SEAN M. POST

TitleAssistant Professor
InstitutionMD Anderson
DepartmentLeukemia
Address1400 Holcombe Blvd
Houston TX 77030-4008
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ruvolo PP, Ma H, Ruvolo VR, Zhang X, Post SM, Andreeff M. LGALS1 acts as a pro-survival molecule in AML. Biochim Biophys Acta Mol Cell Res. 2020 Oct; 1867(10):118785. PMID: 32590026.
      Citations:    Fields:    
    2. Gallardo M, Malaney P, Aitken MJL, Zhang X, Link TM, Shah V, Alybayev S, Wu MH, Pageon LR, Ma H, Jacamo R, Yu L, Xu-Monette ZY, Steinman H, Lee HJ, Sarbassov D, Rapado I, Barton MC, Martinez-Lopez J, Bueso-Ramos C, Young KH, Post SM. Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas. J Natl Cancer Inst. 2020 01 01; 112(1):95-106. PMID: 31077320.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    3. Aitken MJL, Lee HJ, Post SM. Emerging treatment options for patients with p53-pathway-deficient CLL. Ther Adv Hematol. 2019; 10:2040620719891356. PMID: 31839919.
      Citations:    
    4. Manshouri T, Verstovsek S, Harris DM, Veletic I, Zhang X, Post SM, Bueso-Ramos CE, Estrov Z. Primary myelofibrosis marrow-derived CD14+/CD34- monocytes induce myelofibrosis-like phenotype in immunodeficient mice and give rise to megakaryocytes. PLoS One. 2019; 14(9):e0222912. PMID: 31569199.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    5. Hoff FW, Hu CW, Qutub AA, Qiu Y, Hornbaker MJ, Bueso-Ramos C, Abbas HA, Post SM, de Bont ESJM, Kornblau SM. Proteomic Profiling of Acute Promyelocytic Leukemia Identifies Two Protein Signatures Associated with Relapse. Proteomics Clin Appl. 2019 07; 13(4):e1800133. PMID: 30650251.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    6. Ohanian M, Rozovski U, Kanagal-Shamanna R, Abruzzo LV, Loghavi S, Kadia T, Futreal A, Bhalla K, Zuo Z, Huh YO, Post SM, Ruvolo P, Garcia-Manero G, Andreeff M, Kornblau S, Borthakur G, Hu P, Medeiros LJ, Takahashi K, Hornbaker MJ, Zhang J, Nogueras-González GM, Huang X, Verstovsek S, Estrov Z, Pierce S, Ravandi F, Kantarjian HM, Bueso-Ramos CE, Cortes JE. MYC protein expression is an important prognostic factor in acute myeloid leukemia. Leuk Lymphoma. 2019 01; 60(1):37-48. PMID: 29741984.
      Citations: 4     Fields:    Translation:Humans
    7. Ruvolo PP, Ruvolo VR, Burks JK, Qiu Y, Wang RY, Shpall EJ, Mirandola L, Hail N, Zeng Z, McQueen T, Daver N, Post SM, Chiriva-Internati M, Kornblau SM, Andreeff M. Role of MSC-derived galectin 3 in the AML microenvironment. Biochim Biophys Acta Mol Cell Res. 2018 07; 1865(7):959-969. PMID: 29655803.
      Citations: 1     Fields:    Translation:HumansCells
    8. Post SM, Kornblau SM, Quintás-Cardama A. p53 pathway dysfunction in AML: beyond TP53 mutations. Oncotarget. 2017 Dec 12; 8(65):108288-108289. PMID: 29312530.
      Citations: 2     Fields:    
    9. Ruvolo PP, Ma H, Ruvolo VR, Zhang X, Mu H, Schober W, Hernandez I, Gallardo M, Khoury JD, Cortes J, Andreeff M, Post SM. Anexelekto/MER tyrosine kinase inhibitor ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells by diverse mechanisms. Haematologica. 2017 12; 102(12):2048-2057. PMID: 28912176.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    10. Mirandola L, Pedretti E, Figueroa JA, Chiaramonte R, Colombo M, Chapman C, Grizzi F, Patrinicola F, Kast WM, Nguyen DD, Rahman RL, Daver N, Ruvolo P, Post SM, Bresalier RS, Chiriva-Internati M. Cancer testis antigen Sperm Protein 17 as a new target for triple negative breast cancer immunotherapy. Oncotarget. 2017 Sep 26; 8(43):74378-74390. PMID: 29088794.
      Citations: 5     Fields:    
    11. Post SM. One size doesn't fit all in Ph-like ALL. Blood. 2017 01 12; 129(2):140-141. PMID: 28082291.
      Citations:    Fields:    
    12. Verstovsek S, Manshouri T, Pilling D, Bueso-Ramos CE, Newberry KJ, Prijic S, Knez L, Bozinovic K, Harris DM, Spaeth EL, Post SM, Multani AS, Rampal RK, Ahn J, Levine RL, Creighton CJ, Kantarjian HM, Estrov Z. Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis. J Exp Med. 2016 08 22; 213(9):1723-40. PMID: 27481130.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    13. Gallardo M, Hornbaker MJ, Zhang X, Hu P, Bueso-Ramos C, Post SM. Aberrant hnRNP K expression: All roads lead to cancer. . 2016 Jun 17; 15(12):1552-7. PMID: 27049467.
      Citations:    
    14. Gallardo M, Lee HJ, Zhang X, Bueso-Ramos C, Pageon LR, McArthur M, Multani A, Nazha A, Manshouri T, Parker-Thornburg J, Rapado I, Quintas-Cardama A, Kornblau SM, Martinez-Lopez J, Post SM. hnRNP K Is a Haploinsufficient Tumor Suppressor that Regulates Proliferation and Differentiation Programs in Hematologic Malignancies. Cancer Cell. 2015 Oct 12; 28(4):486-499. PMID: 26412324.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    15. Zhang X, Pageon L, Post SM. Impact of the Mdm2(SNP309-G) allele on a murine model of colorectal cancer. Oncogene. 2015 Aug 13; 34(33):4412-20. PMID: 25435368.
      Citations: 4     Fields:    Translation:AnimalsCells
    16. Chen J, Shin JH, Zhao R, Phan L, Wang H, Xue Y, Post SM, Ho Choi H, Chen JS, Wang E, Zhou Z, Tseng C, Gully C, Velazquez-Torres G, Fuentes-Mattei E, Yeung G, Qiao Y, Chou PC, Su CH, Hsieh YC, Hsu SL, Ohshiro K, Shaikenov T, Wang H, Yeung SC, Lee MH. CSN6 drives carcinogenesis by positively regulating Myc stability. Nat Commun. 2014 Nov 14; 5:5384. PMID: 25395170.
      Citations: 22     Fields:    Translation:AnimalsCells
    17. Jiang S, Minter LC, Stratton SA, Yang P, Abbas HA, Akdemir ZC, Pant V, Post S, Gagea M, Lee RG, Lozano G, Barton MC. TRIM24 suppresses development of spontaneous hepatic lipid accumulation and hepatocellular carcinoma in mice. J Hepatol. 2015 Feb; 62(2):371-9. PMID: 25281858.
      Citations: 17     Fields:    Translation:HumansAnimals
    18. Quintás-Cardama A, Zhang N, Qiu YH, Post S, Creighton CJ, Cortes J, Coombes KR, Kornblau SM. Loss of TRIM62 expression is an independent adverse prognostic factor in acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2015 Feb; 15(2):115-127.e15. PMID: 25248926.
      Citations: 12     Fields:    Translation:Humans
    19. Quintás-Cardama A, Post SM, Solis LM, Xiong S, Yang P, Chen N, Wistuba II, Killary AM, Lozano G. Loss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancer. J Pathol. 2014 Sep; 234(1):108-19. PMID: 24890125.
      Citations: 8     Fields:    Translation:HumansAnimals
    20. Pant V, Xiong S, Jackson JG, Post SM, Abbas HA, Quintás-Cardama A, Hamir AN, Lozano G. The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity. Genes Dev. 2013 Sep 01; 27(17):1857-67. PMID: 23973961.
      Citations: 39     Fields:    Translation:AnimalsCells
    21. Post SM. Mouse models of sarcomas: critical tools in our understanding of the pathobiology. Clin Sarcoma Res. 2012 Oct 04; 2(1):20. PMID: 23036318.
      Citations:    
    22. Quintás-Cardama A, Qiu YH, Post SM, Zhang Y, Creighton CJ, Cortes J, Kornblau SM. Reverse phase protein array profiling reveals distinct proteomic signatures associated with chronic myeloid leukemia progression and with chronic phase in the CD34-positive compartment. Cancer. 2012 Nov 01; 118(21):5283-92. PMID: 22517119.
      Citations: 8     Fields:    Translation:HumansCells
    23. Suh YA, Post SM, Elizondo-Fraire AC, Maccio DR, Jackson JG, El-Naggar AK, Van Pelt C, Terzian T, Lozano G. Multiple stress signals activate mutant p53 in vivo. Cancer Res. 2011 Dec 01; 71(23):7168-75. PMID: 21983037.
      Citations: 47     Fields:    Translation:AnimalsCells
    24. Jackson JG, Post SM, Lozano G. Regulation of tissue- and stimulus-specific cell fate decisions by p53 in vivo. J Pathol. 2011 Jan; 223(2):127-36. PMID: 20957626.
      Citations: 26     Fields:    Translation:HumansAnimalsPHPublic Health
    25. Post SM, Lozano G. You can win by losing: p53 mutations in rhabdomyosarcomas. J Pathol. 2010 Oct; 222(2):124-8. PMID: 20821751.
      Citations: 2     Fields:    Translation:HumansAnimals
    26. Post SM, Quintás-Cardama A, Pant V, Iwakuma T, Hamir A, Jackson JG, Maccio DR, Bond GL, Johnson DG, Levine AJ, Lozano G. A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development. Cancer Cell. 2010 Sep 14; 18(3):220-30. PMID: 20832750.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    27. Xiong S, Pant V, Suh YA, Van Pelt CS, Wang Y, Valentin-Vega YA, Post SM, Lozano G. Spontaneous tumorigenesis in mice overexpressing the p53-negative regulator Mdm4. Cancer Res. 2010 Sep 15; 70(18):7148-54. PMID: 20736370.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    28. Post SM, Pant V, Abbas H, Quintás-Cardama A. Prognostic impact of the MDM2SNP309 allele in leukemia and lymphoma. Oncotarget. 2010 Jul; 1(3):168-74. PMID: 21301048.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    29. Fang S, Krahe R, Lozano G, Han Y, Chen W, Post SM, Zhang B, Wilson CD, Bachinski LL, Strong LC, Amos CI. Effects of MDM2, MDM4 and TP53 codon 72 polymorphisms on cancer risk in a cohort study of carriers of TP53 germline mutations. PLoS One. 2010 May 26; 5(5):e10813. PMID: 20520810.
      Citations: 16     Fields:    Translation:Humans
    30. Post SM, Quintás-Cardama A. Closing in on the pathogenesis of the 5q- syndrome. Expert Rev Anticancer Ther. 2010 May; 10(5):655-8. PMID: 20469997.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    31. Post SM, Quintás-Cardama A, Terzian T, Smith C, Eischen CM, Lozano G. p53-dependent senescence delays Emu-myc-induced B-cell lymphomagenesis. Oncogene. 2010 Mar 04; 29(9):1260-9. PMID: 19935700.
      Citations: 33     Fields:    Translation:AnimalsCells
    32. Martinez LA, Goluszko E, Chen HZ, Leone G, Post S, Lozano G, Chen Z, Chauchereau A. E2F3 is a mediator of DNA damage-induced apoptosis. Mol Cell Biol. 2010 Jan; 30(2):524-36. PMID: 19917728.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    33. Terzian T, Suh YA, Iwakuma T, Post SM, Neumann M, Lang GA, Van Pelt CS, Lozano G. The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss. Genes Dev. 2008 May 15; 22(10):1337-44. PMID: 18483220.
      Citations: 158     Fields:    Translation:AnimalsCells
    34. Song W, Levin DS, Varkey J, Post S, Bermudez VP, Hurwitz J, Tomkinson AE. A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes. J Biol Chem. 2007 Aug 03; 282(31):22721-30. PMID: 17561505.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    35. Motycka TA, Bessho T, Post SM, Sung P, Tomkinson AE. Physical and functional interaction between the XPF/ERCC1 endonuclease and hRad52. J Biol Chem. 2004 Apr 02; 279(14):13634-9. PMID: 14734547.
      Citations: 32     Fields:    Translation:HumansCells
    36. Post SM, Lee EY. Detection of kinase and phosphatase activities. Methods Mol Biol. 2004; 241:285-97. PMID: 14970662.
      Citations:    Fields:    Translation:HumansAnimalsCells
    37. Post SM, Tomkinson AE, Lee EY. The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon. Nucleic Acids Res. 2003 Oct 01; 31(19):5568-75. PMID: 14500819.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    38. Post S, Weng YC, Cimprich K, Chen LB, Xu Y, Lee EY. Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage. Proc Natl Acad Sci U S A. 2001 Nov 06; 98(23):13102-7. PMID: 11687627.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    39. Post SM, de Roos B, Vermeulen M, Afman L, Jong MC, Dahlmans VE, Havekes LM, Stellaard F, Katan MB, Princen HM. Cafestol increases serum cholesterol levels in apolipoprotein E*3-Leiden transgenic mice by suppression of bile acid synthesis. Arterioscler Thromb Vasc Biol. 2000 Jun; 20(6):1551-6. PMID: 10845871.
      Citations: 4     Fields:    Translation:Animals
    40. Biology of Adult Myelocytic Leukemia and Myelodysplasia. 421-432.
    41. Germline variation in TP53 regulatory network genes associates with breast cancer survival and treatment outcome. Breast Diseases. 24:243-245.
    42. Aberrant hnRNP K expression. Cell Cycle. 15:1552-1557.
    43. p53 pathway dysfunction is highly prevalent in acute myeloid leukemia independent of TP53 mutational status. Leukemia.
    44. Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis. Journal of Experimental Medicine. 213:1723-1740.
    45. HnRNP K Is a Haploinsufficient Tumor Suppressor that Regulates Proliferation and Differentiation Programs in Hematologic Malignancies. Cancer Cell. 28:486-499.
    46. Effects of MDM2, MDM4and TP53 codon 72 polymorphisms on cancer risk in a cohort study of carriers of TP53 germline mutations. PLoS One. 5.
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