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BOERWINKLE, ERIC

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Item Type	Name
Academic Article	Generalized T2 test for genome association studies.
Academic Article	Gene expression profiling and functional proteomic analysis reveal perturbed kinase-mediated signaling in genetic stroke susceptibility.
Academic Article	From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I.
Academic Article	Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: The Coronary Artery Risk Development in Young Adults (CARDIA) study.
Academic Article	Ethnic differences in peripheral arterial disease in the NHLBI Genetic Epidemiology Network of Arteriopathy (GENOA) study.
Academic Article	Multivariate linkage analysis of blood pressure and body mass index.
Academic Article	Autosomal genome-wide scan for coronary artery calcification loci in sibships at high risk for hypertension.
Academic Article	Low-density lipoprotein particle size and coronary atherosclerosis in subjects belonging to hypertensive sibships.
Academic Article	Lack of association between lipoprotein(a) and coronary artery calcification in the Genetic Epidemiology Network of Arteriopathy (GENOA) study.
Academic Article	Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies.
Academic Article	Relationship of blood pressure measures with coronary artery calcification.
Academic Article	Genetics of blood pressure, hypertensive complications, and antihypertensive drug responses.
Academic Article	Apolipoprotein E and progression of chronic kidney disease.
Academic Article	Genomic loci with pleiotropic effects on coronary artery calcification.
Academic Article	Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study.
Academic Article	Apolipoprotein E genotype and incident ischemic stroke: the Atherosclerosis Risk in Communities Study.
Academic Article	Relation of C-reactive protein and fibrinogen to coronary artery calcium in subjects with systemic hypertension.
Academic Article	A genome-wide linkage scan for ankle-brachial index in African American and non-Hispanic white subjects participating in the GENOA study.
Academic Article	Heritability of coronary artery calcium quantity measured by electron beam computed tomography in asymptomatic adults.
Academic Article	Sequence variation in the soluble epoxide hydrolase gene and subclinical coronary atherosclerosis: interaction with cigarette smoking.
Academic Article	Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants.
Academic Article	A scan statistic for identifying chromosomal patterns of SNP association.
Academic Article	From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II.
Academic Article	An entropy-based genome-wide transmission/disequilibrium test.
Academic Article	Interaction between soluble thrombomodulin and intercellular adhesion molecule-1 in predicting risk of coronary heart disease.
Academic Article	Diagnostic tools in linkage analysis for quantitative traits.
Academic Article	Interaction effects of high-density lipoprotein metabolism gene variation and alcohol consumption on coronary heart disease risk: the atherosclerosis risk in communities study.
Academic Article	Evaluating the context-dependent effect of family history of stroke in a genome scan for hypertension.
Academic Article	Risk of atherosclerosis: interaction of smoking and glutathione S-transferase genes.
Academic Article	Five common gene variants identify elevated genetic risk for coronary heart disease.
Academic Article	Regional association-based fine-mapping for sodium-lithium countertransport on chromosome 10.
Academic Article	beta2-adrenergic receptor polymorphism and venous thromboembolism.
Academic Article	Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease.
Academic Article	Investigating the complex genetic architecture of ankle-brachial index, a measure of peripheral arterial disease, in non-Hispanic whites.
Academic Article	Atherosclerosis Risk in Communities (ARIC) Carotid MRI flow cytometry study of monocyte and platelet markers: intraindividual variability and reliability.
Academic Article	Q192R polymorphism of the paraoxanase 1 gene and its association with serum lipoprotein variables and carotid artery intima-media thickness in young adults from a biracial community. The Bogalusa Heart Study.
Academic Article	Interactions between the single nucleotide polymorphisms in the homocysteine pathway (MTHFR 677C>T, MTHFR 1298 A>C, and CBSins) and the efficacy of HMG-CoA reductase inhibitors in preventing cardiovascular disease in high-risk patients of hypertension: the GenHAT study.
Academic Article	Genetically hypertensive Brown Norway congenic rat strains suggest intermediate traits underlying genetic hypertension.
Academic Article	Variation in ANGPTL4 and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study.
Academic Article	APOA5 polymorphisms influence plasma triglycerides in young, healthy African Americans and whites of the CARDIA Study.
Academic Article	Genomic susceptibility loci for brain atrophy in hypertensive sibships from the GENOA study.
Academic Article	Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population.
Academic Article	Antihypertensive pharmacogenetic effect of fibrinogen-beta variant -455G>A on cardiovascular disease, end-stage renal disease, and mortality: the GenHAT study.
Academic Article	The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study.
Academic Article	The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts.
Academic Article	Coronary heart disease risk, aspirin use, and apolipoprotein(a) 4399Met allele in the Atherosclerosis Risk in Communities (ARIC) study.
Academic Article	Autosomal genome scan for loci linked to blood pressure levels and trends since childhood: the Bogalusa Heart Study.
Academic Article	Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts.
Academic Article	Longitudinal association of PCSK9 sequence variations with low-density lipoprotein cholesterol levels: the Coronary Artery Risk Development in Young Adults Study.
Academic Article	Genome-wide association study of PR interval.
Academic Article	Hypertension in pregnancy as a risk factor for cardiovascular disease later in life.
Academic Article	Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study.
Academic Article	Associations of lipoprotein lipase gene polymorphisms with longitudinal plasma lipid trends in young adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study.
Academic Article	Carotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk: the ARIC (Atherosclerosis Risk In Communities) study.
Academic Article	Demographic, environmental, and genetic predictors of metabolic side effects of hydrochlorothiazide treatment in hypertensive subjects.
Academic Article	Ethnic and sex differences in the prevalence, treatment, and control of dyslipidemia among hypertensive adults in the GENOA study.
Academic Article	The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke.
Academic Article	Association of glycemic index and glycemic load with risk of incident coronary heart disease among Whites and African Americans with and without type 2 diabetes: the Atherosclerosis Risk in Communities study.
Academic Article	Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC Study.
Academic Article	Biological, clinical and population relevance of 95 loci for blood lipids.
Academic Article	The beta(2)-adrenergic receptor Arg16-gly polymorphism and interactions involving beta(2)- and beta(3)-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: the Bogalusa Heart Study.
Academic Article	Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
Academic Article	Plasma MCP-1 level and risk for peripheral arterial disease and incident coronary heart disease: Atherosclerosis Risk in Communities study.
Academic Article	Genetic variation of the renin-angiotensin system and chronic kidney disease progression in black individuals in the atherosclerosis risk in communities study.
Academic Article	Cardiac troponin T measured by a highly sensitive assay predicts coronary heart disease, heart failure, and mortality in the Atherosclerosis Risk in Communities Study.
Academic Article	Parental history of stroke and myocardial infarction predicts coronary artery calcification: The Coronary Artery Risk Development in Young Adults (CARDIA) study.
Academic Article	An updated meta-analysis of genome scans for hypertension and blood pressure in the NHLBI Family Blood Pressure Program (FBPP).
Academic Article	Pleiotropic genetic effects contribute to the correlation between HDL cholesterol, triglycerides, and LDL particle size in hypertensive sibships.
Academic Article	Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals.
Academic Article	Pharmacogenetics of response to statins: where do we stand?
Academic Article	Pharmacogenetic associations of MMP9 and MMP12 variants with cardiovascular disease in patients with hypertension.
Academic Article	Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.
Academic Article	Clan genomics and the complex architecture of human disease.
Academic Article	Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study.
Academic Article	Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.
Academic Article	Association of genetic variants and incident coronary heart disease in multiethnic cohorts: the PAGE study.
Academic Article	Contrasting multi-site genotypic distributions among discordant quantitative phenotypes: the APOA1/C3/A4/A5 gene cluster and cardiovascular disease risk factors.
Academic Article	Pharmacogenetic association of the angiotensin-converting enzyme insertion/deletion polymorphism on blood pressure and cardiovascular risk in relation to antihypertensive treatment: the Genetics of Hypertension-Associated Treatment (GenHAT) study.
Academic Article	The 9p21 genetic variant is additive to carotid intima media thickness and plaque in improving coronary heart disease risk prediction in white participants of the Atherosclerosis Risk in Communities (ARIC) Study.
Academic Article	African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts.
Academic Article	Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
Academic Article	P-selectin Thr715Pro polymorphism predicts P-selectin levels but not risk of incident coronary heart disease or ischemic stroke in a cohort of 14595 participants: the Atherosclerosis Risk in Communities Study.
Academic Article	The Centers for Mendelian Genomics: a new large-scale initiative to identify the genes underlying rare Mendelian conditions.
Academic Article	Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing.
Academic Article	NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: the Atherosclerosis Risk in Communities study.
Academic Article	Effect of 9p21 genetic variation on coronary heart disease is not modified by other risk markers. The Atherosclerosis Risk in Communities (ARIC) Study.
Academic Article	Multiple genes for essential-hypertension susceptibility on chromosome 1q.
Academic Article	Large-scale association analysis identifies new risk loci for coronary artery disease.
Academic Article	Genome-wide association study of retinopathy in individuals without diabetes.
Academic Article	Epistatic effects between two genes in the renin-angiotensin system and systolic blood pressure and coronary artery calcification.
Academic Article	Specific P-selectin and P-selectin glycoprotein ligand-1 genotypes/haplotypes are associated with risk of incident CHD and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study.
Academic Article	A common allele on chromosome 9 associated with coronary heart disease.
Academic Article	Evidence for consistent intragenic and intergenic interactions between SNP effects in the APOA1/C3/A4/A5 gene cluster.
Academic Article	Relevance of genetics and genomics for prevention and treatment of cardiovascular disease: a scientific statement from the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group.
Academic Article	A comparison of serum creatinine-based methods for identifying chronic kidney disease in hypertensive individuals and their siblings.
Academic Article	Consistent effects of genes involved in reverse cholesterol transport on plasma lipid and apolipoprotein levels in CARDIA participants.
Academic Article	Influence of genomic loci on measures of chronic kidney disease in hypertensive sibships.
Academic Article	Apolipoprotein E genotype and gallbladder disease risk in a large population-based cohort.
Academic Article	Family-based association study of matrix metalloproteinase-3 and -9 haplotypes with susceptibility to ischemic white matter injury.
Academic Article	A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease.
Academic Article	Increased risk of incident stroke associated with the cyclooxygenase 2 (COX-2) G-765C polymorphism in African-Americans: the Atherosclerosis Risk in Communities Study.
Academic Article	Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study.
Academic Article	Relation of PCSK9 mutations to serum low-density lipoprotein cholesterol in childhood and adulthood (from The Bogalusa Heart Study).
Academic Article	Interaction of G-protein beta3 subunit and nitric oxide synthase gene polymorphisms on carotid artery intima-media thickness in young adults: the Bogalusa Heart Study.
Academic Article	Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic.
Academic Article	Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies.
Academic Article	HFE C282Y homozygotes have reduced low-density lipoprotein cholesterol: the Atherosclerosis Risk in Communities (ARIC) Study.
Academic Article	Single nucleotide polymorphisms associated with coronary heart disease predict incident ischemic stroke in the atherosclerosis risk in communities study.
Academic Article	Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.
Academic Article	Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of type 2 diabetes in African American and Caucasian adults: the Atherosclerosis Risk in Communities study.
Academic Article	Genome-wide linkage analysis for uric acid in families enriched for hypertension.
Academic Article	The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study.
Academic Article	Admixture mapping of quantitative trait loci for blood lipids in African-Americans.
Academic Article	Ala54Thr polymorphism of the fatty acid binding protein 2 gene and saturated fat intake in relation to lipid levels and insulin resistance: the Coronary Artery Risk Development in Young Adults (CARDIA) study.
Academic Article	Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.
Academic Article	A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study.
Academic Article	Genomewide association studies of stroke.
Academic Article	NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.
Academic Article	Genomic susceptibility Loci for brain atrophy, ventricular volume, and leukoaraiosis in hypertensive sibships.
Academic Article	Admixture mapping of obesity-related traits in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study.
Academic Article	Variation in the checkpoint kinase 2 gene is associated with type 2 diabetes in multiple populations.
Academic Article	Impact of abdominal obesity on incidence of adverse metabolic effects associated with antihypertensive medications.
Academic Article	Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study.
Academic Article	Genome-wide identification of allelic expression in hypertensive rats.
Academic Article	Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the Atherosclerosis Risk in Communities study.
Academic Article	Use of wrapper algorithms coupled with a random forests classifier for variable selection in large-scale genomic association studies.
Academic Article	Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study.
Academic Article	Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.
Academic Article	Association of circulating matrix metalloproteinases with carotid artery characteristics: the Atherosclerosis Risk in Communities Carotid MRI Study.
Academic Article	Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium.
Academic Article	Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest.
Academic Article	New loci associated with kidney function and chronic kidney disease.
Academic Article	Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes.
Academic Article	Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study.
Academic Article	Independent susceptibility markers for atrial fibrillation on chromosome 4q25.
Academic Article	Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls.
Academic Article	Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.
Academic Article	Is low-grade serous ovarian cancer part of the tumor spectrum of hereditary breast and ovarian cancer?
Academic Article	Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients.
Academic Article	Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans.
Academic Article	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.
Academic Article	High-resolution identity by descent mapping uncovers the genetic basis for blood pressure differences between spontaneously hypertensive rat lines.
Academic Article	Oligogenic heterozygosity in individuals with high-functioning autism spectrum disorders.
Academic Article	Risk factor profile for chronic kidney disease is similar to risk factor profile for small artery disease.
Academic Article	Genome-wide association analysis of incident coronary heart disease (CHD) in African Americans: a short report.
Academic Article	Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Academic Article	Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
Academic Article	A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains.
Academic Article	Carotid arterial wall characteristics are associated with incident ischemic stroke but not coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) study.
Academic Article	Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.
Academic Article	Pharmacogenetic effect of the stromelysin (MMP3) polymorphism on stroke risk in relation to antihypertensive treatment: the genetics of hypertension associated treatment study.
Academic Article	Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study.
Academic Article	Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study.
Academic Article	Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.
Academic Article	Evolution and functional impact of rare coding variation from deep sequencing of human exomes.
Academic Article	Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.
Academic Article	Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
Academic Article	CUBN is a gene locus for albuminuria.
Academic Article	Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
Academic Article	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
Academic Article	PNPLA3 polymorphisms and liver aminotransferase levels in a Mexican American population.
Academic Article	Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.
Academic Article	Common variants at 6p21.1 are associated with large artery atherosclerotic stroke.
Academic Article	A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.
Academic Article	Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
Academic Article	Common carotid artery intima-media thickness is as good as carotid intima-media thickness of all carotid artery segments in improving prediction of coronary heart disease risk in the Atherosclerosis Risk in Communities (ARIC) study.
Academic Article	Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.
Academic Article	Fat mass and obesity gene and cognitive decline: the Atherosclerosis Risk in Communities Study.
Academic Article	A genome-wide association study of aging.
Academic Article	Matrix gla protein gene polymorphism is associated with increased coronary artery calcification progression.
Academic Article	Impact of genetic polymorphisms of SLC2A2, SLC2A5, and KHK on metabolic phenotypes in hypertensive individuals.
Academic Article	Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
Academic Article	Chromosome 9p21 single nucleotide polymorphisms are not associated with recurrent myocardial infarction in patients with established coronary artery disease.
Academic Article	Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium.
Academic Article	Patterns and rates of exonic de novo mutations in autism spectrum disorders.
Academic Article	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.
Academic Article	A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies.
Academic Article	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
Academic Article	Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.
Academic Article	Hypertension susceptibility loci and blood pressure response to antihypertensives: results from the pharmacogenomic evaluation of antihypertensive responses study.
Academic Article	Loci influencing blood pressure identified using a cardiovascular gene-centric array.
Academic Article	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.
Academic Article	LPL polymorphism predicts stroke risk in men.
Academic Article	Sequence polymorphism at the human apolipoprotein AII gene ( APOA2): unexpected deficit of variation in an African-American sample.
Academic Article	"Into thin air" and the genetics of complex traits.
Academic Article	The variable number of tandem repeat polymorphism of platelet glycoprotein Ibalpha and risk of coronary heart disease.
Academic Article	Positional identification of hypertension susceptibility genes on chromosome 2.
Academic Article	Nitric oxide synthase gene polymorphism (G894T) influences arterial stiffness in adults: The Bogalusa Heart Study.
Academic Article	Genetics of ultrasonographic carotid atherosclerosis.
Academic Article	Genetic discoveries and nursing implications for complex disease prevention and management.
Academic Article	Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.
Academic Article	Quantitative trait loci influencing low density lipoprotein particle size in African Americans.
Academic Article	An assessment of incremental coronary risk prediction using C-reactive protein and other novel risk markers: the atherosclerosis risk in communities study.
Academic Article	Absence of an interaction between the angiotensin-converting enzyme insertion-deletion polymorphism and pravastatin on cardiovascular disease in high-risk hypertensive patients: the Genetics of Hypertension-Associated Treatment (GenHAT) study.
Academic Article	A genome-wide linkage scan for diabetic retinopathy susceptibility genes in Mexican Americans with type 2 diabetes from Starr County, Texas.
Academic Article	Association of polymorphisms in NOS3 with the ankle-brachial index in hypertensive adults.
Academic Article	Personalized medicine for high blood pressure.
Academic Article	Replicating genotype-phenotype associations.
Academic Article	Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension.
Academic Article	Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study.
Academic Article	Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD.
Academic Article	Variation in PCSK9, low LDL cholesterol, and risk of peripheral arterial disease.
Academic Article	TCF7L2 variants associate with CKD progression and renal function in population-based cohorts.
Academic Article	Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies.
Academic Article	Inflammatory protein levels and depression screening after coronary stenting predict major adverse coronary events.
Academic Article	Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease.
Academic Article	Multiple loci associated with indices of renal function and chronic kidney disease.
Academic Article	Correlates of carotid plaque presence and composition as measured by MRI: the Atherosclerosis Risk in Communities Study.
Academic Article	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
Academic Article	Associations between dietary patterns and flow cytometry-measured biomarkers of inflammation and cellular activation in the Atherosclerosis Risk in Communities (ARIC) Carotid Artery MRI Study.
Academic Article	Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
Academic Article	Role of BMI in the Association of the TCF7L2 rs7903146 Variant with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Academic Article	Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Academic Article	Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
Academic Article	Association of the platelet GPIIb/IIIa polymorphism with atherosclerotic plaque morphology: the Atherosclerosis Risk in Communities (ARIC) Study.
Academic Article	Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
Academic Article	Relation of cholesterol and lipoprotein parameters with carotid artery plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) carotid MRI study.
Academic Article	Global DNA methylation and risk of subclinical atherosclerosis in young adults: the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study.
Academic Article	Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study.
Academic Article	Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies.
Academic Article	A genome-wide association search for type 2 diabetes genes in African Americans.
Academic Article	Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
Academic Article	G protein receptor kinase 4 polymorphisms: ?-blocker pharmacogenetics and treatment-related outcomes in hypertension.
Academic Article	Resequencing and clinical associations of the 9p21.3 region: a comprehensive investigation in the Framingham heart study.
Academic Article	Genetic predisposition to higher blood pressure increases coronary artery disease risk.
Academic Article	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Academic Article	Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls.
Concept	Autoimmune Diseases
Concept	Liver Diseases
Concept	Genetic Diseases, Inborn
Concept	Moyamoya Disease
Concept	Peripheral Vascular Diseases
Concept	Disease Models, Animal
Concept	Central Nervous System Diseases
Concept	Bone Diseases, Developmental
Concept	Pulmonary Disease, Chronic Obstructive
Concept	Brain Diseases
Concept	Communicable Diseases
Concept	Neurodegenerative Diseases
Concept	Disease-Free Survival
Concept	Chronic Disease
Concept	Disease Susceptibility
Concept	Hirschsprung Disease
Concept	Retinal Diseases
Concept	Coronary Disease
Concept	Alzheimer Disease
Concept	Arterial Occlusive Diseases
Concept	Immune System Diseases
Concept	Hypothalamic Diseases
Concept	Disease Progression
Concept	Kidney Diseases
Concept	Gallbladder Diseases
Concept	Periodontal Diseases
Concept	Coronary Artery Disease
Concept	Acute Disease
Concept	Crohn Disease
Concept	Infant, Newborn, Diseases
Concept	Disease Outbreaks
Concept	Genetic Predisposition to Disease
Concept	Nervous System Diseases
Concept	Cardiovascular Diseases
Concept	Charcot-Marie-Tooth Disease
Concept	Lung Diseases
Concept	Vascular Diseases
Concept	Carotid Artery Diseases
Concept	Autonomic Nervous System Diseases
Concept	Heart Diseases
Concept	Lung Diseases, Interstitial
Concept	Hematologic Diseases
Concept	Aortic Diseases
Concept	Disease
Concept	Peripheral Nervous System Diseases
Concept	Metabolic Diseases
Academic Article	Cardiovascular biomarkers and subclinical brain disease in the atherosclerosis risk in communities study.
Academic Article	APOL1 variants associate with increased risk of CKD among African Americans.
Academic Article	Associations between metabolomic compounds and incident heart failure among African Americans: the ARIC Study.
Academic Article	Ceruloplasmin and heart failure in the Atherosclerosis Risk in Communities study.
Academic Article	Single nucleotide polymorphisms in cholesteryl ester transfer protein gene and recurrent coronary heart disease or mortality in patients with established atherosclerosis.
Academic Article	Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
Academic Article	Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.
Academic Article	Fine Mapping and Identification of BMI Loci in African Americans.
Academic Article	Common variants associated with plasma triglycerides and risk for coronary artery disease.
Academic Article	Discovery and refinement of loci associated with lipid levels.
Academic Article	Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.
Academic Article	Common variants in Mendelian kidney disease genes and their association with renal function.
Academic Article	APOE modulates the correlation between triglycerides, cholesterol, and CHD through pleiotropy, and gene-by-gene interactions.
Academic Article	Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking.
Academic Article	Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study.
Academic Article	Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study.
Academic Article	Predicting stroke through genetic risk functions: the CHARGE Risk Score Project.
Academic Article	Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
Academic Article	An empirical comparison of meta-analysis and mega-analysis of individual participant data for identifying gene-environment interactions.
Academic Article	Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function.
Academic Article	Microcephaly, epilepsy, and neonatal diabetes due to compound heterozygous mutations in IER3IP1: insights into the natural history of a rare disorder.
Academic Article	Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program.
Academic Article	Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.
Academic Article	Loss-of-function mutations in APOC3, triglycerides, and coronary disease.
Academic Article	Following-up genome-wide association study signals: lessons learned from Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
Academic Article	Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
Academic Article	Sequence variation in TMEM18 in association with body mass index: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
Academic Article	Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.
Academic Article	Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
Academic Article	PGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia.
Academic Article	Pleiotropic genes for metabolic syndrome and inflammation.
Academic Article	Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.
Academic Article	Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index.
Academic Article	Role of metabolic genes in blood arsenic concentrations of Jamaican children with and without autism spectrum disorder.
Academic Article	Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study.
Academic Article	A framework for the interpretation of de novo mutation in human disease.
Academic Article	Evaluation of microarray-based DNA methylation measurement using technical replicates: the Atherosclerosis Risk In Communities (ARIC) Study.
Academic Article	A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases.
Academic Article	The effects of angiotensinogen gene polymorphisms on cardiovascular disease outcomes during antihypertensive treatment in the GenHAT study.
Academic Article	Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
Academic Article	Association of exome sequences with plasma C-reactive protein levels in >9000 participants.
Academic Article	Molecular findings among patients referred for clinical whole-exome sequencing.
Academic Article	High-sensitivity troponin T and cardiovascular events in systolic blood pressure categories: atherosclerosis risk in communities study.
Academic Article	Association of sickle cell trait with chronic kidney disease and albuminuria in African Americans.
Academic Article	Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.
Academic Article	Gene-environment interplay in common complex diseases: forging an integrative model?recommendations from an NIH workshop.
Academic Article	Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Academic Article	New mutations in the RAB28 gene in 2 Spanish families with cone-rod dystrophy.
Academic Article	Inactivating mutations in NPC1L1 and protection from coronary heart disease.
Academic Article	Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.
Academic Article	Variants for HDL-C, LDL-C, and triglycerides identified from admixture mapping and fine-mapping analysis in African American families.
Academic Article	Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease.
Academic Article	Coronary heart disease and genetic variants with low phospholipase A2 activity.
Academic Article	Genetic overlap between diagnostic subtypes of ischemic stroke.
Academic Article	Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.
Academic Article	Genetic studies of body mass index yield new insights for obesity biology.
Academic Article	Strategic transformation of population studies: recommendations of the working group on epidemiology and population sciences from the National Heart, Lung, and Blood Advisory Council and Board of External Experts.
Academic Article	PLD3 variants in population studies.
Academic Article	PacBio-LITS: a large-insert targeted sequencing method for characterization of human disease-associated chromosomal structural variations.
Academic Article	COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis.
Academic Article	Analysis of loss-of-function variants and 20 risk factor phenotypes in 8,554 individuals identifies loci influencing chronic disease.
Academic Article	Loss of Function Mutations in NNT Are Associated With Left Ventricular Noncompaction.
Academic Article	Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study.
Academic Article	Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk.
Academic Article	Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study.
Academic Article	Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study.
Academic Article	Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC).
Academic Article	The Genetic Basis of Mendelian Phenotypes: Discoveries, Challenges, and Opportunities.
Academic Article	Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study.
Academic Article	Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy.
Academic Article	Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
Academic Article	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
Academic Article	Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.
Academic Article	Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.
Academic Article	Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease.
Academic Article	Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Academic Article	Whole-Exome Sequencing in Familial Parkinson Disease.
Academic Article	The impact of multiple single day blood pressure readings on cardiovascular risk estimation: The Atherosclerosis Risk in Communities study.
Academic Article	Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.
Academic Article	Molecular diagnostic experience of whole-exome sequencing in adult patients.
Academic Article	FLAGS: A Flexible and Adaptive Association Test for Gene Sets Using Summary Statistics.
Academic Article	Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data.
Academic Article	Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
Academic Article	Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium.
Academic Article	Associations Between the Serum Metabolome and All-Cause Mortality Among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study.
Academic Article	Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia.
Academic Article	Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure.
Academic Article	Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies.
Academic Article	A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.
Academic Article	PEHO Syndrome May Represent Phenotypic Expansion at the Severe End of the Early-Onset Encephalopathies.
Academic Article	Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.
Academic Article	A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration.
Academic Article	Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study.
Academic Article	Exome sequencing in mostly consanguineous Arab families with neurologic disease provides a high potential molecular diagnosis rate.
Academic Article	A Causal Network Analysis of the Fatty Acid Metabolome in African-Americans Reveals a Critical Role for Palmitoleate and Margarate.
Academic Article	A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
Academic Article	Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections.
Academic Article	Whole Exome Sequencing in Atrial Fibrillation.
Academic Article	Recurrent De Novo and Biallelic Variation of ATAD3A, Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes.
Academic Article	Biomarkers and degree of atherosclerosis are independently associated with incident atherosclerotic cardiovascular disease in a primary prevention cohort: The ARIC study.
Academic Article	Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders.
Academic Article	Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study.
Academic Article	Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.
Academic Article	Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles.
Academic Article	Association between high-sensitivity troponin T and cardiovascular risk in individuals with and without metabolic syndrome: The ARIC study.
Academic Article	DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.
Academic Article	Resolution of Disease Phenotypes Resulting from Multilocus Genomic Variation.
Academic Article	The performance of deleteriousness prediction scores for rare non-protein-changing single nucleotide variants in human genes.
Academic Article	Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities).
Academic Article	Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach.
Academic Article	Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease.
Academic Article	Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.
Academic Article	Genome-Wide Association of Copy Number Polymorphisms and Kidney Function.
Academic Article	Homozygous and hemizygous CNV detection from exome sequencing data in a Mendelian disease cohort.
Academic Article	Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation.
Academic Article	An NPPB Promoter Polymorphism Associated With Elevated N-Terminal pro-B-Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality.
Academic Article	Lessons learned from additional research analyses of unsolved clinical exome cases.
Academic Article	ANGPTL3 Deficiency and Protection Against Coronary Artery Disease.
Academic Article	Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.
Academic Article	Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.
Academic Article	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
Academic Article	Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.
Academic Article	Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism.
Academic Article	Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.
Academic Article	Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Academic Article	MicroRNAs in the miR-17 and miR-15 families are downregulated in chronic kidney disease with hypertension.
Academic Article	Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence.
Academic Article	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
Academic Article	Association of Mitochondrial DNA Copy Number With Cardiovascular Disease.
Academic Article	Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium.
Academic Article	Lipoprotein-associated phospholipase A2 and risk of incident peripheral arterial disease: Findings from The Atherosclerosis Risk in Communities study (ARIC).
Academic Article	Maternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children.
Academic Article	Prospective Study of Epigenetic Age Acceleration and Incidence of Cardiovascular Disease Outcomes in the ARIC Study (Atherosclerosis Risk in Communities).
Academic Article	Association between mitochondrial DNA copy number and sudden cardiac death: findings from the Atherosclerosis Risk in Communities study (ARIC).
Academic Article	Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.
Academic Article	Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population.
Academic Article	Epigenome-wide association studies identify DNA methylation associated with kidney function.
Academic Article	Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels.
Academic Article	Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.
Academic Article	Whole-genome sequencing study of serum peptide levels: the Atherosclerosis Risk in Communities study.
Academic Article	Exome-wide association study of plasma lipids in >300,000 individuals.
Academic Article	Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.
Academic Article	Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
Academic Article	CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis.
Academic Article	Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study.
Academic Article	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
Academic Article	Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk.
Academic Article	Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
Academic Article	Multi-ethnic genome-wide association study for atrial fibrillation.
Academic Article	Remnant-Like Particle Cholesterol, Low-Density Lipoprotein Triglycerides, and Incident Cardiovascular Disease.
Academic Article	Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
Academic Article	Contributions of rare coding variants in hypotension syndrome genes to population blood pressure variation.
Academic Article	Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels.
Academic Article	Identifying Genes Whose Mutant Transcripts Cause Dominant Disease Traits by Potential Gain-of-Function Alleles.
Academic Article	Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Academic Article	GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.
Academic Article	Insights into genetics, human biology and disease gleaned from family based genomic studies.
Academic Article	Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease.
Academic Article	HFE H63D Polymorphism and the Risk for Systemic Hypertension, Myocardial Remodeling, and Adverse Cardiovascular Events in the ARIC Study.
Academic Article	Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.
Academic Article	A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
Academic Article	Associations between SLC16A11 variants and diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
Academic Article	Association of monocyte myeloperoxidase with incident cardiovascular disease: The Atherosclerosis Risk in Communities Study.
Academic Article	Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation.
Academic Article	Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study.
Grant	An Integrated Genetic and Epigenetic Approach to Cerebral Small Vessel Disease
Grant	EPIDEMIOLOGY OF GENOTYPE BY ENVIRONMENT INTERACTION
Grant	Gene-environment interaction in complex disease
Grant	Genome-Wide Association for Loci Influencing CHD and Other Heart, Lung and Blood
Grant	MOLECULAR EPIDEMIOLOGY OF ESSENTIAL HYPERTENSION
Grant	Epigenetics of Successful Aging
Grant	FUNCTIONAL GENOMICS OF ARTERIAL THROMBOSIS
Grant	Building on GWAS for NHLBI-disease: the CHARGE consortium
Grant	Genetics of Hypertension Associated Treatment "GenHAT"
Grant	GWA for Gene-Environment Interaction Effects Influencing CHD
Grant	Modeling DNA Diversity in Reverse Cholesterol Transport
Grant	EPIDEMIOLOGY OF GENETIC FACTORS IN LIPID METABOLISM
Grant	Sequence-based Discovery of AD Risk & Protective Alleles
Grant	Therapeutic target discovery in ADSP data via comprehensive whole-genome analysis incorporating ethnic diversity and systems approaches
Grant	The Baylor-Hopkins Clinical Genomics Center for All of Us
Grant	MOLECULAR EPIDEMIOLOGY OF ESSENTIAL HYPERTENSION
Academic Article	ACAT: A Fast and Powerful p Value Combination Method for Rare-Variant Analysis in Sequencing Studies.
Academic Article	Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects.
Academic Article	Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project.
Academic Article	Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A?, tau, immunity and lipid processing.
Academic Article	Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
Academic Article	Subsequent Event Risk in Individuals With Established Coronary Heart Disease.
Academic Article	Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.
Academic Article	High-Sensitivity Troponin I and Incident Coronary Events, Stroke, Heart Failure Hospitalization, and Mortality in the ARIC Study.
Academic Article	Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease.
Concept	Asymptomatic Diseases
Concept	Peripheral Arterial Disease
Concept	Cerebral Small Vessel Diseases
Concept	Non-alcoholic Fatty Liver Disease
Academic Article	Metabolomic Pattern Predicts Incident Coronary Heart Disease.
Academic Article	A catalog of genetic loci associated with kidney function from analyses of a million individuals.
Academic Article	Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study.
Academic Article	APOL1 Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis.
Academic Article	Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A?, tau, immunity and lipid processing.
Academic Article	Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease.
Academic Article	Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
Academic Article	Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
Academic Article	A Genocentric Approach to Discovery of Mendelian Disorders.
Academic Article	A diagnostic ceiling for exome sequencing in cerebellar ataxia and related neurological disorders.
Academic Article	GSTM1 Deletion Exaggerates Kidney Injury in Experimental Mouse Models and Confers the Protective Effect of Cruciferous Vegetables in Mice and Humans.
Academic Article	Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.
Academic Article	Wolff-Parkinson-White syndrome: De novo variants and evidence for mutational burden in genes associated with atrial fibrillation.
Academic Article	Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.
Academic Article	Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease.
Academic Article	Levels and Change in Galectin-3 and Association With Cardiovascular Events: The ARIC Study.
Academic Article	Molecular Signature of Multisystem Cardiometabolic Stress and Its Association With Prognosis.
Academic Article	Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women.
Academic Article	Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.
Academic Article	Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems.
Academic Article	Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs.
Academic Article	A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos.
Academic Article	Inherited causes of clonal haematopoiesis in 97,691 whole genomes.
Academic Article	Alternative genomic diagnoses for individuals with a clinical diagnosis of Dubowitz syndrome.
Academic Article	Associations Between Carotid Artery Plaque Burden, Plaque Characteristics, and Cardiovascular Events: The ARIC Carotid Magnetic Resonance Imaging Study.
Academic Article	Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Academic Article	Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.
Academic Article	Cerebral small vessel disease genomics and its implications across the lifespan.
Academic Article	Germline Cancer Predisposition Variants in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group.
Academic Article	NAT8 Variants, N-Acetylated Amino Acids, and Progression of CKD.
Academic Article	Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium.
Academic Article	Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.
Academic Article	Genome-wide association study of circulating interleukin 6 levels identifies novel loci.
Academic Article	Dietary factors, gut microbiota, and serum trimethylamine-N-oxide associated with cardiovascular disease in the Hispanic Community Health Study/Study of Latinos.
Academic Article	Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality.
Academic Article	Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer's disease etiopathogenesis.
Academic Article	Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices.
Academic Article	Plasma amyloid ? levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants.
Academic Article	Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
Academic Article	Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.
Academic Article	Exome sequence association study of levels and longitudinal change of cardiovascular risk factor phenotypes in European Americans and African Americans from the Atherosclerosis Risk in Communities Study.
Academic Article	Genetic susceptibility, obesity and lifetime risk of type 2 diabetes: The ARIC study and Rotterdam Study.
Academic Article	Metabolomics of Dietary Acid Load and Incident Chronic Kidney Disease.
Academic Article	Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis.
Academic Article	Genetic testing in ambulatory cardiology clinics reveals high rate of findings with clinical management implications.
Academic Article	Genetic insights into biological mechanisms governing human ovarian ageing.
Academic Article	Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program.
Academic Article	Epidemiologic and Genetic Associations of Erythropoietin With Blood Pressure, Hypertension, and Coronary Artery Disease.
Grant	ImplementatioN ScIence for Genomic Health Translation (INSIGHT)
Academic Article	Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.
Academic Article	Metabolites Associated with Coffee Consumption and Incident Chronic Kidney Disease.
Academic Article	Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes.
Academic Article	Apolipoprotein E Polymorphism, Cardiac Remodeling, and Heart Failure in the ARIC Study.
Academic Article	Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease.
Academic Article	Serum metabolomic signatures of plant-based diets and incident chronic kidney disease.
Academic Article	Association of mitochondrial DNA copy number with cardiometabolic diseases.
Academic Article	Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts.
Academic Article	American Heart Association's Life's Simple 7: Lifestyle Recommendations, Polygenic Risk, and Lifetime Risk of Coronary Heart Disease.
Academic Article	Rare coding variants in RCN3 are associated with blood pressure.
Academic Article	Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits.
Academic Article	Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels.
Academic Article	New insights into the genetic etiology of Alzheimer's disease and related dementias.
Academic Article	Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases.
Academic Article	Genome-Wide Causation Studies of Complex Diseases.
Academic Article	APOL1 Kidney Risk Variants and Proteomics.
Academic Article	Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies.
Academic Article	DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases.
Academic Article	Midlife determinants of healthy cardiovascular aging: The Atherosclerosis Risk in Communities (ARIC) study.
Academic Article	Genetic Risk, Midlife Life's Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study.
Academic Article	Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data.
Academic Article	Polygenic Risk, Midlife Life's Simple 7, and Lifetime Risk of Stroke.
Academic Article	Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes.
Academic Article	Integrated proteomic and metabolomic modules identified as biomarkers of mortality in the Atherosclerosis Risk in Communities study and the African American Study of Kidney Disease?and Hypertension.
Academic Article	Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes.
Academic Article	Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease.
Academic Article	Patient and Clinician Perceptions of Precision Cardiology Care: Findings From the HeartCare Study.
Academic Article	Whole-exome sequencing study identifies four novel gene loci associated with diabetic kidney disease.
Academic Article	Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants.
Academic Article	Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease.
Academic Article	Genetic diversity fuels gene discovery for tobacco and alcohol use.
Academic Article	Case growth analysis to inform local response to COVID-19 epidemic in a diverse U.S community.
Academic Article	Association of Rare Protein-Truncating DNA Variants in APOB or PCSK9 With Low-density Lipoprotein Cholesterol Level and Risk of Coronary Heart Disease.
Academic Article	Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
Academic Article	Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts.
Academic Article	Whole Genome Analysis of Venous Thromboembolism: the Trans-Omics for Precision Medicine Program.
Academic Article	The genomic landscape of familial glioma.
Academic Article	Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia risk.
Academic Article	Clonal haematopoiesis and risk of chronic liver disease.
Academic Article	Metabolomic Signatures of Sedentary Behavior and Cardiometabolic Traits in US Hispanics/Latinos: Results from HCHS/SOL.
Academic Article	Association of Severe Hypercholesterolemia and Familial Hypercholesterolemia Genotype With Risk of Coronary Heart Disease.
Academic Article	Author Correction: Clonal haematopoiesis and risk of chronic liver disease.
Academic Article	Epigenome-wide association study using peripheral blood leukocytes identifies genomic regions associated with periodontal disease and edentulism in the Atherosclerosis Risk in Communities study.
Academic Article	Ancestry-driven metabolite variation provides insights into disease states in admixed populations.
Academic Article	Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life.
Academic Article	Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project.
Academic Article	Key variants via Alzheimer's Disease Sequencing Project whole genome sequence data.
Academic Article	Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk.
Academic Article	Wastewater sequencing reveals community and variant dynamics of the collective human virome.
Academic Article	Frequency of Variants in Mendelian Alzheimer's Disease Genes within the Alzheimer's Disease Sequencing Project (ADSP).
Academic Article	Wastewater analysis of Mpox virus in a city with low prevalence of Mpox disease: an environmental surveillance study.
Academic Article	A polygenic risk score of atrial fibrillation improves prediction of lifetime risk for heart failure.
Academic Article	Familial Hypercholesterolemia Variant and Cardiovascular Risk in Individuals With Elevated Cholesterol.
Academic Article	Key variants via the Alzheimer's Disease Sequencing Project whole genome sequence data.

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