Keywords
Last Name
Institution

TODD ROSENGART

TitleChair
InstitutionBaylor College of Medicine
DepartmentDepartment of Surgery
Address6501 Fannin, Suite NC114
Houston TX 77030
Other Positions
TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Surgery
DivisionSurgery


 Overview 
 overview
Dr. Todd K. Rosengart is a National Institutes of Health (NIH)-supported scientist with uninterrupted extramural funding since 1998. An extensively published investigator, he is also editor of Seminars in Thoracic and Cardiovascular Surgery and was recently appointed member of the NIH Bioengineering, Technology, and Surgical Sciences (BTSS) study section.

Dr. Rosengart was one of the pioneers in the field of gene therapy, with work beginning in the early 1990s. He now leads a team of scientists engaged in the study of cardiac cellular reprogramming.

As a physician-entrepreneur, he is co-founder of Vitals.com, a leading health provider search and physician/patient interface website with over 13 million monthly visits. He holds twelve patents, including those for a method of inducing angiogenesis.

 keywords
Gene therapy
Cellular reprogramming
Angiogenesis


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Rosengart TK. Total arterial revascularization: When will its time come? J Thorac Cardiovasc Surg. 2014 Oct; 148(4):1244-5.
    View in: PubMed
  2. Preventza O, Garcia A, Cooley DA, Tuluca A, Simpson KH, Bakaeen FG, Omer S, Cornwell L, Rosengart TK, Coselli JS. Reoperations on the total aortic arch in 119 patients: Short- and mid-term outcomes, focusing on composite adverse outcomes and survival analysis. J Thorac Cardiovasc Surg. 2014 Jul 30.
    View in: PubMed
  3. Rosengart TK. The 1000th VAD, the Great Rivalry, and the Grand Experiment of the Texas Medical Center. Semin Thorac Cardiovasc Surg. 2014; 26(1):1-3.
    View in: PubMed
  4. Rosengart TK. The 1,000th VAD, the Great Rivalry, and the Grand Experiment of the Texas Medical Center. Tex Heart Inst J. 2014 Apr; 41(2):112-4.
    View in: PubMed
  5. Mathison M, Singh VP, Gersch RP, Ramirez MO, Cooney A, Kaminsky SM, Chiuchiolo MJ, Nasser A, Yang J, Crystal RG, Rosengart TK. "Triplet" polycistronic vectors encoding Gata4, Mef2c, and Tbx5 enhances postinfarct ventricular functional improvement compared with singlet vectors. J Thorac Cardiovasc Surg. 2014 Mar 27.
    View in: PubMed
  6. Dathatri S, Gruberg L, Anand J, Romeiser J, Sharma S, Finnin E, Shroyer AL, Rosengart TK. Informed consent for cardiac procedures: deficiencies in patient comprehension with current methods. Ann Thorac Surg. 2014 May; 97(5):1505-12.
    View in: PubMed
  7. Rosengart TK. The 1,000th VAD, the great rivalry, and the grand experiment of the Texas Medical Center. J Thorac Cardiovasc Surg. 2014 Jun; 147(6):1745-7.
    View in: PubMed
  8. Bakaeen FG, Shroyer AL, Gammie JS, Sabik JF, Cornwell LD, Coselli JS, Rosengart TK, O'Brien SM, Wallace A, Shahian DM, Grover FL, Puskas JD. Trends in use of off-pump coronary artery bypass grafting: Results from the Society of Thoracic Surgeons Adult Cardiac Surgery Database. J Thorac Cardiovasc Surg. 2014 Sep; 148(3):856-864.e1.
    View in: PubMed
  9. Omer S, Cornwell LD, Rosengart TK, Kelly RF, Ward HB, Holman WL, Bakaeen FG. Completeness of coronary revascularization and survival: Impact of age and off-pump surgery. J Thorac Cardiovasc Surg. 2014 Jan 15.
    View in: PubMed
  10. Fourman MS, Gersch RP, Phillips BT, Nasser A, Rivara A, Verma R, Dagum AB, Rosengart TK, Bui DT. Comparison of Laser Doppler and Laser-Assisted Indocyanine Green Angiography Prediction of Flap Survival in a Novel Modification of the McFarlane Flap. Ann Plast Surg. 2014 Jan 7.
    View in: PubMed
  11. Kaminsky SM, Rosengart TK, Rosenberg J, Chiuchiolo MJ, Van de Graaf B, Sondhi D, Crystal RG. Gene therapy to stimulate angiogenesis to treat diffuse coronary artery disease. Hum Gene Ther. 2013 Nov; 24(11):948-63.
    View in: PubMed
  12. Liu L, Souto J, Liao W, Jiang Y, Li Y, Nishinakamura R, Huang S, Rosengart T, Yang VW, Schuster M, Ma Y, Yang J. Histone Lysine-specific Demethylase 1 (LSD1) Protein Is Involved in Sal-like Protein 4 (SALL4)-mediated Transcriptional Repression in Hematopoietic Stem Cells. J Biol Chem. 2013 Nov 29; 288(48):34719-28.
    View in: PubMed
  13. Rosengart TK, Romeiser JL, White LJ, Fratello A, Fallon E, Senzel L, Shroyer AL. Platelet activity measured by a rapid turnaround assay identifies coronary artery bypass grafting patients at increased risk for bleeding and transfusion complications after clopidogrel administration. J Thorac Cardiovasc Surg. 2013 Nov; 146(5):1259-1266, 1266.e1; discussion 1266.
    View in: PubMed
  14. Kaminsky SM, Quach L, Chen S, Pierre-Destine L, Van de Graaf B, Monette S, Rosenberg JB, De BP, Sondhi D, Hackett NR, Mezey JG, Rosengart TK, Crystal RG. Safety of direct cardiac administration of AdVEGF-All6A+, a replication-deficient adenovirus vector cDNA/genomic hybrid expressing all three major isoforms of human vascular endothelial growth factor, to the ischemic myocardium of rats. Hum Gene Ther Clin Dev. 2013 Mar; 24(1):38-46.
    View in: PubMed
  15. Price JD, Romeiser JL, Gnerre JM, Shroyer AL, Rosengart TK. Risk analysis for readmission after coronary artery bypass surgery: developing a strategy to reduce readmissions. J Am Coll Surg. 2013 Mar; 216(3):412-9.
    View in: PubMed
  16. Pass H, Rosengart T. Welcome to the new seminars. Semin Thorac Cardiovasc Surg. 2013; 25(1):1.
    View in: PubMed
  17. Rosengart TK. Cardiac cellular reprogramming. Tex Heart Inst J. 2013; 40(5):581-2.
    View in: PubMed
  18. Rosengart TK, Bishawi MM, Halbreiner MS, Fakhoury M, Finnin E, Hollmann C, Shroyer AL, Crystal RG. Long-term follow-up assessment of a phase 1 trial of angiogenic gene therapy using direct intramyocardial administration of an adenoviral vector expressing the VEGF121 cDNA for the treatment of diffuse coronary artery disease. Hum Gene Ther. 2013 Feb; 24(2):203-8.
    View in: PubMed
  19. Mathison M, Gersch RP, Nasser A, Lilo S, Korman M, Fourman M, Hackett N, Shroyer K, Yang J, Ma Y, Crystal RG, Rosengart TK. In vivo cardiac cellular reprogramming efficacy is enhanced by angiogenic preconditioning of the infarcted myocardium with vascular endothelial growth factor. J Am Heart Assoc. 2012 Dec; 1(6):e005652.
    View in: PubMed
  20. Ferraris VA, Saha SP, Oestreich JH, Song HK, Rosengart T, Reece TB, Mazer CD, Bridges CR, Despotis GJ, Jointer K, Clough ER. 2012 update to the Society of Thoracic Surgeons guideline on use of antiplatelet drugs in patients having cardiac and noncardiac operations. Ann Thorac Surg. 2012 Nov; 94(5):1761-81.
    View in: PubMed
  21. Rosengart TK, Fallon E, Crystal RG. Cardiac biointerventions: whatever happened to stem cell and gene therapy? Innovations (Phila). 2012 May-Jun; 7(3):173-9.
    View in: PubMed
  22. Crystal RG, Kaminsky SM, Hackett NR, Rosengart TK. Double-blinded, placebo-controlled, randomized gene therapy using surgery for vector delivery. Hum Gene Ther. 2012 May; 23(5):438-41.
    View in: PubMed
  23. Rosengart TK. Cognitive decline and ischemic microlesions after coronary catheterization: a comparison to coronary artery bypass. Am Heart J. 2012 Apr; 163(4):e13.
    View in: PubMed
  24. Jeremias A, Kaul S, Rosengart TK, Gruberg L, Brown DL. The impact of revascularization on mortality in patients with nonacute coronary artery disease. Am J Med. 2009 Feb; 122(2):152-61.
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  25. Sweet JJ, Finnin E, Wolfe PL, Beaumont JL, Hahn E, Marymont J, Sanborn T, Rosengart TK. Absence of cognitive decline one year after coronary bypass surgery: comparison to nonsurgical and healthy controls. Ann Thorac Surg. 2008 May; 85(5):1571-8.
    View in: PubMed
  26. Rosengart TK, Feldman T, Borger MA, Vassiliades TA, Gillinov AM, Hoercher KJ, Vahanian A, Bonow RO, O'Neill W. Percutaneous and minimally invasive valve procedures: a scientific statement from the American Heart Association Council on Cardiovascular Surgery and Anesthesia, Council on Clinical Cardiology, Functional Genomics and Translational Biology Interdisciplinary Working Group, and Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2008 Apr 1; 117(13):1750-67.
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  27. Rosengart TK. Invited commentary. Ann Thorac Surg. 2008 Jan; 85(1):64.
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  28. Retuerto MA, Beckmann JT, Carbray J, Patejunas G, Sarateanu S, Kane BJ, Smulevitz B, McPherson DD, Rosengart TK. Angiogenic pretreatment to enhance myocardial function after cellular cardiomyoplasty with skeletal myoblasts. J Thorac Cardiovasc Surg. 2007 Feb; 133(2):478-484.e2.
    View in: PubMed
  29. Rosengart TK, Sweet JJ, Finnin E, Wolfe P, Cashy J, Hahn E, Marymont J, Sanborn T. Stable cognition after coronary artery bypass grafting: comparisons with percutaneous intervention and normal controls. Ann Thorac Surg. 2006 Aug; 82(2):597-607.
    View in: PubMed
  30. Sarateanu CS, Retuerto MA, Beckmann JT, McGregor L, Carbray J, Patejunas G, Nayak L, Milbrandt J, Rosengart TK. An Egr-1 master switch for arteriogenesis: studies in Egr-1 homozygous negative and wild-type animals. J Thorac Cardiovasc Surg. 2006 Jan; 131(1):138-45.
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  31. Dang NC, Aboodi MS, Sakaguchi T, Wasserman HS, Argenziano M, Cosgrove DM, Rosengart TK, Feldman T, Block PC, Oz MC. Surgical revision after percutaneous mitral valve repair with a clip: initial multicenter experience. Ann Thorac Surg. 2005 Dec; 80(6):2338-42.
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  32. Amano H, Hackett NR, Kaner RJ, Whitlock P, Rosengart TK, Crystal RG. Alteration of splicing signals in a genomic/cDNA hybrid VEGF gene to modify the ratio of expressed VEGF isoforms enhances safety of angiogenic gene therapy. Mol Ther. 2005 Oct; 12(4):716-24.
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  33. Rosengart TK, Sweet J, Finnin EB, Wolfe P, Cashy J, Hahn E, Marymont J, Sanborn T. Neurocognitive functioning in patients undergoing coronary artery bypass graft surgery or percutaneous coronary intervention: evidence of impairment before intervention compared with normal controls. Ann Thorac Surg. 2005 Oct; 80(4):1327-34; discussion 1334-5.
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  34. Rajamannan NM, Nealis TB, Subramaniam M, Pandya S, Stock SR, Ignatiev CI, Sebo TJ, Rosengart TK, Edwards WD, McCarthy PM, Bonow RO, Spelsberg TC. Calcified rheumatic valve neoangiogenesis is associated with vascular endothelial growth factor expression and osteoblast-like bone formation. Circulation. 2005 Jun 21; 111(24):3296-301.
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  35. Baumgartner WA, Burrows S, del Nido PJ, Gardner TJ, Goldberg S, Gorman RC, Letsou GV, Mascette A, Michler RE, Puskas JD, Rose EA, Rosengart TK, Sellke FW, Shumway SJ, Wilke N. Recommendations of the National Heart, Lung, and Blood Institute Working Group on Future Direction in Cardiac Surgery. Circulation. 2005 Jun 7; 111(22):3007-13.
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  36. Rosengart TK, Chedrawy EG, Patejunas G, Retuarto M. Vascular endothelial growth factor before cells. J Thorac Cardiovasc Surg. 2005 Mar; 129(3):696.
    View in: PubMed
  37. Nayak L, Rosengart TK. Gene therapy for heart failure. Semin Thorac Cardiovasc Surg. 2005; 17(4):343-7.
    View in: PubMed
  38. Schalch P, Patejunas G, Retuerto M, Sarateanu S, Milbrandt J, Thakker G, Kim D, Carbray J, Crystal RG, Rosengart TK. Homozygous deletion of early growth response 1 gene and critical limb ischemia after vascular ligation in mice: evidence for a central role in vascular homeostasis. J Thorac Cardiovasc Surg. 2004 Oct; 128(4):595-601.
    View in: PubMed
  39. Murphy GS, Szokol JW, Nitsun M, Alspach DA, Avram MJ, Vender JS, Votapka TV, Rosengart TK. The failure of retrograde autologous priming of the cardiopulmonary bypass circuit to reduce blood use after cardiac surgical procedures. Anesth Analg. 2004 May; 98(5):1201-7, table of contents.
    View in: PubMed
  40. Retuerto MA, Schalch P, Patejunas G, Carbray J, Liu N, Esser K, Crystal RG, Rosengart TK. Angiogenic pretreatment improves the efficacy of cellular cardiomyoplasty performed with fetal cardiomyocyte implantation. J Thorac Cardiovasc Surg. 2004 Apr; 127(4):1041-9; discussion 1049-51.
    View in: PubMed
  41. Schalch P, Rahman GF, Patejunas G, Goldschmidt RA, Carbray J, Retuerto MA, Kim D, Esser K, Crystal RG, Rosengart TK. Adenoviral-mediated transfer of vascular endothelial growth factor 121 cDNA enhances myocardial perfusion and exercise performance in the nonischemic state. J Thorac Cardiovasc Surg. 2004 Feb; 127(2):535-40.
    View in: PubMed
  42. Whitlock PR, Hackett NR, Leopold PL, Rosengart TK, Crystal RG. Adenovirus-mediated transfer of a minigene expressing multiple isoforms of VEGF is more effective at inducing angiogenesis than comparable vectors expressing individual VEGF cDNAs. Mol Ther. 2004 Jan; 9(1):67-75.
    View in: PubMed
  43. Syed IS, Sanborn TA, Rosengart TK. Therapeutic angiogenesis: a biologic bypass. Cardiology. 2004; 101(1-3):131-43.
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  44. Rosengart TK. Introduction: the era of cardiac biointerventions. Semin Thorac Cardiovasc Surg. 2003 Jul; 15(3):217-21.
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  45. Murphy GS, Szokol JW, Marymont JH, Vender JS, Avram MJ, Rosengart TK, Alwawi EA. Recovery of neuromuscular function after cardiac surgery: pancuronium versus rocuronium. Anesth Analg. 2003 May; 96(5):1301-7, table of contents.
    View in: PubMed
  46. Ben-Gary H, McKinney RL, Rosengart T, Lesser ML, Crystal RG. Systemic interleukin-6 responses following administration of adenovirus gene transfer vectors to humans by different routes. Mol Ther. 2002 Aug; 6(2):287-97.
    View in: PubMed
  47. Leotta E, Patejunas G, Murphy G, Szokol J, McGregor L, Carbray J, Hamawy A, Winchester D, Hackett N, Crystal R, Rosengart T. Gene therapy with adenovirus-mediated myocardial transfer of vascular endothelial growth factor 121 improves cardiac performance in a pacing model of congestive heart failure. J Thorac Cardiovasc Surg. 2002 Jun; 123(6):1101-13.
    View in: PubMed
  48. Murphy GS, Szokol JW, Marymont JH, Avram MJ, Vender JS, Rosengart TK. Impact of shorter-acting neuromuscular blocking agents on fast-track recovery of the cardiac surgical patient. Anesthesiology. 2002 Mar; 96(3):600-6.
    View in: PubMed
  49. Rosengart TK, Finnin EB, Kim DY, Samy SA, Tanhehco Y, Ko W, Lang SJ, Krieger KH, Isom OW. Open heart surgery in the elderly: results from a consecutive series of 100 patients aged 85 years or older. Am J Med. 2002 Feb 1; 112(2):143-7.
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  50. Szokol JW, Murphy GS, Stagl RD, Rosengart T. Enlarged abnormal anatomic structure adjacent to the aortic valve. J Cardiothorac Vasc Anesth. 2002 Feb; 16(1):125-6.
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  51. Crystal RG, Harvey BG, Wisnivesky JP, O'Donoghue KA, Chu KW, Maroni J, Muscat JC, Pippo AL, Wright CE, Kaner RJ, Leopold PL, Kessler PD, Rasmussen HS, Rosengart TK, Hollmann C. Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions. Hum Gene Ther. 2002 Jan 1; 13(1):65-100.
    View in: PubMed
  52. Rosengart TK. Anticoagulation self-testing after heart valve replacement. J Heart Valve Dis. 2002 Jan; 11 Suppl 1:S61-5.
    View in: PubMed
  53. Harvey BG, Maroni J, O'Donoghue KA, Chu KW, Muscat JC, Pippo AL, Wright CE, Hollmann C, Wisnivesky JP, Kessler PD, Rasmussen HS, Rosengart TK, Crystal RG. Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditions. Hum Gene Ther. 2002 Jan 1; 13(1):15-63.
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  54. Landesberg LJ, Ramalingam R, Lee K, Rosengart TK, Crystal RG. Upregulation of transcription factors in lung in the early phase of postpneumonectomy lung growth. Am J Physiol Lung Cell Mol Physiol. 2001 Nov; 281(5):L1138-49.
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  55. Hamawy AH, Lee LY, Samy SA, Polce DR, Szulc M, Vazquez M, Rosengart TK. Transmyocardial laser revascularization dose response: enhanced perfusion in a porcine ischemia model as a function of channel density. Ann Thorac Surg. 2001 Sep; 72(3):817-22.
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  56. Sanborn TA, Hackett NR, Lee LY, El-Sawy T, Blanco I, Tarazona N, Deutsch E, Crystal R, Rosengart TK. Percutaneous endocardial transfer and expression of genes to the myocardium utilizing fluoroscopic guidance. Catheter Cardiovasc Interv. 2001 Feb; 52(2):260-6.
    View in: PubMed
  57. Rosengart TK, Hillebrand K. Gene therapy for coronary artery disease. Adv Card Surg. 2001; 13:107-20.
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  58. Hackett NR, El Sawy T, Lee LY, Silva I, O'Leary J, Rosengart TK, Crystal RG. Use of quantitative TaqMan real-time PCR to track the time-dependent distribution of gene transfer vectors in vivo. Mol Ther. 2000 Dec; 2(6):649-56.
    View in: PubMed
  59. Simons M, Bonow RO, Chronos NA, Cohen DJ, Giordano FJ, Hammond HK, Laham RJ, Li W, Pike M, Sellke FW, Stegmann TJ, Udelson JE, Rosengart TK. Clinical trials in coronary angiogenesis: issues, problems, consensus: An expert panel summary. Circulation. 2000 Sep 12; 102(11):E73-86.
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  60. Lee LY, O'Hara MF, Finnin EB, Hachamovitch R, Szulc M, Kligfield PD, Okin PM, Isom OW, Rosengart TK. Transmyocardial laser revascularization with excimer laser: clinical results at 1 year. Ann Thorac Surg. 2000 Aug; 70(2):498-503.
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  61. McCaffrey TA, Fu C, Du B, Eksinar S, Kent KC, Bush H, Kreiger K, Rosengart T, Cybulsky MI, Silverman ES, Collins T. High-level expression of Egr-1 and Egr-1-inducible genes in mouse and human atherosclerosis. J Clin Invest. 2000 Mar; 105(5):653-62.
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  62. Lee LY, Patel SR, Hackett NR, Mack CA, Polce DR, El-Sawy T, Hachamovitch R, Zanzonico P, Sanborn TA, Parikh M, Isom OW, Crystal RG, Rosengart TK. Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothelial growth factor 121. Ann Thorac Surg. 2000 Jan; 69(1):14-23; discussion 23-4.
    View in: PubMed
  63. Hamawy AH, Lee LY, Crystal RG, Rosengart TK. Cardiac angiogenesis and gene therapy: a strategy for myocardial revascularization. Curr Opin Cardiol. 1999 Nov; 14(6):515-22.
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  64. Rosengart TK, Lee LY, Patel SR, Kligfield PD, Okin PM, Hackett NR, Isom OW, Crystal RG. Six-month assessment of a phase I trial of angiogenic gene therapy for the treatment of coronary artery disease using direct intramyocardial administration of an adenovirus vector expressing the VEGF121 cDNA. Ann Surg. 1999 Oct; 230(4):466-70; discussion 470-2.
    View in: PubMed
  65. Rosengart TK, Lee LY, Patel SR, Sanborn TA, Parikh M, Bergman GW, Hachamovitch R, Szulc M, Kligfield PD, Okin PM, Hahn RT, Devereux RB, Post MR, Hackett NR, Foster T, Grasso TM, Lesser ML, Isom OW, Crystal RG. Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease. Circulation. 1999 Aug 3; 100(5):468-74.
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  66. Harvey BG, Hackett NR, El-Sawy T, Rosengart TK, Hirschowitz EA, Lieberman MD, Lesser ML, Crystal RG. Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs. J Virol. 1999 Aug; 73(8):6729-42.
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  67. Boyd WC, Rosengart TK, Hartman GS. Isolated left ventricular diverticulum in an adult. J Cardiothorac Vasc Anesth. 1999 Aug; 13(4):468-70.
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  68. Lee LY, Zhou X, Polce DR, El-Sawy T, Patel SR, Thakker GD, Narumi K, Crystal RG, Rosengart TK. Exogenous control of cardiac gene therapy: evidence of regulated myocardial transgene expression after adenovirus and adeno-associated virus transfer of expression cassettes containing corticosteroid response element promoters. J Thorac Cardiovasc Surg. 1999 Jul; 118(1):26-4, discussion 34-5.
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  69. Patel SR, Lee LY, Mack CA, Polce DR, El-Sawy T, Hackett NR, Ilercil A, Jones EC, Hahn RT, Isom OW, Rosengart TK, Crystal RG. Safety of direct myocardial administration of an adenovirus vector encoding vascular endothelial growth factor 121. Hum Gene Ther. 1999 May 20; 10(8):1331-48.
    View in: PubMed
  70. Thakker GD, Hajjar DP, Muller WA, Rosengart TK. The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling. J Biol Chem. 1999 Apr 9; 274(15):10002-7.
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  71. Korst RJ, Rosengart TK. Operative strategies for resection of pulmonary sarcomas extending into the left atrium. Ann Thorac Surg. 1999 Apr; 67(4):1165-7.
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  72. Rosengart TK, Patel SR, Crystal RG. Therapeutic angiogenesis: protein and gene therapy delivery strategies. J Cardiovasc Risk. 1999 Feb; 6(1):29-40.
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  73. Lee LY, Rosengart TK. Transmyocardial laser revascularization and angiogenesis: the potential for therapeutic benefit. Semin Thorac Cardiovasc Surg. 1999 Jan; 11(1):29-35.
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  74. Rosengart TK, O'Hara M, Lang SJ, Ko W, Altorki N, Krieger KH, Isom OW. Outcome analysis of 245 CarboMedics and St. Jude valves implanted at the same institution. Ann Thorac Surg. 1998 Nov; 66(5):1684-91.
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  75. DeBois WJ, Rosengart TK. Retrograde autologous priming reduces blood use. Ann Thorac Surg. 1998 Sep; 66(3):987-8.
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  76. Mack CA, Magovern CJ, Budenbender KT, Patel SR, Schwarz EA, Zanzonico P, Ferris B, Sanborn T, Isom P, Ferris B, Sanborn T, Isom OW, Crystal RG, Rosengart TK. Salvage angiogenesis induced by adenovirus-mediated gene transfer of vascular endothelial growth factor protects against ischemic vascular occlusion. J Vasc Surg. 1998 Apr; 27(4):699-709.
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  77. Rosengart TK, DeBois W, O'Hara M, Helm R, Gomez M, Lang SJ, Altorki N, Ko W, Hartman GS, Isom OW, Krieger KH. Retrograde autologous priming for cardiopulmonary bypass: a safe and effective means of decreasing hemodilution and transfusion requirements. J Thorac Cardiovasc Surg. 1998 Feb; 115(2):426-38; discussion 438-9.
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  78. Klemperer JD, Ko W, Krieger KH, Connolly M, Rosengart TK, Altorki NK, Lang S, Isom OW. Cardiac operations in patients with cirrhosis. Ann Thorac Surg. 1998 Jan; 65(1):85-7.
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  79. Helm RE, Rosengart TK, Gomez M, Klemperer JD, DeBois WJ, Velasco F, Gold JP, Altorki NK, Lang S, Thomas S, Isom OW, Krieger KH. Comprehensive multimodality blood conservation: 100 consecutive CABG operations without transfusion. Ann Thorac Surg. 1998 Jan; 65(1):125-36.
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  80. Mack CA, Patel SR, Schwarz EA, Zanzonico P, Hahn RT, Ilercil A, Devereux RB, Goldsmith SJ, Christian TF, Sanborn TA, Kovesdi I, Hackett N, Isom OW, Crystal RG, Rosengart TK. Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart. J Thorac Cardiovasc Surg. 1998 Jan; 115(1):168-76; discussion 176-7.
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  81. Mack CA, Patel SR, Rosengart TK. Myocardial angiogenesis as a possible mechanism for TMLR efficacy. J Clin Laser Med Surg. 1997 Dec; 15(6):275-9.
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  82. Rosengart TK. Transmyocardial laser revascularization--a technique in evolution. J Clin Laser Med Surg. 1997 Dec; 15(6):299-300.
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  83. Fang WC, Helm RE, Krieger KH, Rosengart TK, DuBois WJ, Sason C, Lesser ML, Isom OW, Gold JP. Impact of minimum hematocrit during cardiopulmonary bypass on mortality in patients undergoing coronary artery surgery. Circulation. 1997 Nov 4; 96(9 Suppl):II-194-9.
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  84. Mack CA, Magovern CJ, Hahn RT, Sanborn T, Lanning L, Ko W, Isom OW, Rosengart TK. Channel patency and neovascularization after transmyocardial revascularization using an excimer laser: results and comparisons to nonlased channels. Circulation. 1997 Nov 4; 96(9 Suppl):II-65-9.
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  85. Rosengart TK, Budenbender KT, Duenas M, Mack CA, Zhang QX, Isom OW. Therapeutic angiogenesis: a comparative study of the angiogenic potential of acidic fibroblast growth factor and heparin. J Vasc Surg. 1997 Aug; 26(2):302-12.
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  86. Rosengart TK, Helm RE, DeBois WJ, Garcia N, Krieger KH, Isom OW. Open heart operations without transfusion using a multimodality blood conservation strategy in 50 Jehovah's Witness patients: implications for a "bloodless" surgical technique. J Am Coll Surg. 1997 Jun; 184(6):618-29.
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  87. Rosengart TK, Lang S, Helm R, Friedman D. Open heart surgery in the pediatric Jehovah's Witness population: no longer "Russian roulette". Pediatr Cardiol. 1997 May-Jun; 18(3):245-6.
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  88. Mueller RL, Rosengart TK, Isom OW. The history of surgery for ischemic heart disease. Ann Thorac Surg. 1997 Mar; 63(3):869-78.
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  89. Zhang QX, Magovern CJ, Mack CA, Budenbender KT, Ko W, Rosengart TK. Vascular endothelial growth factor is the major angiogenic factor in omentum: mechanism of the omentum-mediated angiogenesis. J Surg Res. 1997 Feb 1; 67(2):147-54.
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  90. Magovern CJ, Mack CA, Zhang J, Rosengart TK, Isom OW, Crystal RG. Regional angiogenesis induced in nonischemic tissue by an adenoviral vector expressing vascular endothelial growth factor. Hum Gene Ther. 1997 Jan 20; 8(2):215-27.
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  91. Mack CA, Song WR, Carpenter H, Wickham TJ, Kovesdi I, Harvey BG, Magovern CJ, Isom OW, Rosengart T, Falck-Pedersen E, Hackett NR, Crystal RG, Mastrangeli A. Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype. Hum Gene Ther. 1997 Jan 1; 8(1):99-109.
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  92. Rosengart TK, Krieger KH. Predicting transfusion. Ann Thorac Surg. 1996 Dec; 62(6):1885-6.
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  93. Helm RE, Klemperer JD, Rosengart TK, Gold JP, Peterson P, DeBois W, Altorki NK, Lang S, Thomas S, Isom OW, Krieger KH. Intraoperative autologous blood donation preserves red cell mass but does not decrease postoperative bleeding. Ann Thorac Surg. 1996 Nov; 62(5):1431-41.
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  94. Magovern CJ, Mack CA, Zhang J, Hahn RT, Ko W, Isom OW, Crystal RG, Rosengart TK. Direct in vivo gene transfer to canine myocardium using a replication-deficient adenovirus vector. Ann Thorac Surg. 1996 Aug; 62(2):425-33; discussion 433-4.
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  95. Upadhyay A, Maurer J, Turner J, Tiszenkel H, Rosengart T. Elective bedside tracheostomy in the intensive care unit. J Am Coll Surg. 1996 Jul; 183(1):51-5.
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  96. Velasco FT, Ko W, Rosengart T, Altorki N, Lang S, Gold JP, Krieger KH, Isom OW. Cost containment in cardiac surgery: results with a critical pathway for coronary bypass surgery at the New York hospital-Cornell Medical Center. Best Pract Benchmarking Healthc. 1996 Jan-Feb; 1(1):21-8.
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  97. Levy JH, Pifarre R, Schaff HV, Horrow JC, Albus R, Spiess B, Rosengart TK, Murray J, Clark RE, Smith P. A multicenter, double-blind, placebo-controlled trial of aprotinin for reducing blood loss and the requirement for donor-blood transfusion in patients undergoing repeat coronary artery bypass grafting. Circulation. 1995 Oct 15; 92(8):2236-44.
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  98. Zhang QX, Duenas M, Rosengart T. Effect of tumor necrosis factor-alpha on a cell line transformed by a secreted form of human fibroblast growth factor-1 gene and on its parental cell line. Cancer Lett. 1995 Feb 10; 89(1):49-54.
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  99. Munver R, Schulman IC, Wolf DJ, Rosengart TK. Heparin-induced thrombocytopenia and thrombosis: presentation after cardiopulmonary bypass. Ann Thorac Surg. 1994 Dec; 58(6):1764-6.
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  100. Rosengart TK, Helm RE, Klemperer J, Krieger KH, Isom OW. Combined aprotinin and erythropoietin use for blood conservation: results with Jehovah's Witnesses. Ann Thorac Surg. 1994 Nov; 58(5):1397-403.
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  101. Aldrich HR, Girardi L, Bush HL, Devereux RB, Rosengart TK. Recurrent systemic embolization caused by aortic thrombi. Ann Thorac Surg. 1994 Feb; 57(2):466-8.
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  102. Rosengart TK, Krieger K, Lang SJ, Gold JP, Altorki N, Roussel M, Debois WJ, Isom OW. Reoperative coronary artery bypass surgery. Improved preservation of myocardial function with retrograde cardioplegia. Circulation. 1993 Nov; 88(5 Pt 2):II330-5.
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  103. Rosengart TK. Risk analysis of primary versus reoperative coronary artery bypass grafting. Ann Thorac Surg. 1993 Nov; 56(5 Suppl):S74-7.
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  104. Helm RE, Gold JP, Rosengart TK, Zelano JA, Isom OW, Krieger KH. Erythropoietin in cardiac surgery. J Card Surg. 1993 Sep; 8(5):579-606.
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  105. Rosengart TK, Stark JF. Repair of atrial septal defect through a right thoracotomy. Ann Thorac Surg. 1993 May; 55(5):1138-40.
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  106. Rosengart TK, Redel DA, Stark JF. Surgical repair of aorto-right ventricular tunnel in an infant. Ann Thorac Surg. 1993 Feb; 55(2):520-2.
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  107. Isom OW, Rosengart TK. Percutaneous aortic valvuloplasty: off the bandwagon, again. J Am Coll Cardiol. 1992 Oct; 20(4):804-5.
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  108. Rosengart TK, Martini N, Ghosn P, Burt M. Multiple primary lung carcinomas: prognosis and treatment. Ann Thorac Surg. 1991 Oct; 52(4):773-8; discussion 778-9.
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  109. Rosengart TK, Rotterdam H, Ranson JH. Eosinophilic cholangitis: a self-limited cause of extrahepatic biliary obstruction. Am J Gastroenterol. 1990 May; 85(5):582-5.
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  110. Rosengart TK, Coppa GF. Abdominal mycobacterial infections in immunocompromised patients. Am J Surg. 1990 Jan; 159(1):125-31.
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  111. Kupferschmid JP, Rosengart TK, McIntosh CL, Leon MB, Clark RE. Amiodarone-induced complications after cardiac operation for obstructive hypertrophic cardiomyopathy. Ann Thorac Surg. 1989 Sep; 48(3):359-64.
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  112. Rosengart TK, Pass H, Cannon R, Miller DL, Solomon D, Clark RE. Ruptured gastroepiploic artery aneurysm and vascular collapse in a patient with thoracic aneurysm. J Cardiovasc Surg (Torino). 1989 May-Jun; 30(3):514-6.
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  113. Rosengart TK, Kuperschmid JP, Maciag T, Clark RE. Pharmacokinetics and distribution of heparin-binding growth factor I (endothelial cell growth factor) in the rat. Circ Res. 1989 Feb; 64(2):227-34.
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  114. Rosengart TK, Johnson WV, Friesel R, Clark R, Maciag T. Heparin protects heparin-binding growth factor-I from proteolytic inactivation in vitro. Biochem Biophys Res Commun. 1988 Apr 15; 152(1):432-40.
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  115. Rosengart TK, Kupferschmid JP, Ferrans VJ, Casscells W, Maciag T, Clark RE. Heparin-binding growth factor-I (endothelial cell growth factor) binds to endothelium in vivo. J Vasc Surg. 1988 Feb; 7(2):311-7.
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