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FRANCOIS-XAVIER CLARET

TitleAssociate Professor
InstitutionMD Anderson
DepartmentSystems Biology
Address6565 MD Anderson Blvd
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Peng X, Huang X, Zhang S, Zhang N, Huang S, Wang Y, Zhong Z, Zhu S, Gao H, Yu Z, Yan X, Tao Z, Dai Y, Zhang Z, Chen X, Wang F, Claret FX, Elkabets M, Ji N, Zhong Y, Kong D. Sequential Inhibition of PARP and BET as a Rational Therapeutic Strategy for Glioblastoma. Adv Sci (Weinh). 2024 Aug; 11(30):e2307747. PMID: 38896791; PMCID: PMC11321613.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    2. Peng X, Wang Y, Zhang S, Tao Z, Dai Y, Claret FX, Elkabets M, Lin HW, Chen ZS, Kong D. Stellettin B renders glioblastoma vulnerable to poly (ADP-ribose) polymerase inhibitors via suppressing homology-directed repair. Signal Transduct Target Ther. 2023 03 22; 8(1):119. PMID: 36944633; PMCID: PMC10030553.
      Citations:    Fields:    Translation:Humans
    3. Peng X, Zhang S, Wang Y, Zhou Z, Yu Z, Zhong Z, Zhang L, Chen ZS, Claret FX, Elkabets M, Wang F, Sun F, Wang R, Liang H, Lin HW, Kong D. Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair. Adv Sci (Weinh). 2023 01; 10(3):e2205529. PMID: 36453577; PMCID: PMC9875605.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    4. Peng X, Zhang S, Jiao W, Zhong Z, Yang Y, Claret FX, Elkabets M, Wang F, Wang R, Zhong Y, Chen ZS, Kong D. Correction to: Hydroxychloroquine synergizes with the PI3K inhibitor BKM120 to exhibit antitumor efficacy independent of autophagy. J Exp Clin Cancer Res. 2021 Dec 20; 40(1):396. PMID: 34930384; PMCID: PMC8686337.
      Citations:    Fields:    
    5. Peng X, Zhang S, Jiao W, Zhong Z, Yang Y, Claret FX, Elkabets M, Wang F, Wang R, Zhong Y, Chen ZS, Kong D. Hydroxychloroquine synergizes with the PI3K inhibitor BKM120 to exhibit antitumor efficacy independent of autophagy. J Exp Clin Cancer Res. 2021 Nov 29; 40(1):374. PMID: 34844627; PMCID: PMC8628289.
      Citations: 3     Fields:    Translation:HumansAnimals
    6. Ma W, Yao Y, Xu G, Wu X, Li J, Wang G, Chen X, Wang K, Chen Y, Guo Y, Li Y, Tan D, Guo H, Liu Z, Yuan Y, Claret FX. Identification of a seven-long non-coding RNA signature associated with Jab1/CSN5 in predicting hepatocellular carcinoma. Cell Death Discov. 2021 Jul 10; 7(1):178. PMID: 34247194; PMCID: PMC8272716.
      Citations: 2     
    7. Chen C, Hou J, Yu S, Li W, Wang X, Sun H, Qin T, Claret FX, Guo H, Liu Z. Role of cancer-associated fibroblasts in the resistance to antitumor therapy, and their potential therapeutic mechanisms in non-small cell lung cancer. Oncol Lett. 2021 May; 21(5):413. PMID: 33841574; PMCID: PMC8020389.
      Citations: 6     
    8. Pan Y, Zhou F, Zhang R, Claret FX. Correction: Stat3 inhibitor stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinoma. PLoS One. 2020; 15(8):e0237943. PMID: 32790751; PMCID: PMC7425959.
      Citations: 1     Fields:    
    9. Liang J, Wang L, Wang C, Shen J, Su B, Marisetty AL, Fang D, Kassab C, Jeong KJ, Zhao W, Lu Y, Jain AK, Zhou Z, Liang H, Sun SC, Lu C, Xu ZX, Yu Q, Shao S, Chen X, Gao M, Claret FX, Ding Z, Chen J, Chen P, Barton MC, Peng G, Mills GB, Heimberger AB. Verteporfin Inhibits PD-L1 through Autophagy and the STAT1-IRF1-TRIM28 Signaling Axis, Exerting Antitumor Efficacy. Cancer Immunol Res. 2020 07; 8(7):952-965. PMID: 32265228; PMCID: PMC8204534.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    10. Yu S, Wang Y, Hou J, Li W, Wang X, Xiang L, Tan D, Wang W, Jiang L, Claret FX, Jiao M, Guo H. Tumor-infiltrating immune cells in hepatocellular carcinoma: Tregs is correlated with poor overall survival. PLoS One. 2020; 15(4):e0231003. PMID: 32240238; PMCID: PMC7117689.
      Citations: 16     Fields:    Translation:HumansCells
    11. Wang S, Oh DY, Leventaki V, Drakos E, Zhang R, Sahin AA, Resetkova E, Edgerton ME, Wu W, Claret FX. MicroRNA-17 acts as a tumor chemosensitizer by targeting JAB1/CSN5 in triple-negative breast cancer. Cancer Lett. 2019 11 28; 465:12-23. PMID: 31473252.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    12. Leventaki V, Rassidakis GZ, Claret FX, Atsaves V. AP-1 Transcription Factors as Regulators of Immune Responses in Cancer. Cancers (Basel). 2019 Jul 23; 11(7). PMID: 31340499; PMCID: PMC6678392.
      Citations: 55     
    13. Xiao H, Claret FX, Shen Q. The novel Jab1 inhibitor CSN5i-3 suppresses cell proliferation and induces apoptosis in human breast cancer cells. Neoplasma. 2019 May 23; 66(3):481-486. PMID: 30868895.
      Citations:    
    14. Wang Y, Ruan Z, Yu S, Tian T, Liang X, Jing L, Li W, Wang X, Xiang L, Claret FX, Nan K, Guo H. A four-methylated mRNA signature-based risk score system predicts survival in patients with hepatocellular carcinoma. Aging (Albany NY). 2019 01 10; 11(1):160-173. PMID: 30631005; PMCID: PMC6339794.
      Citations:    
    15. Liu G, Yu M, Wu B, Guo S, Huang X, Zhou F, Claret FX, Pan Y. Jab1/Cops5 contributes to chemoresistance in breast cancer by regulating Rad51. Cell Signal. 2019 01; 53:39-48. PMID: 30244171.
      Citations: 8     Fields:    Translation:HumansCells
    16. Liu G, Claret FX, Zhou F, Pan Y. Jab1/COPS5 as a Novel Biomarker for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Human Cancer. Front Pharmacol. 2018; 9:135. PMID: 29535627; PMCID: PMC5835092.
      Citations: 18     
    17. Yu S, Wang Y, Jing L, Claret FX, Li Q, Tian T, Liang X, Ruan Z, Jiang L, Yao Y, Nan K, Lv Y, Guo H. Autophagy in the "inflammation-carcinogenesis" pathway of liver and HCC immunotherapy. Cancer Lett. 2017 12 28; 411:82-89. PMID: 28987386.
      Citations:    
    18. Zhou F, Pan Y, Wei Y, Zhang R, Bai G, Shen Q, Meng S, Le XF, Andreeff M, Claret FX. Jab1/Csn5-Thioredoxin Signaling in Relapsed Acute Monocytic Leukemia under Oxidative Stress. Clin Cancer Res. 2017 Aug 01; 23(15):4450-4461. PMID: 28270496; PMCID: PMC5861712.
      Citations: 23     Fields:    Translation:HumansCells
    19. Wang S, Wu W, Claret FX. Mutual regulation of microRNAs and DNA methylation in human cancers. Epigenetics. 2017 Mar 04; 12(3):187-197. PMID: 28059592; PMCID: PMC5406215.
      Citations: 50     Fields:    Translation:HumansCells
    20. Xu T, Su B, Huang P, Wei W, Deng Y, Sehgal V, Wang D, Jiang J, Zhang G, Li A, Yang H, Claret FX. Novel biomarkers of nasopharyngeal carcinoma metastasis risk identified by reverse phase protein array based tumor profiling with consideration of plasma Epstein-Barr virus DNA load. Proteomics Clin Appl. 2017 05; 11(5-6). PMID: 27883284.
      Citations: 4     Fields:    Translation:HumansCells
    21. Hua WF, Zhong Q, Xia TL, Chen Q, Zhang MY, Zhou AJ, Tu ZW, Qu C, Li MZ, Xia YF, Wang HY, Xie D, Claret FX, Song EW, Zeng MS. RBM24 suppresses cancer progression by upregulating miR-25 to target MALAT1 in nasopharyngeal carcinoma. Cell Death Dis. 2016 09 01; 7(9):e2352. PMID: 27584791; PMCID: PMC5059856.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    22. Pan Y, Wang S, Su B, Zhou F, Zhang R, Xu T, Zhang R, Leventaki V, Drakos E, Liu W, Claret FX. Stat3 contributes to cancer progression by regulating Jab1/Csn5 expression. Oncogene. 2017 02 23; 36(8):1069-1079. PMID: 27524414; PMCID: PMC5311075.
      Citations:    
    23. Wang S, Pan Y, Zhang R, Xu T, Wu W, Zhang R, Wang C, Huang H, Calin CA, Yang H, Claret FX. Hsa-miR-24-3p increases nasopharyngeal carcinoma radiosensitivity by targeting both the 3'UTR and 5'UTR of Jab1/CSN5. Oncogene. 2016 11 24; 35(47):6096-6108. PMID: 27157611; PMCID: PMC5102828.
      Citations:    
    24. Guo H, Jing L, Cheng Y, Atsaves V, Lv Y, Wu T, Su R, Zhang Y, Zhang R, Liu W, Rassidakis GZ, Wei Y, Nan K, Claret FX. Down-regulation of the cyclin-dependent kinase inhibitor p57 is mediated by Jab1/Csn5 in hepatocarcinogenesis. Hepatology. 2016 Mar; 63(3):898-913. PMID: 26606000.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    25. Atsaves V, Zhang R, Ruder D, Pan Y, Leventaki V, Rassidakis GZ, Claret FX. Constitutive control of AKT1 gene expression by JUNB/CJUN in ALK+ anaplastic large-cell lymphoma: a novel crosstalk mechanism. Leukemia. 2015 Nov; 29(11):2162-72. PMID: 25987255; PMCID: PMC4633353.
      Citations: 9     Fields:    Translation:HumansCells
    26. Wang S, Zhang R, Claret FX, Yang H. Involvement of microRNA-24 and DNA methylation in resistance of nasopharyngeal carcinoma to ionizing radiation. Mol Cancer Ther. 2014 Dec; 13(12):3163-74. PMID: 25319395; PMCID: PMC4258432.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    27. Atsaves V, Lekakis L, Drakos E, Leventaki V, Ghaderi M, Baltatzis GE, Chioureas D, Jones D, Feretzaki M, Liakou C, Panayiotidis P, Gorgoulis V, Patsouris E, Medeiros LJ, Claret FX, Rassidakis GZ. The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK+ anaplastic large cell lymphoma. Br J Haematol. 2014 Nov; 167(4):514-23. PMID: 25145835.
      Citations: 13     Fields:    Translation:HumansCellsCTClinical Trials
    28. Vu T, Sliwkowski MX, Claret FX. Personalized drug combinations to overcome trastuzumab resistance in HER2-positive breast cancer. Biochim Biophys Acta. 2014 Dec; 1846(2):353-65. PMID: 25065528; PMCID: PMC4261073.
      Citations: 19     Fields:    Translation:Humans
    29. Pan Y, Yang H, Claret FX. Emerging roles of Jab1/CSN5 in DNA damage response, DNA repair, and cancer. Cancer Biol Ther. 2014 Mar 01; 15(3):256-62. PMID: 24495954; PMCID: PMC3974825.
      Citations: 27     Fields:    Translation:HumansCells
    30. Zhou F, Meng S, Song H, Claret FX. Dickkopf-1 is a key regulator of myeloma bone disease: opportunities and challenges for therapeutic intervention. Blood Rev. 2013 Nov; 27(6):261-7. PMID: 24054128; PMCID: PMC4133945.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    31. Pan Y, Wang M, Bu X, Zuo Y, Wang S, Wang D, Liu Q, Su B, Xu T, Wang C, Claret FX, Yang H. Curcumin analogue T83 exhibits potent antitumor activity and induces radiosensitivity through inactivation of Jab1 in nasopharyngeal carcinoma. BMC Cancer. 2013 Jul 01; 13:323. PMID: 23815987; PMCID: PMC3706359.
      Citations: 14     Fields:    Translation:HumansCells
    32. Zhou F, Shen Q, Claret FX. Novel roles of reactive oxygen species in the pathogenesis of acute myeloid leukemia. J Leukoc Biol. 2013 Sep; 94(3):423-9. PMID: 23715741; PMCID: PMC4051257.
      Citations: 39     Fields:    Translation:HumansCells
    33. Pan Y, Zhou F, Zhang R, Claret FX. Stat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinoma. PLoS One. 2013; 8(1):e54565. PMID: 23382914; PMCID: PMC3558509.
      Citations: 56     Fields:    Translation:HumansCells
    34. Pan Y, Claret FX. Targeting Jab1/CSN5 in nasopharyngeal carcinoma. Cancer Lett. 2012 Dec 30; 326(2):155-60. PMID: 22867945; PMCID: PMC3474602.
      Citations: 24     Fields:    Translation:HumansCells
    35. Pan Y, Zhang Q, Atsaves V, Yang H, Claret FX. Suppression of Jab1/CSN5 induces radio- and chemo-sensitivity in nasopharyngeal carcinoma through changes to the DNA damage and repair pathways. Oncogene. 2013 May 30; 32(22):2756-66. PMID: 22797071; PMCID: PMC3566273.
      Citations: 40     Fields:    Translation:HumansCells
    36. Vu T, Claret FX. Trastuzumab: updated mechanisms of action and resistance in breast cancer. Front Oncol. 2012; 2:62. PMID: 22720269; PMCID: PMC3376449.
      Citations: 193     
    37. Pan Y, Zhang Q, Tian L, Wang X, Fan X, Zhang H, Claret FX, Yang H. Jab1/CSN5 negatively regulates p27 and plays a role in the pathogenesis of nasopharyngeal carcinoma. Cancer Res. 2012 Apr 01; 72(7):1890-900. PMID: 22350412; PMCID: PMC3460549.
      Citations: 40     Fields:    Translation:HumansCells
    38. Zhang Q, Claret FX. Phosphatases: the new brakes for cancer development? Enzyme Res. 2012; 2012:659649. PMID: 22121480; PMCID: PMC3206369.
      Citations: 29     
    39. Le XF, Mao W, He G, Claret FX, Xia W, Ahmed AA, Hung MC, Siddik ZH, Bast RC. The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells. J Natl Cancer Inst. 2011 Sep 21; 103(18):1403-22. PMID: 21813412; PMCID: PMC3176777.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    40. Shackleford TJ, Zhang Q, Tian L, Vu TT, Korapati AL, Baumgartner AM, Le XF, Liao WS, Claret FX. Stat3 and CCAAT/enhancer binding protein beta (C/EBP-beta) regulate Jab1/CSN5 expression in mammary carcinoma cells. Breast Cancer Res. 2011 Jun 20; 13(3):R65. PMID: 21689417; PMCID: PMC3218954.
      Citations: 26     Fields:    Translation:HumansCells
    41. Drakos E, Singh RR, Rassidakis GZ, Schlette E, Li J, Claret FX, Ford RJ, Vega F, Medeiros LJ. Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21). Leukemia. 2011 May; 25(5):856-67. PMID: 21394100; PMCID: PMC3094765.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    42. Drakos E, Leventaki V, Atsaves V, Schlette EJ, Lin P, Vega F, Miranda RN, Claret FX, Medeiros LJ, Rassidakis GZ. Expression of serine 194-phosphorylated Fas-associated death domain protein correlates with proliferation in B-cell non-Hodgkin lymphomas. Hum Pathol. 2011 Aug; 42(8):1117-24. PMID: 21315423; PMCID: PMC4089890.
      Citations: 8     Fields:    Translation:HumansCells
    43. Shackleford TJ, Claret FX. JAB1/CSN5: a new player in cell cycle control and cancer. Cell Div. 2010 Oct 18; 5:26. PMID: 20955608; PMCID: PMC2976740.
      Citations: 72     
    44. Tian L, Peng G, Parant JM, Leventaki V, Drakos E, Zhang Q, Parker-Thornburg J, Shackleford TJ, Dai H, Lin SY, Lozano G, Rassidakis GZ, Claret FX. Essential roles of Jab1 in cell survival, spontaneous DNA damage and DNA repair. Oncogene. 2010 Nov 18; 29(46):6125-37. PMID: 20802511; PMCID: PMC3495558.
      Citations: 33     Fields:    Translation:AnimalsCells
    45. Vivas-Mejia P, Benito JM, Fernandez A, Han HD, Mangala L, Rodriguez-Aguayo C, Chavez-Reyes A, Lin YG, Carey MS, Nick AM, Stone RL, Kim HS, Claret FX, Bornmann W, Hennessy BT, Sanguino A, Peng Z, Sood AK, Lopez-Berestein G. c-Jun-NH2-kinase-1 inhibition leads to antitumor activity in ovarian cancer. Clin Cancer Res. 2010 Jan 01; 16(1):184-94. PMID: 20028751; PMCID: PMC3716580.
      Citations: 24     Fields:    Translation:HumansAnimals
    46. Shin S, Asano T, Yao Y, Zhang R, Claret FX, Korc M, Sabapathy K, Menter DG, Abbruzzese JL, Reddy SAG. Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism. Mol Cancer Res. 2009 May; 7(5):745-754. PMID: 19435822; PMCID: PMC4854281.
      Citations: 10     Fields:    Translation:HumansCells
    47. Estrella VC, Eder AM, Liu S, Pustilnik TB, Tabassam FH, Claret FX, Gallick GE, Mills GB, Wiener JR. Lysophosphatidic acid induction of urokinase plasminogen activator secretion requires activation of the p38MAPK pathway. Int J Oncol. 2007 Aug; 31(2):441-9. PMID: 17611702.
      Citations: 15     Fields:    Translation:HumansCells
    48. Leventaki V, Drakos E, Medeiros LJ, Lim MS, Elenitoba-Johnson KS, Claret FX, Rassidakis GZ. NPM-ALK oncogenic kinase promotes cell-cycle progression through activation of JNK/cJun signaling in anaplastic large-cell lymphoma. Blood. 2007 Sep 01; 110(5):1621-30. PMID: 17416736.
      Citations: 30     Fields:    Translation:HumansCells
    49. Kouvaraki MA, Korapati AL, Rassidakis GZ, Tian L, Zhang Q, Chiao P, Ho L, Evans DB, Claret FX. Potential role of Jun activation domain-binding protein 1 as a negative regulator of p27kip1 in pancreatic adenocarcinoma. Cancer Res. 2006 Sep 01; 66(17):8581-9. PMID: 16951171; PMCID: PMC1780177.
      Citations: 26     Fields:    Translation:Humans
    50. Vega F, Medeiros LJ, Leventaki V, Atwell C, Cho-Vega JH, Tian L, Claret FX, Rassidakis GZ. Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. Cancer Res. 2006 Jul 01; 66(13):6589-97. PMID: 16818631; PMCID: PMC4839264.
      Citations: 74     Fields:    Translation:HumansCells
    51. Kim HJ, Chakravarti N, Oridate N, Choe C, Claret FX, Lotan R. N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells. Oncogene. 2006 May 04; 25(19):2785-94. PMID: 16407847; PMCID: PMC1458365.
      Citations: 24     Fields:    Translation:HumansCells
    52. Rassidakis GZ, Thomaides A, Atwell C, Ford R, Jones D, Claret FX, Medeiros LJ. JunB expression is a common feature of CD30+ lymphomas and lymphomatoid papulosis. Mod Pathol. 2005 Oct; 18(10):1365-70. PMID: 15920551; PMCID: PMC1382062.
      Citations: 25     Fields:    Translation:Humans
    53. Zhang Q, Tian L, Mansouri A, Korapati AL, Johnson TJ, Claret FX. Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells. FEBS Lett. 2005 Jul 18; 579(18):3932-40. PMID: 15996662; PMCID: PMC1366489.
      Citations: 18     Fields:    Translation:HumansCells
    54. Rassidakis GZ, Feretzaki M, Atwell C, Grammatikakis I, Lin Q, Lai R, Claret FX, Medeiros LJ, Amin HM. Inhibition of Akt increases p27Kip1 levels and induces cell cycle arrest in anaplastic large cell lymphoma. Blood. 2005 Jan 15; 105(2):827-9. PMID: 15374880; PMCID: PMC1382060.
      Citations: 41     Fields:    Translation:HumansCells
    55. Fang X, Yu S, Bast RC, Liu S, Xu HJ, Hu SX, LaPushin R, Claret FX, Aggarwal BB, Lu Y, Mills GB. Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells. J Biol Chem. 2004 Mar 05; 279(10):9653-61. PMID: 14670967.
      Citations: 88     Fields:    Translation:HumansCells
    56. Esteva FJ, Sahin AA, Rassidakis GZ, Yuan LX, Smith TL, Yang Y, Gilcrease MZ, Cristofanilli M, Nahta R, Pusztai L, Claret FX. Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer. Clin Cancer Res. 2003 Nov 15; 9(15):5652-9. PMID: 14654548.
      Citations: 26     Fields:    Translation:Humans
    57. Kouvaraki MA, Rassidakis GZ, Tian L, Kumar R, Kittas C, Claret FX. Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1). Cancer Res. 2003 Jun 01; 63(11):2977-81. PMID: 12782606.
      Citations: 47     Fields:    Translation:HumansCells
    58. Le XF, Claret FX, Lammayot A, Tian L, Deshpande D, LaPushin R, Tari AM, Bast RC. The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition. J Biol Chem. 2003 Jun 27; 278(26):23441-50. PMID: 12700233.
      Citations: 61     Fields:    Translation:HumansCells
    59. Mansouri A, Ridgway LD, Korapati AL, Zhang Q, Tian L, Wang Y, Siddik ZH, Mills GB, Claret FX. Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells. J Biol Chem. 2003 May 23; 278(21):19245-56. PMID: 12637505.
      Citations: 129     Fields:    Translation:HumansCells
    60. Rassidakis GZ, Claret FX, Lai R, Zhang Q, Sarris AH, McDonnell TJ, Medeiros LJ. Expression of p27(Kip1) and c-Jun activation binding protein 1 are inversely correlated in systemic anaplastic large cell lymphoma. Clin Cancer Res. 2003 Mar; 9(3):1121-8. PMID: 12631617.
      Citations: 23     Fields:    Translation:HumansCells
    61. Pyle ME, Korbonits M, Gueorguiev M, Jordan S, Kola B, Morris DG, Meinhardt A, Powell MP, Claret FX, Zhang Q, Metz C, Bucala R, Grossman AB. Macrophage migration inhibitory factor expression is increased in pituitary adenoma cell nuclei. J Endocrinol. 2003 Jan; 176(1):103-10. PMID: 12525254.
      Citations: 11     Fields:    Translation:HumansCells
    62. Mansouri A, Zhang Q, Ridgway LD, Tian L, Claret FX. Cisplatin resistance in an ovarian carcinoma is associated with a defect in programmed cell death control through XIAP regulation. Oncol Res. 2003; 13(6-10):399-404. PMID: 12725530; PMCID: PMC4089892.
      Citations: 31     Fields:    Translation:HumansCells
    63. Chahal HS, Kaltsas G, Jordan S, Urmanova Y, Khalimova Z, Harris PE, Farrell WE, Claret FX, Grossman AB, Korbonits M. Expression of phosphorylated p27(Kip1) protein and Jun activation domain-binding protein 1 in human pituitary tumors. J Clin Endocrinol Metab. 2002 Jun; 87(6):2635-43. PMID: 12050228.
      Citations: 32     Fields:    Translation:HumansCells
    64. Mansouri A, Ridgway LD, Zhang Q, Claret FX. Activation of the JNK/SAPK and P38 Mitogen-Activated Protein Kinase Signaling Pathways Sensitize Tumor Cells to Cisplatin-Induced Apoptosis. ScientificWorldJournal. 2001; 1:35. PMID: 30147474; PMCID: PMC6084552.
      Citations: 1     Fields:    
    65. Aytac U, Claret FX, Ho L, Sato K, Ohnuma K, Mills GB, Cabanillas F, Morimoto C, Dang NH. Expression of CD26 and its associated dipeptidyl peptidase IV enzyme activity enhances sensitivity to doxorubicin-induced cell cycle arrest at the G(2)/M checkpoint. Cancer Res. 2001 Oct 01; 61(19):7204-10. PMID: 11585756.
      Citations: 9     Fields:    Translation:HumansCells
    66. Deng L, Lin-Lee YC, Claret FX, Kuo MT. 2-acetylaminofluorene up-regulates rat mdr1b expression through generating reactive oxygen species that activate NF-kappa B pathway. J Biol Chem. 2001 Jan 05; 276(1):413-20. PMID: 11020383.
      Citations: 24     Fields:    Translation:AnimalsCells
    67. Lee HY, Sueoka N, Hong WK, Mangelsdorf DJ, Claret FX, Kurie JM. All-trans-retinoic acid inhibits Jun N-terminal kinase by increasing dual-specificity phosphatase activity. Mol Cell Biol. 1999 Mar; 19(3):1973-80. PMID: 10022884; PMCID: PMC83990.
      Citations: 25     Fields:    Translation:HumansCells
    68. Le-Niculescu H, Bonfoco E, Kasuya Y, Claret FX, Green DR, Karin M. Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death. Mol Cell Biol. 1999 Jan; 19(1):751-63. PMID: 9858598; PMCID: PMC83932.
      Citations: 110     Fields:    Translation:AnimalsCells
    69. Herdegen T, Claret FX, Kallunki T, Martin-Villalba A, Winter C, Hunter T, Karin M. Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury. J Neurosci. 1998 Jul 15; 18(14):5124-35. PMID: 9651196; PMCID: PMC6793486.
      Citations: 71     Fields:    Translation:AnimalsCells
    70. Lee HY, Dawson MI, Claret FX, Chen JD, Walsh GL, Hong WK, Kurie JM. Evidence of a retinoid signaling alteration involving the activator protein 1 complex in tumorigenic human bronchial epithelial cells and non-small cell lung cancer cells. Cell Growth Differ. 1997 Mar; 8(3):283-91. PMID: 9056670.
      Citations: 4     Fields:    Translation:HumansCells
    71. Claret FX, Hibi M, Dhut S, Toda T, Karin M. A new group of conserved coactivators that increase the specificity of AP-1 transcription factors. Nature. 1996 Oct 03; 383(6599):453-7. PMID: 8837781.
      Citations: 132     Fields:    Translation:HumansAnimalsCells
    72. Cavigelli M, Dolfi F, Claret FX, Karin M. Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation. EMBO J. 1995 Dec 01; 14(23):5957-64. PMID: 8846788; PMCID: PMC394715.
      Citations: 152     Fields:    Translation:HumansCells
    73. Minden A, Lin A, Claret FX, Abo A, Karin M. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell. 1995 Jun 30; 81(7):1147-57. PMID: 7600582.
      Citations: 401     Fields:    Translation:HumansAnimalsCells
    74. Lin A, Minden A, Martinetto H, Claret FX, Lange-Carter C, Mercurio F, Johnson GL, Karin M. Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. Science. 1995 Apr 14; 268(5208):286-90. PMID: 7716521.
      Citations: 207     Fields:    Translation:HumansAnimalsCells
    75. Arias J, Alberts AS, Brindle P, Claret FX, Smeal T, Karin M, Feramisco J, Montminy M. Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature. 1994 Jul 21; 370(6486):226-9. PMID: 8028671.
      Citations: 196     Fields:    Translation:HumansAnimalsCells
    76. Claret FX, Chapel S, Garcés J, Tsai-Pflugfelder M, Bertholet C, Shapiro DJ, Wittek R, Wahli W, Claret FX, Garc?s J. Two functional forms of the Xenopus laevis estrogen receptor translated from a single mRNA species. J Biol Chem. 1994 May 13; 269(19):14047-55. PMID: 8188685.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    77. Schild C, Claret FX, Wahli W, Wolffe AP. A nucleosome-dependent static loop potentiates estrogen-regulated transcription from the Xenopus vitellogenin B1 promoter in vitro. EMBO J. 1993 Feb; 12(2):423-33. PMID: 8440235; PMCID: PMC413225.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    78. Corthésy B, Claret FX, Wahli W, Corth?sy B. Estrogen receptor level determines sex-specific in vitro transcription from the Xenopus vitellogenin promoter. Proc Natl Acad Sci U S A. 1990 Oct; 87(20):7878-82. PMID: 2236004; PMCID: PMC54854.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    79. Corthésy B, Cardinaux JR, Claret FX, Wahli W, Corth?sy B. A nuclear factor I-like activity and a liver-specific repressor govern estrogen-regulated in vitro transcription from the Xenopus laevis vitellogenin B1 promoter. Mol Cell Biol. 1989 Dec; 9(12):5548-62. PMID: 2586526; PMCID: PMC363725.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    80. Claret FX, Wahli W, ten Heggler-Bordier B. Immuno-electron microscopic identification of human estrogen receptor-DNA complexes at the estrogen-responsive element and in the first intron of a Xenopus vitellogenin gene. J Mol Biol. 1988 Nov 05; 204(1):217-20. PMID: 3216393.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    81. Trastuzumab. Frontiers in Oncology. 2 JUN.
    82. Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1. Proceedings of the National Academy of Sciences of the United States of America. 110:1273-1278.
    83. Synthesis of (1RS,2RS,5SR)-3,4,6,7-tetramethylidene-8-oxobicyclo[3.2.1]-oct-2-yl acetate and the chemo- and stereoselective coordination of its butadiene functions with rhodium and iron moieties. Organometallics. 9:2785-2792.
    84. RBM24 suppresses cancer progression by upregulating MIR-25 to target MALAT1 in nasopharyngeal carcinoma. Cell Death and Disease. 7.
    85. Constitutive control of AKT1 gene expression by JUNB/CJUN in ALK+ anaplastic large-cell lymphoma. Leukemia. 29:2162-2172.
    86. Novel biomarkers of nasopharyngeal carcinoma metastasis risk identified by reverse phase protein array based tumor profiling with consideration of plasma Epstein-Barr virus DNA load. Proteomics - Clinical Applications.
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