JAMES P ALLISON to Lymphocyte Activation
This is a "connection" page, showing publications JAMES P ALLISON has written about Lymphocyte Activation.
Connection Strength
4.391
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Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States. Immunity. 2019 04 16; 50(4):1084-1098.e10.
Score: 0.458
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Pillars article: CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. The journal of experimental medicine. 1995. 182: 459-465. J Immunol. 2011 Oct 01; 187(7):3459-65.
Score: 0.273
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Strength of TCR-peptide/MHC interactions and in vivo T cell responses. J Immunol. 2011 May 01; 186(9):5039-45.
Score: 0.265
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Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS). Curr Opin Immunol. 2010 Jun; 22(3):326-32.
Score: 0.243
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Negative regulators of T-cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections. Immunol Rev. 2009 May; 229(1):67-87.
Score: 0.231
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The B7 family and cancer therapy: costimulation and coinhibition. Clin Cancer Res. 2007 Sep 15; 13(18 Pt 1):5271-9.
Score: 0.206
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To be or not to be B7. J Clin Invest. 2006 Oct; 116(10):2590-3.
Score: 0.193
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MHC class II-independent and -dependent T cell expansion and B cell hyperactivity in vivo in mice deficient in CD152 (CTLA-4). Int Immunol. 2004 Jul; 16(7):895-904.
Score: 0.163
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B7x: a widely expressed B7 family member that inhibits T cell activation. Proc Natl Acad Sci U S A. 2003 Sep 02; 100(18):10388-92.
Score: 0.155
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The lymphoproliferative defect in CTLA-4-deficient mice is ameliorated by an inhibitory NK cell receptor. Blood. 2002 Jun 15; 99(12):4509-16.
Score: 0.143
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Fundamental Mechanisms of Immune Checkpoint Blockade Therapy. Cancer Discov. 2018 09; 8(9):1069-1086.
Score: 0.110
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Co-stimulation in T cell responses. Curr Opin Immunol. 1997 Jun; 9(3):396-404.
Score: 0.101
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Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity. Nat Commun. 2017 02 13; 8:14340.
Score: 0.099
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Manipulation of costimulatory signals to enhance antitumor T-cell responses. Curr Opin Immunol. 1995 Oct; 7(5):682-6.
Score: 0.090
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Checkpoints. Cell. 2015 Sep 10; 162(6):1202-5.
Score: 0.090
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T-cell activation: integration of signals from the antigen receptor and costimulatory molecules. Immunol Today. 1995 Jul; 16(7):306-10.
Score: 0.088
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The future of immune checkpoint therapy. Science. 2015 Apr 03; 348(6230):56-61.
Score: 0.087
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Friends not foes: CTLA-4 blockade and mTOR inhibition cooperate during CD8+ T cell priming to promote memory formation and metabolic readiness. J Immunol. 2015 Mar 01; 194(5):2089-98.
Score: 0.086
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CD28-B7 interactions in T-cell activation. Curr Opin Immunol. 1994 Jun; 6(3):414-9.
Score: 0.082
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Increased frequency of ICOS+ CD4 T cells as a pharmacodynamic biomarker for anti-CTLA-4 therapy. Cancer Immunol Res. 2013 Oct; 1(4):229-34.
Score: 0.077
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Cutting edge: CTLA-4 on effector T cells inhibits in trans. J Immunol. 2012 Aug 01; 189(3):1123-7.
Score: 0.072
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CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature. 1992 Apr 16; 356(6370):607-9.
Score: 0.071
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Attenuated T cell responses to a high-potency ligand in vivo. PLoS Biol. 2010 Sep 14; 8(9).
Score: 0.063
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TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo. J Exp Med. 2010 Aug 02; 207(8):1701-11.
Score: 0.063
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Cancer immunotherapy: co-stimulatory agonists and co-inhibitory antagonists. Clin Exp Immunol. 2009 Jul; 157(1):9-19.
Score: 0.057
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CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion. Blood. 2008 Aug 15; 112(4):1175-83.
Score: 0.054
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A genetic library screen for signaling proteins that interact with phosphorylated T cell costimulatory receptors. Genomics. 2006 Dec; 88(6):841-845.
Score: 0.048
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CTLA-4 overexpression inhibits T cell responses through a CD28-B7-dependent mechanism. J Immunol. 2006 Jul 15; 177(2):1052-61.
Score: 0.048
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Engagement of NKG2D by cognate ligand or antibody alone is insufficient to mediate costimulation of human and mouse CD8+ T cells. J Immunol. 2005 Feb 15; 174(4):1922-31.
Score: 0.043
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B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse. Immunity. 2004 Sep; 21(3):401-13.
Score: 0.042
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BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. Nat Immunol. 2003 Jul; 4(7):670-9.
Score: 0.038
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CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nat Immunol. 2002 Jul; 3(7):611-8.
Score: 0.036
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Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength. Immunity. 2002 Jan; 16(1):23-35.
Score: 0.035
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Pre-existing immune status associated with response to combination of sipuleucel-T and ipilimumab in patients with metastatic castration-resistant prostate cancer. J Immunother Cancer. 2021 05; 9(5).
Score: 0.033
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Comprehensive T cell repertoire characterization of non-small cell lung cancer. Nat Commun. 2020 01 30; 11(1):603.
Score: 0.030
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Mechanisms of Resistance to Immune Checkpoint Blockade: Why Does Checkpoint Inhibitor Immunotherapy Not Work for All Patients? Am Soc Clin Oncol Educ Book. 2019 Jan; 39:147-164.
Score: 0.029
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Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer. Proc Natl Acad Sci U S A. 2019 01 29; 116(5):1692-1697.
Score: 0.028
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Itk negatively regulates induction of T cell proliferation by CD28 costimulation. J Exp Med. 1997 Jul 21; 186(2):221-8.
Score: 0.026
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Concurrent OX40 and CD30 Ligand Blockade Abrogates the CD4-Driven Autoimmunity Associated with CTLA4 and PD1 Blockade while Preserving Excellent Anti-CD8 Tumor Immunity. J Immunol. 2017 08 01; 199(3):974-981.
Score: 0.025
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T cell-mediated elimination of B7.2 transgenic B cells. Immunity. 1997 Mar; 6(3):327-39.
Score: 0.025
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Metastatic Melanoma Patient Had a Complete Response with Clonal Expansion after Whole Brain Radiation and PD-1 Blockade. Cancer Immunol Res. 2017 02; 5(2):100-105.
Score: 0.025
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Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity. Nat Commun. 2016 08 30; 7:12632.
Score: 0.024
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ICOS Promotes the Function of CD4+ Effector T Cells during Anti-OX40-Mediated Tumor Rejection. Cancer Res. 2016 07 01; 76(13):3684-9.
Score: 0.023
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Strategies for combining immunotherapy with radiation for anticancer therapy. Immunotherapy. 2015; 7(9):967-980.
Score: 0.022
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Co-stimulation via CD28 induces activation of a refractory subset of MRL-lpr/lpr T lymphocytes. Int Immunol. 1993 Nov; 5(11):1451-60.
Score: 0.020
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Activation and differentiation requirements of primary T cells in vitro. Proc Natl Acad Sci U S A. 1993 Oct 01; 90(19):8987-91.
Score: 0.020
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Enhancement of tumor-reactive cytotoxic CD4+ T cell responses after ipilimumab treatment in four advanced melanoma patients. Cancer Immunol Res. 2013 Oct; 1(4):235-44.
Score: 0.020
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CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help. J Exp Med. 1993 Jun 01; 177(6):1791-6.
Score: 0.019
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T cell receptor-triggered activation of intraepithelial lymphocytes in vitro. Int Immunol. 1993 Feb; 5(2):145-53.
Score: 0.019
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Augmented IL-15Ra expression by CD40 activation is critical in synergistic CD8 T cell-mediated antitumor activity of anti-CD40 antibody with IL-15 in TRAMP-C2 tumors in mice. J Immunol. 2012 Jun 15; 188(12):6156-64.
Score: 0.018
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CTLA-4 blockade increases antigen-specific CD8(+) T cells in prevaccinated patients with melanoma: three cases. Cancer Immunol Immunother. 2011 Aug; 60(8):1137-46.
Score: 0.016
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Two distinct mechanisms of augmented antitumor activity by modulation of immunostimulatory/inhibitory signals. Clin Cancer Res. 2010 May 15; 16(10):2781-91.
Score: 0.015
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Structure, function, and serology of the T-cell antigen receptor complex. Annu Rev Immunol. 1987; 5:503-40.
Score: 0.012
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B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions [corrections]. J Immunol. 2004 Jan 01; 172(1):34-9.
Score: 0.010
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Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci U S A. 2003 Jul 08; 100(14):8372-7.
Score: 0.010
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Cutting edge: a crucial role for B7-CD28 in transmitting T help from APC to CTL. J Immunol. 2002 Oct 15; 169(8):4094-7.
Score: 0.009
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Human DR (Ia-like) antigens: biological and molecular profile. Contemp Top Mol Immunol. 1978; 7:239-81.
Score: 0.002