Item Type | Name |
Academic Article
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Alterations of the retinoblastoma gene in clinically localized, stage B prostate adenocarcinomas.
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Academic Article
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FGF9 is an autocrine and paracrine prostatic growth factor expressed by prostatic stromal cells.
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Academic Article
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Mitogenic activation of human prostate-derived fibromuscular stromal cells by bradykinin.
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Academic Article
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Loss of heterozygosity on chromosomes 10 and 17 in clinically localized prostate carcinoma.
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Academic Article
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Chromosome 10 alterations in prostate adenocarcinoma (review).
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Academic Article
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Interleukin-8 is a paracrine inducer of fibroblast growth factor 2, a stromal and epithelial growth factor in benign prostatic hyperplasia.
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Academic Article
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Common mutations in BRCA1 and BRCA2 do not contribute to early prostate cancer in Jewish men.
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Academic Article
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Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer.
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Academic Article
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Endothelin-1 production and agonist activities in cultured prostate-derived cells: implications for regulation of endothelin bioactivity and bioavailability in prostatic hyperplasia.
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Academic Article
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Homozygous deletion of the PTEN tumor suppressor gene in a subset of prostate adenocarcinomas.
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Academic Article
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Alternative splicing of fibroblast growth factor receptors in human prostate cancer.
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Academic Article
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In vivo preservation of steroid specificity in CWR22 xenografts having a mutated androgen receptor.
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Academic Article
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Allelic loss on chromosome 13q in human prostate carcinoma.
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Academic Article
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Inactivation of the PTEN tumor suppressor gene is associated with increased angiogenesis in clinically localized prostate carcinoma.
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Academic Article
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Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression.
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Academic Article
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Role of fibroblast growth factor receptor signaling in prostate cancer cell survival.
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Academic Article
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RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer.
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Academic Article
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FGF17 is an autocrine prostatic epithelial growth factor and is upregulated in benign prostatic hyperplasia.
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Academic Article
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Androgen receptor mutations in prostate cancer.
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Academic Article
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The fibroblast growth factor receptor-4 Arg388 allele is associated with prostate cancer initiation and progression.
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Academic Article
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FGF-10 is expressed at low levels in the human prostate.
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Academic Article
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PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer.
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Academic Article
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Comparison of the growth-promoting effects of testosterone and 7-alpha-methyl-19-nor-testosterone (MENT) on the prostate and levator ani muscle of LPB-tag transgenic mice.
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Academic Article
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Sprouty4, a suppressor of tumor cell motility, is down regulated by DNA methylation in human prostate cancer.
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Academic Article
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Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation.
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Academic Article
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Increased expression of the metastasis-associated gene Ehm2 in prostate cancer.
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Academic Article
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Chronic activity of ectopic type 1 fibroblast growth factor receptor tyrosine kinase in prostate epithelium results in hyperplasia accompanied by intraepithelial neoplasia.
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Academic Article
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Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate.
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Academic Article
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Relaxin promotes prostate cancer progression.
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Academic Article
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Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition.
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Academic Article
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Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers.
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Academic Article
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Altered fibroblast growth factor receptor 4 stability promotes prostate cancer progression.
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Academic Article
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Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts.
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Academic Article
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The emerging role of the PI3-K-Akt pathway in prostate cancer progression.
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Academic Article
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Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice.
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Academic Article
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Interleukin-8 expression is increased in senescent prostatic epithelial cells and promotes the development of benign prostatic hyperplasia.
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Academic Article
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Multicenter clinical validation of PITX2 methylation as a prostate specific antigen recurrence predictor in patients with post-radical prostatectomy prostate cancer.
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Academic Article
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Role of SRC-1 in the promotion of prostate cancer cell growth and tumor progression.
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Academic Article
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The expression of Sprouty1, an inhibitor of fibroblast growth factor signal transduction, is decreased in human prostate cancer.
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Academic Article
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Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men.
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Academic Article
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Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer.
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Academic Article
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The alkylphospholipid, perifosine, radiosensitizes prostate cancer cells both in vitro and in vivo.
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Academic Article
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Mutation of the androgen receptor causes oncogenic transformation of the prostate.
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Academic Article
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The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase.
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Academic Article
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Increased expression and activity of CDC25C phosphatase and an alternatively spliced variant in prostate cancer.
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Academic Article
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Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis.
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Academic Article
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Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation.
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Academic Article
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SRC-3 is required for prostate cancer cell proliferation and survival.
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Academic Article
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Bystin in perineural invasion of prostate cancer.
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Academic Article
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CDC4 gene expression as potential biomarker for targeted therapy in prostate cancer.
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Academic Article
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Endocrine fibroblast growth factor FGF19 promotes prostate cancer progression.
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Academic Article
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Discovery and validation of 3 novel DNA methylation markers of prostate cancer prognosis.
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Academic Article
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Stromal antiapoptotic paracrine loop in perineural invasion of prostatic carcinoma.
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Academic Article
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Effects of dutasteride on prostate growth in the large probasin-large T antigen mouse model of prostate cancer.
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Academic Article
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Widespread deregulation of microRNA expression in human prostate cancer.
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Academic Article
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Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling.
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Academic Article
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Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death.
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Academic Article
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Bortezomib-mediated inhibition of steroid receptor coactivator-3 degradation leads to activated Akt.
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Academic Article
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Cancer-related axonogenesis and neurogenesis in prostate cancer.
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Academic Article
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DNA methylation and aberrant expression of Sprouty1 in human prostate cancer.
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Academic Article
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GGAP2/PIKE-a directly activates both the Akt and nuclear factor-kappaB pathways and promotes prostate cancer progression.
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Academic Article
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Genomic profiling of prostate cancers from African American men.
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Academic Article
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DNA methylation of the PITX2 gene promoter region is a strong independent prognostic marker of biochemical recurrence in patients with prostate cancer after radical prostatectomy.
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Academic Article
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Relaxin/RXFP1 signaling in prostate cancer progression.
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Academic Article
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Global gene expression analysis of reactive stroma in prostate cancer.
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Academic Article
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Dicer ablation impairs prostate stem cell activity and causes prostate atrophy.
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Academic Article
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The function of microRNAs, small but potent molecules, in human prostate cancer.
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Academic Article
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Recurrent chimeric RNAs enriched in human prostate cancer identified by deep sequencing.
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Academic Article
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Common structural and epigenetic changes in the genome of castration-resistant prostate cancer.
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Academic Article
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TGF-?1 induces an age-dependent inflammation of nerve ganglia and fibroplasia in the prostate gland stroma of a novel transgenic mouse.
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Academic Article
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Frequent heterogeneous missense mutations of GGAP2 in prostate cancer: implications for tumor biology, clonality and mutation analysis.
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Academic Article
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Role of TMPRSS2-ERG gene fusion in negative regulation of PSMA expression.
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Academic Article
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SULT2B1b sulfotransferase: induction by vitamin D receptor and reduced expression in prostate cancer.
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Academic Article
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Targeting fibroblast growth factor receptor signaling inhibits prostate cancer progression.
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Academic Article
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COUP-TFII inhibits TGF-?-induced growth barrier to promote prostate tumorigenesis.
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Academic Article
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Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2.
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Academic Article
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Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee.
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Academic Article
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Alterations in the p53 and MDM-2 genes are infrequent in clinically localized, stage B prostate adenocarcinomas.
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Academic Article
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Allelic loss on chromosome 10 in prostate adenocarcinoma.
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Academic Article
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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer.
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Academic Article
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Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer.
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Academic Article
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Elevated caveolin-1 levels in African-American versus white-American prostate cancer.
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Academic Article
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Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer.
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Academic Article
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Interleukin-6 is an autocrine growth factor in human prostate cancer.
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Academic Article
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The role of caveolin-1 in androgen insensitive prostate cancer.
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Academic Article
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Cellular senescence in the pathogenesis of benign prostatic hyperplasia.
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Academic Article
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Pathobiology of autochthonous prostate cancer in a pre-clinical transgenic mouse model.
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Academic Article
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Glutathione S-transferase pi is upregulated in the stromal compartment of hormone independent prostate cancer.
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Academic Article
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Fibroblast growth factor 2 promotes tumor progression in an autochthonous mouse model of prostate cancer.
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Academic Article
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Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee.
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Academic Article
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Growth and survival mechanisms associated with perineural invasion in prostate cancer.
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Academic Article
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The role of fibroblast growth factors and their receptors in prostate cancer.
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Academic Article
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Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer.
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Academic Article
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A working group classification of focal prostate atrophy lesions.
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Academic Article
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Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer.
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Academic Article
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Age-related DNA methylation changes in normal human prostate tissues.
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Academic Article
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Suppression of relaxin receptor RXFP1 decreases prostate cancer growth and metastasis.
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Academic Article
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Determining prostate cancer-specific death through quantification of stromogenic carcinoma area in prostatectomy specimens.
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Academic Article
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Associations between arachidonic acid metabolism gene polymorphisms and prostate cancer risk.
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Academic Article
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FGFR-4 Arg?88 enhances prostate cancer progression via extracellular signal-related kinase and serum response factor signaling.
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Academic Article
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Transcriptional and post-transcriptional regulation of Sprouty1, a receptor tyrosine kinase inhibitor in prostate cancer.
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Academic Article
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GLIPR1 tumor suppressor gene expressed by adenoviral vector as neoadjuvant intraprostatic injection for localized intermediate or high-risk prostate cancer preceding radical prostatectomy.
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Academic Article
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GLIPR1 suppresses prostate cancer development through targeted oncoprotein destruction.
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Academic Article
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Notch and TGF? form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity.
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Academic Article
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Development and clinical validation of a real-time PCR assay for PITX2 DNA methylation to predict prostate-specific antigen recurrence in prostate cancer patients following radical prostatectomy.
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Academic Article
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Biological correlates of biochemical recurrence free survival using multiple markers in a large tissue microarray cohort.
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Academic Article
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FGFR1 is essential for prostate cancer progression and metastasis.
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Concept
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Prostate
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Concept
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Prostate-Specific Antigen
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Academic Article
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ERK and AKT signaling drive MED1 overexpression in prostate cancer in association with elevated proliferation and tumorigenicity.
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Academic Article
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The steroid receptor coactivator-3 is required for the development of castration-resistant prostate cancer.
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Academic Article
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Identification of novel DNA-methylated genes that correlate with human prostate cancer and high-grade prostatic intraepithelial neoplasia.
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Academic Article
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Semaphorin 4F as a critical regulator of neuroepithelial interactions and a biomarker of aggressive prostate cancer.
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Academic Article
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Genes upregulated in prostate cancer reactive stroma promote prostate cancer progression in vivo.
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Academic Article
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Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin.
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Academic Article
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Two consecutive sets of transrectal ultrasound guided sextant biopsies of the prostate for the detection of prostate cancer.
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Academic Article
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Expression of fibroblast growth factors (FGFs) and FGF receptors in human prostate.
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Academic Article
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HLA-restricted NY-ESO-1 peptide immunotherapy for metastatic castration resistant prostate cancer.
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Academic Article
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FGFR1-WNT-TGF-? signaling in prostate cancer mouse models recapitulates human reactive stroma.
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Academic Article
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The senescence-associated secretory phenotype promotes benign prostatic hyperplasia.
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Academic Article
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A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis.
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Academic Article
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miR-1 and miR-133b are differentially expressed in patients with recurrent prostate cancer.
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Academic Article
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Increased Notch signalling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells.
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Academic Article
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The prostate cancer TMPRSS2:ERG fusion synergizes with the vitamin D receptor (VDR) to induce CYP24A1 expression-limiting VDR signaling.
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Academic Article
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Differential expression of stem cell markers and ABCG2 in recurrent prostate cancer.
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Academic Article
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Stromal TGF-? signaling induces AR activation in prostate cancer.
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Academic Article
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Androgens regulate prostate cancer cell growth via an AMPK-PGC-1a-mediated metabolic switch.
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Academic Article
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Identification of microRNAs differentially expressed in prostatic secretions of patients with prostate cancer.
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Academic Article
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Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression.
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Academic Article
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Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis.
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Academic Article
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Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis.
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Academic Article
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Genome-wide differentially methylated genes in prostate cancer tissues from African-American and Caucasian men.
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Academic Article
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Expression of ERG protein in prostate cancer: variability and biological correlates.
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Academic Article
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Overexpression of miR-145-5p inhibits proliferation of prostate cancer cells and reduces SOX2 expression.
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Academic Article
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FGF23 promotes prostate cancer progression.
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Academic Article
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Oxidative stress promotes benign prostatic hyperplasia.
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Academic Article
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The tumor suppressive miR-200b subfamily is an ERG target gene in human prostate tumors.
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Academic Article
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The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker.
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Academic Article
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Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer.
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Academic Article
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The role of ATP-binding cassette transporter genes in the progression of prostate cancer.
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Academic Article
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Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations.
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Academic Article
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Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer.
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Academic Article
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Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model.
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Academic Article
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Neuronal Trans-Differentiation in Prostate Cancer Cells.
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Academic Article
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Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer Progression.
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Academic Article
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Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor.
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Academic Article
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The essential role of GATA transcription factors in adult murine prostate.
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Academic Article
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Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer.
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Academic Article
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Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors.
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Academic Article
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Inhibition of FOXC2 restores epithelial phenotype and drug sensitivity in prostate cancer cells with stem-cell properties.
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Academic Article
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GRK3 is a direct target of CREB activation and regulates neuroendocrine differentiation of prostate cancer cells.
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Academic Article
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MNX1 Is Oncogenically Upregulated in African-American Prostate Cancer.
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Academic Article
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SPOP Mutation Drives Prostate Tumorigenesis In?Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling.
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Academic Article
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Cellular interactions of the phosphorylated form of AKT in prostate cancer.
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Academic Article
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SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein.
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Academic Article
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RET Signaling in Prostate Cancer.
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Academic Article
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RGS12 Is a Novel Tumor-Suppressor Gene in African American Prostate Cancer That Represses AKT and MNX1 Expression.
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Academic Article
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miR-33a is a tumor suppressor microRNA that is decreased in prostate cancer.
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Academic Article
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Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling.
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Academic Article
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Anatomy and Histology of the Human and Murine Prostate.
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Academic Article
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Influence of the neural microenvironment on prostate cancer.
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Academic Article
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TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis.
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Academic Article
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MicroRNAs as prognostic markers in prostate cancer.
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Academic Article
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Androgen deprivation promotes neuroendocrine differentiation and angiogenesis through CREB-EZH2-TSP1 pathway in prostate cancers.
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Grant
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Cellular Senescence in the Pathogenesis of Benign Prostatic Hyperplasia
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Grant
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Role of FGFR1 signaling in distinct cell lineages in prostate cancer progresssion
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Grant
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Mechanisms of Cytokine Induced Lower Urinary Track Pathology
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Grant
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A novel oncogenic axis in African American prostate cancer
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Grant
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SPORE in Prostate Cancer
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Grant
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Cytokines and FGFs in prostate cancer progression
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Grant
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ROLE OF FIBROBLAST GROWTH FACTORS IN PROSTATE GROWTH
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Academic Article
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Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms.
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Academic Article
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Comparative analysis of p16 expression among African American and European American prostate cancer patients.
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Academic Article
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Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer.
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Academic Article
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Methionine-Homocysteine Pathway in African-American Prostate Cancer.
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Academic Article
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ING5 inhibits cancer aggressiveness by inhibiting Akt and activating p53 in prostate cancer.
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Academic Article
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Targeting the TMPRSS2/ERG fusion mRNA using liposomal nanovectors enhances docetaxel treatment in prostate cancer.
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Academic Article
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Association of Genetic Ancestry With DNA Methylation Changes in Prostate Cancer Disparity.
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Academic Article
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Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer.
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Academic Article
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Gene fusion characterisation of rare aggressive prostate cancer variants-adenosquamous carcinoma, pleomorphic giant-cell carcinoma, and sarcomatoid carcinoma: an analysis of 19 cases.
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Academic Article
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Kallikrein gene family as biomarkers for recurrent prostate cancer.
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Academic Article
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Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling.
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Academic Article
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MAPK4 promotes prostate cancer by concerted activation of androgen receptor and AKT.
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Academic Article
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CASC11 promotes aggressiveness of prostate cancer cells through miR-145/IGF1R axis.
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Academic Article
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MEX3D is an oncogenic driver in prostate cancer.
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Academic Article
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CKB inhibits epithelial-mesenchymal transition and prostate cancer progression by sequestering and inhibiting AKT activation.
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Academic Article
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Expression of Endogenous Retroviral RNA in Prostate Tumors has Prognostic Value and Shows Differences among Americans of African Versus European/Middle Eastern Ancestry.
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Academic Article
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Racial disparities in prostate cancer: A complex interplay between socioeconomic inequities and genomics.
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Academic Article
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Repair-Assisted Damage Detection Reveals Biological Disparities in Prostate Cancer between African Americans and European Americans.
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Academic Article
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Development and validation of a quantitative reactive stroma biomarker (qRS) for prostate cancer prognosis.
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Academic Article
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Lipid Alterations in African American Men with Prostate Cancer.
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Academic Article
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Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer.
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Academic Article
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The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response.
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Academic Article
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Spatial Profiling of the Prostate Cancer Tumor Microenvironment Reveals Multiple Differences in Gene Expression and Correlation with Recurrence Risk.
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Academic Article
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Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer.
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Academic Article
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Persistent organic pollutants promote aggressiveness in prostate cancer.
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Academic Article
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Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity.
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Academic Article
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Role of adenosine deaminase in prostate cancer progression.
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Academic Article
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A west African ancestry-associated SNP on 8q24 predicts a positive biopsy in African American men with suspected prostate cancer following PSA screening.
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