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CHEN, JUNJIE

One or more keywords matched the following items that are connected to CHEN, JUNJIE

Item Type	Name
Academic Article	Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains.
Concept	Peptides
Concept	Intracellular Signaling Peptides and Proteins
Academic Article	Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways.
Academic Article	RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.
Academic Article	DNA-damage checkpoints: location, location, location.
Academic Article	The 53BP1-EXPAND1 connection in chromatin structure regulation.
Academic Article	Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX.
Academic Article	Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.
Academic Article	Early events in the DNA damage response.
Academic Article	Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis.
Academic Article	MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.
Academic Article	MEMO1, a new IRS1-interacting protein, induces epithelial-mesenchymal transition in mammary epithelial cells.
Academic Article	RIF1 counteracts BRCA1-mediated end resection during DNA repair.
Academic Article	53BP1 is required for class switch recombination.
Academic Article	Genomic instability in laminopathy-based premature aging.
Academic Article	53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice.
Academic Article	Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.
Academic Article	Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair.
Academic Article	When loose ends finally meet.
Academic Article	Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage.
Academic Article	A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
Academic Article	Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8.
Academic Article	DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.
Academic Article	p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice.
Academic Article	The tandem BRCT domain of 53BP1 is not required for its repair function.
Academic Article	Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells.
Academic Article	Differences in DNA double strand breaks repair in male germ cell types: lessons learned from a differential expression of Mdc1 and 53BP1.
Academic Article	CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response.
Academic Article	MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells.
Academic Article	Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1.

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