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KIRKWOOD, JOHN
One or more keywords matched the following items that are connected to KIRKWOOD, JOHN
Item TypeName
Concept Skin Ulcer
Concept Skin Neoplasms
Concept Skin
Academic Article Pan-erbB inhibition potentiates BRAF inhibitors for melanoma treatment.
Academic Article New TNM melanoma staging system: linking biology and natural history to clinical outcomes.
Academic Article Age as a predictor of sentinel node metastasis among patients with localized melanoma: an inverse correlation of melanoma mortality and incidence of sentinel node metastasis among young and old patients.
Academic Article Immunogenicity for CD8+ and CD4+ T cells of 2 formulations of an incomplete freund's adjuvant for multipeptide melanoma vaccines.
Academic Article Future perspectives in melanoma research. Meeting report from the "Melanoma research: a bridge from Naples to the World. Napoli, December 5th-6th 2011".
Academic Article An evidence-based staging system for cutaneous melanoma.
Academic Article Age as a prognostic factor in patients with localized melanoma and regional metastases.
Academic Article Final version of 2009 AJCC melanoma staging and classification.
Academic Article Innovations and challenges in melanoma: summary statement from the first Cambridge conference.
Academic Article Multivariate analysis of prognostic factors among 2,313 patients with stage III melanoma: comparison of nodal micrometastases versus macrometastases.
Academic Article Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis.
Academic Article Management of metastatic melanoma.
Academic Article Safety and efficacy of arsenic trioxide for patients with advanced metastatic melanoma.
Academic Article Safety and efficacy of combination immunotherapy with interferon alfa-2b and tremelimumab in patients with stage IV melanoma.
Academic Article High-dose interleukin-2 (HD IL-2) for advanced melanoma: a single center experience from the University of Pittsburgh Cancer Institute.
Academic Article Sentinel Lymph Node Biopsy and Management of Regional Lymph Nodes in Melanoma: American Society of Clinical Oncology and Society of Surgical Oncology Clinical Practice Guideline Update.
Academic Article Sentinel Lymph Node Biopsy and Management of Regional Lymph Nodes in Melanoma: American Society of Clinical Oncology and Society of Surgical Oncology Clinical Practice Guideline Update.
Academic Article Melanoma staging: Evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manual.
Academic Article Evaluation of Biodistribution of Sulforaphane after Administration of Oral Broccoli Sprout Extract in Melanoma Patients with Multiple Atypical Nevi.
Academic Article Multiple antigen-engineered DC vaccines with or without IFNa to promote antitumor immunity in melanoma.
Academic Article KEYNOTE-716: Phase III study of adjuvant pembrolizumab versus placebo in resected high-risk stage II melanoma.
Academic Article Results from a randomized phase III study comparing combined treatment with histamine dihydrochloride plus interleukin-2 versus interleukin-2 alone in patients with metastatic melanoma.
Academic Article An update on adjuvant interferon for melanoma.
Academic Article Quality-of-life-adjusted survival analysis of high-dose adjuvant interferon alpha-2b for high-risk melanoma patients using intergroup clinical trial data.
Academic Article Medical management of melanoma.
Academic Article Immunomodulatory effects of high-dose and low-dose interferon alpha2b in patients with high-risk resected melanoma: the E2690 laboratory corollary of intergroup adjuvant trial E1690.
Academic Article Sentinel lymph node biopsy and adjuvant therapy for melanoma: evidence revisited.
Academic Article Present status and future prospects for adjuvant therapy of melanoma: time to build upon the foundation of high-dose interferon alfa-2b.
Academic Article Adjuvant high-dose interferon-alpha therapy for high-risk melanoma.
Academic Article Mature results of a phase III randomized trial of bacillus Calmette-Guerin (BCG) versus observation and BCG plus dacarbazine versus BCG in the adjuvant therapy of American Joint Committee on Cancer Stage I-III melanoma (E1673): a trial of the Eastern Oncology Group.
Academic Article Temozolomide in combination with interferon alpha-2b in patients with metastatic melanoma: a phase I dose-escalation study.
Academic Article Fluorescence imaging analysis of upstream regulators and downstream targets of STAT3 in melanoma precursor lesions obtained from patients before and after systemic low-dose interferon-alpha treatment.
Academic Article Adjuvant therapy of melanoma.
Academic Article Melanoma vaccines: early progress and future promises.
Academic Article Melanoma in the older person.
Academic Article Temozolomide for the treatment of brain metastases associated with metastatic melanoma: a phase II study.
Academic Article Does childhood vaccination and exposure to infection improve long-term survival in patients with malignant melanoma?
Academic Article Melanoma.
Academic Article Strategies for the development of more effective adjuvant therapy of melanoma: current and future explorations of antibodies, cytokines, vaccines, and combinations.
Academic Article Accumulation of low-avidity anti-melanocortin receptor 1 (anti-MC1R) CD8+ T cells in the lesional skin of a patient with melanoma-related depigmentation.
Academic Article Prognostic significance of autoimmunity during treatment of melanoma with interferon.
Academic Article Radiosurgery for the treatment of spinal melanoma metastases.
Academic Article Multiplex analysis of serum cytokines in melanoma patients treated with interferon-alpha2b.
Academic Article Endostatin plus interferon-alpha2b therapy for metastatic melanoma: a novel combination of antiangiogenic and immunomodulatory agents.
Academic Article Durable complete responses with high-dose bolus interleukin-2 in patients with metastatic melanoma who have experienced progression after biochemotherapy.
Academic Article Neoadjuvant treatment of regional stage IIIB melanoma with high-dose interferon alfa-2b induces objective tumor regression in association with modulation of tumor infiltrating host cellular immune responses.
Academic Article Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group.
Academic Article Molecularly targeted therapy for melanoma: current reality and future options.
Academic Article Sentinel lymph node biopsy for atypical melanocytic lesions with spitzoid features.
Academic Article Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials.
Academic Article Practical guidelines for the management of interferon-alpha-2b side effects in patients receiving adjuvant treatment for melanoma: expert opinion.
Academic Article STAT3 as a biomarker of progression in atypical nevi of patients with melanoma: dose-response effects of systemic IFNalpha therapy.
Academic Article Modulation of signal transducers and activators of transcription 1 and 3 signaling in melanoma by high-dose IFNalpha2b.
Academic Article Oblimersen in the treatment of metastatic melanoma.
Academic Article Next generation of immunotherapy for melanoma.
Academic Article Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8+ T cells in melanoma patients.
Academic Article A phase 2, randomized study of SB-485232, rhIL-18, in patients with previously untreated metastatic melanoma.
Academic Article Gamma knife radiosurgery for malignant melanoma brain metastases.
Academic Article Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 Study Group.
Academic Article Biomarkers of therapeutic response in melanoma and renal cell carcinoma: potential inroads to improved immunotherapy.
Academic Article Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors.
Academic Article A phase 2 trial of sequential temozolomide chemotherapy followed by high-dose interleukin 2 immunotherapy for metastatic melanoma.
Academic Article Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma.
Academic Article A randomized phase 2 study of etaracizumab, a monoclonal antibody against integrin alpha(v)beta(3), + or - dacarbazine in patients with stage IV metastatic melanoma.
Academic Article A multi-center phase II evaluation of the small molecule survivin suppressor YM155 in patients with unresectable stage III or IV melanoma.
Academic Article Correlation of molecular human leukocyte antigen typing and outcome in high-risk melanoma patients receiving adjuvant interferon.
Academic Article Presence of tumor-infiltrating lymphocytes and a dominant nodule within primary melanoma are prognostic factors for relapse-free survival of patients with thick (t4) primary melanoma: pathologic analysis of the e1690 and e1694 intergroup trials.
Academic Article Melanoma in pediatric, adolescent, and young adult patients.
Academic Article Phase II trial of tremelimumab (CP-675,206) in patients with advanced refractory or relapsed melanoma.
Academic Article Systematic review of medical treatment in melanoma: current status and future prospects.
Academic Article Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-alpha 2b treatment.
Academic Article Meeting report from the Third Global Workshop on Melanoma.
Academic Article Methylation levels of the "long interspersed nucleotide element-1" repetitive sequences predict survival of melanoma patients.
Academic Article Aflibercept (VEGF Trap) in inoperable stage III or stage iv melanoma of cutaneous or uveal origin.
Academic Article A phase 2 study of tasisulam sodium (LY573636 sodium) as second-line treatment for patients with unresectable or metastatic melanoma.
Academic Article Neoadjuvant therapy for high-risk bulky regional melanoma.
Academic Article Melanoma: from research to treatment.
Academic Article The role of BRAF V600 mutation in melanoma.
Academic Article New therapies in the treatment of melanoma.
Academic Article Progression of cutaneous melanoma: implications for treatment.
Academic Article How much of a good thing? What duration for interferon alfa-2b adjuvant therapy?
Academic Article Adjuvant therapy: melanoma.
Academic Article Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma.
Academic Article Characterization of an early passage Merkel cell polyomavirus-positive Merkel cell carcinoma cell line, MS-1, and its growth in NOD scid gamma mice.
Academic Article The Society for Immunotherapy of Cancer consensus statement on tumour immunotherapy for the treatment of cutaneous melanoma.
Academic Article Advances in adjuvant therapy: potential for prognostic and predictive biomarkers.
Academic Article Pathologic and gene expression features of metastatic melanomas to the brain.
Academic Article Pediatric melanoma: analysis of an international registry.
Academic Article Adjuvant immunotherapy of melanoma and development of new approaches using the neoadjuvant approach.
Academic Article Atypical Spitzoid neoplasms: a review of potential markers of biological behavior including sentinel node biopsy.
Academic Article A four-marker signature of TNF-RII, TGF-a, TIMP-1 and CRP is prognostic of worse survival in high-risk surgically resected melanoma.
Academic Article ECOG phase II trial of graded-dose peginterferon a-2b in patients with metastatic melanoma overexpressing basic fibroblast growth factor (E2602).
Academic Article State of melanoma: an historic overview of a field in transition.
Academic Article Serologic evidence of autoimmunity in E2696 and E1694 patients with high-risk melanoma treated with adjuvant interferon alfa.
Academic Article Correlation of somatic mutations and clinical outcome in melanoma patients treated with Carboplatin, Paclitaxel, and sorafenib.
Academic Article Addressing the knowledge gap in clinical recommendations for management and complete excision of clinically atypical nevi/dysplastic nevi: Pigmented Lesion Subcommittee consensus statement.
Academic Article Unfolding the mutational landscape of human melanoma.
Academic Article Ipilimumab plus sargramostim vs ipilimumab alone for treatment of metastatic melanoma: a randomized clinical trial.
Academic Article IL10 and PD-1 Cooperate to Limit the Activity of Tumor-Specific CD8+ T Cells.
Academic Article Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial.
Academic Article Randomized, Placebo-Controlled, Phase III Trial of Yeast-Derived Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Versus Peptide Vaccination Versus GM-CSF Plus Peptide Vaccination Versus Placebo in Patients With No Evidence of Disease After Complete Surgical Resection of Locally Advanced and/or Stage IV Melanoma: A Trial of the Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer Research Group (E4697).
Academic Article Tumor associated PD-L1 expression pattern in microscopically tumor positive sentinel lymph nodes in patients with melanoma.
Academic Article BRAF Inhibitors and IFNa: Plus, Minus, or Indeterminate?
Academic Article Telomerase Expression by Aberrant Methylation of the TERT Promoter in Melanoma Arising in Giant Congenital Nevi.
Academic Article Phase III Randomized Study of 4 Weeks of High-Dose Interferon-a-2b in Stage T2bNO, T3a-bNO, T4a-bNO, and T1-4N1a-2a (microscopic) Melanoma: A Trial of the Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer Research Group (E1697).
Academic Article Downstream consequences of melanoma screening in a community practice setting: First results.
Academic Article A phase 2 trial of dasatinib in patients with locally advanced or stage IV mucosal, acral, or vulvovaginal melanoma: A trial of the ECOG-ACRIN Cancer Research Group (E2607).
Academic Article Safety and efficacy of the antiganglioside GD3 antibody ecromeximab (KW2871) combined with high-dose interferon-a2b in patients with metastatic melanoma.
Academic Article Whole-blood RNA transcript-based models can predict clinical response in two large independent clinical studies of patients with advanced melanoma treated with the checkpoint inhibitor, tremelimumab.
Academic Article High frequency of brain metastases after adjuvant therapy for high-risk melanoma.
Academic Article Prospective Validation of Molecular Prognostic Markers in Cutaneous Melanoma: A Correlative Analysis of E1690.
Academic Article Relapse-Free Survival as a Surrogate for Overall Survival in the Evaluation of Stage II-III Melanoma Adjuvant Therapy.
Academic Article A Large Skin Cancer Screening Quality Initiative: Description and First-Year Outcomes.
Academic Article Adjuvant interferon-a for the treatment of high-risk melanoma: An individual patient data meta-analysis.
Academic Article Skin cancer screening: recommendations for data-driven screening guidelines and a review of the US Preventive Services Task Force controversy.
Academic Article A unique gene expression signature is significantly differentially expressed in tumor-positive or tumor-negative sentinel lymph nodes in patients with melanoma.
Academic Article Three antigen-loading methods in dendritic cell vaccines for metastatic melanoma.
Academic Article Estimating the cost of skin cancer detection by dermatology providers in a large health care system.
Academic Article Management strategies of academic pigmented lesion clinic directors in the United States.
Academic Article Adjuvant Therapy in Resected Melanoma.
Academic Article Pooled Analysis Safety Profile of Nivolumab and Ipilimumab Combination Therapy in Patients With Advanced Melanoma.
Academic Article Nivolumab Plus Ipilimumab in Patients With Advanced Melanoma: Updated Survival, Response, and Safety Data in a Phase I Dose-Escalation Study.
Academic Article Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma.
Academic Article An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunotherapy for the treatment of cutaneous melanoma: version 2.0.
Academic Article MAGE-A3 immunotherapeutic as adjuvant therapy for patients with resected, MAGE-A3-positive, stage III melanoma (DERMA): a double-blind, randomised, placebo-controlled, phase 3 trial.
Academic Article Patient-reported outcomes in patients with resected, high-risk melanoma with BRAFV600E or BRAFV600K mutations treated with adjuvant dabrafenib plus trametinib (COMBI-AD): a randomised, placebo-controlled, phase 3 trial.
Academic Article Longer Follow-Up Confirms Relapse-Free Survival Benefit With Adjuvant Dabrafenib Plus Trametinib in Patients With Resected BRAF V600-Mutant Stage III Melanoma.
Academic Article Neoadjuvant ipilimumab (3?mg/kg or 10?mg/kg) and high dose IFN-a2b in locally/regionally advanced melanoma: safety, efficacy and impact on T-cell repertoire.
Academic Article Thick melanoma is associated with low melanoma knowledge and low perceived health competence, but not delays in care.
Academic Article Adjuvant dabrafenib plus trametinib versus placebo in patients with resected, BRAFV600-mutant, stage III melanoma (COMBI-AD): exploratory biomarker analyses from a randomised, phase 3 trial.
Academic Article Reactivation of tuberculosis in cancer patients following administration of immune checkpoint inhibitors: current evidence and clinical practice recommendations.
Academic Article Phase III Study of Adjuvant Ipilimumab (3 or 10 mg/kg) Versus High-Dose Interferon Alfa-2b for Resected High-Risk Melanoma: North American Intergroup E1609.
Academic Article Developing agents for the therapeutic prevention of melanoma: can the assessment of cutaneous precursor lesions help?
Academic Article Systemic Therapy for Melanoma: ASCO Guideline.
Academic Article Clinical Development of BRAF plus MEK Inhibitor Combinations.
Academic Article Prognostic Gene Expression Profiling in Cutaneous Melanoma: Identifying the Knowledge Gaps and Assessing the Clinical Benefit.
Academic Article Five-Year Analysis of Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma.
Academic Article Molecular and immunological associations of elevated serum lactate dehydrogenase in metastatic melanoma patients: A fresh look at an old biomarker.
Academic Article Indoor tanning exposure in association with multiple primary melanoma.
Academic Article The State of Melanoma: Emergent Challenges and Opportunities.
Academic Article CTLA-4 blockade and interferon-a induce proinflammatory transcriptional changes in the tumor immune landscape that correlate with pathologic response in melanoma.
Academic Article Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients.
Academic Article Neoadjuvant Pembrolizumab and High-Dose IFNa-2b in Resectable Regionally Advanced Melanoma.
Academic Article State of Melanoma: An Historic Overview of a Field in Transition.
Academic Article Immune adverse events (irAEs) with adjuvant ipilimumab in melanoma, use of immunosuppressants and association with outcome: ECOG-ACRIN E1609 study analysis.
Academic Article Prognosis and Management of BRAF V600E-Mutated Pregnancy-Associated Melanoma.
Academic Article Predictors of response to interferon therapy.
Academic Article Dysregulated NF-?B-Dependent ICOSL Expression in Human Dendritic Cell Vaccines Impairs T-cell Responses in Patients with Melanoma.
Academic Article Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding.
Academic Article Improved prognosis and evidence of enhanced immunogenicity in tumor and circulation of high-risk melanoma patients with unknown primary.
Academic Article Poorer survival outcomes in patients with multiple versus single primary melanoma.
Academic Article Neratinib kills B-RAF V600E melanoma via ROS-dependent autophagosome formation and death receptor signaling.
Academic Article Five-Year Outcomes of a Melanoma Screening Initiative in a Large Health Care System.
Academic Article A retrospective analysis of the impact of the COVID-19 pandemic on staging at presentation of patients with invasive melanoma.
Academic Article Clinically Significant Risk Thresholds in the Management of Primary Cutaneous Melanoma: A Survey of Melanoma Experts.
Academic Article Enhanced immune activation within the tumor microenvironment and circulation of female high-risk melanoma patients and improved survival with adjuvant CTLA4 blockade compared to males.
Academic Article Prognosis of Patients With Primary Melanoma Stage I and II According to American Joint Committee on Cancer Version 8 Validated in Two Independent Cohorts: Implications for Adjuvant Treatment.
Academic Article Combination Dabrafenib and Trametinib Versus Combination Nivolumab and Ipilimumab for Patients With Advanced BRAF-Mutant Melanoma: The DREAMseq Trial-ECOG-ACRIN EA6134.
Academic Article Clinical Features Associated with Outcomes and Biomarker Analysis of Dabrafenib plus Trametinib Treatment in Patients with BRAF-Mutant Melanoma Brain Metastases.
Academic Article Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma (KEYNOTE-716): distant metastasis-free survival results of a multicentre, double-blind, randomised, phase 3 trial.
Academic Article TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma.
Academic Article Multiple primary melanoma in association with other personal and familial cancers.
Academic Article Efficacy and safety of lifileucel, a one-time autologous tumor-infiltrating lymphocyte (TIL) cell therapy, in patients with advanced melanoma after progression on immune checkpoint inhibitors and targeted therapies: pooled analysis of consecutive cohorts of the C-144-01 study.
Academic Article Neoadjuvant-Adjuvant or Adjuvant-Only Pembrolizumab in Advanced Melanoma.
Academic Article Early Detection and Prognostic Assessment of Cutaneous Melanoma: Consensus on Optimal Practice and the Role of Gene Expression Profile Testing.
Academic Article Tebentafusp in combination with durvalumab and/or tremelimumab in patients with metastatic cutaneous melanoma: a phase 1 study.
Academic Article Systemic Therapy for Melanoma: ASCO Guideline Update.
Academic Article Adjuvant nivolumab in resected stage IIB/C melanoma: primary results from the randomized, phase 3 CheckMate 76K trial.
Academic Article Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma.
Academic Article Prognostic gene expression profile testing to inform use of adjuvant therapy: A survey of melanoma experts.
Academic Article Plain language summary of the CheckMate 76K study results: nivolumab given after stage 2B/2C?melanoma is removed by surgery.
Academic Article Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma: Outcomes in histopathologic subgroups from the randomized, double-blind, phase 3 KEYNOTE-716 trial.
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