Keywords
Last Name
Institution

TODD ROSENGART

TitleChair
InstitutionBaylor College of Medicine
DepartmentDepartment of Surgery
Address6501 Fannin, Suite NC114
Houston TX 77030
vCardDownload vCard
    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Surgery
    DivisionSurgery


    Collapse Additional Tools and Researcher Information 
    Collapse Faculty Mentor
    Collapse Verify Publications

    Collapse Overview 
    Collapse overview
    Dr. Rosengart is an NIH-supported scientist with uninterrupted extramural funding since 1998.
    An extensively published investigator, he was recently named editor of Seminars in Thoracic and Cardiovascular Surgery and appointed member of the NIH Bioengineering, Technology, and Surgical Sciences (BTSS) study section.

    He was one of the pioneers in the field of gene therapy, with work beginning in the early 1990s, and is now leading a team of scientists engaged in the study of cardiac cellular reprogramming.
    He also holds nearly a dozen patents, including those for a method of inducing angiogenesis, a remote sensing gene therapy delivery device, and an apparatus for creating anastomoses.

    Collapse keywords
    • Gene therapy
    • Cellular reprogramming
    • Angiogenesis


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Whellan DJ, McCarey MM, Taylor BS, Rosengart TK, Wallace AS, Shroyer AL, Gammie JS, Peterson ED. Trends in Robotic-Assisted Coronary Artery Bypass Grafts: A Study of The Society of Thoracic Surgeons Adult Cardiac Surgery Database, 2006 to 2012. Ann Thorac Surg. 2016 Jul; 102(1):140-6. PMID: 27016838.
      View in: PubMed
    2. Coselli JS, LeMaire SA, Preventza O, de la Cruz KI, Cooley DA, Price MD, Stolz AP, Green SY, Arredondo CN, Rosengart TK. Outcomes of 3309 thoracoabdominal aortic aneurysm repairs. J Thorac Cardiovasc Surg. 2016 May; 151(5):1323-38. PMID: 26898979.
      View in: PubMed
    3. Rosengart TK, Austin EH, Pass HI, Weisel RD. Introduction: Great Institutions in Cardiothoracic Surgery. Semin Thorac Cardiovasc Surg. 2015; 27(4):339-40. PMID: 26811039.
      View in: PubMed
    4. Aldea GS, Bakaeen FG, Pal J, Fremes S, Head SJ, Sabik J, Rosengart T, Kappetein AP, Thourani VH, Firestone S, Mitchell JD. The Society of Thoracic Surgeons Clinical Practice Guidelines on Arterial Conduits for Coronary Artery Bypass Grafting. Ann Thorac Surg. 2016 Feb; 101(2):801-9. PMID: 26680310.
      View in: PubMed
    5. Preventza O, Garcia A, Cooley DA, Haywood-Watson RJ, Simpson K, Bakaeen FG, Cornwell LD, Omer S, de la Cruz KI, Price MD, Rosengart TK, LeMaire SA, Coselli JS. Total aortic arch replacement: A comparative study of zone 0 hybrid arch exclusion versus traditional open repair. J Thorac Cardiovasc Surg. 2015 Dec; 150(6):1591-8; discussion 1598-600. PMID: 26573355.
      View in: PubMed
    6. Pocock E, Tsai PI, Markan S, Weldon SA, Rosengart TK. Classic resectional technique for mitral valve repair: triangular resection via right anterior thoracotomy. Ann Cardiothorac Surg. 2015 Sep; 4(5):476-7. PMID: 26539355.
      View in: PubMed
    7. Rosengart TK. Thankfully, back to basics. J Thorac Cardiovasc Surg. 2015 Nov; 150(5):1278-9. PMID: 26349595.
      View in: PubMed
    8. Fourman MS, Gersch RP, Phillips BT, Nasser A, Rivara A, Verma R, Dagum AB, Rosengart TK, Bui DT. Comparison of Laser Doppler and Laser-Assisted Indocyanine Green Angiography Prediction of Flap Survival in a Novel Modification of the McFarlane Flap. Ann Plast Surg. 2015 Jul; 75(1):102-7. PMID: 24401807.
      View in: PubMed
    9. Preventza O, Price MD, Simpson KH, Cooley DA, Pocock E, de la Cruz KI, Green SY, LeMaire SA, Rosengart TK, Coselli JS. Hemiarch and Total Arch Surgery in Patients With Previous Repair of Acute Type I Aortic Dissection. Ann Thorac Surg. 2015 Sep; 100(3):833-8. PMID: 26116478.
      View in: PubMed
    10. Cornwell LD, Omer S, Rosengart T, Holman WL, Bakaeen FG. Changes over time in risk profiles of patients who undergo coronary artery bypass graft surgery: the Veterans Affairs Surgical Quality Improvement Program (VASQIP). JAMA Surg. 2015 Apr; 150(4):308-15. PMID: 25671647.
      View in: PubMed
    11. Liu L, Liu L, Leung LH, Cooney AJ, Chen C, Rosengart TK, Ma Y, Yang J. Knockdown of SALL4 Protein Enhances All-trans Retinoic Acid-induced Cellular Differentiation in Acute Myeloid Leukemia Cells. J Biol Chem. 2015 Apr 24; 290(17):10599-609. PMID: 25737450; PMCID: PMC4409227.
    12. Preventza O, Garcia A, Cooley DA, Tuluca A, Simpson KH, Bakaeen FG, Omer S, Cornwell L, Rosengart TK, Coselli JS. Reprint of: Reoperations on the total aortic arch in 119 patients: short- and mid-term outcomes, focusing on composite adverse outcomes and survival analysis. J Thorac Cardiovasc Surg. 2015 Feb; 149(2 Suppl):S59-64. PMID: 25726080.
      View in: PubMed
    13. Pass HI, Rosengart TK. Seminars in Thoracic and Cardiovascular Surgery. Introduction. Semin Thorac Cardiovasc Surg. 2014; 26(3):173. PMID: 25527008.
      View in: PubMed
    14. Preventza O, Simpson KH, Cooley DA, Cornwell L, Bakaeen FG, Omer S, Rodriguez V, de la Cruz KI, Rosengart T, Coselli JS. Unilateral versus bilateral cerebral perfusion for acute type A aortic dissection. Ann Thorac Surg. 2015 Jan; 99(1):80-7. PMID: 25442989.
      View in: PubMed
    15. Rosengart TK. Total arterial revascularization: when will its time come? J Thorac Cardiovasc Surg. 2014 Oct; 148(4):1244-5. PMID: 25260267.
      View in: PubMed
    16. Preventza O, Garcia A, Cooley DA, Tuluca A, Simpson KH, Bakaeen FG, Omer S, Cornwell L, Rosengart TK, Coselli JS. Reoperations on the total aortic arch in 119 patients: short- and mid-term outcomes, focusing on composite adverse outcomes and survival analysis. J Thorac Cardiovasc Surg. 2014 Dec; 148(6):2967-72. PMID: 25152482.
      View in: PubMed
    17. Rosengart TK. The 1000th VAD, the great rivalry, and the grand experiment of the Texas Medical Center. Semin Thorac Cardiovasc Surg. 2014; 26(1):1-3. PMID: 24952751.
      View in: PubMed
    18. Rosengart TK. The 1,000 th VAD, the great rivalry, and the grand experiment of the Texas Medical Center. Tex Heart Inst J. 2014 Apr; 41(2):112-4; discussion 114. PMID: 24808766; PMCID: PMC4004478.
    19. Mathison M, Singh VP, Gersch RP, Ramirez MO, Cooney A, Kaminsky SM, Chiuchiolo MJ, Nasser A, Yang J, Crystal RG, Rosengart TK. "Triplet" polycistronic vectors encoding Gata4, Mef2c, and Tbx5 enhances postinfarct ventricular functional improvement compared with singlet vectors. J Thorac Cardiovasc Surg. 2014 Oct; 148(4):1656-1664.e2. PMID: 24755332.
      View in: PubMed
    20. Dathatri S, Gruberg L, Anand J, Romeiser J, Sharma S, Finnin E, Shroyer AL, Rosengart TK. Informed consent for cardiac procedures: deficiencies in patient comprehension with current methods. Ann Thorac Surg. 2014 May; 97(5):1505-11; discussion 1511-2. PMID: 24629303.
      View in: PubMed
    21. Rosengart TK. The 1,000th VAD, the great rivalry, and the grand experiment of the Texas Medical Center. J Thorac Cardiovasc Surg. 2014 Jun; 147(6):1745-7; discussion 1747. PMID: 24837721.
      View in: PubMed
    22. Omer S, Cornwell LD, Rosengart TK, Kelly RF, Ward HB, Holman WL, Bakaeen FG. Completeness of coronary revascularization and survival: Impact of age and off-pump surgery. J Thorac Cardiovasc Surg. 2014 Oct; 148(4):1307-1315.e1. PMID: 24521971.
      View in: PubMed
    23. Bakaeen FG, Shroyer AL, Gammie JS, Sabik JF, Cornwell LD, Coselli JS, Rosengart TK, O'Brien SM, Wallace A, Shahian DM, Grover FL, Puskas JD. Trends in use of off-pump coronary artery bypass grafting: Results from the Society of Thoracic Surgeons Adult Cardiac Surgery Database. J Thorac Cardiovasc Surg. 2014 Sep; 148(3):856-3, 864.e1; discussion 863-4. PMID: 25043865.
      View in: PubMed
    24. Kaminsky SM, Rosengart TK, Rosenberg J, Chiuchiolo MJ, Van de Graaf B, Sondhi D, Crystal RG. Gene therapy to stimulate angiogenesis to treat diffuse coronary artery disease. Hum Gene Ther. 2013 Nov; 24(11):948-63. PMID: 24164242.
      View in: PubMed
    25. Liu L, Souto J, Liao W, Jiang Y, Li Y, Nishinakamura R, Huang S, Rosengart T, Yang VW, Schuster M, Ma Y, Yang J. Histone lysine-specific demethylase 1 (LSD1) protein is involved in Sal-like protein 4 (SALL4)-mediated transcriptional repression in hematopoietic stem cells. J Biol Chem. 2013 Nov 29; 288(48):34719-28. PMID: 24163373; PMCID: PMC3843083.
    26. Rosengart TK, Romeiser JL, White LJ, Fratello A, Fallon E, Senzel L, Shroyer AL. Platelet activity measured by a rapid turnaround assay identifies coronary artery bypass grafting patients at increased risk for bleeding and transfusion complications after clopidogrel administration. J Thorac Cardiovasc Surg. 2013 Nov; 146(5):1259-1266, 1266.e1; discussion 1266. PMID: 23953984.
      View in: PubMed
    27. Kaminsky SM, Quach L, Chen S, Pierre-Destine L, Van de Graaf B, Monette S, Rosenberg JB, De BP, Sondhi D, Hackett NR, Mezey JG, Rosengart TK, Crystal RG. Safety of direct cardiac administration of AdVEGF-All6A+, a replication-deficient adenovirus vector cDNA/genomic hybrid expressing all three major isoforms of human vascular endothelial growth factor, to the ischemic myocardium of rats. Hum Gene Ther Clin Dev. 2013 Mar; 24(1):38-46. PMID: 23692382.
      View in: PubMed
    28. Price JD, Romeiser JL, Gnerre JM, Shroyer AL, Rosengart TK. Risk analysis for readmission after coronary artery bypass surgery: developing a strategy to reduce readmissions. J Am Coll Surg. 2013 Mar; 216(3):412-9. PMID: 23313544.
      View in: PubMed
    29. Rosengart TK. Cardiac cellular reprogramming. Tex Heart Inst J. 2013; 40(5):581-2. PMID: 24391328; PMCID: PMC3853848.
    30. Pass H, Rosengart T. Welcome to the new seminars. Semin Thorac Cardiovasc Surg. 2013; 25(1):1. PMID: 23800521.
      View in: PubMed
    31. Rosengart TK, Bishawi MM, Halbreiner MS, Fakhoury M, Finnin E, Hollmann C, Shroyer AL, Crystal RG. Long-term follow-up assessment of a phase 1 trial of angiogenic gene therapy using direct intramyocardial administration of an adenoviral vector expressing the VEGF121 cDNA for the treatment of diffuse coronary artery disease. Hum Gene Ther. 2013 Feb; 24(2):203-8. PMID: 23137122; PMCID: PMC3581022.
    32. Mathison M, Gersch RP, Nasser A, Lilo S, Korman M, Fourman M, Hackett N, Shroyer K, Yang J, Ma Y, Crystal RG, Rosengart TK. In vivo cardiac cellular reprogramming efficacy is enhanced by angiogenic preconditioning of the infarcted myocardium with vascular endothelial growth factor. J Am Heart Assoc. 2012 Dec; 1(6):e005652. PMID: 23316332; PMCID: PMC3540681.
    33. Ferraris VA, Saha SP, Oestreich JH, Song HK, Rosengart T, Reece TB, Mazer CD, Bridges CR, Despotis GJ, Jointer K, Clough ER. 2012 update to the Society of Thoracic Surgeons guideline on use of antiplatelet drugs in patients having cardiac and noncardiac operations. Ann Thorac Surg. 2012 Nov; 94(5):1761-81. PMID: 23098967.
      View in: PubMed
    34. Rosengart TK, Fallon E, Crystal RG. Cardiac biointerventions: whatever happened to stem cell and gene therapy? Innovations (Phila). 2012 May-Jun; 7(3):173-9. PMID: 22885457.
      View in: PubMed
    35. Crystal RG, Kaminsky SM, Hackett NR, Rosengart TK. Double-blinded, placebo-controlled, randomized gene therapy using surgery for vector delivery. Hum Gene Ther. 2012 May; 23(5):438-41. PMID: 22452798.
      View in: PubMed
    36. Rosengart TK. Cognitive decline and ischemic microlesions after coronary catheterization: a comparison to coronary artery bypass. Am Heart J. 2012 Apr; 163(4):e13. PMID: 22520544.
      View in: PubMed
    37. Jeremias A, Kaul S, Rosengart TK, Gruberg L, Brown DL. The impact of revascularization on mortality in patients with nonacute coronary artery disease. Am J Med. 2009 Feb; 122(2):152-61. PMID: 19185092.
      View in: PubMed
    38. Sweet JJ, Finnin E, Wolfe PL, Beaumont JL, Hahn E, Marymont J, Sanborn T, Rosengart TK. Absence of cognitive decline one year after coronary bypass surgery: comparison to nonsurgical and healthy controls. Ann Thorac Surg. 2008 May; 85(5):1571-8. PMID: 18442540.
      View in: PubMed
    39. Rosengart TK, Feldman T, Borger MA, Vassiliades TA, Gillinov AM, Hoercher KJ, Vahanian A, Bonow RO, O'Neill W. Percutaneous and minimally invasive valve procedures: a scientific statement from the American Heart Association Council on Cardiovascular Surgery and Anesthesia, Council on Clinical Cardiology, Functional Genomics and Translational Biology Interdisciplinary Working Group, and Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2008 Apr 1; 117(13):1750-67. PMID: 18332270.
      View in: PubMed
    40. Rosengart TK. Invited commentary. Ann Thorac Surg. 2008 Jan; 85(1):64. PMID: 18154781.
      View in: PubMed
    41. Retuerto MA, Beckmann JT, Carbray J, Patejunas G, Sarateanu S, Kane BJ, Smulevitz B, McPherson DD, Rosengart TK. Angiogenic pretreatment to enhance myocardial function after cellular cardiomyoplasty with skeletal myoblasts. J Thorac Cardiovasc Surg. 2007 Feb; 133(2):478-484.e2. PMID: 17258586.
      View in: PubMed
    42. Rosengart TK, Sweet JJ, Finnin E, Wolfe P, Cashy J, Hahn E, Marymont J, Sanborn T. Stable cognition after coronary artery bypass grafting: comparisons with percutaneous intervention and normal controls. Ann Thorac Surg. 2006 Aug; 82(2):597-607. PMID: 16863771.
      View in: PubMed
    43. Sarateanu CS, Retuerto MA, Beckmann JT, McGregor L, Carbray J, Patejunas G, Nayak L, Milbrandt J, Rosengart TK. An Egr-1 master switch for arteriogenesis: studies in Egr-1 homozygous negative and wild-type animals. J Thorac Cardiovasc Surg. 2006 Jan; 131(1):138-45. PMID: 16399305.
      View in: PubMed
    44. Dang NC, Aboodi MS, Sakaguchi T, Wasserman HS, Argenziano M, Cosgrove DM, Rosengart TK, Feldman T, Block PC, Oz MC. Surgical revision after percutaneous mitral valve repair with a clip: initial multicenter experience. Ann Thorac Surg. 2005 Dec; 80(6):2338-42. PMID: 16305903.
      View in: PubMed
    45. Rosengart TK, Sweet J, Finnin EB, Wolfe P, Cashy J, Hahn E, Marymont J, Sanborn T. Neurocognitive functioning in patients undergoing coronary artery bypass graft surgery or percutaneous coronary intervention: evidence of impairment before intervention compared with normal controls. Ann Thorac Surg. 2005 Oct; 80(4):1327-34; discussion 1334-5. PMID: 16181864.
      View in: PubMed
    46. Amano H, Hackett NR, Kaner RJ, Whitlock P, Rosengart TK, Crystal RG. Alteration of splicing signals in a genomic/cDNA hybrid VEGF gene to modify the ratio of expressed VEGF isoforms enhances safety of angiogenic gene therapy. Mol Ther. 2005 Oct; 12(4):716-24. PMID: 16039163.
      View in: PubMed
    47. Rajamannan NM, Nealis TB, Subramaniam M, Pandya S, Stock SR, Ignatiev CI, Sebo TJ, Rosengart TK, Edwards WD, McCarthy PM, Bonow RO, Spelsberg TC. Calcified rheumatic valve neoangiogenesis is associated with vascular endothelial growth factor expression and osteoblast-like bone formation. Circulation. 2005 Jun 21; 111(24):3296-301. PMID: 15956138; PMCID: PMC3951870.
    48. Baumgartner WA, Burrows S, del Nido PJ, Gardner TJ, Goldberg S, Gorman RC, Letsou GV, Mascette A, Michler RE, Puskas JD, Rose EA, Rosengart TK, Sellke FW, Shumway SJ, Wilke N. Recommendations of the National Heart, Lung, and Blood Institute Working Group on Future Direction in Cardiac Surgery. Circulation. 2005 Jun 7; 111(22):3007-13. PMID: 15939834.
      View in: PubMed
    49. Rosengart TK, Chedrawy EG, Patejunas G, Retuarto M. Vascular endothelial growth factor before cells. J Thorac Cardiovasc Surg. 2005 Mar; 129(3):696. PMID: 15746767.
      View in: PubMed
    50. Nayak L, Rosengart TK. Gene therapy for heart failure. Semin Thorac Cardiovasc Surg. 2005; 17(4):343-7. PMID: 16428042.
      View in: PubMed
    51. Schalch P, Patejunas G, Retuerto M, Sarateanu S, Milbrandt J, Thakker G, Kim D, Carbray J, Crystal RG, Rosengart TK. Homozygous deletion of early growth response 1 gene and critical limb ischemia after vascular ligation in mice: evidence for a central role in vascular homeostasis. J Thorac Cardiovasc Surg. 2004 Oct; 128(4):595-601. PMID: 15457161.
      View in: PubMed
    52. Murphy GS, Szokol JW, Nitsun M, Alspach DA, Avram MJ, Vender JS, Votapka TV, Rosengart TK. The failure of retrograde autologous priming of the cardiopulmonary bypass circuit to reduce blood use after cardiac surgical procedures. Anesth Analg. 2004 May; 98(5):1201-7, table of contents. PMID: 15105188.
      View in: PubMed
    53. Retuerto MA, Schalch P, Patejunas G, Carbray J, Liu N, Esser K, Crystal RG, Rosengart TK. Angiogenic pretreatment improves the efficacy of cellular cardiomyoplasty performed with fetal cardiomyocyte implantation. J Thorac Cardiovasc Surg. 2004 Apr; 127(4):1041-9; discussion 1049-51. PMID: 15052201.
      View in: PubMed
    54. Schalch P, Rahman GF, Patejunas G, Goldschmidt RA, Carbray J, Retuerto MA, Kim D, Esser K, Crystal RG, Rosengart TK. Adenoviral-mediated transfer of vascular endothelial growth factor 121 cDNA enhances myocardial perfusion and exercise performance in the nonischemic state. J Thorac Cardiovasc Surg. 2004 Feb; 127(2):535-40. PMID: 14762365.
      View in: PubMed
    55. Whitlock PR, Hackett NR, Leopold PL, Rosengart TK, Crystal RG. Adenovirus-mediated transfer of a minigene expressing multiple isoforms of VEGF is more effective at inducing angiogenesis than comparable vectors expressing individual VEGF cDNAs. Mol Ther. 2004 Jan; 9(1):67-75. PMID: 14741779.
      View in: PubMed
    56. Syed IS, Sanborn TA, Rosengart TK. Therapeutic angiogenesis: a biologic bypass. Cardiology. 2004; 101(1-3):131-43. PMID: 14988635.
      View in: PubMed
    57. Rosengart TK. Introduction: the era of cardiac biointerventions. Semin Thorac Cardiovasc Surg. 2003 Jul; 15(3):217-21. PMID: 12973699.
      View in: PubMed
    58. Murphy GS, Szokol JW, Marymont JH, Vender JS, Avram MJ, Rosengart TK, Alwawi EA. Recovery of neuromuscular function after cardiac surgery: pancuronium versus rocuronium. Anesth Analg. 2003 May; 96(5):1301-7, table of contents. PMID: 12707123.
      View in: PubMed
    59. Ben-Gary H, McKinney RL, Rosengart T, Lesser ML, Crystal RG. Systemic interleukin-6 responses following administration of adenovirus gene transfer vectors to humans by different routes. Mol Ther. 2002 Aug; 6(2):287-97. PMID: 12349828.
      View in: PubMed
    60. Leotta E, Patejunas G, Murphy G, Szokol J, McGregor L, Carbray J, Hamawy A, Winchester D, Hackett N, Crystal R, Rosengart T. Gene therapy with adenovirus-mediated myocardial transfer of vascular endothelial growth factor 121 improves cardiac performance in a pacing model of congestive heart failure. J Thorac Cardiovasc Surg. 2002 Jun; 123(6):1101-13. PMID: 12063456.
      View in: PubMed
    61. Murphy GS, Szokol JW, Marymont JH, Avram MJ, Vender JS, Rosengart TK. Impact of shorter-acting neuromuscular blocking agents on fast-track recovery of the cardiac surgical patient. Anesthesiology. 2002 Mar; 96(3):600-6. PMID: 11873034.
      View in: PubMed
    62. Rosengart TK, Finnin EB, Kim DY, Samy SA, Tanhehco Y, Ko W, Lang SJ, Krieger KH, Isom OW. Open heart surgery in the elderly: results from a consecutive series of 100 patients aged 85 years or older. Am J Med. 2002 Feb 1; 112(2):143-7. PMID: 11835954.
      View in: PubMed
    63. Szokol JW, Murphy GS, Stagl RD, Rosengart T. Enlarged abnormal anatomic structure adjacent to the aortic valve. J Cardiothorac Vasc Anesth. 2002 Feb; 16(1):125-6. PMID: 11854892.
      View in: PubMed
    64. Crystal RG, Harvey BG, Wisnivesky JP, O'Donoghue KA, Chu KW, Maroni J, Muscat JC, Pippo AL, Wright CE, Kaner RJ, Leopold PL, Kessler PD, Rasmussen HS, Rosengart TK, Hollmann C. Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions. Hum Gene Ther. 2002 Jan 1; 13(1):65-100. PMID: 11779413.
      View in: PubMed
    65. Rosengart TK. Anticoagulation self-testing after heart valve replacement. J Heart Valve Dis. 2002 Jan; 11 Suppl 1:S61-5. PMID: 11843523.
      View in: PubMed
    66. Harvey BG, Maroni J, O'Donoghue KA, Chu KW, Muscat JC, Pippo AL, Wright CE, Hollmann C, Wisnivesky JP, Kessler PD, Rasmussen HS, Rosengart TK, Crystal RG. Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditions. Hum Gene Ther. 2002 Jan 1; 13(1):15-63. PMID: 11779412.
      View in: PubMed
    67. Landesberg LJ, Ramalingam R, Lee K, Rosengart TK, Crystal RG. Upregulation of transcription factors in lung in the early phase of postpneumonectomy lung growth. Am J Physiol Lung Cell Mol Physiol. 2001 Nov; 281(5):L1138-49. PMID: 11597905.
      View in: PubMed
    68. Hamawy AH, Lee LY, Samy SA, Polce DR, Szulc M, Vazquez M, Rosengart TK. Transmyocardial laser revascularization dose response: enhanced perfusion in a porcine ischemia model as a function of channel density. Ann Thorac Surg. 2001 Sep; 72(3):817-22. PMID: 11565664.
      View in: PubMed
    69. Sanborn TA, Hackett NR, Lee LY, El-Sawy T, Blanco I, Tarazona N, Deutsch E, Crystal R, Rosengart TK. Percutaneous endocardial transfer and expression of genes to the myocardium utilizing fluoroscopic guidance. Catheter Cardiovasc Interv. 2001 Feb; 52(2):260-6. PMID: 11170342.
      View in: PubMed
    70. Rosengart TK, Hillebrand K. Gene therapy for coronary artery disease. Adv Card Surg. 2001; 13:107-20. PMID: 11209652.
      View in: PubMed
    71. Hackett NR, El Sawy T, Lee LY, Silva I, O'Leary J, Rosengart TK, Crystal RG. Use of quantitative TaqMan real-time PCR to track the time-dependent distribution of gene transfer vectors in vivo. Mol Ther. 2000 Dec; 2(6):649-56. PMID: 11124067.
      View in: PubMed
    72. Simons M, Bonow RO, Chronos NA, Cohen DJ, Giordano FJ, Hammond HK, Laham RJ, Li W, Pike M, Sellke FW, Stegmann TJ, Udelson JE, Rosengart TK. Clinical trials in coronary angiogenesis: issues, problems, consensus: An expert panel summary. Circulation. 2000 Sep 12; 102(11):E73-86. PMID: 10982554.
      View in: PubMed
    73. Lee LY, O'Hara MF, Finnin EB, Hachamovitch R, Szulc M, Kligfield PD, Okin PM, Isom OW, Rosengart TK. Transmyocardial laser revascularization with excimer laser: clinical results at 1 year. Ann Thorac Surg. 2000 Aug; 70(2):498-503. PMID: 10969670.
      View in: PubMed
    74. McCaffrey TA, Fu C, Du B, Eksinar S, Kent KC, Bush H, Kreiger K, Rosengart T, Cybulsky MI, Silverman ES, Collins T. High-level expression of Egr-1 and Egr-1-inducible genes in mouse and human atherosclerosis. J Clin Invest. 2000 Mar; 105(5):653-62. PMID: 10712437; PMCID: PMC289183.
    75. Lee LY, Patel SR, Hackett NR, Mack CA, Polce DR, El-Sawy T, Hachamovitch R, Zanzonico P, Sanborn TA, Parikh M, Isom OW, Crystal RG, Rosengart TK. Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothelial growth factor 121. Ann Thorac Surg. 2000 Jan; 69(1):14-23; discussion 23-4. PMID: 10654479.
      View in: PubMed
    76. Hamawy AH, Lee LY, Crystal RG, Rosengart TK. Cardiac angiogenesis and gene therapy: a strategy for myocardial revascularization. Curr Opin Cardiol. 1999 Nov; 14(6):515-22. PMID: 10579070.
      View in: PubMed
    77. Rosengart TK, Lee LY, Patel SR, Kligfield PD, Okin PM, Hackett NR, Isom OW, Crystal RG. Six-month assessment of a phase I trial of angiogenic gene therapy for the treatment of coronary artery disease using direct intramyocardial administration of an adenovirus vector expressing the VEGF121 cDNA. Ann Surg. 1999 Oct; 230(4):466-70; discussion 470-2. PMID: 10522716; PMCID: PMC1420895.
    78. Rosengart TK, Lee LY, Patel SR, Sanborn TA, Parikh M, Bergman GW, Hachamovitch R, Szulc M, Kligfield PD, Okin PM, Hahn RT, Devereux RB, Post MR, Hackett NR, Foster T, Grasso TM, Lesser ML, Isom OW, Crystal RG. Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease. Circulation. 1999 Aug 3; 100(5):468-74. PMID: 10430759.
      View in: PubMed
    79. Harvey BG, Hackett NR, El-Sawy T, Rosengart TK, Hirschowitz EA, Lieberman MD, Lesser ML, Crystal RG. Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs. J Virol. 1999 Aug; 73(8):6729-42. PMID: 10400771; PMCID: PMC112758.
    80. Boyd WC, Rosengart TK, Hartman GS. Isolated left ventricular diverticulum in an adult. J Cardiothorac Vasc Anesth. 1999 Aug; 13(4):468-70. PMID: 10468265.
      View in: PubMed
    81. Lee LY, Zhou X, Polce DR, El-Sawy T, Patel SR, Thakker GD, Narumi K, Crystal RG, Rosengart TK. Exogenous control of cardiac gene therapy: evidence of regulated myocardial transgene expression after adenovirus and adeno-associated virus transfer of expression cassettes containing corticosteroid response element promoters. J Thorac Cardiovasc Surg. 1999 Jul; 118(1):26-4, discussion 34-5. PMID: 10384181.
      View in: PubMed
    82. Patel SR, Lee LY, Mack CA, Polce DR, El-Sawy T, Hackett NR, Ilercil A, Jones EC, Hahn RT, Isom OW, Rosengart TK, Crystal RG. Safety of direct myocardial administration of an adenovirus vector encoding vascular endothelial growth factor 121. Hum Gene Ther. 1999 May 20; 10(8):1331-48. PMID: 10365664.
      View in: PubMed
    83. Thakker GD, Hajjar DP, Muller WA, Rosengart TK. The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling. J Biol Chem. 1999 Apr 9; 274(15):10002-7. PMID: 10187776.
      View in: PubMed
    84. Korst RJ, Rosengart TK. Operative strategies for resection of pulmonary sarcomas extending into the left atrium. Ann Thorac Surg. 1999 Apr; 67(4):1165-7. PMID: 10320276.
      View in: PubMed
    85. Rosengart TK, Patel SR, Crystal RG. Therapeutic angiogenesis: protein and gene therapy delivery strategies. J Cardiovasc Risk. 1999 Feb; 6(1):29-40. PMID: 10197290.
      View in: PubMed
    86. Lee LY, Rosengart TK. Transmyocardial laser revascularization and angiogenesis: the potential for therapeutic benefit. Semin Thorac Cardiovasc Surg. 1999 Jan; 11(1):29-35. PMID: 9930709.
      View in: PubMed
    87. Rosengart TK, O'Hara M, Lang SJ, Ko W, Altorki N, Krieger KH, Isom OW. Outcome analysis of 245 CarboMedics and St. Jude valves implanted at the same institution. Ann Thorac Surg. 1998 Nov; 66(5):1684-91. PMID: 9875772.
      View in: PubMed
    88. DeBois WJ, Rosengart TK. Retrograde autologous priming reduces blood use. Ann Thorac Surg. 1998 Sep; 66(3):987-8. PMID: 9768986.
      View in: PubMed
    89. Mack CA, Magovern CJ, Budenbender KT, Patel SR, Schwarz EA, Zanzonico P, Ferris B, Sanborn T, Isom P, Ferris B, Sanborn T, Isom OW, Crystal RG, Rosengart TK. Salvage angiogenesis induced by adenovirus-mediated gene transfer of vascular endothelial growth factor protects against ischemic vascular occlusion. J Vasc Surg. 1998 Apr; 27(4):699-709. PMID: 9576084.
      View in: PubMed
    90. Rosengart TK, DeBois W, O'Hara M, Helm R, Gomez M, Lang SJ, Altorki N, Ko W, Hartman GS, Isom OW, Krieger KH. Retrograde autologous priming for cardiopulmonary bypass: a safe and effective means of decreasing hemodilution and transfusion requirements. J Thorac Cardiovasc Surg. 1998 Feb; 115(2):426-38; discussion 438-9. PMID: 9475538.
      View in: PubMed
    91. Klemperer JD, Ko W, Krieger KH, Connolly M, Rosengart TK, Altorki NK, Lang S, Isom OW. Cardiac operations in patients with cirrhosis. Ann Thorac Surg. 1998 Jan; 65(1):85-7. PMID: 9456100.
      View in: PubMed
    92. Mack CA, Patel SR, Schwarz EA, Zanzonico P, Hahn RT, Ilercil A, Devereux RB, Goldsmith SJ, Christian TF, Sanborn TA, Kovesdi I, Hackett N, Isom OW, Crystal RG, Rosengart TK. Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart. J Thorac Cardiovasc Surg. 1998 Jan; 115(1):168-76; discussion 176-7. PMID: 9451061.
      View in: PubMed
    93. Helm RE, Rosengart TK, Gomez M, Klemperer JD, DeBois WJ, Velasco F, Gold JP, Altorki NK, Lang S, Thomas S, Isom OW, Krieger KH. Comprehensive multimodality blood conservation: 100 consecutive CABG operations without transfusion. Ann Thorac Surg. 1998 Jan; 65(1):125-36. PMID: 9456106.
      View in: PubMed
    94. Mack CA, Patel SR, Rosengart TK. Myocardial angiogenesis as a possible mechanism for TMLR efficacy. J Clin Laser Med Surg. 1997 Dec; 15(6):275-9. PMID: 9641083.
      View in: PubMed
    95. Rosengart TK. Transmyocardial laser revascularization--a technique in evolution. J Clin Laser Med Surg. 1997 Dec; 15(6):299-300. PMID: 9641087.
      View in: PubMed
    96. Fang WC, Helm RE, Krieger KH, Rosengart TK, DuBois WJ, Sason C, Lesser ML, Isom OW, Gold JP. Impact of minimum hematocrit during cardiopulmonary bypass on mortality in patients undergoing coronary artery surgery. Circulation. 1997 Nov 4; 96(9 Suppl):II-194-9. PMID: 9386097.
      View in: PubMed
    97. Mack CA, Magovern CJ, Hahn RT, Sanborn T, Lanning L, Ko W, Isom OW, Rosengart TK. Channel patency and neovascularization after transmyocardial revascularization using an excimer laser: results and comparisons to nonlased channels. Circulation. 1997 Nov 4; 96(9 Suppl):II-65-9. PMID: 9386077.
      View in: PubMed
    98. Rosengart TK, Budenbender KT, Duenas M, Mack CA, Zhang QX, Isom OW. Therapeutic angiogenesis: a comparative study of the angiogenic potential of acidic fibroblast growth factor and heparin. J Vasc Surg. 1997 Aug; 26(2):302-12. PMID: 9279319.
      View in: PubMed
    99. Rosengart TK, Helm RE, DeBois WJ, Garcia N, Krieger KH, Isom OW. Open heart operations without transfusion using a multimodality blood conservation strategy in 50 Jehovah's Witness patients: implications for a "bloodless" surgical technique. J Am Coll Surg. 1997 Jun; 184(6):618-29. PMID: 9179119.
      View in: PubMed
    100. Rosengart TK, Lang S, Helm R, Friedman D. Open heart surgery in the pediatric Jehovah's Witness population: no longer "Russian roulette". Pediatr Cardiol. 1997 May-Jun; 18(3):245-6. PMID: 9142725.
      View in: PubMed
    101. Mueller RL, Rosengart TK, Isom OW. The history of surgery for ischemic heart disease. Ann Thorac Surg. 1997 Mar; 63(3):869-78. PMID: 9066430.
      View in: PubMed
    102. Zhang QX, Magovern CJ, Mack CA, Budenbender KT, Ko W, Rosengart TK. Vascular endothelial growth factor is the major angiogenic factor in omentum: mechanism of the omentum-mediated angiogenesis. J Surg Res. 1997 Feb 1; 67(2):147-54. PMID: 9073561.
      View in: PubMed
    103. Magovern CJ, Mack CA, Zhang J, Rosengart TK, Isom OW, Crystal RG. Regional angiogenesis induced in nonischemic tissue by an adenoviral vector expressing vascular endothelial growth factor. Hum Gene Ther. 1997 Jan 20; 8(2):215-27. PMID: 9017425.
      View in: PubMed
    104. Mack CA, Song WR, Carpenter H, Wickham TJ, Kovesdi I, Harvey BG, Magovern CJ, Isom OW, Rosengart T, Falck-Pedersen E, Hackett NR, Crystal RG, Mastrangeli A. Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype. Hum Gene Ther. 1997 Jan 1; 8(1):99-109. PMID: 8989999.
      View in: PubMed
    105. Rosengart TK, Krieger KH. Predicting transfusion. Ann Thorac Surg. 1996 Dec; 62(6):1885-6. PMID: 8957423.
      View in: PubMed
    106. Helm RE, Klemperer JD, Rosengart TK, Gold JP, Peterson P, DeBois W, Altorki NK, Lang S, Thomas S, Isom OW, Krieger KH. Intraoperative autologous blood donation preserves red cell mass but does not decrease postoperative bleeding. Ann Thorac Surg. 1996 Nov; 62(5):1431-41. PMID: 8893580.
      View in: PubMed
    107. Magovern CJ, Mack CA, Zhang J, Hahn RT, Ko W, Isom OW, Crystal RG, Rosengart TK. Direct in vivo gene transfer to canine myocardium using a replication-deficient adenovirus vector. Ann Thorac Surg. 1996 Aug; 62(2):425-33; discussion 433-4. PMID: 8694601.
      View in: PubMed
    108. Upadhyay A, Maurer J, Turner J, Tiszenkel H, Rosengart T. Elective bedside tracheostomy in the intensive care unit. J Am Coll Surg. 1996 Jul; 183(1):51-5. PMID: 8673307.
      View in: PubMed
    109. Velasco FT, Ko W, Rosengart T, Altorki N, Lang S, Gold JP, Krieger KH, Isom OW. Cost containment in cardiac surgery: results with a critical pathway for coronary bypass surgery at the New York hospital-Cornell Medical Center. Best Pract Benchmarking Healthc. 1996 Jan-Feb; 1(1):21-8. PMID: 9192587.
      View in: PubMed
    110. Levy JH, Pifarre R, Schaff HV, Horrow JC, Albus R, Spiess B, Rosengart TK, Murray J, Clark RE, Smith P. A multicenter, double-blind, placebo-controlled trial of aprotinin for reducing blood loss and the requirement for donor-blood transfusion in patients undergoing repeat coronary artery bypass grafting. Circulation. 1995 Oct 15; 92(8):2236-44. PMID: 7554207.
      View in: PubMed
    111. Zhang QX, Duenas M, Rosengart T. Effect of tumor necrosis factor-alpha on a cell line transformed by a secreted form of human fibroblast growth factor-1 gene and on its parental cell line. Cancer Lett. 1995 Feb 10; 89(1):49-54. PMID: 7533657.
      View in: PubMed
    112. Munver R, Schulman IC, Wolf DJ, Rosengart TK. Heparin-induced thrombocytopenia and thrombosis: presentation after cardiopulmonary bypass. Ann Thorac Surg. 1994 Dec; 58(6):1764-6. PMID: 7979757.
      View in: PubMed
    113. Rosengart TK, Helm RE, Klemperer J, Krieger KH, Isom OW. Combined aprotinin and erythropoietin use for blood conservation: results with Jehovah's Witnesses. Ann Thorac Surg. 1994 Nov; 58(5):1397-403. PMID: 7526810.
      View in: PubMed
    114. Aldrich HR, Girardi L, Bush HL, Devereux RB, Rosengart TK. Recurrent systemic embolization caused by aortic thrombi. Ann Thorac Surg. 1994 Feb; 57(2):466-8. PMID: 8311614.
      View in: PubMed
    115. Rosengart TK, Krieger K, Lang SJ, Gold JP, Altorki N, Roussel M, Debois WJ, Isom OW. Reoperative coronary artery bypass surgery. Improved preservation of myocardial function with retrograde cardioplegia. Circulation. 1993 Nov; 88(5 Pt 2):II330-5. PMID: 8222174.
      View in: PubMed
    116. Rosengart TK. Risk analysis of primary versus reoperative coronary artery bypass grafting. Ann Thorac Surg. 1993 Nov; 56(5 Suppl):S74-7. PMID: 8239842.
      View in: PubMed
    117. Helm RE, Gold JP, Rosengart TK, Zelano JA, Isom OW, Krieger KH. Erythropoietin in cardiac surgery. J Card Surg. 1993 Sep; 8(5):579-606. PMID: 8219540.
      View in: PubMed
    118. Rosengart TK, Stark JF. Repair of atrial septal defect through a right thoracotomy. Ann Thorac Surg. 1993 May; 55(5):1138-40. PMID: 8494422.
      View in: PubMed
    119. Rosengart TK, Redel DA, Stark JF. Surgical repair of aorto-right ventricular tunnel in an infant. Ann Thorac Surg. 1993 Feb; 55(2):520-2. PMID: 8431072.
      View in: PubMed
    120. Isom OW, Rosengart TK. Percutaneous aortic valvuloplasty: off the bandwagon, again. J Am Coll Cardiol. 1992 Oct; 20(4):804-5. PMID: 1527291.
      View in: PubMed
    121. Rosengart TK, Martini N, Ghosn P, Burt M. Multiple primary lung carcinomas: prognosis and treatment. Ann Thorac Surg. 1991 Oct; 52(4):773-8; discussion 778-9. PMID: 1929628.
      View in: PubMed
    122. Rosengart TK, Rotterdam H, Ranson JH. Eosinophilic cholangitis: a self-limited cause of extrahepatic biliary obstruction. Am J Gastroenterol. 1990 May; 85(5):582-5. PMID: 2337061.
      View in: PubMed
    123. Rosengart TK, Coppa GF. Abdominal mycobacterial infections in immunocompromised patients. Am J Surg. 1990 Jan; 159(1):125-31. PMID: 2294789.
      View in: PubMed
    124. Kupferschmid JP, Rosengart TK, McIntosh CL, Leon MB, Clark RE. Amiodarone-induced complications after cardiac operation for obstructive hypertrophic cardiomyopathy. Ann Thorac Surg. 1989 Sep; 48(3):359-64. PMID: 2774719.
      View in: PubMed
    125. Rosengart TK, Pass H, Cannon R, Miller DL, Solomon D, Clark RE. Ruptured gastroepiploic artery aneurysm and vascular collapse in a patient with thoracic aneurysm. J Cardiovasc Surg (Torino). 1989 May-Jun; 30(3):514-6. PMID: 2745544.
      View in: PubMed
    126. Rosengart TK, Kuperschmid JP, Maciag T, Clark RE. Pharmacokinetics and distribution of heparin-binding growth factor I (endothelial cell growth factor) in the rat. Circ Res. 1989 Feb; 64(2):227-34. PMID: 2463884.
      View in: PubMed
    127. Rosengart TK, Johnson WV, Friesel R, Clark R, Maciag T. Heparin protects heparin-binding growth factor-I from proteolytic inactivation in vitro. Biochem Biophys Res Commun. 1988 Apr 15; 152(1):432-40. PMID: 2451918.
      View in: PubMed
    128. Rosengart TK, Kupferschmid JP, Ferrans VJ, Casscells W, Maciag T, Clark RE. Heparin-binding growth factor-I (endothelial cell growth factor) binds to endothelium in vivo. J Vasc Surg. 1988 Feb; 7(2):311-7. PMID: 2448501.
      View in: PubMed
    ROSENGART's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _