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HONG WEN

TitleAssistant Professor
InstitutionMD Anderson
DepartmentEpigenetics & Molecular Carcinogenesis
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wen H, Li Y, Xi Y, Jiang S, Stratton S, Peng D, Tanaka K, Ren Y, Xia Z, Wu J, Li B, Barton MC, Li W, Li H, Shi X. ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression. Nature. 2014 Apr 10; 508(7495):263-8. PMID: 24590075.
      View in: PubMed
    2. Klein BJ, Piao L, Xi Y, Rincon-Arano H, Rothbart SB, Peng D, Wen H, Larson C, Zhang X, Zheng X, Cortazar MA, Peña PV, Mangan A, Bentley DL, Strahl BD, Groudine M, Li W, Shi X, Kutateladze TG. The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers. Cell Rep. 2014 Jan 30; 6(2):325-35. PMID: 24412361.
      View in: PubMed
    3. Zhang X, Tanaka K, Yan J, Li J, Peng D, Jiang Y, Yang Z, Barton MC, Wen H, Shi X. Regulation of estrogen receptor a by histone methyltransferase SMYD2-mediated protein methylation. Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43):17284-9. PMID: 24101509.
      View in: PubMed
    4. DeBruhl H, Wen H, Lipsick JS. The complex containing Drosophila Myb and RB/E2F2 regulates cytokinesis in a histone H2Av-dependent manner. Mol Cell Biol. 2013 May; 33(9):1809-18. PMID: 23438598.
      View in: PubMed
    5. Zhang X, Wen H, Shi X. Lysine methylation: beyond histones. Acta Biochim Biophys Sin (Shanghai). 2012 Jan; 44(1):14-27. PMID: 22194010.
      View in: PubMed
    6. Andrejka L, Wen H, Ashton J, Grant M, Iori K, Wang A, Manak JR, Lipsick JS. Animal-specific C-terminal domain links myeloblastosis oncoprotein (Myb) to an ancient repressor complex. Proc Natl Acad Sci U S A. 2011 Oct 18; 108(42):17438-43. PMID: 21969598.
      View in: PubMed
    7. Ouyang Y, Petritsch C, Wen H, Jan L, Jan YN, Lu B. Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila. Development. 2011 Jun; 138(11):2185-96. PMID: 21558368.
      View in: PubMed
    8. Chang JY, Komaki R, Lu C, Wen HY, Allen PK, Tsao A, Gillin M, Mohan R, Cox JD. Phase 2 study of high-dose proton therapy with concurrent chemotherapy for unresectable stage III nonsmall cell lung cancer. Cancer. 2011 Oct 15; 117(20):4707-13. PMID: 21437893.
      View in: PubMed
    9. Wen H, Li J, Song T, Lu M, Kan PY, Lee MG, Sha B, Shi X. Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation. J Biol Chem. 2010 Mar 26; 285(13):9322-6. PMID: 20129925.
      View in: PubMed
    10. Kachirskaia I, Shi X, Yamaguchi H, Tanoue K, Wen H, Wang EW, Appella E, Gozani O. Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling. J Biol Chem. 2008 Dec 12; 283(50):34660-6. PMID: 18840612.
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    11. Wen H, Andrejka L, Ashton J, Karess R, Lipsick JS. Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF via the Myb-MuvB/dREAM complex. Genes Dev. 2008 Mar 01; 22(5):601-14. PMID: 18316477.
      View in: PubMed
    12. Shi X, Kachirskaia I, Yamaguchi H, West LE, Wen H, Wang EW, Dutta S, Appella E, Gozani O. Modulation of p53 function by SET8-mediated methylation at lysine 382. Mol Cell. 2007 Aug 17; 27(4):636-46. PMID: 17707234.
      View in: PubMed
    13. Manak JR, Wen H, Van T, Andrejka L, Lipsick JS. Loss of Drosophila Myb interrupts the progression of chromosome condensation. Nat Cell Biol. 2007 May; 9(5):581-7. PMID: 17450131.
      View in: PubMed
    14. Wang DM, Sevcikova S, Wen H, Roberts S, Lipsick JS. v-Myb represses the transcription of Ets-2. Oncogene. 2007 Feb 22; 26(8):1238-44. PMID: 16909100.
      View in: PubMed
    15. Huang J, Meyer JS, Zhang Z, Wei J, Hong X, Wang J, Wen H, Wu W, Wu J, Chowdhury MH. Progression of mild cognitive impairment to Alzheimer's or vascular dementia versus normative aging among elderly Chinese. Curr Alzheimer Res. 2005 Dec; 2(5):571-8. PMID: 16375660.
      View in: PubMed
    16. Wen H, Ao S. Identification and characterization of a novel human cDNA encoding a 21 kDa pRb-associated protein. Gene. 2001 Jan 24; 263(1-2):85-92. PMID: 11223246.
      View in: PubMed
    17. Wen H, Ao S. RBP95, a novel leucine zipper protein, binds to the retinoblastoma protein. Biochem Biophys Res Commun. 2000 Aug 18; 275(1):141-8. PMID: 10944455.
      View in: PubMed
    18. Zhou R, Wen H, Ao SZ. Identification of a novel gene encoding a p53-associated protein. Gene. 1999 Jul 22; 235(1-2):93-101. PMID: 10415337.
      View in: PubMed
    19. YEATS2 is a selective histone crotonylation reader. Cell Research. 26:629-632.
    20. Identification and cloning of the cDNA of a Rb-associated protein RAP140a. Science in China, Series C: Life Sciences. 43:645-647.
    21. Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain. Molecular Cell. 62:181-193.
    22. The Histone Variant H3.3 in Transcriptional Regulation and Human Disease. Journal of Molecular Biology.
    23. ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes. Molecular Cell.
    24. G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression. Nature Communications. 7.
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