Item Type | Name |
Academic Article
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Open-label, randomized comparison of itraconazole versus caspofungin for prophylaxis in patients with hematologic malignancies.
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Academic Article
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Development of Varicella-Zoster virus infection in patients with chronic myelogenous leukemia treated with imatinib mesylate.
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Academic Article
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Phase II study of alemtuzumab in combination with pentostatin in patients with T-cell neoplasms.
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Concept
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Aged, 80 and over
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Concept
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Aged
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Concept
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Middle Aged
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Academic Article
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Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease: clinical significance and comparison of chomosomal abnormalities in SM and AHNMD components.
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Academic Article
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Interim analysis of safety and efficacy of ruxolitinib in patients with myelofibrosis and low platelet counts.
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Academic Article
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A prognostic model for survival in chronic lymphocytic leukaemia based on p53 expression.
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Academic Article
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Comorbidities predict worse prognosis in patients with primary myelofibrosis.
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Academic Article
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Prognostic significance of cellular vascular endothelial growth factor expression in chronic phase chronic myeloid leukemia.
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Academic Article
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Treatment of Philadelphia chromosome-positive chronic myelogenous leukemia with weekly polyethylene glycol formulation of interferon-alpha-2b and low-dose cytosine arabinoside.
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Academic Article
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Outcome with the hyper-CVAD regimens in lymphoblastic lymphoma.
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Academic Article
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Interferon alpha therapy for patients with essential thrombocythemia: final results of a phase II study initiated in 1986.
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Academic Article
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Adaptive randomized study of idarubicin and cytarabine alone or with interleukin-11 as induction therapy in patients aged 50 or above with acute myeloid leukemia or high-risk myelodysplastic syndromes.
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Academic Article
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Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate.
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Academic Article
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Adult acute megakaryocytic leukemia: an analysis of 37 patients treated at M.D. Anderson Cancer Center.
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Academic Article
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Eradication of minimal residual disease in hairy cell leukemia.
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Academic Article
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Chemoimmunotherapy with hyper-CVAD plus rituximab for the treatment of adult Burkitt and Burkitt-type lymphoma or acute lymphoblastic leukemia.
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Academic Article
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A novel translocation t(3;21)(p21;q22) in acute myelogenous leukemia preceding a late-appearing Philadelphia chromosome.
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Academic Article
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Frequency and clinical significance of BCR-ABL mutations in patients with chronic myeloid leukemia treated with imatinib mesylate.
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Academic Article
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EXEL-0862, a novel tyrosine kinase inhibitor, induces apoptosis in vitro and ex vivo in human mast cells expressing the KIT D816V mutation.
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Academic Article
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Activity of 9-nitro-camptothecin, an oral topoisomerase I inhibitor, in myelodysplastic syndrome and chronic myelomonocytic leukemia.
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Academic Article
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Outcome of patients with Philadelphia chromosome-positive chronic myelogenous leukemia post-imatinib mesylate failure.
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Academic Article
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Experience with oral interferon-alpha in patients with essential thrombocythemia and polycythemia vera.
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Academic Article
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Phase 1 study of lonafarnib (SCH 66336) and imatinib mesylate in patients with chronic myeloid leukemia who have failed prior single-agent therapy with imatinib.
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Academic Article
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Granulocytic sarcoma with massive scalp involvement.
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Academic Article
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PEG-IFN-alpha-2b therapy in BCR-ABL-negative myeloproliferative disorders: final result of a phase 2 study.
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Academic Article
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Thrombosis of the corpora cavernosa complicating lenalidomide therapy of myelofibrosis.
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Academic Article
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Effective treatment of acute promyelocytic leukemia with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab ozogamicin.
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Academic Article
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Utility of the World Heath Organization classification criteria for the diagnosis of systemic mastocytosis in bone marrow.
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Academic Article
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Alemtuzumab therapy for hypereosinophilic syndrome and chronic eosinophilic leukemia.
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Academic Article
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Cytogenetic abnormalities in essential thrombocythemia at presentation and transformation.
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Academic Article
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Superior outcome with hypomethylating therapy in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome and chromosome 5 and 7 abnormalities.
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Academic Article
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Mycotic pulmonary artery aneurysm due to Aspergillus infection in a patient with leukemia: case report and review of the literature.
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Academic Article
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Chemoimmunotherapy with a modified hyper-CVAD and rituximab regimen improves outcome in de novo Philadelphia chromosome-negative precursor B-lineage acute lymphoblastic leukemia.
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Academic Article
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Phase II study of sunitinib in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis.
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Academic Article
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Characteristics and outcome of patients with acute myeloid leukemia refractory to 1 cycle of high-dose cytarabine-based induction chemotherapy.
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Academic Article
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Competing cell clones in myeloproliferative neoplasm.
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Academic Article
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Outcome of patients with chronic myeloid leukemia with multiple ABL1 kinase domain mutations receiving tyrosine kinase inhibitor therapy.
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Academic Article
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Dasatinib-responsive mast cell neoplasms as initial presentation of chronic myelogenous leukemia in blast phase.
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Academic Article
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Comparison of thalidomide and lenalidomide as therapy for myelofibrosis.
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Academic Article
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Acute lymphoblastic leukemia arising in post-polycythemic myelofibrosis: a rare entity.
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Academic Article
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Therapy with the histone deacetylase inhibitor pracinostat for patients with myelofibrosis.
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Academic Article
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Prognostic model to identify patients with myelofibrosis at the highest risk of transformation to acute myeloid leukemia.
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Academic Article
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A phase II open-label study of the intravenous administration of homoharringtonine in the treatment of myelodysplastic syndrome.
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Academic Article
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Metastatic splenic angiosarcoma presenting with thrombocytopenia and bone marrow fibrosis mimicking idiopathic thrombocytopenic purpura and primary myelofibrosis: a diagnostic challenge.
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Academic Article
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Phase I evaluation of XL019, an oral, potent, and selective JAK2 inhibitor.
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Academic Article
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Myelodysplastic/myeloproliferative neoplasms, unclassifiable (MDS/MPN, U): natural history and clinical outcome by treatment strategy.
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Academic Article
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Prognostic significance of Tie-1 protein expression in patients with early chronic phase chronic myeloid leukemia.
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Academic Article
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Pilot study of pegylated interferon-alpha 2b in patients with essential thrombocythemia.
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Academic Article
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Empirical examination of the neutrophil criterion (>1500 microl(-1)) currently needed to declare CR in AML.
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Academic Article
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SU5416, a small molecule tyrosine kinase receptor inhibitor, has biologic activity in patients with refractory acute myeloid leukemia or myelodysplastic syndromes.
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Academic Article
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Anagrelide and imatinib mesylate combination therapy in patients with chronic myeloproliferative disorders.
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Academic Article
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Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia.
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Academic Article
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Gemtuzumab ozogamicin, fludarabine, cytarabine and cyclosporine combination regimen in patients with CD33+ primary resistant or relapsed acute myeloid leukemia.
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Academic Article
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Phase I and pharmacodynamic study of Triapine, a novel ribonucleotide reductase inhibitor, in patients with advanced leukemia.
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Academic Article
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Analysis of the impact of imatinib mesylate therapy on the prognosis of patients with Philadelphia chromosome-positive chronic myelogenous leukemia treated with interferon-alpha regimens for early chronic phase.
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Academic Article
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High-dose imatinib mesylate therapy in newly diagnosed Philadelphia chromosome-positive chronic phase chronic myeloid leukemia.
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Academic Article
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A Phase I and pharmacokinetic study of VNP40101M, a novel sulfonylhydrazine alkylating agent, in patients with refractory leukemia.
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Academic Article
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Telomerase activity is not a prognostic factor in chronic lymphocytic leukemia.
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Academic Article
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Long-term survival benefit and improved complete cytogenetic and molecular response rates with imatinib mesylate in Philadelphia chromosome-positive chronic-phase chronic myeloid leukemia after failure of interferon-alpha.
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Academic Article
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Outcome of patients with acute myelogenous leukemia after second salvage therapy.
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Academic Article
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Sudden blastic transformation in patients with chronic myeloid leukemia treated with imatinib mesylate.
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Academic Article
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Use of all-trans retinoic acid plus arsenic trioxide as an alternative to chemotherapy in untreated acute promyelocytic leukemia.
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Academic Article
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Clofarabine and cytarabine combination as induction therapy for acute myeloid leukemia (AML) in patients 50 years of age or older.
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Academic Article
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'Idiopathic' eosinophilia with an Occult T-cell clone: prevalence and clinical course.
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Academic Article
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Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to idarubicin + high-dose Ara-C: a phase 1 study.
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Academic Article
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Levels of soluble HLA-I and beta2M in patients with acute myeloid leukemia and advanced myelodysplastic syndrome: association with clinical behavior and outcome of induction therapy.
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Academic Article
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Quantitative profiling of codon 816 KIT mutations can aid in the classification of systemic mast cell disease.
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Academic Article
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Phase I study of alternate-week administration of tipifarnib in patients with myelodysplastic syndrome.
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Academic Article
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5-Azacitidine has limited therapeutic activity in myelofibrosis.
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Academic Article
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Imatinib has limited therapeutic activity for hypereosinophilic syndrome patients with unknown or negative PDGFRalpha mutation status.
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Academic Article
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The role of cytogenetic abnormalities as a prognostic marker in primary myelofibrosis: applicability at the time of diagnosis and later during disease course.
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Academic Article
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Phase II study of imatinib mesylate as therapy for patients with systemic mastocytosis.
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Academic Article
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Treatment of myelofibrosis in younger patients: to transplant or not?
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Academic Article
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Chronic myeloid leukemia (CML) with P190 BCR-ABL: analysis of characteristics, outcomes, and prognostic significance.
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Academic Article
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Acute pulmonary failure during remission induction chemotherapy in adults with acute myeloid leukemia or high-risk myelodysplastic syndrome.
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Academic Article
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Allogeneic stem cell transplantation for myelofibrosis with leukemic transformation.
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Academic Article
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Experience with everolimus (RAD001), an oral mammalian target of rapamycin inhibitor, in patients with systemic mastocytosis.
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Academic Article
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Aberrant myeloid maturation identified by flow cytometry in primary myelofibrosis.
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Academic Article
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Current event-free survival after sequential tyrosine kinase inhibitor therapy for chronic myeloid leukemia.
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Academic Article
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A phase 1-2 study of a farnesyltransferase inhibitor, tipifarnib, combined with idarubicin and cytarabine for patients with newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndrome.
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Academic Article
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Phase 2 study of the JAK kinase inhibitor ruxolitinib in patients with refractory leukemias, including postmyeloproliferative neoplasm acute myeloid leukemia.
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Academic Article
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Therapeutic effects of ruxolitinib in patients with myelofibrosis without clinically significant splenomegaly.
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Academic Article
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Long-term follow-up of patients with hypereosinophilic syndrome treated with Alemtuzumab, an anti-CD52 antibody.
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Academic Article
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Chromosome 5q deletion is extremely rare in patients with myelofibrosis.
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Academic Article
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Outcome after failure of second generation tyrosine kinase inhibitors treatment as first-line therapy for patients with chronic myeloid leukemia.
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Academic Article
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Molecular analysis of patients with polycythemia vera or essential thrombocythemia receiving pegylated interferon a-2a.
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Academic Article
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Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies.
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Academic Article
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Patients with polycythemia vera and essential thrombocythemia with prior malignancy do not have significantly worse outcome.
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Academic Article
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Similar outcome of patients with chronic myeloid leukemia treated with imatinib in or out of clinical trials.
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Academic Article
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Bone marrow fibrosis in patients with primary myelodysplastic syndromes has prognostic value using current therapies and new risk stratification systems.
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Academic Article
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Synchronous primary cancers of the breast and cervix: planning multidisciplinary primary treatment [clinico-pathological conference].
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Academic Article
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High expression of the receptor tyrosine kinase Tie-1 in acute myeloid leukemia and myelodysplastic syndrome.
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Academic Article
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Neutrophilic-chronic myeloid leukemia: low levels of p230 BCR/ABL mRNA and undetectable BCR/ABL protein may predict an indolent course.
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Academic Article
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Clinical relevance of vascular endothelial growth factor receptors 1 and 2 in acute myeloid leukaemia and myelodysplastic syndrome.
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Academic Article
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Complete cytogenetic and molecular responses to interferon-alpha-based therapy for chronic myelogenous leukemia are associated with excellent long-term prognosis.
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Academic Article
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Increased telomerase activity is associated with shorter survival in patients with chronic phase chronic myeloid leukemia.
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Academic Article
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Gemtuzumab, fludarabine, cytarabine, and cyclosporine in patients with newly diagnosed acute myelogenous leukemia or high-risk myelodysplastic syndromes.
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Academic Article
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Outcome in patients with nonleukemic granulocytic sarcoma treated with chemotherapy with or without radiotherapy.
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Academic Article
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Mylotarg, fludarabine, cytarabine (ara-C), and cyclosporine (MFAC) regimen as post-remission therapy in acute myelogenous leukemia.
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Academic Article
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Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate.
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Academic Article
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Survival advantage with imatinib mesylate therapy in chronic-phase chronic myelogenous ;eukemia (CML-CP) after IFN-alpha failure and in late CML-CP, comparison with historical controls.
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Academic Article
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Phase I and pharmacokinetic study of a low-clearance, unilamellar liposomal formulation of lurtotecan, a topoisomerase 1 inhibitor, in patients with advanced leukemia.
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Academic Article
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Results of imatinib mesylate therapy in chronic myelogenous leukaemia with variant Philadelphia chromosome.
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Academic Article
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Imatinib mesylate therapy may overcome the poor prognostic significance of deletions of derivative chromosome 9 in patients with chronic myelogenous leukemia.
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Academic Article
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Survival benefit with imatinib mesylate therapy in patients with accelerated-phase chronic myelogenous leukemia--comparison with historic experience.
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Academic Article
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Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate.
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Academic Article
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Phase 1 study of ABT-751, a novel microtubule inhibitor, in patients with refractory hematologic malignancies.
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Academic Article
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Phase I study of cloretazine (VNP40101M), a novel sulfonylhydrazine alkylating agent, combined with cytarabine in patients with refractory leukemia.
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Academic Article
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T-cell prolymphocytic leukemia: a single-institution experience.
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Academic Article
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Staging of chronic myeloid leukemia in the imatinib era: an evaluation of the World Health Organization proposal.
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Academic Article
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Triapine and cytarabine is an active combination in patients with acute leukemia or myelodysplastic syndrome.
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Academic Article
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Improvement of overall and failure-free survival in stage IV follicular lymphoma: 25 years of treatment experience at The University of Texas M.D. Anderson Cancer Center.
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Academic Article
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Activity of alemtuzumab in patients with CD52-positive acute leukemia.
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Academic Article
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Validation of the European Prognostic Index for younger adult patients with acute myeloid leukaemia in first relapse.
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Academic Article
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Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia.
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Academic Article
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High occurrence of JAK2 V617 mutation in refractory anemia with ringed sideroblasts associated with marked thrombocytosis.
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Academic Article
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The burden of fatigue and quality of life in myeloproliferative disorders (MPDs): an international Internet-based survey of 1179 MPD patients.
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Academic Article
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Phase II study of low-dose decitabine in combination with imatinib mesylate in patients with accelerated or myeloid blastic phase of chronic myelogenous leukemia.
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Academic Article
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Monocytosis is an adverse prognostic factor for survival in younger patients with primary myelofibrosis.
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Academic Article
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Treatment of systemic mastocytosis with denileukin diftitox.
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Academic Article
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Prognostic interaction between thrombocytosis and JAK2 V617F mutation in the WHO subcategories of myelodysplastic/myeloproliferative disease-unclassifiable and refractory anemia with ringed sideroblasts and marked thrombocytosis.
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Academic Article
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Cytogenetic and molecular responses and outcome in chronic myelogenous leukemia: need for new response definitions?
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Academic Article
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A phase I and pharmacokinetic study of XK469R (NSC 698215), a quinoxaline phenoxypropionic acid derivative, in patients with refractory acute leukemia.
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Academic Article
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Phase II study of dasatinib in Philadelphia chromosome-negative acute and chronic myeloid diseases, including systemic mastocytosis.
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Academic Article
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A randomized study of clofarabine versus clofarabine plus low-dose cytarabine as front-line therapy for patients aged 60 years and older with acute myeloid leukemia and high-risk myelodysplastic syndrome.
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Academic Article
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Imatinib mesylate dose escalation is associated with durable responses in patients with chronic myeloid leukemia after cytogenetic failure on standard-dose imatinib therapy.
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Academic Article
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Hepatosplenic gamma-delta T-cell lymphoma: clinicopathological features and treatment.
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Academic Article
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Plasma levels of JAK2 mRNA in patients with chronic myeloproliferative diseases with and without V617F mutation: implications for prognosis and disease biology.
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Academic Article
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Imatinib mesylate therapy for polycythemia vera: final result of a phase II study initiated in 2001.
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Academic Article
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A phase I clinical trial of darinaparsin in patients with refractory solid tumors.
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Academic Article
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Pomalidomide is active in the treatment of anemia associated with myelofibrosis.
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Academic Article
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Lenalidomide plus prednisone results in durable clinical, histopathologic, and molecular responses in patients with myelofibrosis.
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Academic Article
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Pegylated interferon alfa-2a yields high rates of hematologic and molecular response in patients with advanced essential thrombocythemia and polycythemia vera.
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Academic Article
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Efficacy and safety of intravenous voriconazole and intravenous itraconazole for antifungal prophylaxis in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome.
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Academic Article
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Conventional and experimental drug therapy in myelofibrosis with myeloid metaplasia.
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Academic Article
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Phase II study of obatoclax mesylate (GX15-070), a small-molecule BCL-2 family antagonist, for patients with myelofibrosis.
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Academic Article
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Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis.
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Academic Article
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Immune modulation of minimal residual disease in early chronic phase chronic myelogenous leukemia: a randomized trial of frontline high-dose imatinib mesylate with or without pegylated interferon alpha-2b and granulocyte-macrophage colony-stimulating factor.
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Academic Article
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The clinical significance of achieving different levels of cytogenetic response in patients with chronic phase chronic myeloid leukemia after failure to front-line therapy: is complete cytogenetic response the only desirable endpoint?
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Academic Article
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Analysis of outcomes in adolescents and young adults with chronic myelogenous leukemia treated with upfront tyrosine kinase inhibitor therapy.
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Academic Article
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A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis.
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Academic Article
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The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis.
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Academic Article
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Significance of cytogenetic abnormalities in patients with polycythemia vera.
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Academic Article
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Early responses predict better outcomes in patients with newly diagnosed chronic myeloid leukemia: results with four tyrosine kinase inhibitor modalities.
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Academic Article
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The clinical importance of moderate/severe bone marrow fibrosis in patients with therapy-related myelodysplastic syndromes.
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Academic Article
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Primary autoimmune myelofibrosis (MF) with high-grade peripheral T-cell lymphoma (PTCL) NOS.
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Academic Article
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Single agent bevacizumab for myelofibrosis: results of the Myeloproliferative Disorders Research Consortium Trial.
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Academic Article
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Modest activity of pomalidomide in patients with myelofibrosis and significant anemia.
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Academic Article
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Significance of deeper molecular responses in patients with chronic myeloid leukemia in early chronic phase treated with tyrosine kinase inhibitors.
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Academic Article
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Phase I clinical, pharmacokinetic, and pharmacodynamic study of the Akt-inhibitor triciribine phosphate monohydrate in patients with advanced hematologic malignancies.
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Academic Article
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Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I.
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Academic Article
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Imatinib therapy in a patient with suspected chronic neutrophilic leukemia and FIP1L1-PDGFRA rearrangement.
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Academic Article
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A phase 2 study of ruxolitinib, an oral JAK1 and JAK2 Inhibitor, in patients with advanced polycythemia vera who are refractory or intolerant to hydroxyurea.
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Academic Article
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A phase I and pharmacodynamic study of AT9283, a small-molecule inhibitor of aurora kinases in patients with relapsed/refractory leukemia or myelofibrosis.
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Academic Article
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Atypical chronic myeloid leukemia is clinically distinct from unclassifiable myelodysplastic/myeloproliferative neoplasms.
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Academic Article
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Phase II study of pomalidomide in combination with prednisone in patients with myelofibrosis and significant anemia.
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Academic Article
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Flow cytometric immunophenotypic analysis of systemic mastocytosis involving bone marrow.
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Academic Article
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Clinical significance of microcytosis in patients with primary myelofibrosis.
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Academic Article
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Experience with alemtuzumab plus rituximab in patients with relapsed and refractory lymphoid malignancies.
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Academic Article
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Result of high-dose imatinib mesylate in patients with Philadelphia chromosome-positive chronic myeloid leukemia after failure of interferon-alpha.
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Academic Article
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Fractionated cyclophosphamide, vincristine, liposomal daunorubicin, and dexamethasone plus rituximab and granulocyte-macrophage-colony stimulating factor (GM-CSF) alternating with methotrexate and cytarabine plus rituximab and GM-CSF in patients with Richter syndrome or fludarabine-refractory chronic lymphocytic leukemia.
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Academic Article
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Clinical relevance of VEGF receptors 1 and 2 in patients with chronic myelogenous leukemia.
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Academic Article
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Telomerase activity is prognostic in pediatric patients with acute myeloid leukemia: comparison with adult acute myeloid leukemia.
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Academic Article
|
Adaptive randomized study of idarubicin and cytarabine versus troxacitabine and cytarabine versus troxacitabine and idarubicin in untreated patients 50 years or older with adverse karyotype acute myeloid leukemia.
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Academic Article
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Management of patients with systemic mastocytosis: review of M. D. Anderson Cancer Center experience.
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Academic Article
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2-Chlorodeoxyadenosine and cytarabine combination therapy for idiopathic hypereosinophilic syndrome.
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Academic Article
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The anti-angiogenesis agent, AG-013736, has minimal activity in elderly patients with poor prognosis acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
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Academic Article
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Clinical relevance of soluble HLA-I and beta2-microglobulin levels in non-Hodgkin's lymphoma and Hodgkin's disease.
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Academic Article
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A phase II study of cloretazine (VNP40101M), a novel sulfonylhydrazine alkylating agent, in patients with very high risk relapsed acute myeloid leukemia.
|
Academic Article
|
Thalidomide therapy for myelofibrosis with myeloid metaplasia.
|
Academic Article
|
Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies.
|
Academic Article
|
Phase I/II study of subcutaneous homoharringtonine in patients with chronic myeloid leukemia who have failed prior therapy.
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Academic Article
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The haematopoietic cell transplantation comorbidity index score is predictive of early death and survival in patients over 60 years of age receiving induction therapy for acute myeloid leukaemia.
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Academic Article
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A phase II study of 5-azacitidine for patients with primary and post-essential thrombocythemia/polycythemia vera myelofibrosis.
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Academic Article
|
The natural history and treatment outcome of blast phase BCR-ABL- myeloproliferative neoplasms.
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Academic Article
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Prognostic significance of CD20 expression in adults with de novo precursor B-lineage acute lymphoblastic leukemia.
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Academic Article
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Clofarabine combinations as acute myeloid leukemia salvage therapy.
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Academic Article
|
Failure to achieve a complete hematologic response at the time of a major cytogenetic response with second-generation tyrosine kinase inhibitors is associated with a poor prognosis among patients with chronic myeloid leukemia in accelerated or blast phase.
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Academic Article
|
Prognostic impact of deletions of derivative chromosome 9 in patients with chronic myelogenous leukemia treated with nilotinib or dasatinib.
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Academic Article
|
Malignancies occurring during therapy with tyrosine kinase inhibitors (TKIs) for chronic myeloid leukemia (CML) and other hematologic malignancies.
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Academic Article
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An unusual case of aggressive systemic mastocytosis with associated refractory plasma cell myeloma.
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Academic Article
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Progressive burden of myelofibrosis in untreated patients: assessment of patient-reported outcomes in patients randomized to placebo in the COMFORT-I study.
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Academic Article
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Phase II study of troxacitabine, a novel dioxolane nucleoside analog, in patients with untreated or imatinib mesylate-resistant chronic myelogenous leukemia in blastic phase.
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Academic Article
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Imatinib mesylate therapy improves survival in patients with newly diagnosed Philadelphia chromosome-positive chronic myelogenous leukemia in the chronic phase: comparison with historic data.
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Academic Article
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Lenalidomide therapy in myelofibrosis with myeloid metaplasia.
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Academic Article
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Chromosomal abnormalities in Philadelphia chromosome negative metaphases appearing during imatinib mesylate therapy in patients with newly diagnosed chronic myeloid leukemia in chronic phase.
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Academic Article
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Dynamic model for predicting death within 12 months in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis.
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Academic Article
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Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis.
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Academic Article
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Phase I study of sorafenib in patients with refractory or relapsed acute leukemias.
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Academic Article
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Augmented hyper-CVAD based on dose-intensified vincristine, dexamethasone, and asparaginase in adult acute lymphoblastic leukemia salvage therapy.
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Academic Article
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Long-term outcomes of 107 patients with myelofibrosis receiving JAK1/JAK2 inhibitor ruxolitinib: survival advantage in comparison to matched historical controls.
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Academic Article
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Bone marrow mast cell burden and serum tryptase level as markers of response in patients with systemic mastocytosis.
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Academic Article
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Splenectomy in patients with myeloproliferative neoplasms: efficacy, complications and impact on survival and transformation.
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Academic Article
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Discrepancy in diagnosis of primary myelofibrosis between referral and tertiary care centers.
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Academic Article
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Tyrosine kinase inhibitors as initial therapy for patients with chronic myeloid leukemia in accelerated phase.
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Academic Article
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Acute myeloid leukemia after myelodysplastic syndrome and failure of therapy with hypomethylating agents: an emerging entity with a poor prognosis.
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Academic Article
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Characteristics and outcomes of patients with multiple myeloma who develop therapy-related myelodysplastic syndrome, chronic myelomonocytic leukemia, or acute myeloid leukemia.
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Academic Article
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Clinical characteristics and outcomes in patients with acute promyelocytic leukaemia and hyperleucocytosis.
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Academic Article
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A phase I/II study of the Janus kinase (JAK)1 and 2 inhibitor ruxolitinib in patients with relapsed or refractory acute myeloid leukemia.
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Academic Article
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A phase I, open-label, multi-center study of the JAK2 inhibitor AZD1480 in patients with myelofibrosis.
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Academic Article
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Ruxolitinib versus standard therapy for the treatment of polycythemia vera.
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Academic Article
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Phase II evaluation of IPI-926, an oral Hedgehog inhibitor, in patients with myelofibrosis.
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Academic Article
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Increased likelihood of post-polycythemia vera myelofibrosis in Ph-negative MPN patients with chromosome 12 abnormalities.
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Academic Article
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Phase I study of S-trans, trans-farnesylthiosalicylic acid (salirasib), a novel oral RAS inhibitor in patients with refractory hematologic malignancies.
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Academic Article
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Limitations of fibrosis grade as diagnostic criteria for post polycythemia vera and essential thrombocytosis myelofibrosis.
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Academic Article
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Insights from response to tyrosine kinase inhibitor therapy in a rare myeloproliferative neoplasm with CALR mutation and BCR-ABL1.
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Academic Article
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Association of lymphoid malignancies and Philadelphia-chromosome negative myeloproliferative neoplasms: Clinical characteristics, therapy and outcome.
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Academic Article
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A pooled analysis of overall survival in COMFORT-I and COMFORT-II, 2 randomized phase III trials of ruxolitinib for the treatment of myelofibrosis.
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Academic Article
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Chronic myelogenous leukemia in patients with MPL or JAK2 mutation-positive myeloproliferative neoplasm.
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Academic Article
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Ruxolitinib in combination with lenalidomide as therapy for patients with myelofibrosis.
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Academic Article
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Correlation of mutation profile and response in patients with myelofibrosis treated with ruxolitinib.
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Academic Article
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Jumping Translocations in Myeloid Malignancies Associated With Treatment Resistance and Poor Survival.
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Academic Article
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Therapeutic benefit of decitabine, a hypomethylating agent, in patients with high-risk primary myelofibrosis and myeloproliferative neoplasm in accelerated or blastic/acute myeloid leukemia phase.
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Academic Article
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Primary myelofibrosis associated glomerulopathy: significant improvement after therapy with ruxolitinib.
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Academic Article
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Long-term follow-up of a phase 2 study of chemotherapy plus dasatinib for the initial treatment of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
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Academic Article
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Genes Involved in Maintaining the Bone Marrow Stroma Are Dysregulated in Patients with Myelofibrosis: Lenalidomide Treatment Up-regulates SOCS3.
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Academic Article
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Long-term molecular and cytogenetic response and survival outcomes with imatinib 400 mg, imatinib 800 mg, dasatinib, and nilotinib in patients with chronic-phase chronic myeloid leukaemia: retrospective analysis of patient data from five clinical trials.
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Academic Article
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Outcomes of Allogeneic Hematopoietic Cell Transplantation in?Patients with Myelofibrosis with Prior Exposure to Janus Kinase 1/2 Inhibitors.
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Academic Article
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A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials.
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Academic Article
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A phase II study of decitabine and gemtuzumab ozogamicin in newly diagnosed and relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome.
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Academic Article
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Chronic lymphocytic leukemia and myeloproliferative neoplasms concurrently diagnosed: clinical and biological characteristics.
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Academic Article
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DNMT3A, TET2, and JAK2 mutations in polycythemia vera following long-term remission of secondary acute myeloid leukemia.
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Academic Article
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Analysis of 2013 European LeukaemiaNet (ELN) responses in chronic phase CML across four frontline TKI modalities and impact on clinical outcomes.
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Academic Article
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Changes in quality of life and disease-related symptoms in patients with polycythemia vera receiving ruxolitinib or standard therapy.
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Academic Article
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Myeloproliferative Neoplasms With Calreticulin Mutations Exhibit Distinctive Morphologic Features.
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Academic Article
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Long-term results of a phase II trial of lenalidomide plus prednisone therapy for patients with myelofibrosis.
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Academic Article
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Clinical use of ruxolitinib in an academic medical center in unselected patients with myeloproliferative neoplasms not on clinical study.
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Academic Article
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Ruxolitinib versus best available therapy in patients with polycythemia vera: 80-week follow-up from the RESPONSE trial.
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Academic Article
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Targeted next-generation sequencing identifies a subset of idiopathic hypereosinophilic syndrome with features similar to chronic eosinophilic leukemia, not otherwise specified.
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Academic Article
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Complete remission in a patient with JAK2- and IDH2-positive myelofibrosis.
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Academic Article
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A phase I, open-label, dose-escalation, multicenter study of the JAK2 inhibitor NS-018 in patients with myelofibrosis.
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Academic Article
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The impact of anemia on overall survival in patients with myelofibrosis treated with ruxolitinib in the COMFORT studies.
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Academic Article
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Masitinib for treatment of severely symptomatic indolent systemic mastocytosis: a randomised, placebo-controlled, phase 3 study.
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Academic Article
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Phase 2 study of low-dose clofarabine plus cytarabine for patients with higher-risk myelodysplastic syndrome who have relapsed or are refractory to hypomethylating agents.
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Academic Article
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Primary analysis of a phase II open-label trial of INCB039110, a selective JAK1 inhibitor, in patients with myelofibrosis.
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Academic Article
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Markers of iron deficiency in patients with polycythemia vera receiving ruxolitinib or best available therapy.
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Academic Article
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Quality and cost comparison of powered versus manual bone marrow biopsy devices in patients with myelofibrosis.
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Academic Article
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A phase 1/2, open-label study evaluating twice-daily administration of momelotinib in myelofibrosis.
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Academic Article
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The efficacy and safety of continued hydroxycarbamide therapy versus switching to ruxolitinib in patients with polycythaemia vera: a randomized, double-blind, double-dummy, symptom study (RELIEF).
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Academic Article
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Phase 1/2 study of pacritinib, a next generation JAK2/FLT3 inhibitor, in myelofibrosis or other myeloid malignancies.
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Academic Article
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An accurate, simple prognostic model consisting of age, JAK2, CALR, and MPL mutation status for patients with primary myelofibrosis.
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Academic Article
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Chronic myeloid leukemia among patients with a history of prior malignancies: A tale of dual survivorship.
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Academic Article
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Primary autoimmune myelofibrosis: a case report and review of the literature.
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Academic Article
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Long-term outcome of acute promyelocytic leukemia treated with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab.
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Academic Article
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Ruxolitinib for symptom control in patients with chronic lymphocytic leukaemia: a single-group, phase 2 trial.
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Academic Article
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A phase 2 study of simtuzumab in patients with primary, post-polycythaemia vera or post-essential thrombocythaemia myelofibrosis.
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Academic Article
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Pegylated interferon alfa-2a in patients with essential thrombocythaemia or polycythaemia vera: a post-hoc, median 83 month follow-up of an open-label, phase 2 trial.
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Academic Article
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Haptoglobin is frequently low in patients with myelofibrosis: Clinical relevance.
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Academic Article
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The role of thrombocytapheresis in the contemporary management of hyperthrombocytosis in myeloproliferative neoplasms: A case-based review.
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Academic Article
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Bone marrow morphology is a strong discriminator between chronic eosinophilic leukemia, not otherwise specified and reactive idiopathic hypereosinophilic syndrome.
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Academic Article
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Practical Measures of Clinical Benefit With Ruxolitinib Therapy: An Exploratory Analysis of COMFORT-I.
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Academic Article
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Characteristics and clinical significance of cytogenetic abnormalities in polycythemia vera.
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Academic Article
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Morphologic and Molecular Characteristics of De Novo AML With JAK2 V617F Mutation.
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Academic Article
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Mast cell leukemia (MCL): Clinico-pathologic and molecular features and survival outcome.
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Academic Article
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Patients with post-essential thrombocythemia and post-polycythemia vera differ from patients with primary myelofibrosis.
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Academic Article
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Novel hematological parameters for the evaluation of patients with myeloproliferative neoplasms: the immature platelet and reticulocyte fractions.
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Academic Article
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3q26.2/EVI1 rearrangement is associated with poor prognosis in classical Philadelphia chromosome-negative myeloproliferative neoplasms.
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Academic Article
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Ruxolitinib reduces JAK2 p.V617F allele burden in patients with polycythemia vera enrolled in the RESPONSE study.
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Academic Article
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Characteristics and outcomes of older patients with secondary acute myeloid leukemia according to treatment approach.
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Academic Article
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A phase 2 study of momelotinib, a potent JAK1 and JAK2 inhibitor, in patients with polycythemia vera or essential thrombocythemia.
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Academic Article
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Clonal evolution and outcomes in myelofibrosis after ruxolitinib discontinuation.
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Academic Article
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Prognostic factors and survival outcomes in patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era: Cohort study of 477 patients.
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Academic Article
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A phase 1 study of the Janus kinase 2 (JAK2)V617F inhibitor, gandotinib (LY2784544), in patients with primary myelofibrosis, polycythemia vera, and essential thrombocythemia.
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Academic Article
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A phase II trial of ruxolitinib in combination with azacytidine in myelodysplastic syndrome/myeloproliferative neoplasms.
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Academic Article
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Life after ponatinib failure: outcomes of chronic and accelerated phase CML patients who discontinued ponatinib in the salvage setting.
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Academic Article
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Myeloid/lymphoid neoplasms with FGFR1 rearrangement.
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Academic Article
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Ruxolitinib for essential thrombocythemia refractory to or intolerant of hydroxyurea: long-term phase 2 study results.
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Academic Article
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JAK2V617F detection and allele burden measurement in saliva vs. peripheral blood in patients with myelofibrosis.
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Academic Article
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Prognostic significance of additional chromosomal abnormalities at the time of diagnosis in patients with chronic myeloid leukemia treated with frontline tyrosine kinase inhibitors.
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Academic Article
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Efficacy and safety of ruxolitinib after and versus interferon use in the RESPONSE studies.
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Academic Article
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Long-term effects of ruxolitinib versus best available therapy on bone marrow fibrosis in patients with myelofibrosis.
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Academic Article
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MYC protein expression is an important prognostic factor in acute myeloid leukemia.
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Academic Article
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Significance of thrombocytopenia in patients with primary and postessential thrombocythemia/polycythemia vera myelofibrosis.
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Academic Article
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Bone marrow findings in blast phase of polycythemia vera.
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Academic Article
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Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations.
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Academic Article
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Patient characteristics and outcomes in adolescents and young adults with classical Philadelphia chromosome-negative myeloproliferative neoplasms.
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Academic Article
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Sensitive PCR-based monitoring and early detection of relapsed JAK2 V617F myelofibrosis following transplantation.
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Academic Article
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Momelotinib versus best available therapy in patients with myelofibrosis previously treated with ruxolitinib (SIMPLIFY 2): a randomised, open-label, phase 3 trial.
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Academic Article
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Liposomal Grb2 antisense oligodeoxynucleotide (BP1001) in patients with refractory or relapsed haematological malignancies: a single-centre, open-label, dose-escalation, phase 1/1b trial.
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Academic Article
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Association of bone marrow fibrosis with inferior survival outcomes in chronic myelomonocytic leukemia.
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Academic Article
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Pentraxin-3 plasma levels correlate with tumour burden and overall survival in patients with primary myelofibrosis.
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Academic Article
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Comprehensive haematological control with ruxolitinib in patients with polycythaemia vera resistant to or intolerant of hydroxycarbamide.
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Academic Article
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Sustained-release ruxolitinib: Findings from a phase 1 study in healthy subjects and a phase 2 study in patients with myelofibrosis.
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Academic Article
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A multimodality work-up of patients with Hypereosinophilia.
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Academic Article
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Cladribine and low-dose cytarabine alternating with decitabine as front-line therapy for elderly patients with acute myeloid leukaemia: a phase 2 single-arm trial.
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Academic Article
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Phase I study of ruxolitinib in previously treated patients with low or intermediate-1 risk myelodysplastic syndrome with evidence of NF-kB activation.
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Academic Article
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A phase Ib study to assess the efficacy and safety of vismodegib in combination with ruxolitinib in patients with intermediate- or high-risk myelofibrosis.
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Academic Article
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Treatment of the myeloid/lymphoid neoplasm with FGFR1 rearrangement with FGFR1 inhibitor.
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Academic Article
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The co-occurrence of driver mutations in chronic myeloproliferative neoplasms.
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Academic Article
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Unique Case of Myeloproliferative Neoplasm with Two Rare Clonal Abnormalities: Rare JAK2 Exon 12 Mutation and Rare e14a3 (b3a3) BCR/ABL Fusion Transcript.
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Academic Article
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A phase 2 study of pracinostat combined with ruxolitinib in patients with myelofibrosis.
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Academic Article
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Utility of JAK2 V617F allelic burden in distinguishing chronic myelomonocytic Leukemia from Primary myelofibrosis with monocytosis.
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Academic Article
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Analysis of cardiovascular and arteriothrombotic adverse events in chronic-phase CML patients after frontline TKIs.
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Academic Article
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Mutational landscape of myelodysplastic/myeloproliferative neoplasm-unclassifiable.
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Academic Article
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A phase 2 study of ruxolitinib in combination with azacitidine in patients with myelofibrosis.
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Academic Article
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Ruxolitinib therapy is associated with improved renal function in patients with primary myelofibrosis.
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Academic Article
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Outcomes of patients with chronic phase chronic myeloid leukemia (CML-CP) after discontinuation of frontline ponatinib therapy.
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Academic Article
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The evolving understanding of prognosis in post-essential thrombocythemia myelofibrosis and post-polycythemia vera myelofibrosis vs primary myelofibrosis.
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Academic Article
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A phase 2 study of brentuximab vedotin in patients with CD30-positive advanced systemic mastocytosis.
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Academic Article
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Efficacy and safety of generic imatinib after switching from original imatinib in patients treated for chronic myeloid leukemia in the United States.
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Academic Article
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Prognostic impact of RAS-pathway mutations in patients with myelofibrosis.
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Academic Article
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Concurrent JAK2 V617F and MPL W515L in myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis.
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Academic Article
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Long-term results of frontline dasatinib in chronic myeloid leukemia.
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Academic Article
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Long-term results of a phase 2 trial of nilotinib 400?mg twice daily in newly diagnosed patients with chronic-phase chronic myeloid leukemia.
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Academic Article
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Prevalence of pulmonary hypertension in myelofibrosis.
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Academic Article
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Systematic use of fluorescence in-situ hybridisation and clinicopathological features in the screening of PDGFRB rearrangements of patients with myeloid/lymphoid neoplasms.
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Academic Article
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A phase 1/2 study of ruxolitinib and decitabine in patients with post-myeloproliferative neoplasm acute myeloid leukemia.
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Academic Article
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Fedratinib in patients with myelofibrosis previously treated with ruxolitinib: An updated analysis of the JAKARTA2 study using stringent criteria for ruxolitinib failure.
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Academic Article
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Lymphocytic variant of hypereosinophilic syndrome: A report of seven cases from a single institution.
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Academic Article
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Real-world risk assessment and treatment initiation among patients with myelofibrosis at community oncology practices in the United States.
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Academic Article
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Optimizing the Conditioning Regimen for Hematopoietic Cell Transplant in Myelofibrosis: Long-Term Results of a Prospective Phase II Clinical Trial.
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Academic Article
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Phase II trial of CPX-351 in patients with acute myeloid leukemia at high risk for induction mortality.
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Academic Article
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Hyper-CVAD regimen in combination with ofatumumab as frontline therapy for adults with Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia: a single-arm, phase 2 trial.
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Academic Article
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Phase I/II study of dasatinib in combination with decitabine in patients with accelerated or blast phase chronic myeloid leukemia.
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Academic Article
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Atypical cases of necrotizing sweet syndrome in patients with myelodysplastic syndrome and acute myeloid leukaemia.
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Academic Article
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Prognostic value of blasts in peripheral blood in myelofibrosis in the ruxolitinib era.
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Academic Article
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10-day decitabine with venetoclax for newly diagnosed intensive chemotherapy ineligible, and relapsed or refractory acute myeloid leukaemia: a single-centre, phase 2 trial.
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Academic Article
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The effect of eltrombopag in managing thrombocytopenia associated with tyrosine kinase therapy in patients with chronic myeloid leukemia and myelofibrosis.
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Academic Article
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Diagnostic Performance of Erythropoietin Levels in Polycythemia Vera: Experience at a Comprehensive Cancer Center.
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Academic Article
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MOMENTUM: momelotinib vs danazol in patients with myelofibrosis previously treated with JAKi who are symptomatic and anemic.
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Academic Article
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Clinical Significance of Bone Marrow Blast Percentage in Patients With Myelofibrosis and the Effect of Ruxolitinib Therapy.
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Academic Article
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Prognostic value of measurable residual disease after venetoclax and decitabine in acute myeloid leukemia.
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Academic Article
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Clinical, genomic, and transcriptomic differences between myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T) and myelodysplastic syndrome with ring sideroblasts (MDS-RS).
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Academic Article
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Disease and Clinical Characteristics of Patients With a Clinical Diagnosis of Essential Thrombocythemia Enrolled in the MOST Study.
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Academic Article
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Long-term results of low-intensity chemotherapy with clofarabine or cladribine combined with low-dose cytarabine alternating with decitabine in older patients with newly diagnosed acute myeloid leukemia.
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Academic Article
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Clinicopathologic correlates and natural history of atypical chronic myeloid leukemia.
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Academic Article
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Phase II study of single-agent nivolumab in patients with myelofibrosis.
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Academic Article
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Real-world patient characteristics and treatment patterns of ruxolitinib among patients with advanced essential thrombocythemia at community clinical practice.
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Academic Article
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Real-world survival of US patients with intermediate- to high-risk myelofibrosis: impact of ruxolitinib approval.
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Academic Article
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Safety and efficacy of avapritinib in advanced systemic mastocytosis: the phase 1 EXPLORER trial.
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Academic Article
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Thrombotic events and mortality risk in patients with newly diagnosed polycythemia vera or essential thrombocythemia.
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Academic Article
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Disease and Clinical Characteristics of Patients With a Clinical Diagnosis of Myelofibrosis Enrolled in the MOST Study.
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Academic Article
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Improved survival of patients with myelofibrosis in the last decade: Single-center experience.
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Academic Article
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Clinicopathologic spectrum of myeloid neoplasms with concurrent myeloproliferative neoplasm driver mutations and SRSF2 mutations.
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Academic Article
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Early intervention in myelofibrosis and impact on outcomes: A pooled analysis of the COMFORT-I and COMFORT-II studies.
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Academic Article
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MANIFEST: Pelabresib in Combination With Ruxolitinib for Janus Kinase Inhibitor Treatment-Na?ve Myelofibrosis.
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Academic Article
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Relevant Clinical Factors in Patients with Myelofibrosis on Ruxolitinib for 5 or More Years.
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