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Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma.
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Metabolic remodeling precedes mTORC1-mediated cardiac hypertrophy.
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Regenerative proliferation of differentiated cells by mTORC1-dependent paligenosis.
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Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex.
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Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming.
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TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy.
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Differential regulation of mTORC1 activation by leucine and ?-hydroxy-?-methylbutyrate in skeletal muscle of neonatal pigs.
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mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation.
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mTORC2, but not mTORC1, is required for hippocampal mGluR-LTD and associated behaviors.
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Phagocytosed photoreceptor outer segments activate mTORC1 in the retinal pigment epithelium.
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Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction.
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Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth.
Academic Article
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Viral model of maternal immune activation alters placental AMPK and mTORC1 signaling in rats.
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Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2.
Academic Article
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Mechanistic Target of Rapamycin Complex 1
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