. Cope H, Spillmann R, Rosenfeld JA, Brokamp E, Signer R, Schoch K, Kelley EG, Sullivan JA, Macnamara E, Lincoln S, Golden-Grant K, Undiagnosed Diseases Network, Orengo JP, Clark G, Burrage LC, Posey JE, Punetha J, Robertson A, Cogan J, Phillips JA, Martinez-Agosto J, Shashi V. Missed diagnoses: Clinically relevant lessons learned through medical mysteries solved by the Undiagnosed Diseases Network. Mol Genet Genomic Med. 2020 10; 8(10):e1397. PMID: 32730690; PMCID: PMC7549585.
      Citations: 4     Fields:    Translation:Humans
    6. Orengo JP, van der Heijden ME, Hao S, Tang J, Orr HT, Zoghbi HY. Motor neuron degeneration correlates with respiratory dysfunction in SCA1. Dis Model Mech. 2018 02 26; 11(2). PMID: 29419414; PMCID: PMC5894948.
      Citations: 13     Fields:    Translation:AnimalsCells
    7. Orengo JP, Khemani P, Day JW, Li J, Siskind CE. Charcot Marie Tooth disease type 4J with complex central nervous system features. Ann Clin Transl Neurol. 2018 02; 5(2):222-225. PMID: 29468183; PMCID: PMC5817837.
      Citations: 5     Fields:    
    8. Muppidi S, Orengo JP, Lutz A. Overexertion-related focal ulnar neuropathy. Muscle Nerve. 2016 06; 53(6):989-91. PMID: 26663314.
      Citations: 1     Fields:    Translation:Humans
    9. Orengo JP, Pekmezci M, Cree BA. Simultaneous serum aquaporin-4 antibody and CSF NMDA receptor antibody-positive encephalitis. Neurol Neuroimmunol Neuroinflamm. 2015 Jun; 2(3):e101. PMID: 25884011; PMCID: PMC4396527.
      Citations: 1     Fields:    
    10. Alexandrescu S, Orengo JP, Toossi S, Perry A, Treseler P, Hess C, Margeta M. CNS intravascular large cell lymphoma in a patient with autoimmune hemolytic anemia. Neuropathology. 2015 Apr; 35(2):170-4. PMID: 25378202.
      Citations:    Fields:    Translation:Humans
    11. Orengo JP, Ward AJ, Cooper TA. Alternative splicing dysregulation secondary to skeletal muscle regeneration. Ann Neurol. 2011 Apr; 69(4):681-90. PMID: 21400563; PMCID: PMC3082633.
      Citations: 42     Fields:    Translation:AnimalsCells
    12. Orengo JP, Chambon P, Metzger D, Mosier DR, Snipes GJ, Cooper TA. Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2646-51. PMID: 18272483; PMCID: PMC2268190.
      Citations: 96     Fields:    Translation:AnimalsCells
    13. Orengo JP, Cooper TA. Alternative splicing in disease. Adv Exp Med Biol. 2007; 623:212-23. PMID: 18380349.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    14. Orengo JP, Bundman D, Cooper TA. A bichromatic fluorescent reporter for cell-based screens of alternative splicing. Nucleic Acids Res. 2006; 34(22):e148. PMID: 17142220; PMCID: PMC1669726.
      Citations: 47     Fields:    Translation:AnimalsCells
    ORENGO's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (100)
    Explore
    _
    Co-Authors (9)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _