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TIANHONG PAN

TitleInstructor
InstitutionMD Anderson
DepartmentOrthopaedic Oncology
Address1400 Pressler St
Houston TX 77030-4008
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Paindelli C, Parietti V, Barrios S, Shepherd P, Pan T, Wang WL, Satcher R, Logothetis CJ, Navone N, Campbell MT, Mikos AG, Dondossola E, Paindelli C, Parietti V, Barrios S, Shepherd P, Pan T, Wang WL, Satcher RL, Logothetis CJ, Navone N, Campbell MT, Mikos AG, Dondossola E. Bone mimetic environments support engineering, propagation, and analysis of therapeutic response of patient-derived cells, ex vivo and in vivo. Acta Biomater. 2024 Apr 01; 178:83-92. PMID: 38387748.
      Citations:    Fields:    
    2. Brozovich A, Garmezy B, Pan T, Wang L, Farach-Carson MC, Satcher RL. All bone metastases are not created equal: Revisiting treatment resistance in renal cell carcinoma. J Bone Oncol. 2021 Dec; 31:100399. PMID: 34745857; PMCID: PMC8551072.
      Citations: 2     
    3. Pan T, Lin SC, Lee YC, Yu G, Song JH, Pan J, Titus M, Satcher RL, Panaretakis T, Logothetis C, Yu-Lee LY, Lin SH. Statins reduce castration-induced bone marrow adiposity and prostate cancer progression in bone. Oncogene. 2021 07; 40(27):4592-4603. PMID: 34127814; PMCID: PMC8384136.
      Citations: 2     Fields:    Translation:Humans
    4. Yu G, Shen P, Lee YC, Pan J, Song JH, Pan T, Lin SC, Liang X, Wang G, Panaretakis T, Logothetis CJ, Gallick GE, Yu-Lee LY, Lin SH. Multiple pathways coordinating reprogramming of endothelial cells into osteoblasts by BMP4. iScience. 2021 Apr 23; 24(4):102388. PMID: 33981975; PMCID: PMC8086028.
      Citations: 1     
    5. Pan T, Martinez M, Hubka KM, Song JH, Lin SC, Yu G, Lee YC, Gallick GE, Tu SM, Harrington DA, Farach-Carson MC, Lin SH, Satcher RL. Cabozantinib Reverses Renal Cell Carcinoma-mediated Osteoblast Inhibition in Three-dimensional Coculture In Vitro and Reduces Bone Osteolysis In Vivo. Mol Cancer Ther. 2020 06; 19(6):1266-1278. PMID: 32220969; PMCID: PMC7272308.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    6. Yu-Lee LY, Lee YC, Pan J, Lin SC, Pan T, Yu G, Hawke DH, Pan BF, Lin SH. Bone secreted factors induce cellular quiescence in prostate cancer cells. Sci Rep. 2019 12 09; 9(1):18635. PMID: 31819067; PMCID: PMC6901558.
      Citations: 14     Fields:    Translation:HumansCells
    7. Yu-Lee LY, Yu G, Lee YC, Lin SC, Pan J, Pan T, Yu KJ, Liu B, Creighton CJ, Rodriguez-Canales J, Villalobos PA, Wistuba II, de Nadal E, Posas F, Gallick GE, Lin SH. Osteoblast-Secreted Factors Mediate Dormancy of Metastatic Prostate Cancer in the Bone via Activation of the TGF?RIII-p38MAPK-pS249/T252RB Pathway. Cancer Res. 2018 06 01; 78(11):2911-2924. PMID: 29514796; PMCID: PMC5984689.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    8. Pan T, Lin SC, Yu KJ, Yu G, Song JH, Lewis VO, Bird JE, Moon B, Lin PP, Tannir NM, Jonasch E, Wood CG, Gallick GE, Yu-Lee LY, Lin SH, Satcher RL. BIGH3 Promotes Osteolytic Lesions in Renal Cell Carcinoma Bone Metastasis by Inhibiting Osteoblast Differentiation. Neoplasia. 2018 01; 20(1):32-43. PMID: 29190493; PMCID: PMC5711998.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    9. Yu KJ, Li JK, Lee YC, Yu G, Lin SC, Pan T, Satcher RL, Titus MA, Yu-Lee LY, Weng WH, Gallick GE, Lin SH. Cabozantinib-induced osteoblast secretome promotes survival and migration of metastatic prostate cancer cells in bone. Oncotarget. 2017 Sep 26; 8(43):74987-75006. PMID: 29088840; PMCID: PMC5650395.
      Citations: 7     Fields:    
    10. Wan Y, Shi L, Wang Z, Sun G, Pan T, Zhang S, Zeng Y. Effective treatment via early cranioplasty for intractable contralateral subdural effusion after standard decompressive craniectomy in patients with severe traumatic brain injury. Clin Neurol Neurosurg. 2016 Oct; 149:87-93. PMID: 27500656.
      Citations:    
    11. Satcher RL, Pan T, Bilen MA, Li X, Lee YC, Ortiz A, Kowalczyk AP, Yu-Lee LY, Lin SH. Cadherin-11 endocytosis through binding to clathrin promotes cadherin-11-mediated migration in prostate cancer cells. J Cell Sci. 2015 Dec 15; 128(24):4629-41. PMID: 26519476; PMCID: PMC4696499.
      Citations: 13     Fields:    Translation:HumansCells
    12. Pan T, Fong EL, Martinez M, Harrington DA, Lin SH, Farach-Carson MC, Satcher RL. Three-dimensional (3D) culture of bone-derived human 786-O renal cell carcinoma retains relevant clinical characteristics of bone metastases. Cancer Lett. 2015 Aug 28; 365(1):89-95. PMID: 26004343; PMCID: PMC4530612.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    13. Feng Y, Liu T, Li XQ, Liu Y, Zhu XY, Jankovic J, Pan TH, Wu YC. Neuroprotection by Orexin-A via HIF-1a induction in a cellular model of Parkinson's disease. Neurosci Lett. 2014 Sep 05; 579:35-40. PMID: 25038418.
      Citations: 26     Fields:    Translation:HumansCells
    14. Zhu XY, Pan TH, Ondo WG, Jimenez-Shahed J, Wu YC. Effects of deep brain stimulation in relatively young-onset multiple system atrophy Parkinsonism. J Neurol Sci. 2014 Jul 15; 342(1-2):42-4. PMID: 24831987.
      Citations: 1     Fields:    Translation:Humans
    15. Satcher RL, Pan T, Cheng CJ, Lee YC, Lin SC, Yu G, Li X, Hoang AG, Tamboli P, Jonasch E, Gallick GE, Lin SH. Cadherin-11 in renal cell carcinoma bone metastasis. PLoS One. 2014; 9(2):e89880. PMID: 24587095; PMCID: PMC3933681.
      Citations: 19     Fields:    Translation:AnimalsCells
    16. Sun G, Wang X, Shi L, Yue X, Fu L, Chen C, Li Z, Pan T, Wan Z. Association between polymorphisms in interleukin-4Ra and interleukin-13 and glioma risk: a meta-analysis. Cancer Epidemiol. 2013 Jun; 37(3):306-10. PMID: 23395224.
      Citations:    
    17. Pan T, Zhu J, Hwu WJ, Jankovic J. The role of alpha-synuclein in melanin synthesis in melanoma and dopaminergic neuronal cells. PLoS One. 2012; 7(9):e45183. PMID: 23028833; PMCID: PMC3446957.
      Citations: 40     Fields:    Translation:HumansCells
    18. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bourquin JP, Boya P, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. PMID: 22966490; PMCID: PMC3404883.
      Citations: 1751     Fields:    Translation:HumansAnimals
    19. Wu Y, Li X, Zhu JX, Xie W, Le W, Fan Z, Jankovic J, Pan T. Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease. Neurosignals. 2011; 19(3):163-74. PMID: 21778691; PMCID: PMC3699815.
      Citations: 170     Fields:    Translation:HumansAnimalsCells
    20. Pan T, Li X, Jankovic J. The association between Parkinson's disease and melanoma. Int J Cancer. 2011 May 15; 128(10):2251-60. PMID: 21207412.
      Citations: 44     Fields:    Translation:Humans
    21. Wu Y, Davidson AL, Pan T, Jankovic J. Asian over-representation among patients with hemifacial spasm compared to patients with cranial-cervical dystonia. J Neurol Sci. 2010 Nov 15; 298(1-2):61-3. PMID: 20864122.
      Citations: 12     Fields:    Translation:Humans
    22. Li X, Lu Y, Pan T, Fan Z. Roles of autophagy in cetuximab-mediated cancer therapy against EGFR. Autophagy. 2010 Nov; 6(8):1066-77. PMID: 20864811; PMCID: PMC3039478.
      Citations: 47     Fields:    Translation:HumansCells
    23. Shi L, Chen J, Yang J, Pan T, Zhang S, Wang Z. MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity. Brain Res. 2010 Sep 17; 1352:255-64. PMID: 20633539.
      Citations:    
    24. Wu Y, Li X, Xie W, Jankovic J, Le W, Pan T. Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1 alpha and induction of autophagy in SH-SY5Y cells. Neurochem Int. 2010 Oct; 57(3):198-205. PMID: 20546814.
      Citations: 41     Fields:    Translation:HumansCells
    25. Shi L, Zhang J, Pan T, Zhou J, Gong W, Liu N, Fu Z, You Y. MiR-125b is critical for the suppression of human U251 glioma stem cell proliferation. Brain Res. 2010 Feb 02; 1312:120-6. PMID: 19948152.
      Citations:    
    26. Pan T, Rawal P, Wu Y, Xie W, Jankovic J, Le W. Rapamycin protects against rotenone-induced apoptosis through autophagy induction. Neuroscience. 2009 Dec 01; 164(2):541-51. PMID: 19682553.
      Citations: 110     Fields:    Translation:HumansCells
    27. Le W, Pan T, Huang M, Xu P, Xie W, Zhu W, Zhang X, Deng H, Jankovic J. Decreased NURR1 gene expression in patients with Parkinson's disease. J Neurol Sci. 2008 Oct 15; 273(1-2):29-33. PMID: 18684475; PMCID: PMC2572302.
      Citations: 56     Fields:    Translation:Humans
    28. Pan T, Kondo S, Zhu W, Xie W, Jankovic J, Le W. Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement. Neurobiol Dis. 2008 Oct; 32(1):16-25. PMID: 18640276.
      Citations: 94     Fields:    Translation:AnimalsCells
    29. Pan T, Zhu W, Zhao H, Deng H, Xie W, Jankovic J, Le W. Nurr1 deficiency predisposes to lactacystin-induced dopaminergic neuron injury in vitro and in vivo. Brain Res. 2008 Jul 30; 1222:222-9. PMID: 18579122.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    30. Li X, Lu Y, Liang K, Pan T, Mendelsohn J, Fan Z. Requirement of hypoxia-inducible factor-1alpha down-regulation in mediating the antitumor activity of the anti-epidermal growth factor receptor monoclonal antibody cetuximab. Mol Cancer Ther. 2008 May; 7(5):1207-17. PMID: 18483308.
      Citations: 37     Fields:    Translation:HumansCells
    31. Zhu W, Xie W, Pan T, Jankovic J, Li J, Youdim MB, Le W. Comparison of neuroprotective and neurorestorative capabilities of rasagiline and selegiline against lactacystin-induced nigrostriatal dopaminergic degeneration. J Neurochem. 2008 Jun; 105(5):1970-8. PMID: 18399960.
      Citations: 21     Fields:    Translation:Animals
    32. Wang W, Le WD, Pan T, Stringer JL, Jaiswal AK. Association of NRH:quinone oxidoreductase 2 gene promoter polymorphism with higher gene expression and increased susceptibility to Parkinson's disease. J Gerontol A Biol Sci Med Sci. 2008 Feb; 63(2):127-34. PMID: 18314446.
      Citations: 9     Fields:    Translation:HumansCells
    33. Pan T, Kondo S, Le W, Jankovic J. The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease. Brain. 2008 Aug; 131(Pt 8):1969-78. PMID: 18187492.
      Citations: 214     Fields:    Translation:HumansCells
    34. Zhu W, Xie W, Pan T, Xu P, Fridkin M, Zheng H, Jankovic J, Youdim MB, Le W. Prevention and restoration of lactacystin-induced nigrostriatal dopamine neuron degeneration by novel brain-permeable iron chelators. FASEB J. 2007 Dec; 21(14):3835-44. PMID: 17690154.
      Citations: 37     Fields:    Translation:AnimalsCells
    35. Deng H, Le W, Huang M, Xie W, Pan T, Jankovic J. Genetic analysis of LRRK2 P755L variant in Caucasian patients with Parkinson's disease. Neurosci Lett. 2007 May 29; 419(2):104-7. PMID: 17482357.
      Citations: 4     Fields:    Translation:Humans
    36. Zhao H, Zhu W, Pan T, Xie W, Zhang A, Ondo WG, Le W. Spinal cord dopamine receptor expression and function in mice with 6-OHDA lesion of the A11 nucleus and dietary iron deprivation. J Neurosci Res. 2007 Apr; 85(5):1065-76. PMID: 17342757.
      Citations: 26     Fields:    Translation:AnimalsCells
    37. Pan T, Li X, Xie W, Jankovic J, Le W. Valproic acid-mediated Hsp70 induction and anti-apoptotic neuroprotection in SH-SY5Y cells. FEBS Lett. 2005 Dec 19; 579(30):6716-20. PMID: 16313906.
      Citations: 26     Fields:    Translation:HumansCells
    38. Zhang X, Xie W, Qu S, Pan T, Wang X, Le W. Neuroprotection by iron chelator against proteasome inhibitor-induced nigral degeneration. Biochem Biophys Res Commun. 2005 Jul 29; 333(2):544-9. PMID: 15950935.
      Citations: 25     Fields:    Translation:Animals
    39. Qu S, Ondo WG, Zhang X, Xie WJ, Pan TH, Le WD. Projections of diencephalic dopamine neurons into the spinal cord in mice. Exp Brain Res. 2006 Jan; 168(1-2):152-6. PMID: 16044299.
      Citations: 46     Fields:    Translation:AnimalsCells
    40. Deng H, Le WD, Zhang X, Pan TH, Jankovic J. G309D and W437OPA PINK1 mutations in Caucasian Parkinson's disease patients. Acta Neurol Scand. 2005 Jun; 111(6):351-2. PMID: 15876334.
      Citations: 1     Fields:    Translation:Humans
    41. Deng H, Le WD, Xie WJ, Pan TH, Zhang X, Jankovic J. Genetic analysis of parkin co-regulated gene (PACRG) in patients with early-onset parkinsonism. Neurosci Lett. 2005 Jul 15; 382(3):297-9. PMID: 15925106.
      Citations: 2     Fields:    Translation:Humans
    42. Cai W, Khaoustov VI, Xie Q, Pan T, Le W, Yoffe B. Interferon-alpha-induced modulation of glucocorticoid and serotonin receptors as a mechanism of depression. J Hepatol. 2005 Jun; 42(6):880-7. PMID: 15885359.
      Citations: 26     Fields:    Translation:HumansCells
    43. Pan T, Xie W, Jankovic J, Le W. Biological effects of pramipexole on dopaminergic neuron-associated genes: relevance to neuroprotection. Neurosci Lett. 2005 Mar 29; 377(2):106-9. PMID: 15740846.
      Citations: 16     Fields:    Translation:HumansCells
    44. Jiang C, Wan X, He Y, Pan T, Jankovic J, Le W. Age-dependent dopaminergic dysfunction in Nurr1 knockout mice. Exp Neurol. 2005 Jan; 191(1):154-62. PMID: 15589522.
      Citations: 48     Fields:    Translation:Animals
    45. Rachakonda V, Pan TH, LE WD. Biomarkers of neurodegenerative disorders: how good are they? Cell Res. 2004 Oct; 14(5):347-58. PMID: 15538967.
      Citations: 32     Fields:    Translation:HumansAnimals
    46. Henkel JS, Engelhardt JI, Simpson EP, Kim SH, Pan T, Goodman JC, Siddique T, Beers DR, Appel SH, Sikl?s L. Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Ann Neurol. 2004 Feb; 55(2):221-35. PMID: 14755726.
      Citations: 207     Fields:    Translation:HumansCells
    47. Pan T, Le W, Jankovic J. Slowing Parkinson's disease progression: recent dopamine agonist trials. Neurology. 2004 Jan 27; 62(2):343; author reply 343-4. PMID: 14750218.
      Citations: 1     Fields:    Translation:HumansCells
    48. Pan T, Fei J, Zhou X, Jankovic J, Le W. Effects of green tea polyphenols on dopamine uptake and on MPP+ -induced dopamine neuron injury. Life Sci. 2003 Jan 17; 72(9):1073-83. PMID: 12495785.
      Citations: 15     Fields:    Translation:AnimalsCells
    49. Pan T, Jankovic J, Le W. Potential therapeutic properties of green tea polyphenols in Parkinson's disease. Drugs Aging. 2003; 20(10):711-21. PMID: 12875608.
      Citations: 26     Fields:    Translation:HumansAnimals
    50. Slowing Parkinson's disease progression. Neurology. 62:343-345.
    51. Cadherin-11 endocytosis through binding to clathrin promotes cadherin-11-mediated migration in prostate cancer cells. Journal of Cell Science. 128:4629-4641.
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