Item Type | Name |
Concept
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Kidney Glomerulus
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Concept
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Kidney Transplantation
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Concept
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Kidney Tubules, Proximal
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Concept
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Kidney Failure, Chronic
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Concept
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Kidney
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Concept
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Kidney Diseases
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Concept
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Kidney Cortex
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Concept
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Kidney Neoplasms
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Concept
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Kidney Tubules
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Concept
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Kidney Tubular Necrosis, Acute
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Academic Article
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Determinants of vascular permeability in the kidney glomerulus.
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Academic Article
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A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development.
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Academic Article
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Differential expression of type IV collagen isoforms in rat glomerular endothelial and mesangial cells.
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Academic Article
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Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes.
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Academic Article
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Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria.
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Academic Article
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The importance of cell-mediated immunity in the course and severity of autoimmune anti-glomerular basement membrane disease in mice.
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Academic Article
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Mice deficient in alpha-actinin-4 have severe glomerular disease.
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Academic Article
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BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury.
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Academic Article
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Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models.
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Academic Article
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Regulation by CD25+ lymphocytes of autoantigen-specific T-cell responses in Goodpasture's (anti-GBM) disease.
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Academic Article
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Epithelial-mesenchymal transition and its implications for fibrosis.
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Academic Article
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The role of epithelial-to-mesenchymal transition in renal fibrosis.
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Academic Article
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Induction of B7-1 in podocytes is associated with nephrotic syndrome.
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Academic Article
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Allograft rejection and glomerular basement membrane antibodies in Alport's syndrome.
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Academic Article
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Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney.
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Academic Article
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Bifunctional promoter of type IV collagen COL4A5 and COL4A6 genes regulates the expression of alpha5 and alpha6 chains in a distinct cell-specific fashion.
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Academic Article
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An unusual case of pulmonary-renal syndrome associated with defects in type IV collagen composition and anti-glomerular basement membrane autoantibodies.
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Academic Article
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TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function.
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Academic Article
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Recapitulation of kidney development paradigms by BMP-7 reverses chronic renal injury.
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Academic Article
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Cellular and molecular pathways that lead to progression and regression of renal fibrogenesis.
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Academic Article
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Animal models of renal fibrosis.
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Academic Article
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Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease.
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Academic Article
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Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease.
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Academic Article
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Proteinuria with and without renal glomerular podocyte effacement.
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Academic Article
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Alpha-actinin-4 is required for normal podocyte adhesion.
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Academic Article
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Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse.
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Academic Article
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Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia.
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Academic Article
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Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors.
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Academic Article
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Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus.
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Academic Article
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Modification of kidney barrier function by the urokinase receptor.
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Academic Article
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Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease.
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Academic Article
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Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis.
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Academic Article
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Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity.
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Academic Article
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Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition.
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Academic Article
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Circulating TGF-beta1 as a reliable biomarker for chronic kidney disease progression in the African-American population.
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Academic Article
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Renal studies provide an insight into cardiac extracellular matrix remodeling during health and disease.
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Academic Article
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The biology of preeclampsia.
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Academic Article
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Methylation determines fibroblast activation and fibrogenesis in the kidney.
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Academic Article
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Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly.
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Academic Article
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Mechanistic connection between inflammation and fibrosis.
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Academic Article
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Blockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis.
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Academic Article
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Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis.
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Academic Article
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TGF-?1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis.
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Academic Article
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Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis.
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Academic Article
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Origin and function of myofibroblasts in kidney fibrosis.
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Academic Article
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Reply to Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3.
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Academic Article
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Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis.
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Academic Article
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Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease.
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Academic Article
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Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure.
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Academic Article
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Are there endogenous molecules that protect kidneys from injury? The case for bone morphogenic protein-7 (BMP-7).
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Academic Article
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Circulating endoglin concentration is not elevated in chronic kidney disease.
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Academic Article
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The Kielin/chordin-like protein checkpoint constitutes a system of checks and balances in CKD.
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Academic Article
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Pathology of glomerular basement membrane nephropathy.
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Academic Article
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Goodpasture syndrome involving overlap with Wegener's granulomatosis and anti-glomerular basement membrane disease.
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Academic Article
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Experimental Goodpasture's syndrome in Wistar-Kyoto rats immunized with alpha3 chain of type IV collagen.
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Academic Article
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Goodpasture syndrome.
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Academic Article
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Angiotensin II induces alpha3(IV) collagen expression in cultured murine proximal tubular cells.
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Academic Article
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Osteopontin expressed by renal tubular epithelium mediates interstitial monocyte infiltration in rats.
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Academic Article
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Inhibition of monocyte chemoattractant protein-1 expression in tubular epithelium attenuates tubulointerstitial alteration in rat Goodpasture syndrome.
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Academic Article
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Blocking angiotensin II synthesis/activity preserves glomerular nephrin in rats with severe nephrosis.
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Academic Article
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Renal fibroblast-like cells in Goodpasture syndrome rats.
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Academic Article
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The pathogenesis of Alport syndrome involves type IV collagen molecules containing the alpha 3(IV) chain: evidence from anti-GBM nephritis after renal transplantation.
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Academic Article
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A COL4A3 gene mutation and post-transplant anti-alpha 3(IV) collagen alloantibodies in Alport syndrome.
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Academic Article
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Structure and organization of type IV collagen of renal glomerular basement membrane.
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Academic Article
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The alpha 3 chain of type IV collagen induces autoimmune Goodpasture syndrome.
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Academic Article
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Coordinate gene expression of the alpha3, alpha4, and alpha5 chains of collagen type IV. Evidence from a canine model of X-linked nephritis with a COL4A5 gene mutation.
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Academic Article
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Autoreactive T-cells in Goodpasture's syndrome recognize the N-terminal NC1 domain on alpha 3 type IV collagen.
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Academic Article
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Structural features of nephritogenic lupus autoantibodies.
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Academic Article
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Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis.
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Academic Article
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Human Goodpasture anti-alpha3(IV)NC1 autoantibodies share structural determinants.
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Academic Article
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Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy.
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Academic Article
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Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis.
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Academic Article
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Alveolar basement membrane: molecular properties of the noncollagenous domain (hexamer) of collagen IV and its reactivity with Goodpasture autoantibodies.
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Academic Article
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Comparative distribution of the alpha 1(IV), alpha 5(IV), and alpha 6(IV) collagen chains in normal human adult and fetal tissues and in kidneys from X-linked Alport syndrome patients.
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Academic Article
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Molecular characteristics of the Goodpasture autoantigen.
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Academic Article
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Identification of the alpha 3 chain of type IV collagen as the common autoantigen in antibasement membrane disease and Goodpasture syndrome.
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Academic Article
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Specificity of circulating and tissue-bound autoantibodies in Goodpasture syndrome.
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Academic Article
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Goodpasture syndrome: selective removal of anti-alpha 3 (IV) collagen autoantibodies. A potential therapeutic alternative to plasmapheresis.
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Academic Article
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Expression of type IV collagen alpha1(IV)-alpha6(IV) polypeptides in normal and developing human kidney and in renal cell carcinomas and oncocytomas.
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Academic Article
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Differential expression of collagen IV isoforms in experimental glomerulosclerosis.
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Academic Article
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Augmented expression of glomerular basement membrane specific type IV collagen isoforms (alpha3-alpha5) in experimental membranous nephropathy.
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Academic Article
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Role for transforming growth factor-beta1 in alport renal disease progression.
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Academic Article
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Identification of alpha3, alpha4, and alpha5 chains of type IV collagen as alloantigens for Alport posttransplant anti-glomerular basement membrane antibodies.
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Academic Article
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Reactive oxygen species expose cryptic epitopes associated with autoimmune goodpasture syndrome.
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Academic Article
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Distinct antitumor properties of a type IV collagen domain derived from basement membrane.
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Academic Article
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Assembly of type IV collagen. Insights from alpha3(IV) collagen-deficient mice.
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Academic Article
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Aminopeptidase A: a nephritogenic target antigen of nephrotoxic serum.
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Academic Article
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Cell surface glypicans are low-affinity endostatin receptors.
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Academic Article
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Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation.
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Academic Article
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Human antiglomerular basement membrane autoantibody disease in XenoMouse II.
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Academic Article
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NPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-associated allele.
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Academic Article
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Exploring the connection between chronic renal fibrosis and bone morphogenic protein-7.
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Academic Article
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Targeted downregulation of extracellular nephrin in human IgA nephropathy.
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Academic Article
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Selective impairment of gene expression and assembly of nephrin in human diabetic nephropathy.
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Academic Article
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Glomerular basement membrane. Identification of dimeric subunits of the noncollagenous domain (hexamer) of collagen IV and the Goodpasture antigen.
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Academic Article
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COL4A5 gene deletion and production of post-transplant anti-alpha 3(IV) collagen alloantibodies in Alport syndrome.
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Academic Article
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Early and advanced non-enzymatic glycation products in the pathogenesis of diabetic kidney disease.
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Academic Article
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Susceptibility to anti-glomerular basement membrane disease and Goodpasture syndrome is linked to MHC class II genes and the emergence of T cell-mediated immunity in mice.
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Academic Article
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High affinity of anti-GBM antibodies from Goodpasture and transplanted Alport patients to alpha3(IV)NC1 collagen.
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Academic Article
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Contribution of epithelial plasticity to renal transplantation-associated fibrosis.
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Academic Article
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A monoclonal antibody marker for Alport syndrome identifies the Alport antigen as the alpha 5 chain of type IV collagen.
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Academic Article
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Early role of Fsp1 in epithelial-mesenchymal transformation.
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Academic Article
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Differential expression of collagen type IV alpha-chains in the tubulointerstitial compartment in experimental chronic serum sickness nephritis.
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Academic Article
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Intrathymic kidney cells delay the onset of lupus nephritis in MRL-lpr/lpr mice.
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Academic Article
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Physiology of the Renal Interstitium.
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Academic Article
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Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis.
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Academic Article
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Partial Epithelial-to-Mesenchymal Transition and Other New Mechanisms of Kidney Fibrosis
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Academic Article
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Possible mechanisms of kidney repair
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Academic Article
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Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure
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Academic Article
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Kidney International
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Academic Article
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Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease
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Academic Article
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Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease.
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Academic Article
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Partial Epithelial-to-Mesenchymal Transition and Other New Mechanisms of Kidney Fibrosis.
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Academic Article
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Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury-to-chronic kidney disease progression.
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Academic Article
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Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure.
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Academic Article
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High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis.
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Concept
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Acute Kidney Injury
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Academic Article
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Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis.
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Academic Article
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Acute Kidney Injury Instigates Malignant Renal Cell Carcinoma via CXCR2 in Mice with Inactivated Trp53 and Pten in Proximal Tubular Kidney Epithelial Cells.
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