TitleAssociate Professor
InstitutionMD Anderson
DepartmentStem Cell Transplantation
Address7435 Fannin St
Houston TX 77054-1901
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Montalban-Bravo G, Ma F, Thongon N, Yang H, Gomez IG, Rodriguez-Sevilla JJ, Adema V, Wildeman B, Lockyer P, Kim YJ, Tanaka T, Darbaniyan F, Pancholy S, Zhang G, Al-Atrash G, Dwyer K, Takahashi K, Garcia-Manero G, Kantarjian H, Colla S. Targeting MCL1-driven anti-apoptotic pathways to overcome hypomethylating agent resistance in RAS -mutated chronic myelomonocytic leukemia. bioRxiv. 2023 Apr 08. PMID: 37066354; PMCID: PMC10104149.
    2. Sokol L, Tsianakas A, Musiek A, Ortiz-Romero PL, Poligone B, Duvic M, Elmets C, Leoni M, Dwyer K, Ito T, Herr F, Kim YH, Bagot M, Dalle S. Long-term disease control and safety with the anti-CCR4 antibody mogamulizumab: Post-hoc analyses from the MAVORIC trial of patients with previously treated cutaneous T-cell lymphoma. Dermatol Ther. 2022 08; 35(8):e15634. PMID: 35695215; PMCID: PMC9539986.
      Citations:    Fields:    
    3. Thongon N, Ma F, Santoni A, Marchesini M, Fiorini E, Rose A, Adema V, Ganan-Gomez I, Groarke EM, Gutierrez-Rodrigues F, Chen S, Lockyer P, Schneider S, Bueso-Ramos C, Montalban-Bravo G, Class CA, Soltysiak KA, Pellegrini M, Sahin E, Bertuch AA, DiNardo CD, Garcia-Manero G, Young NS, Dwyer K, Colla S. Hematopoiesis under telomere attrition at the single-cell resolution. Nat Commun. 2021 11 25; 12(1):6850. PMID: 34824242; PMCID: PMC8617077.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    4. Horwitz S, Kim YH, Moskowitz AJ, Porcu P, Dwyer K, Sun W, Herr FM, Scarisbrick J, Zinzani PL, Bagot M. Lack of impact of type and extent of prior therapy on outcomes of mogamulizumab therapy in patients with cutaneous T cell lymphoma in the MAVORIC trial. Leuk Lymphoma. 2021 12; 62(13):3109-3118. PMID: 34304674; PMCID: PMC9447791.
      Citations: 1     Fields:    Translation:Humans
    5. Bongoni AK, Lu B, Salvaris EJ, Roberts V, Fang D, McRae JL, Fisicaro N, Dwyer KM, Cowan PJ. Overexpression of Human CD55 and CD59 or Treatment with Human CD55 Protects against Renal Ischemia-Reperfusion Injury in Mice. J Immunol. 2017 06 15; 198(12):4837-4845. PMID: 28500075.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    6. Covarrubias R, Chepurko E, Reynolds A, Huttinger ZM, Huttinger R, Stanfill K, Wheeler DG, Novitskaya T, Robson SC, Dwyer KM, Cowan PJ, Gumina RJ. Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice. Arterioscler Thromb Vasc Biol. 2016 09; 36(9):1809-20. PMID: 27417582; PMCID: PMC5206760.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    7. Zinzani PL, Radford J, Caballero D, Fields P, Chamuleau ME, d'Amore F, Johnson PW, van Imhoff GW, Ng T, Dwyer K, Karlin L, Haioun C, Thieblemont C, Gonz?lez-Barca E, Garc?a CG, Morschhauser F. European phase II study of mogamulizumab, an anti-CCR4 monoclonal antibody, in relapsed/refractory peripheral T-cell lymphoma. Haematologica. 2016 10; 101(10):e407-e410. PMID: 27418646; PMCID: PMC5046662.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    8. Colla S, Ong DS, Ogoti Y, Marchesini M, Mistry NA, Clise-Dwyer K, Ang SA, Storti P, Viale A, Giuliani N, Ruisaard K, Ganan Gomez I, Bristow CA, Estecio M, Weksberg DC, Ho YW, Hu B, Genovese G, Pettazzoni P, Multani AS, Jiang S, Hua S, Ryan MC, Carugo A, Nezi L, Wei Y, Yang H, D'Anca M, Zhang L, Gaddis S, Gong T, Horner JW, Heffernan TP, Jones P, Cooper LJ, Liang H, Kantarjian H, Wang YA, Chin L, Bueso-Ramos C, Garcia-Manero G, DePinho RA. Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndrome. Cancer Cell. 2015 May 11; 27(5):644-57. PMID: 25965571; PMCID: PMC4596059.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    9. Mallampati S, Leng X, Ma H, Zeng J, Li J, Wang H, Lin K, Lu Y, Yang Y, Sun B, Gong Y, Lee JS, Konopleva M, Andreeff M, Arlinghaus RB, Cai Z, Fang B, Shen H, Han X, Hirsch-Ginsberg CF, Gao X, Paranjape AN, Mani SA, Clise-Dwyer K, Sun X. Tyrosine kinase inhibitors induce mesenchymal stem cell-mediated resistance in BCR-ABL+ acute lymphoblastic leukemia. Blood. 2015 May 07; 125(19):2968-73. PMID: 25712988; PMCID: PMC4424418.
      Citations: 13     Fields:    Translation:AnimalsCells
    10. Duvic M, Pinter-Brown LC, Foss FM, Sokol L, Jorgensen JL, Challagundla P, Dwyer KM, Zhang X, Kurman MR, Ballerini R, Liu L, Kim YH. Phase 1/2 study of mogamulizumab, a defucosylated anti-CCR4 antibody, in previously treated patients with cutaneous T-cell lymphoma. Blood. 2015 Mar 19; 125(12):1883-9. PMID: 25605368; PMCID: PMC4375715.
      Citations: 61     Fields:    Translation:HumansCTClinical Trials
    11. Li J, Kurasawa Y, Wang Y, Clise-Dwyer K, Klumpp SA, Liang H, Tailor RC, Raymond AC, Estrov Z, Brandt SJ, Davis RE, Zweidler-McKay P, Amin HM, Nagarajan L. Requirement for ssbp2 in hematopoietic stem cell maintenance and stress response. J Immunol. 2014 Nov 01; 193(9):4654-62. PMID: 25238756; PMCID: PMC4201964.
      Citations: 8     Fields:    Translation:AnimalsCells
    12. Jiang H, Clise-Dwyer K, Ruisaard KE, Fan X, Tian W, Gumin J, Lamfers ML, Kleijn A, Lang FF, Yung WK, Vence LM, Gomez-Manzano C, Fueyo J. Delta-24-RGD oncolytic adenovirus elicits anti-glioma immunity in an immunocompetent mouse model. PLoS One. 2014; 9(5):e97407. PMID: 24827739; PMCID: PMC4020829.
      Citations: 59     Fields:    Translation:AnimalsCells
    13. Beavis PA, Divisekera U, Paget C, Chow MT, John LB, Devaud C, Dwyer K, Stagg J, Smyth MJ, Darcy PK. Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors. Proc Natl Acad Sci U S A. 2013 Sep 03; 110(36):14711-6. PMID: 23964122; PMCID: PMC3767556.
      Citations: 134     Fields:    Translation:HumansAnimalsCells
    14. McFarlin BK, Williams RR, Venable AS, Dwyer KC, Haviland DL. Image-based cytometry reveals three distinct subsets of activated granulocytes based on phagocytosis and oxidative burst. Cytometry A. 2013 Aug; 83(8):745-51. PMID: 23839911.
      Citations: 9     Fields:    Translation:HumansCells
    15. Pommey S, Lu B, McRae J, Stagg J, Hill P, Salvaris E, Robson SC, d'Apice AJ, Cowan PJ, Dwyer KM. Liver grafts from CD39-overexpressing rodents are protected from ischemia reperfusion injury due to reduced numbers of resident CD4+ T cells. Hepatology. 2013 Apr; 57(4):1597-606. PMID: 22829222.
      Citations: 24     Fields:    Translation:AnimalsCells
    16. Zhang M, Sukhumalchandra P, Enyenihi AA, St John LS, Hunsucker SA, Mittendorf EA, Sergeeva A, Ruisaard K, Al-Atrache Z, Ropp PA, Jakher H, Rodriguez-Cruz T, Lizee G, Clise-Dwyer K, Lu S, Molldrem JJ, Glish GL, Armistead PM, Alatrash G. A novel HLA-A*0201 restricted peptide derived from cathepsin G is an effective immunotherapeutic target in acute myeloid leukemia. Clin Cancer Res. 2013 Jan 01; 19(1):247-57. PMID: 23147993; PMCID: PMC3537920.
      Citations: 14     Fields:    Translation:HumansCells
    17. Alatrash G, Mittendorf EA, Sergeeva A, Sukhumalchandra P, Qiao N, Zhang M, St John LS, Ruisaard K, Haugen CE, Al-Atrache Z, Jakher H, Philips AV, Ding X, Chen JQ, Wu Y, Patenia RS, Bernatchez C, Vence LM, Radvanyi LG, Hwu P, Clise-Dwyer K, Ma Q, Lu S, Molldrem JJ. Broad cross-presentation of the hematopoietically derived PR1 antigen on solid tumors leads to susceptibility to PR1-targeted immunotherapy. J Immunol. 2012 Dec 01; 189(11):5476-84. PMID: 23105141; PMCID: PMC3504175.
      Citations: 18     Fields:    Translation:HumansCells
    18. Wang YM, McRae JL, Robson SC, Cowan PJ, Zhang GY, Hu M, Polhill T, Wang Y, Zheng G, Wang Y, Lee VW, Unwin RJ, Harris DC, Dwyer KM, Alexander SI. Regulatory T cells participate in CD39-mediated protection from renal injury. Eur J Immunol. 2012 Sep; 42(9):2441-51. PMID: 22684996.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    19. Huttinger ZM, Milks MW, Nickoli MS, Aurand WL, Long LC, Wheeler DG, Dwyer KM, d'Apice AJ, Robson SC, Cowan PJ, Gumina RJ. Ectonucleotide triphosphate diphosphohydrolase-1 (CD39) mediates resistance to occlusive arterial thrombus formation after vascular injury in mice. Am J Pathol. 2012 Jul; 181(1):322-33. PMID: 22613024; PMCID: PMC3388153.
      Citations: 11     Fields:    Translation:AnimalsCells
    20. Mittendorf EA, Alatrash G, Qiao N, Wu Y, Sukhumalchandra P, St John LS, Philips AV, Xiao H, Zhang M, Ruisaard K, Clise-Dwyer K, Lu S, Molldrem JJ. Breast cancer cell uptake of the inflammatory mediator neutrophil elastase triggers an anticancer adaptive immune response. Cancer Res. 2012 Jul 01; 72(13):3153-62. PMID: 22564522; PMCID: PMC3397251.
      Citations: 44     Fields:    Translation:HumansCells
    21. Alatrash G, Ono Y, Sergeeva A, Sukhumalchandra P, Zhang M, St John LS, Yang TH, Ruisaard K, Armistead PM, Mittendorf EA, He H, Qiao N, Rodriguez-Cruz T, Liang S, Clise-Dwyer K, Wieder ED, Lizee G, Lu S, Molldrem JJ. The role of antigen cross-presentation from leukemia blasts on immunity to the leukemia-associated antigen PR1. J Immunother. 2012 May; 35(4):309-20. PMID: 22495388; PMCID: PMC3326226.
      Citations: 16     Fields:    Translation:HumansCells
    22. Cai M, Huttinger ZM, He H, Zhang W, Li F, Goodman LA, Wheeler DG, Druhan LJ, Zweier JL, Dwyer KM, He G, d'Apice AJ, Robson SC, Cowan PJ, Gumina RJ. Transgenic over expression of ectonucleotide triphosphate diphosphohydrolase-1 protects against murine myocardial ischemic injury. J Mol Cell Cardiol. 2011 Dec; 51(6):927-35. PMID: 21939667; PMCID: PMC3245748.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    23. Sergeeva A, Alatrash G, He H, Ruisaard K, Lu S, Wygant J, McIntyre BW, Ma Q, Li D, St John L, Clise-Dwyer K, Molldrem JJ. An anti-PR1/HLA-A2 T-cell receptor-like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells. Blood. 2011 Apr 21; 117(16):4262-72. PMID: 21296998; PMCID: PMC3087478.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    24. Ma Q, Wang C, Jones D, Quintanilla KE, Li D, Wang Y, Wieder ED, Clise-Dwyer K, Alatrash G, Mj Y, Munsell MF, Lu S, Qazilbash MH, Molldrem JJ. Adoptive transfer of PR1 cytotoxic T lymphocytes associated with reduced leukemia burden in a mouse acute myeloid leukemia xenograft model. Cytotherapy. 2010 Dec; 12(8):1056-62. PMID: 20735170; PMCID: PMC3365857.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    25. Kanodia S, Wieder E, Lu S, Talpaz M, Alatrash G, Clise-Dwyer K, Molldrem JJ. PR1-specific T cells are associated with unmaintained cytogenetic remission of chronic myelogenous leukemia after interferon withdrawal. PLoS One. 2010 Jul 26; 5(7):e11770. PMID: 20668669; PMCID: PMC2909896.
      Citations: 14     Fields:    Translation:HumansCells
    26. Samudio IJ, Duvvuri S, Clise-Dwyer K, Watt JC, Mak D, Kantarjian H, Yang D, Ruvolo V, Borthakur G. Activation of p53 signaling by MI-63 induces apoptosis in acute myeloid leukemia cells. Leuk Lymphoma. 2010 May; 51(5):911-919. PMID: 20423286; PMCID: PMC4122268.
      Citations: 7     Fields:    Translation:HumansCells
    27. Ling X, Marini F, Konopleva M, Schober W, Shi Y, Burks J, Clise-Dwyer K, Wang RY, Zhang W, Yuan X, Lu H, Caldwell L, Andreeff M. Mesenchymal Stem Cells Overexpressing IFN-? Inhibit Breast Cancer Growth and Metastases through Stat3 Signaling in a Syngeneic Tumor Model. Cancer Microenviron. 2010 Mar 19; 3(1):83-95. PMID: 21209776; PMCID: PMC2990497.
      Citations: 42     
    28. Stagg J, Divisekera U, McLaughlin N, Sharkey J, Pommey S, Denoyer D, Dwyer KM, Smyth MJ. Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis. Proc Natl Acad Sci U S A. 2010 Jan 26; 107(4):1547-52. PMID: 20080644; PMCID: PMC2824381.
      Citations: 250     Fields:    Translation:AnimalsCells
    29. Tsukamoto H, Clise-Dwyer K, Huston GE, Duso DK, Buck AL, Johnson LL, Haynes L, Swain SL. Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects. Proc Natl Acad Sci U S A. 2009 Oct 27; 106(43):18333-8. PMID: 19815516; PMCID: PMC2759371.
      Citations: 76     Fields:    Translation:AnimalsCells
    30. Fiegl M, Samudio I, Clise-Dwyer K, Burks JK, Mnjoyan Z, Andreeff M. CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure. Blood. 2009 Feb 12; 113(7):1504-12. PMID: 18957686; PMCID: PMC2644078.
      Citations: 60     Fields:    Translation:HumansCells
    31. Samudio I, Fiegl M, McQueen T, Clise-Dwyer K, Andreeff M. The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation. Cancer Res. 2008 Jul 01; 68(13):5198-205. PMID: 18593920; PMCID: PMC2562568.
      Citations: 72     Fields:    Translation:HumansCells
    32. Jones SC, Clise-Dwyer K, Huston G, Dibble J, Eaton S, Haynes L, Swain SL. Impact of post-thymic cellular longevity on the development of age-associated CD4+ T cell defects. J Immunol. 2008 Apr 01; 180(7):4465-75. PMID: 18354168; PMCID: PMC2366213.
      Citations: 19     Fields:    Translation:AnimalsCells
    33. Clise-Dwyer K, Huston GE, Buck AL, Duso DK, Swain SL. Environmental and intrinsic factors lead to antigen unresponsiveness in CD4(+) recent thymic emigrants from aged mice. J Immunol. 2007 Feb 01; 178(3):1321-31. PMID: 17237378.
      Citations: 40     Fields:    Translation:AnimalsCells
    34. Swain S, Clise-Dwyer K, Haynes L. Homeostasis and the age-associated defect of CD4 T cells. Semin Immunol. 2005 Oct; 17(5):370-7. PMID: 15964201; PMCID: PMC3030243.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    35. Dwyer KM, Robson SC, Nandurkar HH, Campbell DJ, Gock H, Murray-Segal LJ, Fisicaro N, Mysore TB, Kaczmarek E, Cowan PJ, d'Apice AJ. Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation. J Clin Invest. 2004 May; 113(10):1440-6. PMID: 15146241; PMCID: PMC406523.
      Citations: 86     Fields:    Translation:HumansAnimalsCells
    36. Clise-Dwyer K, Amanna IJ, Duzeski JL, Nashold FE, Hayes CE. Genetic studies of B-lymphocyte deficiency and mastocytosis in strain A/WySnJ mice. Immunogenetics. 2001 Dec; 53(9):729-35. PMID: 11862404.
      Citations: 4     Fields:    Translation:AnimalsCells
    37. Harless SM, Lentz VM, Sah AP, Hsu BL, Clise-Dwyer K, Hilbert DM, Hayes CE, Cancro MP. Competition for BLyS-mediated signaling through Bcmd/BR3 regulates peripheral B lymphocyte numbers. Curr Biol. 2001 Dec 11; 11(24):1986-9. PMID: 11747827.
      Citations: 56     Fields:    Translation:AnimalsCells
    38. Amanna IJ, Clise-Dwyer K, Nashold FE, Hoag KA, Hayes CE. Cutting edge: A/WySnJ transitional B cells overexpress the chromosome 15 proapoptotic Blk gene and succumb to premature apoptosis. J Immunol. 2001 Dec 01; 167(11):6069-72. PMID: 11714762.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    39. Hoag KA, Clise-Dwyer K, Lim YH, Nashold FE, Gestwicki J, Cancro MP, Hayes CE. A quantitative-trait locus controlling peripheral B-cell deficiency maps to mouse Chromosome 15. Immunogenetics. 2000 Sep; 51(11):924-9. PMID: 11003386.
      Citations: 8     Fields:    Translation:AnimalsCells
    40. Neutrophil elastase enhances antigen presentation by upregulating human leukocyte antigen class I expression on tumor cells. Cancer Immunology, Immunotherapy. 1-11.
    41. A novel TCR-like CAR with specificity for PR1/HLA-A2 effectively targets myeloid leukemia in vitro when expressed in human adult peripheral blood and cord blood T cells. Cytotherapy.
    42. PR1 peptide vaccine induces specific immunity with clinical responses in myeloid malignancies. Leukemia.
    43. Activity of 8F4, a T-cell receptor-like anti-PR1/HLA-A2 antibody, against primary human AML in vivo. Leukemia.
    44. Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma. OncoImmunology. 5.
    45. PR1-specific cytotoxic T lymphocytes are relatively frequent in umbilical cord blood and can be effectively expanded to target myeloid leukemia. Cytotherapy. 18:995-1001.
    46. Cathepsin G is broadly expressed in acute myeloid leukemia and is an effective immunotherapeutic target. Leukemia.
    47. Batf is important for IL-4 expression in T follicular helper cells. Nature Communications. 6.
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