-
Radaram B, Glazer SE, Yang P, Li CW, Hung MC, Gammon ST, Alauddin M, Piwnica-Worms D. Evaluation of 89Zr-Labeled Anti-PD-L1 Monoclonal Antibodies Using DFO and Novel HOPO Analogues as Chelating Agents for Immuno-PET. ACS Omega. 2023 May 16; 8(19):17181-17194.
PMID: 37214681; PMCID: PMC10193402.
-
Alauddin MM, Khawli LA. Advances in Immuno-PET for the Detection of Cancer and Assessment of Response to Therapy. Curr Med Chem. 2021; 28(4):647-672.
PMID: 32003655.
Citations:
2 Fields:
Translation:
Humans
-
Radaram B, Pisaneschi F, Rao Y, Yang P, Piwnica-Worms D, Alauddin MM. Novel derivatives of anaplastic lymphoma kinase inhibitors: Synthesis, radiolabeling, and preliminary biological studies of fluoroethyl analogues of crizotinib, alectinib, and ceritinib. Eur J Med Chem. 2019 Nov 15; 182:111571.
PMID: 31425908; PMCID: PMC7193943.
Citations:
2 Fields:
Translation:
HumansAnimalsCells
-
Brammer DW, Gillespie PJ, Tian M, Young D, Raveendran M, Williams LE, Gagea M, Benavides FJ, Perez CJ, Broaddus RR, Bernacky BJ, Barnhart KF, Alauddin MM, Bhutani MS, Gibbs RA, Sidman RL, Pasqualini R, Arap W, Rogers J, Abee CR, Gelovani JG. MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques. Proc Natl Acad Sci U S A. 2018 03 13; 115(11):2806-2811.
PMID: 29490919; PMCID: PMC5856559.
Citations:
4 Fields:
Translation:
Animals
-
Alauddin MM. Journey of 2'-deoxy-2'-fluoro-5-methyl-1-?-D-arabinofuranosyluracil (FMAU): from Antiviral Drug to PET Imaging Agent. Curr Med Chem. 2018; 25(16):1867-1878.
PMID: 29189119.
Citations:
2 Fields:
Translation:
HumansAnimals
-
Najjar AM, Manuri PR, Olivares S, Flores L, Mi T, Huls H, Shpall EJ, Champlin RE, Turkman N, Paolillo V, Roszik J, Rabinovich B, Lee DA, Alauddin M, Gelovani J, Cooper LJ. Imaging of Sleeping Beauty-Modified CD19-Specific T Cells Expressing HSV1-Thymidine Kinase by Positron Emission Tomography. Mol Imaging Biol. 2016 12; 18(6):838-848.
PMID: 27246312; PMCID: PMC5096958.
Citations:
13 Fields:
Translation:
HumansAnimalsCells
-
Ferrara F, Staquicini DI, Driessen WHP, D'Angelo S, Dobroff AS, Barry M, Lomo LC, Staquicini FI, Soghomonyan S, Alauddin MM, Flores LG, Lauer RC, Mathew P, Efstathiou E, Aparicio AM, Troncoso P, Navone NM, Logothetis CJ, Gelovani JG, Sidman RL, Pasqualini R, Arap W, Card?-Vila M, Arap MA, Marchi? S. Targeted molecular-genetic imaging and ligand-directed therapy in aggressive variant prostate cancer. Proc Natl Acad Sci U S A. 2016 Nov 08; 113(45):12786-12791.
PMID: 27791181; PMCID: PMC5111687.
-
Perera S, Piwnica-Worms D, Alauddin MM. Synthesis of a [(18)F]-labeled ceritinib analogue for positron emission tomography of anaplastic lymphoma kinase, a receptor tyrosine kinase, in lung cancer. J Labelled Comp Radiopharm. 2016 Mar; 59(3):103-8.
PMID: 26853088; PMCID: PMC4863448.
-
Varkaris A, Corn PG, Parikh NU, Efstathiou E, Song JH, Lee YC, Aparicio A, Hoang AG, Gaur S, Thorpe L, Maity SN, Bar Eli M, Czerniak BA, Shao Y, Alauddin M, Lin SH, Logothetis CJ, Gallick GE. Integrating Murine and Clinical Trials with Cabozantinib to Understand Roles of MET and VEGFR2 as Targets for Growth Inhibition of Prostate Cancer. Clin Cancer Res. 2016 Jan 01; 22(1):107-21.
PMID: 26272062; PMCID: PMC4703437.
Citations:
27 Fields:
Translation:
HumansAnimalsCells
-
Bonomi R, Mukhopadhyay U, Shavrin A, Yeh HH, Majhi A, Dewage SW, Najjar A, Lu X, Tong WP, Alauddin MM, Liu RS, Mangner TJ, Turkman N, Gelovani JG, Cisneros GA. Novel Histone Deacetylase Class IIa Selective Substrate Radiotracers for PET Imaging of Epigenetic Regulation in the Brain. PLoS One. 2015; 10(8):e0133512.
PMID: 26244761; PMCID: PMC4526562.
Citations:
11 Fields:
Translation:
Animals
-
Alauddin MM, De Palatis L. Current and Future Trends in Early Detection of Pancreatic Cancer: Molecular Targets and PET Probes. Curr Med Chem. 2015; 22(29):3370-89.
PMID: 26295468.
Citations:
6 Fields:
Translation:
HumansAnimals
-
Arumugam T, Paolillo V, Young D, Wen X, Logsdon CD, De Palatis L, Alauddin MM. Preliminary evaluation of 1'-[(18)F]fluoroethyl-?-D-lactose ([(18)F]FEL) for detection of pancreatic cancer in nude mouse orthotopic xenografts. Nucl Med Biol. 2014 Nov-Dec; 41(10):833-40.
PMID: 25189831; PMCID: PMC4192027.
Citations:
5 Fields:
Translation:
HumansAnimalsCells
-
Bhatnagar P, Alauddin M, Bankson JA, Kirui D, Seifi P, Huls H, Lee DA, Babakhani A, Ferrari M, Li KC, Cooper LJ. Tumor lysing genetically engineered T cells loaded with multi-modal imaging agents. Sci Rep. 2014 Mar 28; 4:4502.
PMID: 24675806; PMCID: PMC3968458.
Citations:
11 Fields:
Translation:
HumansCells
-
Paolillo V, De Palatis L, Alauddin MM. Optimization of precursor synthesis, formulation and stability of 1'-[18F]fluoroethyl-?-D-lactose ([18F]FEL) for preclinical studies in detection of pancreatic cancer. Nucl Med Biol. 2014 Apr; 41(4):364-70.
PMID: 24508409; PMCID: PMC3962678.
-
Peng Z, Maxwell DS, Sun D, Bhanu Prasad BA, Pal A, Wang S, Balatoni J, Ghosh P, Lim ST, Volgin A, Shavrin A, Alauddin MM, Gelovani JG, Bornmann WG. Imatinib analogs as potential agents for PET imaging of Bcr-Abl and c-KIT expression at a kinase level. Bioorg Med Chem. 2014 Jan 01; 22(1):623-32.
PMID: 24280068; PMCID: PMC4124913.
Citations:
9 Fields:
Translation:
HumansAnimals
-
Chan PC, Wu CY, Chang WT, Lin CY, Tseng YL, Liu RS, Alauddin MM, Lin WJ, Wang HE. Monitoring tumor response with [18F]FMAU in a sarcoma-bearing mouse model after liposomal vinorelbine treatment. Nucl Med Biol. 2013 Nov; 40(8):1035-42.
PMID: 23969084.
Citations: Fields:
Translation:
HumansAnimalsCells
-
Flores LG, Yeh HH, Soghomonyan S, Young D, Bankson J, Hu Q, Alauddin M, Huff V, Gelovani JG. Monitoring therapy with MEK inhibitor U0126 in a novel Wilms tumor model in Wt1 knockout Igf2 transgenic mice using 18F-FDG PET with dual-contrast enhanced CT and MRI: early metabolic response without inhibition of tumor growth. Mol Imaging Biol. 2013 Apr; 15(2):175-85.
PMID: 22875335; PMCID: PMC3591528.
Citations:
8 Fields:
Translation:
Animals
-
Turkman N, Gelovani JG, Alauddin MM. An improved synthesis of 1'-[18F]fluoroethyl-?-D-lactose ([18F]-FEL) for positron emission tomography imaging of pancreatic cancer. J Labelled Comp Radiopharm. 2013 Jun 15; 56(7):351-5.
PMID: 24285438; PMCID: PMC4171848.
Citations:
4 Fields:
Translation:
Humans
-
Alauddin MM. Nucleoside-based probes for imaging tumor proliferation using positron emission tomography. J Labelled Comp Radiopharm. 2013 Mar-Apr; 56(3-4):237-43.
PMID: 24285330.
Citations:
2 Fields:
Translation:
HumansAnimals
-
Turkman N, Paolillo V, Gelovani JG, Alauddin MM. An investigation on stereospecific fluorination at the 2'-arabino-position of a pyrimidine nucleoside: radiosynthesis of 2'-deoxy-2'-[(18)F]fluoro-5-methyl-1-?-D-arabinofuranosyluracil. Tetrahedron. 2012 Dec 16; 68(50):10326-10332.
PMID: 23316091; PMCID: PMC3539786.
-
Yeh HH, Tian M, Hinz R, Young D, Shavrin A, Mukhapadhyay U, Flores LG, Balatoni J, Soghomonyan S, Jeong HJ, Pal A, Uthamanthil R, Jackson JN, Nishii R, Mizuma H, Onoe H, Kagawa S, Higashi T, Fukumitsu N, Alauddin M, Tong W, Herholz K, Gelovani JG. Imaging epigenetic regulation by histone deacetylases in the brain using PET/MRI with ?8F-FAHA. Neuroimage. 2013 Jan 01; 64:630-9.
PMID: 22995777; PMCID: PMC3540799.
Citations:
26 Fields:
Translation:
Animals
-
Nishii R, Tong W, Wendt R, Soghomonyan S, Mukhopadhyay U, Balatoni J, Mawlawi O, Bidaut L, Tinkey P, Borne A, Alauddin M, Gonzalez-Lepera C, Yang B, Gelovani JG. Pharmacokinetics, metabolism, biodistribution, radiation dosimetry, and toxicology of (18)F-fluoroacetate ((18)F-FACE) in non-human primates. Mol Imaging Biol. 2012 Apr; 14(2):213-24.
PMID: 21437735; PMCID: PMC3902791.
Citations:
8 Fields:
Translation:
HumansAnimals
-
Turkman N, Shavrin A, Paolillo V, Yeh HH, Flores L, Soghomonian S, Rabinovich B, Volgin A, Gelovani J, Alauddin M. Synthesis and preliminary evaluation of [18F]-labeled 2-oxoquinoline derivatives for PET imaging of cannabinoid CB2 receptor. Nucl Med Biol. 2012 May; 39(4):593-600.
PMID: 22226022; PMCID: PMC3324652.
Citations:
9 Fields:
Translation:
HumansAnimalsCells
-
Alauddin MM. Positron emission tomography (PET) imaging with (18)F-based radiotracers. Am J Nucl Med Mol Imaging. 2012; 2(1):55-76.
PMID: 23133802; PMCID: PMC3478111.
-
Pal A, Balatoni JA, Mukhopadhyay U, Ogawa K, Gonzalez-Lepera C, Shavrin A, Volgin A, Tong W, Alauddin MM, Gelovani JG. Radiosynthesis and initial in vitro evaluation of [18F]F-PEG6-IPQA--a novel PET radiotracer for imaging EGFR expression-activity in lung carcinomas. Mol Imaging Biol. 2011 Oct; 13(5):853-61.
PMID: 20859697; PMCID: PMC6130206.
Citations:
15 Fields:
Translation:
HumansCells
-
Perin EC, Tian M, Marini FC, Silva GV, Zheng Y, Baimbridge F, Quan X, Fernandes MR, Gahremanpour A, Young D, Paolillo V, Mukhopadhyay U, Borne AT, Uthamanthil R, Brammer D, Jackson J, Decker WK, Najjar AM, Thomas MW, Volgin A, Rabinovich B, Soghomonyan S, Jeong HJ, Rios JM, Steiner D, Robinson S, Mawlawi O, Pan T, Stafford J, Kundra V, Li C, Alauddin MM, Willerson JT, Shpall E, Gelovani JG. Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model. PLoS One. 2011; 6(9):e22949.
PMID: 21912635; PMCID: PMC3164664.
Citations:
23 Fields:
Translation:
AnimalsCells
-
Turkman N, Shavrin A, Ivanov RA, Rabinovich B, Volgin A, Gelovani JG, Alauddin MM. Fluorinated cannabinoid CB2 receptor ligands: synthesis and in vitro binding characteristics of 2-oxoquinoline derivatives. Bioorg Med Chem. 2011 Sep 15; 19(18):5698-707.
PMID: 21872477; PMCID: PMC3174488.
Citations:
7 Fields:
Translation:
HumansCells
-
Paolillo V, Yeh HH, Mukhopadhyay U, Gelovani JG, Alauddin MM. Improved detection and measurement of low levels of [18F]fluoride metabolized from [18F]-labeled pyrimidine nucleoside analogues in biological samples. Nucl Med Biol. 2011 Nov; 38(8):1129-34.
PMID: 21741850; PMCID: PMC3230730.
Citations:
3 Fields:
Translation:
AnimalsCells
-
Chan PC, Wu CY, Chang WY, Chang WT, Alauddin M, Liu RS, Lin WJ, Chen FD, Chen CL, Wang HE. Evaluation of F-18-labeled 5-iodocytidine (18F-FIAC) as a new potential positron emission tomography probe for herpes simplex virus type 1 thymidine kinase imaging. Nucl Med Biol. 2011 Oct; 38(7):987-95.
PMID: 21982570.
Citations:
2 Fields:
Translation:
AnimalsCells
-
Ying Y, Ghosh P, Guo L, Pal A, Mukhapadhyay U, Peng Z, Yeh HH, Bertolini S, Flores LG, Young D, Volgin A, Soghomonyan S, Bornmann W, Logsdon C, Alauddin MM, Gelovani JG. Synthesis and ex vivo autoradiographic evaluation of ethyl-?-D-galactopyranosyl-(1,4')-2'-deoxy-2'-[18F]fluoro-?-D-glucopyranoside--a novel radioligand for lactose-binding protein: implications for early detection of pancreatic carcinomas with PET. Mol Imaging Biol. 2011 Jun; 13(3):536-546.
PMID: 20593279.
Citations:
7 Fields:
Translation:
AnimalsCells
-
Tian M, Ogawa K, Wendt R, Mukhopadhyay U, Balatoni J, Fukumitsu N, Uthamanthil R, Borne A, Brammer D, Jackson J, Mawlawi O, Yang B, Alauddin MM, Gelovani JG. Whole-body biodistribution kinetics, metabolism, and radiation dosimetry estimates of 18F-PEG6-IPQA in nonhuman primates. J Nucl Med. 2011 Jun; 52(6):934-41.
PMID: 21571803; PMCID: PMC4013275.
Citations:
8 Fields:
Translation:
Animals
-
Schwartz DL, Bankson J, Bidaut L, He Y, Williams R, Lemos R, Thitai AK, Oh J, Volgin A, Soghomonyan S, Yeh HH, Nishii R, Mukhopadhay U, Alauddin M, Mushkudiani I, Kuno N, Krishnan S, Bornman W, Lai SY, Powis G, Hazle J, Gelovani J. HIF-1-dependent stromal adaptation to ischemia mediates in vivo tumor radiation resistance. Mol Cancer Res. 2011 Mar; 9(3):259-70.
PMID: 21364021; PMCID: PMC3077053.
Citations:
12 Fields:
Translation:
HumansAnimalsCells
-
Yeh HH, Ogawa K, Balatoni J, Mukhapadhyay U, Pal A, Gonzalez-Lepera C, Shavrin A, Soghomonyan S, Flores L, Young D, Volgin AY, Najjar AM, Krasnykh V, Tong W, Alauddin MM, Gelovani JG. Molecular imaging of active mutant L858R EGF receptor (EGFR) kinase-expressing nonsmall cell lung carcinomas using PET/CT. Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1603-8.
PMID: 21220318; PMCID: PMC3029752.
Citations:
37 Fields:
Translation:
HumansAnimalsCells
-
Staquicini FI, Ozawa MG, Moya CA, Driessen WH, Barbu EM, Nishimori H, Soghomonyan S, Flores LG, Liang X, Paolillo V, Alauddin MM, Basilion JP, Furnari FB, Bogler O, Lang FF, Aldape KD, Fuller GN, Gelovani JG, Sidman RL, Cavenee WK, Pasqualini R, Arap W, H??k M. Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. J Clin Invest. 2011 Jan; 121(1):161-73.
PMID: 21183793; PMCID: PMC3007161.
Citations:
61 Fields:
Translation:
HumansAnimalsCells
-
Wang J, Zhang S, Rabinovich B, Bidaut L, Soghomonyan S, Alauddin MM, Bankson JA, Shpall E, Willerson JT, Gelovani JG, Yeh ET. Human CD34+ cells in experimental myocardial infarction: long-term survival, sustained functional improvement, and mechanism of action. Circ Res. 2010 Jun 25; 106(12):1904-11.
PMID: 20448213; PMCID: PMC2908245.
Citations:
45 Fields:
Translation:
HumansAnimalsCells
-
Alauddin MM, Gelovani JG. Pyrimidine nucleosides in molecular PET imaging of tumor proliferation. Curr Med Chem. 2010; 17(11):1010-29.
PMID: 20156163.
Citations:
3 Fields:
Translation:
Humans
-
Alauddin MM, Gelovani JG. Radiolabeled nucleoside analogues for PET imaging of HSV1-tk gene expression. Curr Top Med Chem. 2010; 10(16):1617-32.
PMID: 20583993.
Citations:
5 Fields:
Translation:
Cells
-
Flores LG, Bertolini S, Yeh HH, Young D, Mukhopadhyay U, Pal A, Ying Y, Volgin A, Shavrin A, Soghomonyan S, Tong W, Bornmann W, Alauddin MM, Logsdon C, Gelovani JG. Detection of pancreatic carcinomas by imaging lactose-binding protein expression in peritumoral pancreas using [18F]fluoroethyl-deoxylactose PET/CT. PLoS One. 2009 Nov 24; 4(11):e7977.
PMID: 19956730; PMCID: PMC2776527.
Citations:
13 Fields:
Translation:
Animals
-
Dotti G, Tian M, Savoldo B, Najjar A, Cooper LJ, Jackson J, Smith A, Mawlawi O, Uthamanthil R, Borne A, Brammer D, Paolillo V, Alauddin M, Gonzalez C, Steiner D, Decker WK, Marini F, Kornblau S, Bollard CM, Shpall EJ, Gelovani JG. Repetitive noninvasive monitoring of HSV1-tk-expressing T cells intravenously infused into nonhuman primates using positron emission tomography and computed tomography with 18F-FEAU. Mol Imaging. 2009 Jul-Aug; 8(4):230-7.
PMID: 19728977; PMCID: PMC3178066.
Citations:
15 Fields:
Translation:
AnimalsCells
-
Schwartz DL, Powis G, Thitai-Kumar A, He Y, Bankson J, Williams R, Lemos R, Oh J, Volgin A, Soghomonyan S, Nishii R, Alauddin M, Mukhopadhay U, Peng Z, Bornmann W, Gelovani J. The selective hypoxia inducible factor-1 inhibitor PX-478 provides in vivo radiosensitization through tumor stromal effects. Mol Cancer Ther. 2009 Apr; 8(4):947-58.
PMID: 19372568; PMCID: PMC2908257.
Citations:
47 Fields:
Translation:
HumansAnimalsCells
-
Wu CY, Chan PC, Chang WT, Liu RS, Alauddin MM, Wang HE. Radiosynthesis of F-18 labeled cytidine analog 2'-fluoro-5-iodo-l-beta-d-arabinofuranosylcytosine ([(18)F]FIAC). Appl Radiat Isot. 2009 Jul-Aug; 67(7-8):1362-5.
PMID: 19324560.
-
Najjar AM, Nishii R, Maxwell DS, Volgin A, Mukhopadhyay U, Bornmann WG, Tong W, Alauddin M, Gelovani JG. Molecular-genetic PET imaging using an HSV1-tk mutant reporter gene with enhanced specificity to acycloguanosine nucleoside analogs. J Nucl Med. 2009 Mar; 50(3):409-16.
PMID: 19223410.
Citations:
12 Fields:
Translation:
HumansAnimalsCells
-
Singh H, Najjar AM, Olivares S, Nishii R, Mukhopadhyay U, Alauddin M, Manuri PR, Huls H, Lee DA, Dotti G, Bollard C, Simmons PJ, Shpall EJ, Champlin RE, Gelovani JG, Cooper LJ. PET imaging of T cells derived from umbilical cord blood. Leukemia. 2009 Mar; 23(3):620-2.
PMID: 18830258; PMCID: PMC5108177.
Citations:
8 Fields:
Translation:
HumansAnimalsCells
-
Ghosh P, Pal A, Shavrin A, Bornmann W, Gelovani JG, Alauddi MM. Synthesis of N3-substituted thymidine analogues for measurement of cellular kinase activity. Med Chem. 2008 Sep; 4(5):503-12.
PMID: 18782048.
Citations:
2 Fields:
Translation:
Cells
-
Mukhopadhyay U, Soghomonyan S, Yeh HH, Flores LG, Shavrin A, Volgin AY, Gelovani JG, Alauddin MM. N(3)-Substituted thymidine analogues V: synthesis and preliminary PET imaging of N(3)-[(18)F]fluoroethyl thymidine and N(3)-[(18)F]fluoropropyl thymidine. Nucl Med Biol. 2008 Aug; 35(6):697-705.
PMID: 18678355.
Citations:
5 Fields:
Translation:
HumansAnimalsCells
-
Hajitou A, Lev DC, Hannay JA, Korchin B, Staquicini FI, Soghomonyan S, Alauddin MM, Benjamin RS, Pollock RE, Gelovani JG, Pasqualini R, Arap W. A preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging. Proc Natl Acad Sci U S A. 2008 Mar 18; 105(11):4471-6.
PMID: 18337507; PMCID: PMC2393798.
Citations:
37 Fields:
Translation:
HumansAnimalsCells
-
Nishii R, Volgin AY, Mawlawi O, Mukhopadhyay U, Pal A, Bornmann W, Gelovani JG, Alauddin MM. Evaluation of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-beta-L: -arabinofuranosyluracil ([18F]-L: -FMAU) as a PET imaging agent for cellular proliferation: comparison with [18F]-D: -FMAU and [18F]FLT. Eur J Nucl Med Mol Imaging. 2008 May; 35(5):990-8.
PMID: 18057932.
Citations:
11 Fields:
Translation:
HumansAnimals
-
Conti PS, Bading JR, Mouton PP, Links JM, Alauddin MM, Fissekis JD, Ravert HT, Hilton J, Wong DF, Anderson JH. In vivo measurement of cell proliferation in canine brain tumor using C-11-labeled FMAU and PET. Nucl Med Biol. 2008 Jan; 35(1):131-41.
PMID: 18158952.
Citations:
7 Fields:
Translation:
AnimalsCells
-
Ponomarev V, Doubrovin M, Shavrin A, Serganova I, Beresten T, Ageyeva L, Cai C, Balatoni J, Alauddin M, Gelovani J. A human-derived reporter gene for noninvasive imaging in humans: mitochondrial thymidine kinase type 2. J Nucl Med. 2007 May; 48(5):819-26.
PMID: 17468435.
Citations:
45 Fields:
Translation:
HumansCells
-
Mukhopadhyay U, Pal A, Gelovani JG, Bornmann W, Alauddin MM. Radiosynthesis of 2'-deoxy-2'-[18F]-fluoro-5-methyl-1-beta-L-arabinofuranosyluracil ([18F]-L-FMAU) for PET. Appl Radiat Isot. 2007 Aug; 65(8):941-6.
PMID: 17517516.
-
Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS. Biodistribution and PET imaging of [(18)F]-fluoroadenosine derivatives. Nucl Med Biol. 2007 Apr; 34(3):267-72.
PMID: 17383576; PMCID: PMC1905838.
Citations:
2 Fields:
Translation:
HumansAnimalsCells
-
Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS. In vivo evaluation of 2'-deoxy-2'-[(18)F]fluoro-5-iodo-1-beta-D-arabinofuranosyluracil ([18F]FIAU) and 2'-deoxy-2'-[18F]fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil ([18F]FEAU) as markers for suicide gene expression. Eur J Nucl Med Mol Imaging. 2007 Jun; 34(6):822-9.
PMID: 17206416.
Citations:
22 Fields:
Translation:
HumansAnimals
-
Soghomonyan S, Hajitou A, Rangel R, Trepel M, Pasqualini R, Arap W, Gelovani JG, Alauddin MM. Molecular PET imaging of HSV1-tk reporter gene expression using [18F]FEAU. Nat Protoc. 2007; 2(2):416-23.
PMID: 17406603.
Citations:
36 Fields:
Translation:
HumansAnimalsCells
-
Hajitou A, Rangel R, Trepel M, Soghomonyan S, Gelovani JG, Alauddin MM, Pasqualini R, Arap W. Design and construction of targeted AAVP vectors for mammalian cell transduction. Nat Protoc. 2007; 2(3):523-31.
PMID: 17406616.
Citations:
51 Fields:
Translation:
AnimalsCells
-
Alauddin MM, Mukhopadhyay U, Gelovani JG. RETRACTED: Synthesis of [(18)F]-labeled N(3)-substituted thymidine analogs: N(3)-[(18)F]fluoroethyl thymidine (N(3)-[(18)F]-FET) and N(3)-[(18)F]fluoropropyl thymidine (N(3)-[(18)F]-FPRT) for PET. Appl Radiat Isot. 2006 Oct 06.
PMID: 17029820.
-
Apisarnthanarax S, Alauddin MM, Mourtada F, Ariga H, Raju U, Mawlawi O, Han D, Bornmann WG, Ajani JA, Milas L, Gelovani JG, Chao KS. Early detection of chemoradioresponse in esophageal carcinoma by 3'-deoxy-3'-3H-fluorothymidine using preclinical tumor models. Clin Cancer Res. 2006 Aug 01; 12(15):4590-7.
PMID: 16899606.
Citations:
31 Fields:
Translation:
HumansAnimalsCells
-
Hajitou A, Trepel M, Lilley CE, Soghomonyan S, Alauddin MM, Marini FC, Restel BH, Ozawa MG, Moya CA, Rangel R, Sun Y, Zaoui K, Schmidt M, von Kalle C, Weitzman MD, Gelovani JG, Pasqualini R, Arap W. A hybrid vector for ligand-directed tumor targeting and molecular imaging. Cell. 2006 Apr 21; 125(2):385-98.
PMID: 16630824.
Citations:
116 Fields:
Translation:
AnimalsCells
-
Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS. Synthesis and evaluation of 2'-deoxy-2'-18F-fluoro-5-fluoro-1-beta-D-arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression. J Nucl Med. 2004 Dec; 45(12):2063-9.
PMID: 15585483.
Citations:
12 Fields:
Translation:
HumansAnimalsCells
-
Bading JR, Shahinian AH, Vail A, Bathija P, Koszalka GW, Koda RT, Alauddin MM, Fissekis JD, Conti PS. Pharmacokinetics of the thymidine analog 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (FMAU) in tumor-bearing rats. Nucl Med Biol. 2004 May; 31(4):407-18.
PMID: 15093810.
Citations:
11 Fields:
Translation:
AnimalsCells
-
Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS. Synthesis of 2'-deoxy-2'-[18F]fluoro-5-bromo-1-beta-D-arabinofuranosyluracil ([18F]-FBAU) and 2'-deoxy-2'-[18F]fluoro-5-chloro-1-beta-D-arabinofuranosyl-uracil ([18F]-FCAU), and their biological evaluation as markers for gene expression. Nucl Med Biol. 2004 May; 31(4):399-405.
PMID: 15093809.
Citations:
9 Fields:
Translation:
HumansAnimals
-
Alauddin MM, Shahinian A, Gordon EM, Conti PS. Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model. Mol Imaging. 2004 Apr; 3(2):76-84.
PMID: 15296672.
Citations:
20 Fields:
Translation:
HumansAnimalsCells
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Khawli LA, Alauddin MM, Hu P, Epstein AL. Tumor targeting properties of indium-111 labeled genetically engineered Fab' and F(ab')2 constructs of chimeric tumor necrosis treatment (chTNT)-3 antibody. Cancer Biother Radiopharm. 2003 Dec; 18(6):931-40.
PMID: 14969605.
Citations:
4 Fields:
Translation:
Animals
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Bading JR, Yoo PB, Fissekis JD, Alauddin MM, D'Argenio DZ, Conti PS. Kinetic modeling of 5-fluorouracil anabolism in colorectal adenocarcinoma: a positron emission tomography study in rats. Cancer Res. 2003 Jul 01; 63(13):3667-74.
PMID: 12839957.
Citations:
7 Fields:
Translation:
Animals
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Alauddin MM, Louie AY, Shahinian A, Meade TJ, Conti PS. Receptor mediated uptake of a radiolabeled contrast agent sensitive to beta-galactosidase activity. Nucl Med Biol. 2003 Apr; 30(3):261-5.
PMID: 12745017.
Citations:
8 Fields:
Translation:
HumansAnimals
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Tjuvajev JG, Doubrovin M, Akhurst T, Cai S, Balatoni J, Alauddin MM, Finn R, Bornmann W, Thaler H, Conti PS, Blasberg RG. Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression. J Nucl Med. 2002 Aug; 43(8):1072-83.
PMID: 12163634.
Citations:
72 Fields:
Translation:
AnimalsCells
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Alauddin MM, Shahinian A, Gordon EM, Conti PS. Evaluation of 2'-deoxy-2'-flouro-5-methyl-1-beta-D-arabinofuranosyluracil as a potential gene imaging agent for HSV-tk expression in vivo. Mol Imaging. 2002 Apr-Jun; 1(2):74-81.
PMID: 12920847.
Citations:
13 Fields:
Translation:
HumansAnimalsCells
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Alauddin MM, Shahinian A, Gordon EM, Bading JR, Conti PS. Preclinical evaluation of the penciclovir analog 9-(4-[(18)F]fluoro-3-hydroxymethylbutyl)guanine for in vivo measurement of suicide gene expression with PET. J Nucl Med. 2001 Nov; 42(11):1682-90.
PMID: 11696640.
Citations:
16 Fields:
Translation:
HumansAnimalsCells
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Bading JR, Alauddin MM, Fissekis JD, Shahinian AH, Joung J, Spector T, Conti PS. Blocking catabolism with eniluracil enhances PET studies of 5-[18F]fluorouracil pharmacokinetics. J Nucl Med. 2000 Oct; 41(10):1714-24.
PMID: 11038003.
Citations:
7 Fields:
Translation:
Animals
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Hornick JL, Sharifi J, Khawli LA, Hu P, Bai WG, Alauddin MM, Mizokami MM, Epstein AL. Single amino acid substitution in the Fc region of chimeric TNT-3 antibody accelerates clearance and improves immunoscintigraphy of solid tumors. J Nucl Med. 2000 Feb; 41(2):355-62.
PMID: 10688122.
Citations:
9 Fields:
Translation:
HumansAnimalsCells
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Alauddin MM, Shahinian A, Kundu RK, Gordon EM, Conti PS. Evaluation of 9-[(3-18F-fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]-FHPG) in vitro and in vivo as a probe for PET imaging of gene incorporation and expression in tumors. Nucl Med Biol. 1999 May; 26(4):371-6.
PMID: 10382839.
Citations:
8 Fields:
Translation:
HumansAnimalsCells
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Alauddin MM, Conti PS. Synthesis and preliminary evaluation of 9-(4-[18F]-fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG): a new potential imaging agent for viral infection and gene therapy using PET. Nucl Med Biol. 1998 Apr; 25(3):175-80.
PMID: 9620620.
Citations:
35 Fields:
Translation:
HumansCells
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Alauddin MM, Fissekis JD, Conti PS. Alpha-alkylation of amino acid derivatives: synthesis and chiral resolution of [11C]beta-aminoisobutyric acid. Nucl Med Biol. 1997 Nov; 24(8):771-5.
PMID: 9428604.
Citations: Fields:
Translation:
Cells
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Alauddin MM, Conti PS, Mazza SM, Hamzeh FM, Lever JR. 9-[(3-[18F]-fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]-FHPG): a potential imaging agent of viral infection and gene therapy using PET. Nucl Med Biol. 1996 Aug; 23(6):787-92.
PMID: 8940722.
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Khawli LA, Glasky MS, Alauddin MM, Epstein AL. Improved tumor localization and radioimaging with chemically modified monoclonal antibodies. Cancer Biother Radiopharm. 1996 Jun; 11(3):203-15.
PMID: 10851539.
Citations:
12 Fields:
Translation:
HumansAnimalsCells
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Schmall B, Conti PS, Alauddin MM. Synthesis of [11C-methyl]-alpha-aminoisobutyric acid (AIB). Nucl Med Biol. 1996 Apr; 23(3):263-6.
PMID: 8782235.
Citations:
1 Fields:
Translation:
HumansAnimals
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Alauddin MM, Ravert HT, Musachio JL, Mathews WB, Dannals RF, Conti PS. Selective alkylation of pyrimidyl dianions III: no-carrier-added synthesis of [11C-methyl]-thymidine. Nucl Med Biol. 1995 Aug; 22(6):791-4.
PMID: 8535340.
Citations:
1 Fields:
Translation:
HumansAnimalsCells
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Conti PS, Alauddin MM, Fissekis JR, Schmall B, Watanabe KA. Synthesis of 2'-fluoro-5-[11C]-methyl-1-beta-D-arabinofuranosyluracil ([11C]-FMAU): a potential nucleoside analog for in vivo study of cellular proliferation with PET. Nucl Med Biol. 1995 Aug; 22(6):783-9.
PMID: 8535339.
Citations:
18 Fields:
Translation:
HumansAnimals
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Hu P, Glasky MS, Yun A, Alauddin MM, Hornick JL, Khawli LA, Epstein AL. A human-mouse chimeric Lym-1 monoclonal antibody with specificity for human lymphomas expressed in a baculovirus system. Hum Antibodies Hybridomas. 1995; 6(2):57-67.
PMID: 7492752.
Citations:
4 Fields:
Translation:
HumansAnimalsCells
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Conti PS, Hilton J, Wong DF, Alauddin MM, Dannals RF, Ravert HT, Wilson AA, Anderson JH. High performance liquid chromatography of carbon-11 labeled thymidine and its major catabolites for clinical PET studies. Nucl Med Biol. 1994 Nov; 21(8):1045-51.
PMID: 9234362.
Citations:
4 Fields:
Translation:
HumansAnimals
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John E, Thakur ML, Wilder S, Alauddin MM, Epstein AL. Technetium-99m-labeled monoclonal antibodies: influence of technetium-99m binding sites. J Nucl Med. 1994 May; 35(5):876-81.
PMID: 8176476.
Citations:
3 Fields:
Translation:
AnimalsCells
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Alauddin MM, Khawli LA, Epstein AL. An improved method of direct labeling monoclonal antibodies with 99mTc. Int J Rad Appl Instrum B. 1992 May; 19(4):445-54.
PMID: 1526809.
Citations:
1 Fields:
Translation:
HumansAnimals
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Najafi A, Alauddin MM, Sosa A, Ma GQ, Chen DC, Epstein AL, Siegel ME. The evaluation of 186Re-labeled antibodies using N2S4 chelate in vitro and in vivo using tumor-bearing nude mice. Int J Rad Appl Instrum B. 1992 Feb; 19(2):205-12.
PMID: 1601674.
Citations:
4 Fields:
Translation:
HumansAnimals
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LeBerthon B, Khawli LA, Alauddin M, Miller GK, Charak BS, Mazumder A, Epstein AL. Enhanced tumor uptake of macromolecules induced by a novel vasoactive interleukin 2 immunoconjugate. Cancer Res. 1991 May 15; 51(10):2694-8.
PMID: 2021947.
Citations:
13 Fields:
Translation:
HumansAnimalsCells
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Najafi A, Alauddin MM, Siegel ME, Epstein AL. Synthesis and preliminary evaluation of a new chelate N2S4 for use in labeling proteins with metallic radionuclides. Int J Rad Appl Instrum B. 1991; 18(2):179-85.
PMID: 2026493.
Citations:
3 Fields:
Translation:
Cells
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N3-Substituted thymidine analogues III. Journal of Labelled Compounds and Radiopharmaceuticals. 50:1185-1191.
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Radiosynthesis of 2-deoxy-2-[F-18]flouro-1, 3, 5-tri-O-benzoyl-α-D-arabinofuranose. Journal of Labelled Compounds and Radiopharmaceuticals. 42.
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Novel histone deacetylase class IIa selective substrate radiotracers for PET imaging of epigenetic regulation in the brain. PLoS One. 10.
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Integrating murine and clinical trials with cabozantinib to understand roles of MET and VEGFR2 as targets for growth inhibition of prostate cancer. Clinical Cancer Research. 22:107-121.
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Ammonia chemical ionization mass spectrometry. Mass Spectrometry Reviews. 5:381-465.
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Journal of Labelled Compounds and Radiopharmaceuticals. 46:285-289.
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A fully automated synthesis of [18F]-FEAU and [ 18F]-FMAU using a novel dual reactor radiosynthesis module. Journal of Labelled Compounds and Radiopharmaceuticals. 52:553-558.
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Stereospecific fluorination of 1,3,5-tri-O-benzoyl-α-D-ribofuranose-2-sulfonate esters. Journal of Fluorine Chemistry. 106:87-91.
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Authors' reply to letter to the editors by S. J. Mather. Nuclear Medicine and Biology. 20:376.
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Synthesis of [18F]-labeled adenosine analogues as potential PET imaging agents. Journal of Labelled Compounds and Radiopharmaceuticals. 46:805-814.
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Synthesis of a [18F]-labeled ceritinib analogue for positron emission tomography of anaplastic lymphoma kinase, a receptor tyrosine kinase, in lung cancer. Journal of Labelled Compounds and Radiopharmaceuticals. 59:103-108.
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Tetrahedron. 68:10326-10332.
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Versatile precursors for the synthesis of enynes and enediynes. Tetrahedron Letters. 30:6997-7000.
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Targeted molecular-genetic imaging and liganddirected therapy in aggressive variant prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 113:12786-12791.
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Journal of Labelled Compounds and Radiopharmaceuticals. 48:941-950.
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Expedient synthesis of [18F]-labeled α-trifluoromethyl ketones. Journal of Labelled Compounds and Radiopharmaceuticals. 46:1087-1092.
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Radiosynthesis of N5-[18F]fluoroacetylornithine (N5-[18F]FAO) for PET imaging of ornithine decarboxylase (ODC) in malignant tumors. Journal of Labelled Compounds and Radiopharmaceuticals. 54:33-37.
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Asymmetric lignan synthesis. Journal of Organic Chemistry. 51:3490-3493.
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Orthoquinodimethanes. Tetrahedron. 43:2873-2889.
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Journal of Labelled Compounds and Radiopharmaceuticals. 53:782-786.
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Imaging of Sleeping Beauty-Modified CD19-Specific T Cells Expressing HSV1-Thymidine Kinase by Positron Emission Tomography. Molecular Imaging and Biology. 1-11.
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Journal of Labelled Compounds and Radiopharmaceuticals. 54:233-238.
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A general method of halogenation for synthesis of α-halodifluoromethyl ketones and [18F]-labeled trifluoromethyl ketones. Journal of Fluorine Chemistry. 121:239-243.
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N3-Substituted thymidine analogues. Current Radiopharmaceuticals. 2:2-8.
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Synthetic Communications. 32:1757-1764.
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Selective alkylation of pyrimidyl dianions II. Tetrahedron. 50:1699-1706.
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Synthesis of [18F]-labeled N-3(substituted) thymidine analogues. Journal of Labelled Compounds and Radiopharmaceuticals. 49:1079-1088.
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Radiosynthesis of 6-([18F]fluoroacetamido)-1-hexanoic-anilide ([18F]FAHA) for PET imaging of histone deacetylase (HDAC). Journal of Labelled Compounds and Radiopharmaceuticals. 49:997-1006.
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Journal of Labelled Compounds and Radiopharmaceuticals. 45:583-590.
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Improved immunotargeting of tumors with biotinylated monoclonal antibodies and radiolabeled streptavidin. Antibody, Immunoconjugates, and Radiopharmaceuticals. 6:13-27.