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SHULMAN, JOSHUA

One or more keywords matched the following items that are connected to SHULMAN, JOSHUA

Item Type	Name
Academic Article	PAR-1 is required for the maintenance of oocyte fate in Drosophila.
Academic Article	The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole.
Academic Article	Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways.
Academic Article	The role of PAR-1 in regulating the polarised microtubule cytoskeleton in the Drosophila follicular epithelium.
Academic Article	TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model.
Academic Article	S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila.
Academic Article	Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling.
Academic Article	From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease.
Academic Article	Genetic modifiers of tauopathy in Drosophila.
Academic Article	Functional screening of Alzheimer pathology genome-wide association signals in Drosophila.
Concept	Drosophila melanogaster
Concept	Drosophila Proteins
Concept	Drosophila
Academic Article	Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms.
Academic Article	Drosophila and experimental neurology in the post-genomic era.
Academic Article	Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease.
Academic Article	Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.
Academic Article	Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing.
Academic Article	Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits.
Academic Article	An ultra-fast and scalable quantification pipeline for transposable elements from next generation sequencing data.
Academic Article	Tau Activates Transposable Elements in Alzheimer's Disease.
Academic Article	A Druggable Genome Screen Identifies Modifiers of a-Synuclein Levels via a Tiered Cross-Species Validation Approach.
Grant	Functional Validation of the CD2AP Susceptibility Network in Alzheimer's Disease
Grant	Tau-Spliceosome Interactions in Alzheimer's Disease
Grant	Functional Dissection of Alzheimer's Disease Networks in Drosophila: from Association to Causal Modulators of Age-Dependent Neurodegeration
Grant	Functional Validation of Parkinsons Disease Susceptibility Genes in Drosophila
Grant	Exploring the Genetics of Alzheimer's Disease in Humans and Drosophila
Academic Article	cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis.
Academic Article	Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.
Academic Article	Genetic architecture of subcortical brain structures in 38,851 individuals.
Academic Article	Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain.
Grant	Metabolo-Genetic Dissection of GBA and Lysosomal Genes in Parkinson's Disease and Lewy Body Dementia
Academic Article	Integrated analysis of the aging brain transcriptome and proteome in tauopathy.
Grant	Bidirectional interactions between sleep and Alzheimer's disease: Functional dissection of the brain transcriptome in humans and Drosophila
Academic Article	TBK1 interacts with tau and enhances neurodegeneration in tauopathy.
Grant	Functional Genomic Dissection of Alzheimer's Disease in Humans and Drosophila Models
Academic Article	Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson's disease genes.
Academic Article	Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity.
Academic Article	Tau polarizes an aging transcriptional signature to excitatory neurons and glia.

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