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ROSEN, JEFFREY

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Item Type	Name
Academic Article	Isolation and characterization of milk protein nuclear RNAs in rat mammary gland.
Academic Article	Regulatory sequences involved in the hormonal control of casein gene expression.
Academic Article	Detection of casein messenger RNA in hormone-dependent mammary cancer by molecular hybridisation.
Academic Article	Evolution of the casein multigene family: conserved sequences in the 5' flanking and exon regions.
Academic Article	Multihormonal regulation of milk protein gene expression.
Academic Article	Use of a specific probe for ovalbumin messenger RNA to quantitate estrogen-induced gene transcripts.
Academic Article	Inhibitory effect of cortisol in vitro on 2-deoxyglucose uptake and RNA and protein metabolism in lymphosarcoma P1798.
Academic Article	Inhibition of glucose uptake in lymphosarcoma P1798 by cortisol and its relationship to the biosynthesis of deoxyribonucleic acid.
Academic Article	Effects of cortisol on DNA metabolism in the sensitive and resistant lines of mouse lymphoma P1798.
Academic Article	A comparison of the effect of glucocorticoids on glucose uptake and hexokinase activity in lymphosarcoma P1798.
Academic Article	Quantitation of casein messenger ribonucleic acid sequences using a specific complementary DNA hybridization probe.
Academic Article	Prolactin-mediated transcriptional and post-transcriptional control of casein gene expression.
Academic Article	Tumor-specific polyadenylated RNA's from 7,12-dimethylbenz(a)anthracene-induced mammary tumors revealed through hybridization with fractionated single-copy DNA.
Academic Article	Prolactin regulation of casein gene expression: possible mediators.
Academic Article	The rat casein multigene family. I. Fine structure of the gamma-casein gene.
Academic Article	The rat casein multigene family. Fine structure and evolution of the beta-casein gene.
Academic Article	Effect of estrogen on gene expression in the chick oviduct. 3. Hybridization studies with (3H) messenger RNA and (3H) complementary DNA under conditions of DNA excess.
Academic Article	Use of Sepharose 4B for preparative scale fractionation of eukaryotic messenger RNA's.
Academic Article	Comparative sequence analysis of the mRNAs coding for mouse and rat whey protein.
Academic Article	Multihormonal regulation of casein gene expression at the transcriptional and posttransciptional levels in the mammary gland.
Academic Article	Effect of estrogen on gene expression in the chick oviduct. I. Deoxyribonucleic acid--deoxyribonucleic acid renaturation studies.
Academic Article	Effect of estrogen on gene expression in the chick oviduct. II. Transcription of chick tritiated unique deoxyribonucleic acid as measured by hybridization in ribonucleic acid excess.
Academic Article	Prolactin induction of casein mRNA in organ culture. A model system for studying peptide hormone regulation of gene expression.
Academic Article	Gene expression in normal and neoplastic mammary tissue.
Academic Article	Isolation and characterization of casein-producing and -nonproducing cell populations from 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinomas.
Academic Article	Restriction enzyme mapping and heteroduplex analysis of the rat milk protein cDNA clones.
Academic Article	Sequence of rat alpha- and gamma-casein mRNAs: evolutionary comparison of the calcium-dependent rat casein multigene family.
Academic Article	Rat beta casein cDNA: sequence analysis and evolutionary comparisons.
Academic Article	Hormonal induction of casein gene expression limited to a small subpopulation of 7,12-dimethylbenz(a)anthracene-induced mammary tumor cells.
Academic Article	Complex hormonal regulation of rat casein gene expression.
Academic Article	Localization of the casein gene family to a single mouse chromosome.
Academic Article	Construction and preliminary characterization of the rat casein and alpha-lactalbumin cDNA clones.
Academic Article	Preparation and preliminary characterization of purified ovalbumin messenger RNA from the hen oviduct.
Academic Article	Regulation of casein messenger RNA during the development of the rat mammary gland.
Academic Article	Difference between mammary epithelial cells from mature virgin and primiparous mice.
Academic Article	Effect of estrogen on the synthesis and processing of ovalbumin messenger RNA in the chick oviduct.
Academic Article	Jak2 is an essential tyrosine kinase involved in pregnancy-mediated development of mammary secretory epithelium.
Academic Article	Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland.
Academic Article	neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice.
Academic Article	Composite response elements mediate hormonal and developmental regulation of milk protein gene expression.
Academic Article	Mechanisms of hormonal prevention of breast cancer.
Academic Article	Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium.
Academic Article	An inducible system for the study of FGF signalling in early amphibian development.
Academic Article	Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation.
Academic Article	Prostate-specific expression of p53(R172L) differentially regulates p21, Bax, and mdm2 to inhibit prostate cancer progression and prolong survival.
Academic Article	Distinct roles of fibroblast growth factor receptor 1 and 2 in regulating cell survival and epithelial-mesenchymal transition.
Academic Article	Hormone dependence in premalignant mammary progression.
Academic Article	p190-B RhoGAP regulates mammary ductal morphogenesis.
Academic Article	Identification of tumor-initiating cells in a p53-null mouse model of breast cancer.
Academic Article	Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice.
Academic Article	Lactogenic hormonal induction of long distance interactions between beta-casein gene regulatory elements.
Academic Article	Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression.
Academic Article	CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland.
Academic Article	Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice.
Academic Article	The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo.
Academic Article	Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential.
Academic Article	Progesterone receptor directly inhibits ?-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications.
Academic Article	Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis.
Academic Article	Processing of nuclear heterogeneous RNA: recent developments.
Academic Article	Noncoding RNAs involved in mammary gland development and tumorigenesis: there's a long way to go.
Academic Article	Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells.
Academic Article	On murine mammary epithelial stem cells: discovery, function, and current status.
Academic Article	Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation.
Academic Article	Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model.
Academic Article	WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells.
Academic Article	P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland.
Academic Article	FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer.
Academic Article	Integration of prolactin and glucocorticoid signaling at the beta-casein promoter and enhancer by ordered recruitment of specific transcription factors and chromatin modifiers.
Academic Article	Mammary tumour virus and casein gene transcription during mouse mammary development.
Academic Article	Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development.
Academic Article	Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line.
Academic Article	Fibroblast growth factor receptor 1-transformed mammary epithelial cells are dependent on RSK activity for growth and survival.
Academic Article	The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis.
Academic Article	An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ.
Academic Article	A putative role for microRNA-205 in mammary epithelial cell progenitors.
Academic Article	Chk1 haploinsufficiency results in anemia and defective erythropoiesis.
Academic Article	The ups and downs of miR-205: identifying the roles of miR-205 in mammary gland development and breast cancer.
Academic Article	Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer.
Academic Article	Genetic manipulation of individual somatic mammary cells in vivo reveals a master role of STAT5a in inducing alveolar fate commitment and lactogenesis even in the absence of ovarian hormones.
Academic Article	Wnt and mammary stem cells: hormones cannot fly wingless.
Academic Article	P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis.
Academic Article	Fibroblast growth factor receptor signaling is essential for normal mammary gland development and stem cell function.
Academic Article	P190A RhoGAP is required for mammary gland development.
Academic Article	On hormone action in the mammary gland.
Academic Article	Targeting CreER(T2) expression to keratin 8-expressing murine simple epithelia using bacterial artificial chromosome transgenesis.
Academic Article	Separation by cell size enriches for mammary stem cell repopulation activity.
Academic Article	Progesterone-mediated inhibition of casein mRNA and polysomal casein synthesis in the rat mammary gland during pregnancy.
Academic Article	Comparative biochemical studies of adriamycin and daunomycin in leukemic cells.
Academic Article	Comparison of the whey acidic protein genes of the rat and mouse.
Academic Article	Tissue- and cell-specific casein gene expression. II. Relationship to site-specific DNA methylation.
Academic Article	Isolation and characterization of purified rat casein messenger ribonucleic acids.
Academic Article	A transgenic mouse model for mammary carcinogenesis.
Academic Article	Use of PRKO mice to study the role of progesterone in mammary gland development.
Academic Article	A beta-catenin survival signal is required for normal lobular development in the mammary gland.
Academic Article	Multispecies comparative analysis of a mammalian-specific genomic domain encoding secretory proteins.
Academic Article	Isolation and characterization of functional mammary gland stem cells.
Academic Article	Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.
Academic Article	Chk1 is haploinsufficient for multiple functions critical to tumor suppression.
Academic Article	Transcriptional profiling of mammary gland side population cells.
Academic Article	A noncoding RNA is a potential marker of cell fate during mammary gland development.
Academic Article	A critical role for the inflammatory response in a mouse model of preneoplastic progression.
Academic Article	Keratin 6 is not essential for mammary gland development.
Academic Article	Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation.
Academic Article	Selective targeting of radiation-resistant tumor-initiating cells.
Academic Article	The epigenetic landscape of mammary gland development and functional differentiation.
Academic Article	Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer.
Academic Article	Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy.
Academic Article	Early-onset aging and defective DNA damage response in Cdc14b-deficient mice.
Academic Article	Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened.
Academic Article	Identification and gene expression profiling of tumor-initiating cells isolated from human osteosarcoma cell lines in an orthotopic mouse model.
Academic Article	Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells.
Academic Article	Stem cell antigen-1 (sca-1) regulates mammary tumor development and cell migration.
Concept	Mammary Glands, Animal
Concept	Pregnancy, Animal
Concept	Disease Models, Animal
Concept	Animals, Newborn
Concept	Mammary Neoplasms, Animal
Concept	Animals
Concept	Animals, Genetically Modified
Academic Article	Predicting drug responsiveness in human cancers using genetically engineered mice.
Academic Article	Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties.
Academic Article	Chking and executing cell division to prevent genomic instability.
Academic Article	Plk2 regulates mitotic spindle orientation and mammary gland development.
Academic Article	Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer.
Academic Article	Pygopus 2: tilting the Wnt-Notch balance in mammary epithelial lineage determination.
Academic Article	Paracrine signaling in mammary gland development: what can we learn about intratumoral heterogeneity?
Academic Article	STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer.
Academic Article	Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.
Academic Article	The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor.
Academic Article	Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium.
Academic Article	Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential.
Academic Article	Intratumoral heterogeneity in a Trp53-null mouse model of human breast cancer.
Academic Article	On mammary stem cells.
Academic Article	The increasing complexity of the cancer stem cell paradigm.
Academic Article	Modelling breast cancer: one size does not fit all.
Academic Article	Stop! In the name of transforming growth factor-beta: keeping estrogen receptor-alpha-positive mammary epithelial cells from proliferating.
Academic Article	Stem/progenitor cells in mouse mammary gland development and breast cancer.
Academic Article	Chk1 versus Cdc25: chking one's levels of cellular proliferation.
Academic Article	Will cancer stem cells provide new therapeutic targets?
Academic Article	The role of C/EBPbeta in mammary gland development and breast cancer.
Academic Article	Transcription factors.
Academic Article	Pregnancy-induced changes in cell-fate in the mammary gland.
Academic Article	Cooperative effects of STAT5 (signal transducer and activator of transcription 5) and C/EBPbeta (CCAAT/enhancer-binding protein-beta) on beta-casein gene transcription are mediated by the glucocorticoid receptor.
Academic Article	Glucocorticoid receptor/signal transducer and activator of transcription 5 (STAT5) interactions enhance STAT5 activation by prolonging STAT5 DNA binding and tyrosine phosphorylation.
Academic Article	Maintenance of milk protein gene expression in a subpopulation of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinoma cells grown on attached collagen gels.
Academic Article	Measurement of mRNA concentration and mRNA half-life as a function of hormonal treatment.
Academic Article	Regulation of casein messenger RNA during the development of the rat mammary gland. 1975.
Academic Article	The mammary gland as a bioreactor: factors regulating the efficient expression of milk protein-based transgenes.
Academic Article	The regulation of mammary gland development by hormones, growth factors, and oncogenes.
Academic Article	Casein gene expression: from transfection to transgenics.
Academic Article	Long term effects of perinatal injection of estrogen and progesterone on the morphological and biochemical development of the mammary gland.
Academic Article	Engineering transgenes for use in the mammary gland.
Academic Article	Minireview: hormones and mammary cell fate--what will I become when I grow up?
Academic Article	Mammary gland macrophages: pleiotropic functions in mammary development.
Academic Article	Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer.
Academic Article	The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes.
Academic Article	Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage.
Academic Article	PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland.
Academic Article	Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer.
Academic Article	Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation.
Academic Article	A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud.
Academic Article	Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers.
Academic Article	TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway.
Academic Article	Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression.
Academic Article	WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis.
Academic Article	Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.
Academic Article	FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.
Academic Article	miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution.
Grant	DEVELOPMENT OF A STOCHASTIC MOUSE TO STUDY BREAST CANCER
Academic Article	Metastasis Organotropism: Redefining the Congenial Soil.
Academic Article	The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor.
Academic Article	Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms.
Academic Article	C/EBP? Isoform Specific Gene Regulation: It's a Lot more Complicated than you Think!
Academic Article	Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer.
Academic Article	New twists on long noncoding RNAs: from mobile elements to motile cancer cells.
Academic Article	Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions.
Academic Article	TIME Is a Great Healer-Targeting Myeloid Cells in the Tumor Immune Microenvironment to Improve Triple-Negative Breast Cancer Outcomes.
Academic Article	Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer.
Academic Article	CD8+ T cells inhibit metastasis and CXCL4 regulates its function.
Academic Article	Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition.
Academic Article	Resistance to natural killer cell immunosurveillance confers a selective advantage to polyclonal metastasis.
Academic Article	Tumor suppressor PLK2 may serve as a biomarker in triple-negative breast cancer for improved response to PLK1 therapeutics.
Academic Article	Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer.
Academic Article	LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells.
Academic Article	STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential.
Academic Article	Targeted Inhibition of lncRNA Malat1 Alters the Tumor Immune Microenvironment in Preclinical Syngeneic Mouse Models of Triple-Negative Breast Cancer.
Academic Article	Targeting eIF4A triggers an interferon response to synergize with chemotherapy and suppress triple-negative breast cancer.

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