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Metabolic remodeling precedes mTORC1-mediated cardiac hypertrophy.
Academic Article
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Regenerative proliferation of differentiated cells by mTORC1-dependent paligenosis.
Academic Article
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Structural basis for mTORC1 activation on the lysosomal membrane.
Academic Article
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Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex.
Academic Article
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TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy.
Academic Article
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Bi-allelic KICS2 mutations impair KICSTOR complex-mediated mTORC1 regulation, causing intellectual disability and epilepsy.
Academic Article
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Differential regulation of mTORC1 activation by leucine and ?-hydroxy-?-methylbutyrate in skeletal muscle of neonatal pigs.
Academic Article
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mTORC1 feedback to AKT modulates lysosomal biogenesis through MiT/TFE regulation.
Academic Article
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mTORC2, but not mTORC1, is required for hippocampal mGluR-LTD and associated behaviors.
Academic Article
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Phagocytosed photoreceptor outer segments activate mTORC1 in the retinal pigment epithelium.
Academic Article
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Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction.
Academic Article
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Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth.
Academic Article
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Viral model of maternal immune activation alters placental AMPK and mTORC1 signaling in rats.
Academic Article
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Mechanistic Target of Rapamycin Complex 1
Concept
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Mechanistic Target of Rapamycin Complex 2
Concept
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