LEI NIE

TitleAssistant Professor
InstitutionMD Anderson
DepartmentMolecular & Cellular Oncology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wei Y, Nie L, Gao L, Zhong L, Sun Z, Yang X, Yue J, Zeng Y, Li L, Sun J, Zang H. An Integrated Strategy to Identify and Quantify the Quality Markers of Xinkeshu Tablets Based on Spectrum-Effect Relationship, Network Pharmacology, Plasma Pharmacochemistry, and Pharmacodynamics of Zebrafish. Front Pharmacol. 2022; 13:899038. PMID: 35677447.
      Citations:    
    2. Jiang VC, Liu Y, Jordan A, Leeming A, McIntosh J, Huang S, Zhang R, Cai Q, Chen Z, Li Y, Che Y, Nie L, Karlsson I, Mårtensson L, Kovacek M, Teige I, Frendéus B, Wang M. Targeting Fc?RIIB by antagonistic antibody BI-1206 improves the efficacy of rituximab-based therapies in aggressive mantle cell lymphoma. J Hematol Oncol. 2022 04 11; 15(1):42. PMID: 35410313.
      Citations:    Fields:    Translation:HumansAnimals
    3. Nie L, Wang W, Deng L, He W. ANN and LEFM-Based Fatigue Reliability Analysis and Truck Weight Limits of Steel Bridges after Crack Detection. Sensors (Basel). 2022 Feb 17; 22(4). PMID: 35214480.
      Citations: 1     Fields:    
    4. Zabor EC, Kane MJ, Roychoudhury S, Nie L, Hobbs BP. Bayesian basket trial design with false-discovery rate control. Clin Trials. 2022 Feb 07; 17407745211073624. PMID: 35128970.
      Citations:    Fields:    Translation:Humans
    5. Zhang F, Xiang S, Cao Y, Li M, Ma Q, Liang H, Li H, Ye Y, Zhang Y, Jiang L, Hu Y, Zhou J, Wang X, Zhang Y, Nie L, Liang X, Gong W, Liu Y. Correction: EIF3D promotes gallbladder cancer development by stabilizing GRK2 kinase and activating PI3K-AKT signaling pathway. Cell Death Dis. 2021 Dec 20; 13(1):19. PMID: 34930898.
      Citations:    Fields:    
    6. Fu C, Nie L, Yin T, Xu X, Lu W. LncRNA EPIC1 promotes proliferation and inhibits apoptosis of gallbladder cancer cells by interacting with LET. Ann Hepatol. 2021 Dec; 26:100563. PMID: 34653690.
      Citations:    Fields:    Translation:HumansCells
    7. Gao ZZ, Li C, Chen G, Yuan JJ, Zhou YQ, Jiao JY, Nie L, Qi J, Yang Y, Chen SQ, Wang HB. Optimization strategies for expression of a novel bifunctional anti-PD-L1/TGFBR2-ECD fusion protein. Protein Expr Purif. 2022 01; 189:105973. PMID: 34560256.
      Citations:    Fields:    Translation:HumansAnimalsCells
    8. Jiang L, Nie L, Yuan Y. Elastic priors to dynamically borrow information from historical data in clinical trials. Biometrics. 2021 Aug 26. PMID: 34437714.
      Citations:    Fields:    
    9. Zhang QZ, Wen F, Yang HL, Cao YY, Peng RG, Wang YM, Nie L, Qin YK, Wu JJ, Zhao X, Zi D. GADD45a alleviates the CDDP resistance of SK-OV3/cddp cells via redox-mediated DNA damage. Oncol Lett. 2021 Oct; 22(4):720. PMID: 34429760.
      Citations:    
    10. Jiang L, Nie L, Yan F, Yuan Y. Optimal Bayesian hierarchical model to accelerate the development of tissue-agnostic drugs and basket trials. Contemp Clin Trials. 2021 08; 107:106460. PMID: 34098036.
      Citations:    Fields:    Translation:Humans
    11. Nie L, Dai K, Wu J, Zhou X, Hu J, Zhang C, Zhan Y, Song Y, Fan W, Hu Z, Yang H, Yang Q, Wu D, Li F, Li D, Nie R. Clinical characteristics and risk factors for in-hospital mortality of lung cancer patients with COVID-19: A multicenter, retrospective, cohort study. Thorac Cancer. 2021 01; 12(1):57-65. PMID: 33142039.
      Citations: 8     Fields:    Translation:HumansCells
    12. Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC. Author Correction: PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. Nat Cell Biol. 2020 Nov; 22(11):1396. PMID: 33033376.
      Citations: 4     Fields:    
    13. He Y, Xu Y, Lv Y, Nie L, Wang H. Soil Bacterial Community Structure in Turfy Swamp and Its Response to Highway Disturbance. Int J Environ Res Public Health. 2020 10 26; 17(21). PMID: 33114604.
      Citations: 1     Fields:    Translation:PHPublic Health
    14. Liang Y, Ma Y, Wang J, Nie L, Hou X, Wu W, Zhang X, Tian Y. Leptin Contributes to Neuropathic Pain via Extrasynaptic NMDAR-nNOS Activation. Mol Neurobiol. 2021 Mar; 58(3):1185-1195. PMID: 33099751.
      Citations: 2     Fields:    Translation:AnimalsCells
    15. Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC. PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. Nat Cell Biol. 2020 10; 22(10):1264-1275. PMID: 32929201.
      Citations: 100     Fields:    Translation:HumansAnimalsCells
    16. Nie L, Li C, Zhao T, Wang Y, Liu J. LncRNA double homeobox A pseudogene 8 (DUXAP8) facilitates the progression of neuroblastoma and activates Wnt/ß-catenin pathway via microRNA-29/nucleolar protein 4 like (NOL4L) axis. Brain Res. 2020 11 01; 1746:146947. PMID: 32522628.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    17. Han Y, Wei Y, Yao J, Chu YY, Li CW, Hsu JL, Nie L, Hung MC. Inhibition of CDK2 reduces EZH2 phosphorylation and reactivates ERa expression in high-grade serous ovarian carcinoma. Am J Cancer Res. 2020; 10(4):1194-1206. PMID: 32368395.
      Citations: 4     
    18. Chu YY, Yam C, Chen MK, Chan LC, Xiao M, Wei YK, Yamaguchi H, Lee PC, Han Y, Nie L, Sun X, Moulder SL, Hess KR, Wang B, Hsu JL, Hortobagyi GN, Litton J, Chang JT, Hung MC. Blocking c-Met and EGFR reverses acquired resistance of PARP inhibitors in triple-negative breast cancer. Am J Cancer Res. 2020; 10(2):648-661. PMID: 32195033.
      Citations: 15     
    19. Nie L, Wei Y, Zhang F, Hsu YH, Chan LC, Xia W, Ke B, Zhu C, Deng R, Tang J, Yao J, Chu YY, Zhao X, Han Y, Hou J, Huo L, Ko HW, Lin WC, Yamaguchi H, Hsu JM, Yang Y, Pan DN, Hsu JL, Kleer CG, Davidson NE, Hortobagyi GN, Hung MC. Author Correction: CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer. Nat Commun. 2020 Jan 29; 11(1):673. PMID: 31996688.
      Citations: 1     Fields:    
    20. Wang T, Yang N, Liang C, Xu H, An Y, Xiao S, Zheng M, Liu L, Wang G, Nie L. Detecting Protein-Protein Interaction Based on Protein Fragment Complementation Assay. Curr Protein Pept Sci. 2020; 21(6):598-610. PMID: 32053071.
      Citations: 3     Fields:    Translation:AnimalsCells
    21. Yang Q, Ai W, Nie L, Yan C, Wu S. Vildagliptin reduces myocardial ischemia-induced arrhythmogenesis via modulating inflammatory responses and promoting expression of genes regulating mitochondrial biogenesis in rats with type-II diabetes. J Interv Card Electrophysiol. 2020 Dec; 59(3):517-526. PMID: 31853804.
      Citations:    Fields:    Translation:Animals
    22. Hu X, Zhang G, Nie L, Kong T, Lei A. Electrochemical oxidation induced intermolecular aromatic C-H imidation. Nat Commun. 2019 11 29; 10(1):5467. PMID: 31784522.
      Citations: 5     Fields:    
    23. Nie L, Wei Y, Zhang F, Hsu YH, Chan LC, Xia W, Ke B, Zhu C, Deng R, Tang J, Yao J, Chu YY, Zhao X, Han Y, Hou J, Huo L, Ko HW, Lin WC, Yamaguchi H, Hsu JM, Yang Y, Pan DN, Hsu JL, Kleer CG, Davidson NE, Hortobagyi GN, Hung MC. CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer. Nat Commun. 2019 11 08; 10(1):5114. PMID: 31704972.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    24. Wen F, Wu ZY, Nie L, Zhang QZ, Qin YK, Zhou ZL, Wu JJ, Zhao X, Tan J, Sawmiller D, Zi D. Eukaryotic initiation factor 3, subunit C silencing inhibits cell proliferation and promotes apoptosis in human ovarian cancer cells. Biosci Rep. 2019 08 30; 39(8). PMID: 31316002.
      Citations: 4     Fields:    Translation:HumansCells
    25. Kasamon YL, Chen H, de Claro RA, Nie L, Ye J, Blumenthal GM, Farrell AT, Pazdur R. FDA Approval Summary: Mogamulizumab-kpkc for Mycosis Fungoides and Sézary Syndrome. Clin Cancer Res. 2019 12 15; 25(24):7275-7280. PMID: 31366601.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    26. Chan LC, Li CW, Xia W, Hsu JM, Lee HH, Cha JH, Wang HL, Yang WH, Yen EY, Chang WC, Zha Z, Lim SO, Lai YJ, Liu C, Liu J, Dong Q, Yang Y, Sun L, Wei Y, Nie L, Hsu JL, Li H, Ye Q, Hassan MM, Amin HM, Kaseb AO, Lin X, Wang SC, Hung MC. IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion. J Clin Invest. 2019 07 15; 129(8):3324-3338. PMID: 31305264.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    27. Lin P, He W, Nie L, Schauer JJ, Wang Y, Yang S, Zhang Y. Comparison of PM2.5 emission rates and source profiles for traditional Chinese cooking styles. Environ Sci Pollut Res Int. 2019 Jul; 26(21):21239-21252. PMID: 31115821.
      Citations:    Fields:    Translation:PHPublic Health
    28. Han Y, Chen MK, Wang HL, Hsu JL, Li CW, Chu YY, Liu CX, Nie L, Chan LC, Yam C, Wang SC, He GJ, Hortobagyi GN, Tan XD, Hung MC. Synergism of PARP inhibitor fluzoparib (HS10160) and MET inhibitor HS10241 in breast and ovarian cancer cells. Am J Cancer Res. 2019; 9(3):608-618. PMID: 30949414.
      Citations: 12     
    29. Lee PC, Fang YF, Yamaguchi H, Wang WJ, Chen TC, Hong X, Ke B, Xia W, Wei Y, Zha Z, Wang Y, Kuo HP, Wang CW, Tu CY, Chen CH, Huang WC, Chiang SF, Nie L, Hou J, Chen CT, Huo L, Yang WH, Deng R, Nakai K, Hsu YH, Chang SS, Chiu TJ, Tang J, Zhang R, Wang L, Fang B, Chen T, Wong KK, Hsu JL, Hung MC. Targeting PKCd as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer. Cancer Cell. 2018 12 10; 34(6):954-969.e4. PMID: 30537515.
      Citations: 25     Fields:    Translation:HumansCells
    30. Zhou H, Yuan Y, Nie L. Accuracy, Safety, and Reliability of Novel Phase I Designs-Response. Clin Cancer Res. 2018 11 01; 24(21):5483-5484. PMID: 30385656.
      Citations: 3     Fields:    
    31. Wang H, Nie L, Xu Y, Du C, Zhang T, Wang Y. Effects of Highway-Related Pollutant on the Groundwater Quality of Turfy Swamps in the Changbai Mountain Area. Int J Environ Res Public Health. 2018 08 03; 15(8). PMID: 30081526.
      Citations:    Fields:    Translation:CellsPHPublic Health
    32. Yuan Y, Lin R, Li D, Nie L, Warren KE. Time-to-Event Bayesian Optimal Interval Design to Accelerate Phase I Trials. Clin Cancer Res. 2018 10 15; 24(20):4921-4930. PMID: 29769209.
      Citations: 17     Fields:    Translation:Humans
    33. Xue Y, Cheng L, Chen X, Zhai X, Wang W, Zhang W, Bai Y, Tian H, Nie L, Zhang S, Wei T. Emission characteristics of harmful air pollutants from cremators in Beijing, China. PLoS One. 2018; 13(5):e0194226. PMID: 29718907.
      Citations: 2     Fields:    Translation:PHPublic Health
    34. Wang H, Nie L, Xu Y, Li M, Lv Y. Traffic-emitted metal status and uptake by Carex meyeriana Kunth and Thelypteris palustris var. pubescens Fernald growing in roadside turfy swamp in the Changbai Mountain area, China. Environ Sci Pollut Res Int. 2018 Jul; 25(19):18498-18509. PMID: 29696547.
      Citations: 2     Fields:    Translation:AnimalsPHPublic Health
    35. Zhou H, Yuan Y, Nie L. Accuracy, Safety, and Reliability of Novel Phase I Trial Designs. Clin Cancer Res. 2018 09 15; 24(18):4357-4364. PMID: 29661774.
      Citations: 23     Fields:    Translation:Humans
    36. Jen EY, Ko CW, Lee JE, Del Valle PL, Aydanian A, Jewell C, Norsworthy KJ, Przepiorka D, Nie L, Liu J, Sheth CM, Shapiro M, Farrell AT, Pazdur R. FDA Approval: Gemtuzumab Ozogamicin for the Treatment of Adults with Newly Diagnosed CD33-Positive Acute Myeloid Leukemia. Clin Cancer Res. 2018 07 15; 24(14):3242-3246. PMID: 29476018.
      Citations: 54     Fields:    Translation:Humans
    37. Zhang J, Ko CW, Nie L, Chen Y, Tiwari R. Bayesian hierarchical methods for meta-analysis combining randomized-controlled and single-arm studies. Stat Methods Med Res. 2019 05; 28(5):1293-1310. PMID: 29433407.
      Citations: 3     Fields:    Translation:Humans
    38. Xu M, He WQ, Nie L, Han LH, Pan T, Shi AJ. [Atmospheric Pollutant Emission Characteristics from the Cooking Process of Traditional Beijing Roast Duck]. Huan Jing Ke Xue. 2017 Aug 08; 38(8):3139-3145. PMID: 29964919.
      Citations:    Fields:    Translation:AnimalsPHPublic Health
    39. Zhang F, Xiang S, Cao Y, Li M, Ma Q, Liang H, Li H, Ye Y, Zhang Y, Jiang L, Hu Y, Zhou J, Wang X, Zhang Y, Nie L, Liang X, Gong W, Liu Y. EIF3D promotes gallbladder cancer development by stabilizing GRK2 kinase and activating PI3K-AKT signaling pathway. Cell Death Dis. 2017 06 08; 8(6):e2868. PMID: 28594409.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    40. Gormley NJ, Ko CW, Deisseroth A, Nie L, Kaminskas E, Kormanik N, Goldberg KB, Farrell AT, Pazdur R. FDA Drug Approval: Elotuzumab in Combination with Lenalidomide and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma. Clin Cancer Res. 2017 Nov 15; 23(22):6759-6763. PMID: 28249893.
      Citations: 7     Fields:    Translation:Humans
    41. Zhao LL, Zhang F, Chen P, Xie XL, Dou YQ, Lin YL, Nie L, Lv P, Zhang DD, Li XK, Miao SB, Yin YJ, Dong LH, Song Y, Shu YN, Han M. Insulin-independent GLUT4 translocation in proliferative vascular smooth muscle cells involves SM22a. J Mol Med (Berl). 2017 02; 95(2):181-192. PMID: 27631639.
      Citations: 2     Fields:    Translation:AnimalsCells
    42. Ko HW, Lee HH, Huo L, Xia W, Yang CC, Hsu JL, Li LY, Lai CC, Chan LC, Cheng CC, Labaff AM, Liao HW, Lim SO, Li CW, Wei Y, Nie L, Yamaguchi H, Hung MC. GSK3ß inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers. Oncotarget. 2016 Aug 30; 7(35):57131-57144. PMID: 27494834.
      Citations: 19     Fields:    Translation:HumansCells
    43. Nie L, Rubin EH, Mehrotra N, Pinheiro J, Fernandes LL, Roy A, Bailey S, de Alwis DP. Rendering the 3 + 3 Design to Rest: More Efficient Approaches to Oncology Dose-Finding Trials in the Era of Targeted Therapy. Clin Cancer Res. 2016 06 01; 22(11):2623-9. PMID: 27250933.
      Citations: 23     Fields:    Translation:HumansAnimals
    44. Li X, Jung JJ, Nie L, Razavian M, Zhang J, Samuel V, Sadeghi MM. The neuropilin-like protein ESDN regulates insulin signaling and sensitivity. Am J Physiol Heart Circ Physiol. 2016 05 01; 310(9):H1184-93. PMID: 26921437.
      Citations: 11     Fields:    Translation:AnimalsCells
    45. Rahal OM, Nie L, Chan LC, Li CW, Hsu YH, Hsu J, Yu D, Hung MC. Selective expression of constitutively active pro-apoptotic protein BikDD gene in primary mammary tumors inhibits tumor growth and reduces tumor initiating cells. Am J Cancer Res. 2015; 5(12):3624-34. PMID: 26885451.
      Citations: 1     
    46. Li W, Xiao J, Zhou X, Xu M, Hu C, Xu X, Lu Y, Liu C, Xue S, Nie L, Zhang H, Li Z, Zhang Y, Ji F, Hui L, Tao W, Wei B, Wang H. STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma. J Clin Invest. 2015 Nov 02; 125(11):4239-54. PMID: 26457732.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    47. de Claro RA, McGinn KM, Verdun N, Lee SL, Chiu HJ, Saber H, Brower ME, Chang CJ, Pfuma E, Habtemariam B, Bullock J, Wang Y, Nie L, Chen XH, Lu DR, Al-Hakim A, Kane RC, Kaminskas E, Justice R, Farrell AT, Pazdur R. FDA Approval: Ibrutinib for Patients with Previously Treated Mantle Cell Lymphoma and Previously Treated Chronic Lymphocytic Leukemia. Clin Cancer Res. 2015 Aug 15; 21(16):3586-90. PMID: 26275952.
      Citations: 33     Fields:    Translation:Humans
    48. Yang CC, LaBaff A, Wei Y, Nie L, Xia W, Huo L, Yamaguchi H, Hsu YH, Hsu JL, Liu D, Lang J, Du Y, Lien HC, Li LY, Deng R, Chan LC, Yao J, Kleer CG, Hortobagyi GN, Hung MC. Phosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancers. Am J Transl Res. 2015; 7(6):1009-20. PMID: 26279746.
      Citations: 23     
    49. Liu YQ, Zhang Q, Da R, Luo YL, Su Y, Wu ZW, Yan CL, Nie L. [Effect of ultrafiltration-membrane extracts of Radix Rehmanniae Praeparata on proliferation and genetic stability of bone marrow-derived mesenchymal stem cells induced by cadmium chloride]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2015 Apr; 35(4):450-6. PMID: 26043569.
      Citations:    Fields:    Translation:HumansCells
    50. Miller BW, Przepiorka D, de Claro RA, Lee K, Nie L, Simpson N, Gudi R, Saber H, Shord S, Bullock J, Marathe D, Mehrotra N, Hsieh LS, Ghosh D, Brown J, Kane RC, Justice R, Kaminskas E, Farrell AT, Pazdur R. FDA approval: idelalisib monotherapy for the treatment of patients with follicular lymphoma and small lymphocytic lymphoma. Clin Cancer Res. 2015 Apr 01; 21(7):1525-9. PMID: 25645861.
      Citations: 57     Fields:    Translation:Humans
    51. Deisseroth A, Ko CW, Nie L, Zirkelbach JF, Zhao L, Bullock J, Mehrotra N, Del Valle P, Saber H, Sheth C, Gehrke B, Justice R, Farrell A, Pazdur R. FDA approval: siltuximab for the treatment of patients with multicentric Castleman disease. Clin Cancer Res. 2015 Mar 01; 21(5):950-4. PMID: 25601959.
      Citations: 42     Fields:    Translation:HumansAnimals
    52. Chen Y, Liu Y, Ning J, Nie L, Zhu H, Chu H. A composite likelihood method for bivariate meta-analysis in diagnostic systematic reviews. Stat Methods Med Res. 2017 04; 26(2):914-930. PMID: 25512146.
      Citations: 4     Fields:    Translation:Humans
    53. Huo L, Li CW, Huang TH, Lam YC, Xia W, Tu C, Chang WC, Hsu JL, Lee DF, Nie L, Yamaguchi H, Wang Y, Lang J, Li LY, Chen CH, Mishra L, Hung MC. Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells. Am J Transl Res. 2014; 6(6):649-63. PMID: 25628777.
      Citations: 14     
    54. Hu T, Yang HL, Tang Q, Zhang H, Nie L, Li L, Wang JF, Liu DM, Jiang W, Wang F, Zang HC. Absolutely nondestructive discrimination of Huoshan Dendrobium nobile species with miniature near-infrared (NIR) spectrometer engine. Guang Pu Xue Yu Guang Pu Fen Xi. 2014 Oct; 34(10):2808-14. PMID: 25739230.
      Citations:    Fields:    Translation:Animals
    55. Wang P, Zhang H, Yang H, Nie L, Zang H. Rapid determination of major bioactive isoflavonoid compounds during the extraction process of kudzu (Pueraria lobata) by near-infrared transmission spectroscopy. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 25; 137:1403-8. PMID: 25310261.
      Citations: 10     Fields:    Translation:Animals
    56. Song L, Wang S, Duan X, Liu X, Li Z, Nie L, Chu G. Chromatographic fingerprint combined with content of asperosaponin VI and antioxidant activity for quality evaluation of wine-fried Dipsaci Radix. Nat Prod Commun. 2014 Jun; 9(6):773-8. PMID: 25115076.
      Citations: 1     Fields:    Translation:Animals
    57. Lee HZ, Miller BW, Kwitkowski VE, Ricci S, DelValle P, Saber H, Grillo J, Bullock J, Florian J, Mehrotra N, Ko CW, Nie L, Shapiro M, Tolnay M, Kane RC, Kaminskas E, Justice R, Farrell AT, Pazdur R. U.S. Food and drug administration approval: obinutuzumab in combination with chlorambucil for the treatment of previously untreated chronic lymphocytic leukemia. Clin Cancer Res. 2014 Aug 01; 20(15):3902-7. PMID: 24824310.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    58. Nie L, Guo X, Esmailzadeh L, Zhang J, Asadi A, Collinge M, Li X, Kim JD, Woolls M, Jin SW, Dubrac A, Eichmann A, Simons M, Bender JR, Sadeghi MM. Transmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenesis. J Clin Invest. 2013 Dec; 123(12):5082-97. PMID: 24177422.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    59. Nie L, Chen D, Suo J, Zou P, Feng S, Yang Q, Yang S, Ye S. Physicochemical characterization and biocompatibility in vitro of biphasic calcium phosphate/polyvinyl alcohol scaffolds prepared by freeze-drying method for bone tissue engineering applications. Colloids Surf B Biointerfaces. 2012 Dec 01; 100:169-76. PMID: 22766294.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    60. Nie L, Wu HJ, Hsu JM, Chang SS, Labaff AM, Li CW, Wang Y, Hsu JL, Hung MC. Long non-coding RNAs: versatile master regulators of gene expression and crucial players in cancer. Am J Transl Res. 2012; 4(2):127-50. PMID: 22611467.
      Citations: 110     
    61. Chen Y, Chu H, Luo S, Nie L, Chen S. Bayesian analysis on meta-analysis of case-control studies accounting for within-study correlation. Stat Methods Med Res. 2015 Dec; 24(6):836-55. PMID: 22143403.
      Citations: 8     Fields:    Translation:Humans
    62. Wang Y, Luo Z, Shi X, Wang H, Nie L, Huang M. A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin. Protein Sci. 2011 Dec; 20(12):2095-101. PMID: 21997768.
      Citations: 5     Fields:    Translation:HumansCells
    63. Esplin BL, Shimazu T, Welner RS, Garrett KP, Nie L, Zhang Q, Humphrey MB, Yang Q, Borghesi LA, Kincade PW. Chronic exposure to a TLR ligand injures hematopoietic stem cells. J Immunol. 2011 May 01; 186(9):5367-75. PMID: 21441445.
      Citations: 152     Fields:    Translation:AnimalsCells
    64. Nie L, Zhao Y, Wu W, Yang YZ, Wang HC, Sun XH. Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes. Cell Res. 2011 May; 21(5):754-69. PMID: 21119685.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    65. Wang LM, Chi YJ, Wang LN, Nie L, Zou YH, Zhao TN, Li CY, Chen M, Huo MX. [Expression of interleukin-6 in rat model of doxorubicin-induced nephropathy]. Zhongguo Dang Dai Er Ke Za Zhi. 2010 Nov; 12(11):912-4. PMID: 21083990.
      Citations: 7     Fields:    Translation:Animals
    66. Nie L, Chu H, Feng S. Estimating variance parameters from multivariate normal variables subject to limit of detection: MLE, REML, or Bayesian approaches? Stat Med. 2009 Sep 10; 28(20):2605-16. PMID: 19598183.
      Citations: 1     Fields:    Translation:Animals
    67. Guo X, Nie L, Esmailzadeh L, Zhang J, Bender JR, Sadeghi MM. Endothelial and smooth muscle-derived neuropilin-like protein regulates platelet-derived growth factor signaling in human vascular smooth muscle cells by modulating receptor ubiquitination. J Biol Chem. 2009 Oct 23; 284(43):29376-82. PMID: 19696027.
      Citations: 14     Fields:    Translation:HumansCells
    68. Wang HY, Zhu XF, Wang LM, Luo ZH, Yang ZJ, Liu DY, Yuan DX, Nie L, Wu YJ, Wang SX. [Brain-derived neurotrophic factor and neural stem cells transplantation in treatment of hypoxic-ischemic brain injury in rats]. Zhonghua Er Ke Za Zhi. 2008 Jul; 46(7):544-9. PMID: 19099818.
      Citations: 2     Fields:    Translation:AnimalsCells
    69. Chen J, Zhong J, Nie L. Bayesian hierarchical modeling of drug stability data. Stat Med. 2008 Jun 15; 27(13):2361-80. PMID: 18338325.
      Citations:    Fields:    
    70. Chu H, Nie L, Kensler TW. A Bayesian approach estimating treatment effects on biomarkers containing zeros with detection limits. Stat Med. 2008 Jun 15; 27(13):2497-508. PMID: 18167630.
      Citations: 3     Fields:    Translation:Humans
    71. Nie L, Perry SS, Zhao Y, Huang J, Kincade PW, Farrar MA, Sun XH. Regulation of lymphocyte development by cell-type-specific interpretation of Notch signals. Mol Cell Biol. 2008 Mar; 28(6):2078-90. PMID: 18195039.
      Citations: 19     Fields:    Translation:AnimalsCells
    72. Nie L, Wu H, Sun XH. Ubiquitination and degradation of Tal1/SCL are induced by notch signaling and depend on Skp2 and CHIP. J Biol Chem. 2008 Jan 11; 283(2):684-92. PMID: 17962192.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    73. Perry SS, Zhao Y, Nie L, Cochrane SW, Huang Z, Sun XH. Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenance. Blood. 2007 Oct 01; 110(7):2351-60. PMID: 17622570.
      Citations: 55     Fields:    Translation:AnimalsCells
    74. Nie L, Zhang QX, Han ZX, Shao YH, Rong JG, Liu SW, Kong XG. [Genetic variations of membrane gene of infectious bronchitis virus strains isolated in China between 1995 and 2004]. Bing Du Xue Bao. 2007 Jul; 23(4):298-304. PMID: 17894233.
      Citations:    Fields:    Translation:Cells
    75. Nie L, Chu H, Cole SR. A general approach for sample size and statistical power calculations assessing of interventions using a mixture model in the presence of detection limits. Contemp Clin Trials. 2006 Oct; 27(5):483-91. PMID: 16769254.
      Citations: 1     Fields:    Translation:Humans
    76. Zhang Z, Niu Z, Yuan W, Liu W, Xiang L, Zhang J, Chu X, Zhao J, Jiang F, Chai B, Cui F, Wang Y, Zhang K, Wang Y, Xu S, Xia L, Gu J, Zhang S, Meng X, Wang S, Gao S, Fan M, Nie L, Zheng Z, Huang W. Fine mapping and identification of a candidate gene SSH1 in disseminated superficial actinic porokeratosis. Hum Mutat. 2004 Nov; 24(5):438. PMID: 15459975.
      Citations: 9     Fields:    Translation:HumansCells
    77. Huang Z, Nie L, Xu M, Sun XH. Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination. Mol Cell Biol. 2004 Oct; 24(20):8951-62. PMID: 15456869.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    78. Nie L, Xu M, Vladimirova A, Sun XH. Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities. EMBO J. 2003 Nov 03; 22(21):5780-92. PMID: 14592976.
      Citations: 66     Fields:    Translation:AnimalsCells
    79. Xu M, Nie L, Kim SH, Sun XH. STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbeta. EMBO J. 2003 Feb 17; 22(4):893-904. PMID: 12574125.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    80. Kim D, Xu M, Nie L, Peng XC, Jimi E, Voll RE, Nguyen T, Ghosh S, Sun XH. Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kappaB activities. Immunity. 2002 Jan; 16(1):9-21. PMID: 11825562.
      Citations: 21     Fields:    Translation:AnimalsCells
    81. Activation of keap1/nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells. American Journal of Translational Research. 6:649-663.
    82. GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers. Oncotarget. 7:57131-57144.
    83. Selective expression of constitutively active pro-apoptotic protein BikDD gene in primary mammary tumors inhibits tumor growth and reduces tumor initiating cells. American Journal of Cancer Research. 5:3624-3634.
    84. Phosphorylation of ezh2 at t416 by cdk2 contributes to the malignancy of triple negative breast cancers. American Journal of Translational Research. 7:1009-1020.
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