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GRIMM, ELIZABETH A

One or more keywords matched the following items that are connected to GRIMM, ELIZABETH A

Item Type	Name
Academic Article	A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells.
Academic Article	Promotion of melanoma growth by the metabolic hormone leptin.
Academic Article	Targeted inhibition of inducible nitric oxide synthase inhibits growth of human melanoma in vivo and synergizes with chemotherapy.
Academic Article	Differential increase of Fas ligand expression on metastatic and thin or thick primary melanoma cells compared with interleukin-10.
Academic Article	Expression of thyrotropin-releasing hormone by human melanoma and nevi.
Academic Article	Changes in pERK1/2 and pAKT expression in melanoma lesions after imatinib treatment.
Academic Article	A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells.
Academic Article	The expression of p-STAT3 in stage IV melanoma: risk of CNS metastasis and survival.
Concept	Melanoma
Concept	Melanoma, Experimental
Academic Article	Molecular pathways: inflammation-associated nitric-oxide production as a cancer-supporting redox mechanism and a potential therapeutic target.
Academic Article	Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2.
Academic Article	Lysis of fresh human solid tumors by autologous lymphocytes activated in vitro with lectins.
Academic Article	Tumor target binding induces phosphorylation of two M(r) 65,000 lymphokine-activated killer proteins.
Academic Article	Interaction of chemotherapy and biological response modifiers in the treatment of melanoma.
Academic Article	DNA damage in peripheral blood mononuclear cells correlates with response to biochemotherapy in melanoma.
Academic Article	Significance of plasma cytokine levels in melanoma patients with histologically negative sentinel lymph nodes.
Academic Article	Inhibition of nuclear factor-kappaB and nitric oxide by curcumin induces G2/M cell cycle arrest and apoptosis in human melanoma cells.
Academic Article	Regulation of iNOS by the p44/42 mitogen-activated protein kinase pathway in human melanoma.
Academic Article	Soluble human MDA-7/IL-24: characterization of the molecular form(s) inhibiting tumor growth and stimulating monocytes.
Academic Article	Interleukin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells.
Academic Article	Clinical correlates of NRAS and BRAF mutations in primary human melanoma.
Academic Article	Genome-wide association study identifies novel loci predisposing to cutaneous melanoma.
Academic Article	Constitutive aberrant endogenous interleukin-1 facilitates inflammation and growth in human melanoma.
Academic Article	Variants in melanocortin 1 receptor gene contribute to risk of melanoma--a direct sequencing analysis in a Texas population.
Academic Article	A rapid assay for stimulation of human lymphocytes by tumor-associated antigens.
Academic Article	Tumor recognition and lytic competence of IL-2-activated lymphocytes: regulation of both antibody-independent and -dependent cellular cytotoxicity via P75 IL-2 receptor.
Academic Article	Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.
Academic Article	Suppressive immunoregulatory factors produced by tumors.
Academic Article	Immunoregulatory factors derived from human tumors. I. Immunologic and biochemical characterization of factors that suppress lymphocyte proliferative and cytotoxic responses in vitro.
Academic Article	Lysis of human solid tumors by autologous cells sensitized in vitro to alloantigens.
Academic Article	Interleukin-6 production and secretion in human melanoma cell lines: regulation by interleukin-1.
Academic Article	Down-regulated melanoma differentiation associated gene (mda-7) expression in human melanomas.
Academic Article	Melanoma differentiation-associated gene 7/interleukin (IL)-24 is a novel ligand that regulates angiogenesis via the IL-22 receptor.
Academic Article	Tumor iNOS predicts poor survival for stage III melanoma patients.
Academic Article	Genetic variants of the vitamin D receptor gene alter risk of cutaneous melanoma.
Academic Article	WP760, a melanoma selective drug.
Academic Article	Genetic variants and haplotypes of the caspase-8 and caspase-10 genes contribute to susceptibility to cutaneous melanoma.
Academic Article	Zyflamend mediates therapeutic induction of autophagy to apoptosis in melanoma cells.
Academic Article	Identification of unique sensitizing targets for anti-inflammatory CDDO-Me in metastatic melanoma by a large-scale synthetic lethal RNAi screening.
Academic Article	Detection of tumor-associated antigen in human melanoma cell line supernatants.
Academic Article	Cytokine responses to intraventricular injection of interleukin 2 into patients with leptomeningeal carcinomatosis: rapid induction of tumor necrosis factor alpha, interleukin 1 beta, interleukin 6, gamma-interferon, and soluble interleukin 2 receptor (Mr 55,000 protein).
Academic Article	Phenotype and cytolytic activity of mouse tumor-bearer splenocytes and tumor-infiltrating lymphocytes from K-1735 melanoma metastases following anti-CD3, interleukin-2, and tumor necrosis factor-alpha combination immunotherapy.
Academic Article	Interleukin-1 production in tumor cells of human melanoma surgical specimens.
Academic Article	Characterization of the M(r) 65,000 lymphokine-activated killer proteins phosphorylated after tumor target binding: evidence that pp65a and pp65b are phosphorylated forms of L-plastin.
Academic Article	Evaluation of tyrosinase mRNA as a tumor marker in the blood of melanoma patients.
Academic Article	Nitric oxide and neopterin levels and clinical response in stage III melanoma patients receiving concurrent biochemotherapy.
Academic Article	Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival.
Academic Article	A novel preclinical model of human malignant melanoma utilizing bioreactor rotating-wall vessels.
Academic Article	Autoimmunity and hypothyroidism in patients with uveal melanoma.
Academic Article	Negative association of melanoma differentiation-associated gene (mda-7) and inducible nitric oxide synthase (iNOS) in human melanoma: MDA-7 regulates iNOS expression in melanoma cells.
Academic Article	mda-7/IL-24, a novel cancer selective apoptosis inducing cytokine gene: from the laboratory into the clinic.
Academic Article	Depletion of endogenous nitric oxide enhances cisplatin-induced apoptosis in a p53-dependent manner in melanoma cell lines.
Academic Article	Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism.
Academic Article	Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients.
Academic Article	Genetic variants of the ADPRT, XRCC1 and APE1 genes and risk of cutaneous melanoma.
Academic Article	Polymorphisms in the DNA repair genes XPC, XPD, and XPG and risk of cutaneous melanoma: a case-control analysis.
Academic Article	Polymorphisms of the neuronal and inducible nitric oxide synthase genes and the risk of cutaneous melanoma: a case-control study.
Academic Article	Polymorphisms of TP53 Arg72Pro, but not p73 G4C14>A4TA4 and p21 Ser31Arg, contribute to risk of cutaneous melanoma.
Academic Article	Constitutive intracellular production of iNOS and NO in human melanoma: possible role in regulation of growth and resistance to apoptosis.
Academic Article	Killing of human melanoma cells induced by activation of class I interferon-regulated signaling pathways via MDA-7/IL-24.
Academic Article	IL-24 gene transfer sensitizes melanoma cells to erlotinib through modulation of the Apaf-1 and Akt signaling pathways.
Academic Article	The role of melanoma tumor-derived nitric oxide in the tumor inflammatory microenvironment: its impact on the chemokine expression profile, including suppression of CXCL10.
Academic Article	Association of activated c-Met with NRAS-mutated human melanomas.
Academic Article	IL-2 regulates the expression of the tumor suppressor IL-24 in melanoma cells.
Academic Article	Influence of single nucleotide polymorphisms in the MMP1 promoter region on cutaneous melanoma progression.
Academic Article	Slug expression during melanoma progression.
Academic Article	Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma.
Academic Article	Polymorphisms of nucleotide excision repair genes predict melanoma survival.
Academic Article	Simultaneous inhibition of the HGF/MET and Erk1/2 pathways affect uveal melanoma cell growth and migration.
Academic Article	Successful combination immunotherapy for the generation in vivo of antitumor activity with anti-CD3, interleukin 2, and tumor necrosis factor alpha.
Academic Article	Mechanism of the anti-tumour effect of biochemotherapy in melanoma: preliminary results.
Academic Article	Unexpected cytokines in serum of malignant melanoma patients during sequential biochemotherapy.
Academic Article	Pilot study of high-dose, concurrent biochemotherapy for advanced melanoma.
Academic Article	Polymorphisms of the FAS and FAS ligand genes associated with risk of cutaneous malignant melanoma.
Academic Article	Haplotype and genotypes of the VDR gene and cutaneous melanoma risk in non-Hispanic whites in Texas: a case-control study.
Academic Article	NF-kappaB mediates mitogen-activated protein kinase pathway-dependent iNOS expression in human melanoma.
Academic Article	Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma.
Academic Article	Effect of surgery on in vitro lymphocyte function.
Academic Article	Presence of the human leukocyte antigen class II gene DRB1*1101 predicts interferon gamma levels and disease recurrence in melanoma patients.
Academic Article	High prevalence of hypothyroidism among patients with cutaneous melanoma.
Academic Article	Frequencies of NRAS and BRAF mutations increase from the radial to the vertical growth phase in cutaneous melanoma.
Academic Article	Expression of leptin and iNOS in oral melanomas in dogs.
Academic Article	Detection of melanoma cells in peripheral blood using reverse transcription polymerase chain reaction assay for tyrosinase mRNA.
Academic Article	Genetic analysis of the 'uveal melanoma' C918 cell line reveals atypical BRAF and common KRAS mutations and single tandem repeat profile identical to the cutaneous melanoma C8161 cell line.
Academic Article	Inflammatory IL-1?-driven JNK activation in stage III melanoma.
Academic Article	Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-?.
Academic Article	Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-?.
Academic Article	Dual Roles of RNF2 in Melanoma Progression.
Academic Article	Inflammatory marker testing identifies CD74 expression in melanoma tumor cells, and its expression associates with favorable survival for stage III melanoma
Academic Article	Dual roles of RNF2 in melanoma progression
Academic Article	4-nitroquinoline-1-oxide-induced mutagen sensitivity and risk of cutaneous melanoma
Academic Article	Braf mutations are associated with high levels of phosphorylated RKIP in melanoma cell lines
Academic Article	Immunology comes full circle in melanoma while specific immunity is unleashed to eliminate metastatic disease, inflammatory products of innate immunity promote resistance
Academic Article	Genetic analysis of the 'uveal melanoma' C918 cell line reveals atypical BRAF and common KRAS mutations and single tandem repeat profile identical to the cutaneous melanoma C8161 cell line
Academic Article	Elevated serum leptin levels are associated with an increased risk of sentinel lymph node metastasis in cutaneous melanoma
Academic Article	Biochemotherapy in the treatment of advanced melanoma
Academic Article	Microsomal PGE2 synthase-1 regulates melanoma cell survival and associates with melanoma disease progression
Academic Article	Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-Î³ (Journal of Investigative Dermatology (2015) 135 (2901) DOI
Academic Article	Uveal melanoma
Academic Article	Hypoxia-driven mechanism of vemurafenib resistance in melanoma
Academic Article	4-nitroquinoline-1-oxide-induced mutagen sensitivity and risk of cutaneous melanoma: a case-control analysis.
Academic Article	Microsomal PGE2 synthase-1 regulates melanoma cell survival and associates with melanoma disease progression.
Academic Article	Inflammatory Marker Testing Identifies CD74 Expression in Melanoma Tumor Cells, and Its Expression Associates with Favorable Survival for Stage III Melanoma.
Academic Article	Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma.
Academic Article	Immunology Comes Full Circle in Melanoma While Specific Immunity Is Unleashed to Eliminate Metastatic Disease, Inflammatory Products of Innate Immunity Promote Resistance.
Academic Article	Elevated Serum Leptin Levels are Associated With an Increased Risk of Sentinel Lymph Node Metastasis in Cutaneous Melanoma.
Academic Article	Uveal melanoma: From diagnosis to treatment and the science in between.
Academic Article	IL2 Variant Circumvents ICOS+ Regulatory T-cell Expansion and Promotes NK Cell Activation.
Academic Article	Trends in hepatocyte growth factor, insulin-like growth factor 1, thyroid-stimulating hormone, and leptin expression levels in uveal melanoma patient serum and tumor tissues: correlation to disease progression.
Academic Article	Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma.
Academic Article	Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.
Academic Article	Mitochondrial dynamic alterations regulate melanoma cell progression.
Academic Article	Targeting the HGF/MET Axis Counters Primary Resistance to KIT Inhibition in KIT-Mutant Melanoma.
Academic Article	The COX2 Effector Microsomal PGE2 Synthase 1 is a Regulator of Immunosuppression in Cutaneous Melanoma.
Academic Article	Tyrosine Kinase Inhibitor and Immune Checkpoint Inhibitor Responses in KIT-Mutant Metastatic Melanoma.
Concept	Melanoma-Specific Antigens
Academic Article	TNFSF4 (OX40L) expression and survival in locally advanced and metastatic melanoma.
Academic Article	Elevated Endogenous SDHA Drives Pathological Metabolism in Highly Metastatic Uveal Melanoma.
Academic Article	The Expression of CD74-Regulated Inflammatory Markers in Stage IV Melanoma: Risk of CNS Metastasis and Patient Survival.
Academic Article	iNOS Associates With Poor Survival in Melanoma: A Role for Nitric Oxide in the PI3K-AKT Pathway Stimulation and PTEN S-Nitrosylation.
Academic Article	Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma.
Academic Article	Correction: Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma.
Academic Article	Targeting IRS-1/2 in Uveal Melanoma Inhibits In Vitro Cell Growth, Survival and Migration, and In Vivo Tumor Growth.
Academic Article	Inhibition of Microsomal Prostaglandin E2 Synthase Reduces Collagen Deposition in Melanoma Tumors and May Improve Immunotherapy Efficacy by Reducing T-cell Exhaustion.
Academic Article	Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma.

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Melanoma