| Item Type | Name |
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Academic Article
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Embryogenesis and oncogenesis: Dr Jekyll and Mr Hyde.
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Academic Article
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Next stop, the twilight zone: hedgehog network regulation of mammary gland development.
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Academic Article
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Accelerated mammary maturation and differentiation, and delayed MMTVneu-induced tumorigenesis of K303R mutant ERalpha transgenic mice.
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Academic Article
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Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling.
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Academic Article
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Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors.
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Academic Article
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Paracrine Wnt signaling both promotes and inhibits human breast tumor growth.
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Academic Article
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Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia.
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Academic Article
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Evidence that an early pregnancy causes a persistent decrease in the number of functional mammary epithelial stem cells--implications for pregnancy-induced protection against breast cancer.
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Academic Article
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Faith, heresy and the cancer stem cell hypothesis.
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Academic Article
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Scaffold Attachment Factor B1 (SAFB1) heterozygosity does not influence Wnt-1 or DMBA-induced tumorigenesis.
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Academic Article
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Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells.
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Academic Article
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Methods for preparing fluorescent and neutral red-stained whole mounts of mouse mammary glands.
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Academic Article
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The more things change... the more things change: developmental plasticity of tumor-initiating mammary epithelial cells.
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Academic Article
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Constitutive activation of smoothened leads to female infertility and altered uterine differentiation in the mouse.
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Academic Article
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Hedgehog signaling in the normal and neoplastic mammary gland.
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Academic Article
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High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy.
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Academic Article
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Estrogen promotes ER-negative tumor growth and angiogenesis through mobilization of bone marrow-derived monocytes.
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Academic Article
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Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model.
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Academic Article
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Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells.
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Academic Article
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P190A RhoGAP is required for mammary gland development.
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Academic Article
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ID4 regulates mammary gland development by suppressing p38MAPK activity.
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Academic Article
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A mystery wrapped in an enigma: Matrigel enhancement of mammary cell growth and morphogenesis.
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Academic Article
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Separation by cell size enriches for mammary stem cell repopulation activity.
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Academic Article
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Introduction of oncogenes into mammary glands in vivo with an avian retroviral vector initiates and promotes carcinogenesis in mouse models.
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Academic Article
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Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail.
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Academic Article
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Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation.
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Academic Article
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Mesenchymal stem cells promote mammosphere formation and decrease E-cadherin in normal and malignant breast cells.
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Academic Article
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Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened.
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Concept
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Mammary Glands, Animal
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Concept
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Pregnancy, Animal
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Concept
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Disease Models, Animal
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Concept
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Mammary Neoplasms, Animal
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Concept
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Animals
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Academic Article
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A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models.
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Academic Article
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The hedgehog signaling network, mammary stem cells, and breast cancer: connections and controversies.
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Academic Article
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Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.
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Academic Article
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A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis.
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Academic Article
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Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer.
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Academic Article
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STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer.
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Academic Article
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Striking sequence similarity among sialic acid-binding lectin, pancreatic ribonucleases, and angiogenin: possible structural and functional relationships.
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Academic Article
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Identification and Characterization of Separase Inhibitors (Sepins) for Cancer Therapy.
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Academic Article
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Methods in mammary gland biology and breast cancer research: an update.
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Academic Article
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The Gli2 transcription factor is required for normal mouse mammary gland development.
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Academic Article
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Hedgehog signaling in mouse mammary gland development and neoplasia.
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Academic Article
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Homeobox genes in mammary gland development and neoplasia.
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Academic Article
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Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1.
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Academic Article
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Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast.
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Academic Article
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Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis.
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Academic Article
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Patient-derived xenograft models of breast cancer and their predictive power.
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Academic Article
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Identifying and targeting tumor-initiating cells in the treatment of breast cancer.
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Academic Article
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Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation.
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Academic Article
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An essential role for Ga(i2) in Smoothened-stimulated epithelial cell proliferation in the mammary gland.
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Academic Article
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Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation.
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Academic Article
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Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer.
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Academic Article
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A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud.
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Academic Article
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Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.
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Academic Article
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Patient-derived xenograft (PDX) models in basic and translational breast cancer research.
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Academic Article
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The Terminal End Bud: the Little Engine that Could.
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Academic Article
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Epithelial and non-epithelial Ptch1 play opposing roles to regulate proliferation and morphogenesis of the mouse mammary gland.
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Academic Article
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Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming.
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Academic Article
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EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells.
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Academic Article
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New paradigms for the Hedgehog signaling network in mammary gland development and breast Cancer.
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Academic Article
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Carbon nanotube capsules enhance the in vivo efficacy of cisplatin.
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Academic Article
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TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer.
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Academic Article
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Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.
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Academic Article
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Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer.
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Academic Article
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PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.
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Academic Article
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Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer.
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Academic Article
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gpGrouper: A Peptide Grouping Algorithm for Gene-Centric Inference and Quantitation of Bottom-Up Proteomics Data.
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Academic Article
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Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes.
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Academic Article
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C/EBPd links IL-6 and HIF-1 signaling to promote breast cancer stem cell-associated phenotypes.
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Academic Article
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Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis.
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Academic Article
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Chromosome 12p Amplification in Triple-Negative/BRCA1-Mutated Breast Cancer Associates with Emergence of Docetaxel Resistance and Carboplatin Sensitivity.
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Academic Article
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S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation.
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Academic Article
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The Altered Transcriptome and DNA Methylation Profiles of Docetaxel Resistance in Breast Cancer PDX Models.
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Grant
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INTEGRATING OMICS AND QUANTITATIVE IMAGING DATA IN CO-CLINICAL TRIALS TO PREDICT TREATMENT RESPONSE IN TRIPLE NEGATIVE BREAST CANCER
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Academic Article
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Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer.
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Academic Article
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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
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Academic Article
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Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer.
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Academic Article
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MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma.
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Academic Article
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Co-Clinical Imaging Resource Program (CIRP): Bridging the Translational Divide to Advance Precision Medicine.
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Academic Article
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Hoxd10 Is Required Systemically for Secretory Activation in Lactation and Interacts Genetically with Hoxd9.
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Academic Article
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MEK activation modulates glycolysis and supports suppressive myeloid cells in TNBC.
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Academic Article
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Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment.
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Academic Article
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Transcriptional Reprogramming Differentiates Active from Inactive ESR1 Fusions in Endocrine Therapy-Refractory Metastatic Breast Cancer.
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Academic Article
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MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade.
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Academic Article
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Tumor suppressor PLK2 may serve as a biomarker in triple-negative breast cancer for improved response to PLK1 therapeutics.
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Academic Article
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Surgical Procedure for Implantation of Human Tumor Tissue into the Epithelium-Free Mammary Fat Pad of Immunocompromised Mice to Generate Patient-Derived Xenografts (PDX).
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Academic Article
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The Power and Promise of Patient-Derived Xenografts of Human Breast Cancer.
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